AMM03412G

antibody from Leading Biology

Targeting: CRKL

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

AMM03412G

Provider

Leading Biology

Product name

CRKL Antibody (monoclonal) (M03)

Antibody type

Monoclonal

Description

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

4B5

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.