FNab09479

antibody from FineTest Biotech

Targeting: WDFY3 ALFY, KIAA0993, ZFYVE25

ELISA

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab09479 - Provider product page
Provider: FineTest Biotech
Product name: WDFY3 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: WD repeat and FYVE domain containin g 3
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

WDFY3 protein structure - FNab09479 shown in red.