BS8171

antibody from Bioworld Technology, Inc
Targeting: IMPA1 IMPA
Provider product page for BS8171
Western blot
Immunohistochemistry

Antibody data

Product number
BS8171 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IMPA1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IMPA1.
Description
IMPA1, also known as Myo-inositol monophosphatase 1, is responsible for the procurement of inositol that is required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 exists as a homodimer and has been identified as the pharmacological target for lithium action in the brain. IMPA1 is the principal enzyme of the phosphatidyl inositol signaling pathway, and inhibition of inositol monophosphatase hydrolysis may underlie the anti-manic and anti-depressant actions of Li+. Studies indicate that a variation in the 277 codon coding region of the IMPA1 gene has not been observed in manic-depressive patients, therefore suggesting that polymorphisms or mutations in the noncoding regions of this gene may influence the lithium response in psychiatric patients.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IMPA1 protein structure - BS8171 shown in red.