Tissue expression
Cell line expression
Protein structure
WDFY3
WD repeat and FYVE domain containing 3ALFY, KIAA0993, ZFYVE25
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
Top validated antibodies |
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| antibodies-online | 6 references | Polyclonal |
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| Novus Biologicals | 6 references | Polyclonal |
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| Proteintech Group | 2 references | Polyclonal |
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| LSBio | Polyclonal |
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| Biorbyt | Polyclonal |
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