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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB9716 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB9716, RRID:AB_1673434
- Product name
- ADAM17 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ADAM17.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter.
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor.
An essential role for ectodomain shedding in mammalian development.
Mizui Y, Yamazaki K, Sagane K, Tanaka I
Gene 1999 Jun 11;233(1-2):67-74
Gene 1999 Jun 11;233(1-2):67-74
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor.
Buxbaum JD, Liu KN, Luo Y, Slack JL, Stocking KL, Peschon JJ, Johnson RS, Castner BJ, Cerretti DP, Black RA
The Journal of biological chemistry 1998 Oct 23;273(43):27765-7
The Journal of biological chemistry 1998 Oct 23;273(43):27765-7
An essential role for ectodomain shedding in mammalian development.
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA
Science (New York, N.Y.) 1998 Nov 13;282(5392):1281-4
Science (New York, N.Y.) 1998 Nov 13;282(5392):1281-4
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of ADAM17 expression in HeLa (lanes 1, 3) and Jurkat (lanes 2, 4) whole cell lysate in the absense (1, 2) and presense (3, 4) of blocking peptide probed with ADAM17 polyclonal antibody (Cat # PAB9716) at 1 ug/mL .
