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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- ABIN965510 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ADAM Metallopeptidase Domain 17 (ADAM17) (Isoform 1) antibody
- Antibody type
- Polyclonal
- Antigen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ADAM17 (a disintegrin and metalloproteinase domain 17 isoform 1 preproprotein)
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1mg
- Storage
- Store at -20°C.
Submitted references Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.
Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V.
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin.
Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.
Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.
Identification of SAP97 as an intracellular binding partner of TACE.
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Shao MX, Nadel JA
Proceedings of the National Academy of Sciences of the United States of America 2005 Jan 18;102(3):767-72
Proceedings of the National Academy of Sciences of the United States of America 2005 Jan 18;102(3):767-72
Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V.
Rabie T, Strehl A, Ludwig A, Nieswandt B
The Journal of biological chemistry 2005 Apr 15;280(15):14462-8
The Journal of biological chemistry 2005 Apr 15;280(15):14462-8
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
Lee MH, Rapti M, Murphy G
The Journal of biological chemistry 2004 Oct 22;279(43):45121-9
The Journal of biological chemistry 2004 Oct 22;279(43):45121-9
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
Schäfer B, Marg B, Gschwind A, Ullrich A
The Journal of biological chemistry 2004 Nov 12;279(46):47929-38
The Journal of biological chemistry 2004 Nov 12;279(46):47929-38
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.
Allinson TM, Parkin ET, Condon TP, Schwager SL, Sturrock ED, Turner AJ, Hooper NM
European journal of biochemistry / FEBS 2004 Jun;271(12):2539-47
European journal of biochemistry / FEBS 2004 Jun;271(12):2539-47
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin.
Valeva A, Walev I, Weis S, Boukhallouk F, Wassenaar TM, Endres K, Fahrenholz F, Bhakdi S, Zitzer A
The Journal of biological chemistry 2004 Jun 11;279(24):25143-8
The Journal of biological chemistry 2004 Jun 11;279(24):25143-8
Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.
Solomon A, Rosenblum G, Gonzales PE, Leonard JD, Mobashery S, Milla ME, Sagi I
The Journal of biological chemistry 2004 Jul 23;279(30):31646-54
The Journal of biological chemistry 2004 Jul 23;279(30):31646-54
Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.
Shao MX, Ueki IF, Nadel JA
Proceedings of the National Academy of Sciences of the United States of America 2003 Sep 30;100(20):11618-23
Proceedings of the National Academy of Sciences of the United States of America 2003 Sep 30;100(20):11618-23
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A
The EMBO journal 2003 May 15;22(10):2411-21
The EMBO journal 2003 May 15;22(10):2411-21
Identification of SAP97 as an intracellular binding partner of TACE.
Peiretti F, Deprez-Beauclair P, Bonardo B, Aubert H, Juhan-Vague I, Nalbone G
Journal of cell science 2003 May 15;116(Pt 10):1949-57
Journal of cell science 2003 May 15;116(Pt 10):1949-57
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
Díaz-Rodríguez E, Montero JC, Esparís-Ogando A, Yuste L, Pandiella A
Molecular biology of the cell 2002 Jun;13(6):2031-44
Molecular biology of the cell 2002 Jun;13(6):2031-44
Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Cerretti DP, Poindexter K, Castner BJ, Means G, Copeland NG, Gilbert DJ, Jenkins NA, Black RA, Nelson N
Cytokine 1999 Aug;11(8):541-51
Cytokine 1999 Aug;11(8):541-51
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