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antibody from antibodies-online
Targeting: JARID2
JMJ
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- Antigen structure
- References [13]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN151637 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Jumonji, AT Rich Interactive Domain 2 (JARID2) (AA 1-100), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rabbit
- Host
- Rabbit
- Epitope
- N-Term, AA 1-100
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.
c-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis.
Epigenetic mechanisms underlying maternal diabetes-associated risk of congenital heart disease.
Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2.
Differential Sensitivity of Target Genes to Translational Repression by miR-17~92.
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.
HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines.
Jarid2 is induced by TCR signalling and controls iNKT cell maturation.
Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.
Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells.
REST-mediated recruitment of polycomb repressor complexes in mammalian cells.
A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.
Schneider E, Staffas A, Röhner L, Malmberg ED, Ashouri A, Krowiorz K, Pochert N, Miller C, Wei SY, Arabanian L, Buske C, Döhner H, Bullinger L, Fogelstrand L, Heuser M, Döhner K, Xiang P, Ruschmann J, Petriv OI, Heravi-Moussavi A, Hansen CL, Hirst M, Humphries RK, Rouhi A, Palmqvist L, Kuchenbauer F
Haematologica 2018 Feb;103(2):246-255
Haematologica 2018 Feb;103(2):246-255
c-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis.
Qu Y, Yang Q, Liu J, Shi B, Ji M, Li G, Hou P
Theranostics 2017;7(7):2092-2107
Theranostics 2017;7(7):2092-2107
Epigenetic mechanisms underlying maternal diabetes-associated risk of congenital heart disease.
Basu M, Zhu JY, LaHaye S, Majumdar U, Jiao K, Han Z, Garg V
JCI insight 2017 Oct 19;2(20)
JCI insight 2017 Oct 19;2(20)
Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2.
Fantini D, Huang S, Asara JM, Bagchi S, Raychaudhuri P
Molecular biology of the cell 2017 Jan 1;28(1):192-200
Molecular biology of the cell 2017 Jan 1;28(1):192-200
Differential Sensitivity of Target Genes to Translational Repression by miR-17~92.
Jin HY, Oda H, Chen P, Yang C, Zhou X, Kang SG, Valentine E, Kefauver JM, Liao L, Zhang Y, Gonzalez-Martin A, Shepherd J, Morgan GJ, Mondala TS, Head SR, Kim PH, Xiao N, Fu G, Liu WH, Han J, Williamson JR, Xiao C
PLoS genetics 2017 Feb;13(2):e1006623
PLoS genetics 2017 Feb;13(2):e1006623
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.
Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova TB, Anil-Kirmizitas B, Bassett A, Kooistra SM, Agger K, Helin K, Heard E, Brockdorff N
Nature communications 2016 Nov 28;7:13661
Nature communications 2016 Nov 28;7:13661
HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
Yoon SJ, Foley JW, Baker JC
Nature communications 2015 Mar 16;6:6546
Nature communications 2015 Mar 16;6:6546
JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines.
Tange S, Oktyabri D, Terashima M, Ishimura A, Suzuki T
PloS one 2014;9(12):e115684
PloS one 2014;9(12):e115684
Jarid2 is induced by TCR signalling and controls iNKT cell maturation.
Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A
Nature communications 2014 Aug 8;5:4540
Nature communications 2014 Aug 8;5:4540
Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.
Holdt LM, Hoffmann S, Sass K, Langenberger D, Scholz M, Krohn K, Finstermeier K, Stahringer A, Wilfert W, Beutner F, Gielen S, Schuler G, Gäbel G, Bergert H, Bechmann I, Stadler PF, Thiery J, Teupser D
PLoS genetics 2013;9(7):e1003588
PLoS genetics 2013;9(7):e1003588
Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells.
Banaszynski LA, Wen D, Dewell S, Whitcomb SJ, Lin M, Diaz N, Elsässer SJ, Chapgier A, Goldberg AD, Canaani E, Rafii S, Zheng D, Allis CD
Cell 2013 Sep 26;155(1):107-20
Cell 2013 Sep 26;155(1):107-20
REST-mediated recruitment of polycomb repressor complexes in mammalian cells.
Dietrich N, Lerdrup M, Landt E, Agrawal-Singh S, Bak M, Tommerup N, Rappsilber J, Södersten E, Hansen K
PLoS genetics 2012;8(3):e1002494
PLoS genetics 2012;8(3):e1002494
A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.
Shirato H, Ogawa S, Nakajima K, Inagawa M, Kojima M, Tachibana M, Shinkai Y, Takeuchi T
The Journal of biological chemistry 2009 Jan 9;284(2):733-9
The Journal of biological chemistry 2009 Jan 9;284(2):733-9
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- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
