Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AFC-014CL - Provider product page
- Provider
- Creative Biolabs
- Product name
- Afuco? Anti-Human ADAM17 ADCC Recombinant Antibody, ADCC Enhanced
- Antibody type
- Monoclonal
- Description
- Anti-ADAM17 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco? platform. Anti-TACE (ADAM17) antibodies are disclosed that for the first time in the art are capable of binding to TACE, of acting as antagonists of one or more its biological activities, in particular by binding to TACE in a cross domain binding mode in which residues in both the catalytic domain and in the cysteine rich/disintegrin domains (Dis-Cys) are involved in antibody binding to TACE, helping to improve the specificity of the antibody binding and/or helping to improve inhibition of TACE biological activity. The therapeutic uses of the antibodies, in particular for the treatment of cancer are disclosed.
- Reactivity
- Human
- Host
- Human
- Storage
- Store at ¨C20 or -70¡ãC upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
No comments: Submit comment
No validations: Submit validation data