AFC-014CL

antibody from Creative Biolabs

Targeting: ADAM17 CD156B, cSVP, TACE

No application information provided.

Antibody Data

Product number

AFC-014CL

Provider

Creative Biolabs

Product name

Afuco? Anti-Human ADAM17 ADCC Recombinant Antibody, ADCC Enhanced

Antibody type

Monoclonal

Description

Anti-ADAM17 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco? platform. Anti-TACE (ADAM17) antibodies are disclosed that for the first time in the art are capable of binding to TACE, of acting as antagonists of one or more its biological activities, in particular by binding to TACE in a cross domain binding mode in which residues in both the catalytic domain and in the cysteine rich/disintegrin domains (Dis-Cys) are involved in antibody binding to TACE, helping to improve the specificity of the antibody binding and/or helping to improve inhibition of TACE biological activity. The therapeutic uses of the antibodies, in particular for the treatment of cancer are disclosed.

Reactivity

Human

Host

Human

Storage

Store at ¨C20 or -70¡ãC upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.