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- Product number
- MAB2129 - Provider product page
- Provider
- R&D Systems
- Product name
- Human TACE/ADAM17 Cytosolic Domain Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human TACE/ADAM17 Cytosolic Domain in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ADAM8, 9, 10, 15, or 33 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
P78536- Isotype
- IgG
- Antibody clone number
- 136121
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by α5β1 integrin in kidney mesangial cells.
ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis.
Gooz P, Dang Y, Higashiyama S, Twal WO, Haycraft CJ, Gooz M
PloS one 2012;7(3):e33350
PloS one 2012;7(3):e33350
ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis.
Göoz P, Göoz M, Baldys A, Hoffman S
Biochemical and biophysical research communications 2009 Feb 27;380(1):33-8
Biochemical and biophysical research communications 2009 Feb 27;380(1):33-8
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