BS7064

antibody from Bioworld Technology, Inc
Targeting: ADAM17 CD156B, cSVP, TACE
Provider product page for BS7064

Antibody data

Product number
BS7064 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Cleaved ADAM17 (R215) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 180-230 of Human Cleaved-ADAM17.
Description
Tumor necrosis factor ÉÇ (TNFÉÇ), also known as lymphotoxin, is a pleiotropic cytokine. TNFÏ«, also known as cachetin, is a cytokine that binds to the same receptors, producing an array of effects similar to those of TNFÉÇ. TNFÉÇ and TNFÏ« share 30% amino acid homology and have similar biological activities. TNFÉÇ is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFÏ« is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFÉÇ and TNFÏ« can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFÏ« converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFÏ« precursor to release soluble TNFÏ«.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ADAM17 protein structure - BS7064 shown in red.