Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- MAB9302 - Provider product page
- Provider
- R&D Systems
- Product name
- Human TACE/ADAM17 Ectodomain Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human TACE/ADAM17 Ectodomain in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human ADAM8, 9, 15, and recombinant mouse ADAM10 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
P78536
- Isotype
- IgG
- Antibody clone number
- 111623
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.
Nectin 4 overexpression in ovarian cancer tissues and serum: potential role as a serum biomarker.
Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
Jing Y, Ni Z, Wu J, Higgins L, Markowski TW, Kaufman DS, Walcheck B
PloS one 2015;10(3):e0121788
PloS one 2015;10(3):e0121788
Nectin 4 overexpression in ovarian cancer tissues and serum: potential role as a serum biomarker.
Derycke MS, Pambuccian SE, Gilks CB, Kalloger SE, Ghidouche A, Lopez M, Bliss RL, Geller MA, Argenta PA, Harrington KM, Skubitz AP
American journal of clinical pathology 2010 Nov;134(5):835-45
American journal of clinical pathology 2010 Nov;134(5):835-45
Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4324-31
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4324-31
Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4324-31
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4324-31
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