Tissue expression
Cell line expression
Protein structure
CRKL
CRK like proto-oncogene, adaptor proteinThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. [provided by RefSeq, Jan 2009]
Top validated antibodies |
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Novus Biologicals | ![]() |
2 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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GeneTex | ![]() |
2 references | Polyclonal |
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Abnova Corporation | ![]() |
2 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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