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- References [28]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15125-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15125-1-AP, RRID:AB_2156780
- Product name
- OGG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OGG1 antibody (Cat. #15125-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glioblastoma and its treatment are associated with extensive accelerated brain aging.
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Human CST Stimulates Base Excision Repair to Prevent the Accumulation of Oxidative DNA Damage.
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Specnuezhenide ameliorates ultraviolet-induced skin photoaging in mice by regulating the Sirtuin 3/8-Oxoguanine DNA glycosylase signal.
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
MitoQ ameliorates PM(2.5)-induced pulmonary fibrosis through regulating the mitochondria DNA homeostasis.
OGG1 inhibition suppresses African swine fever virus replication.
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling.
HIV Promotes Neurocognitive Impairment by Damaging the Hippocampal Microvessels.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Hypertrophy of Rat Skeletal Muscle Is Associated with Increased SIRT1/Akt/mTOR/S6 and Suppressed Sestrin2/SIRT3/FOXO1 Levels.
Induction of apoptosis in Ogg1-null mouse embryonic fibroblasts by GSH depletion is independent of DNA damage.
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM(2.5) from Beijing, China, in Winter.
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Potent and specific MTH1 inhibitors targeting gastric cancer.
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.
X inactivation plays a major role in the gender bias in somatic expansion in a mouse model of the fragile X-related disorders: implications for the mechanism of repeat expansion.
Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.
Ainslie AP, Klaver M, Voshart DC, Gerrits E, den Dunnen WFA, Eggen BJL, Bergink S, Barazzuol L
Aging cell 2024 Mar;23(3):e14066
Aging cell 2024 Mar;23(3):e14066
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Wen T, Xie J, Ma L, Hao Z, Zhang W, Wu T, Li L
The American journal of pathology 2024 Mar;194(3):369-383
The American journal of pathology 2024 Mar;194(3):369-383
Human CST Stimulates Base Excision Repair to Prevent the Accumulation of Oxidative DNA Damage.
Wysong BC, Schuck PL, Sridharan M, Carrison S, Murakami Y, Balakrishnan L, Stewart JA
Journal of molecular biology 2024 Aug 15;436(16):168672
Journal of molecular biology 2024 Aug 15;436(16):168672
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Specnuezhenide ameliorates ultraviolet-induced skin photoaging in mice by regulating the Sirtuin 3/8-Oxoguanine DNA glycosylase signal.
Tang N, Ren YY, Wu HT, Lv XT, Liu XT, Li QL, Wang GE, Wu YH
Photodermatology, photoimmunology & photomedicine 2023 Sep;39(5):478-486
Photodermatology, photoimmunology & photomedicine 2023 Sep;39(5):478-486
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
Su W, Gao W, Zhang R, Wang Q, Li L, Bu Q, Xu Z, Liu Z, Wang M, Zhu Y, Wu G, Zhou H, Wang X, Lu L
JHEP reports : innovation in hepatology 2023 May;5(5):100695
JHEP reports : innovation in hepatology 2023 May;5(5):100695
MitoQ ameliorates PM(2.5)-induced pulmonary fibrosis through regulating the mitochondria DNA homeostasis.
Li Y, Du Z, Li T, Ren X, Yu Y, Duan J, Sun Z
Chemosphere 2023 Jul;330:138745
Chemosphere 2023 Jul;330:138745
OGG1 inhibition suppresses African swine fever virus replication.
Fan J, Lv X, Yang S, Geng S, Yang J, Zhao Y, Zhang Z, Liu Z, Guan G, Luo J, Zeng Q, Yin H, Niu Q
Virologica Sinica 2023 Feb;38(1):96-107
Virologica Sinica 2023 Feb;38(1):96-107
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Xia J, Wu S, Wu G, Yang J
Reproductive biology 2022 Sep;22(3):100679
Reproductive biology 2022 Sep;22(3):100679
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171
Critical care (London, England) 2022 Jun 9;26(1):171
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
Jhanji M, Rao CN, Massey JC, Hope MC 3rd, Zhou X, Keene CD, Ma T, Wyatt MD, Stewart JA, Sajish M
Nature communications 2022 Jun 10;13(1):3244
Nature communications 2022 Jun 10;13(1):3244
Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling.
Cheng S, Jia H, Zhang Y, Zhou J, Chen X, Wu L, Wang J
Molecules (Basel, Switzerland) 2022 Dec 5;27(23)
Molecules (Basel, Switzerland) 2022 Dec 5;27(23)
HIV Promotes Neurocognitive Impairment by Damaging the Hippocampal Microvessels.
Sharma AL, Wang H, Zhang Z, Millien G, Tyagi M, Hongpaisan J
Molecular neurobiology 2022 Aug;59(8):4966-4986
Molecular neurobiology 2022 Aug;59(8):4966-4986
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Hypertrophy of Rat Skeletal Muscle Is Associated with Increased SIRT1/Akt/mTOR/S6 and Suppressed Sestrin2/SIRT3/FOXO1 Levels.
Gombos Z, Koltai E, Torma F, Bakonyi P, Kolonics A, Aczel D, Ditroi T, Nagy P, Kawamura T, Radak Z
International journal of molecular sciences 2021 Jul 15;22(14)
International journal of molecular sciences 2021 Jul 15;22(14)
Induction of apoptosis in Ogg1-null mouse embryonic fibroblasts by GSH depletion is independent of DNA damage.
Higgs EB, Godschalk R, Coltman NJ, Stewart GS, van Schooten FJ, Hodges NJ
Toxicology letters 2020 Oct 10;332:27-35
Toxicology letters 2020 Oct 10;332:27-35
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM(2.5) from Beijing, China, in Winter.
Niu BY, Li WK, Li JS, Hong QH, Khodahemmati S, Gao JF, Zhou ZX
International journal of environmental research and public health 2020 Jul 6;17(13)
International journal of environmental research and public health 2020 Jul 6;17(13)
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Zhang N, Zhang Y, Wu B, You S, Sun Y
Redox biology 2020 Feb;30:101419
Redox biology 2020 Feb;30:101419
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Li R, Liu Y, Xie J, Huang X, Zhang L, Liu H, Li L
Free radical biology & medicine 2019 May 1;135:116-124
Free radical biology & medicine 2019 May 1;135:116-124
Potent and specific MTH1 inhibitors targeting gastric cancer.
Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, Ma J, Zhao L, Wang J, Jiang G, Wan X, Adam Goscinski M, Ding L, Zheng Y, Li W, Liu H, Suo Z, Zhao W
Cell death & disease 2019 Jun 4;10(6):434
Cell death & disease 2019 Jun 4;10(6):434
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Hu XN, Wang JF, Huang YQ, Wang Z, Dong FY, Ma HF, Bao ZJ
PeerJ 2018;6:e5145
PeerJ 2018;6:e5145
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Liu Y, Li R, Xie J, Hu J, Huang X, Ren F, Li L
Frontiers in aging neuroscience 2018;10:389
Frontiers in aging neuroscience 2018;10:389
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, Wang P, Su X, Liao Y, De Saeger S, Humpf HU, Wu A
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, Su C, Xia X, Song E, Song Y
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.
Lokanga RA, Senejani AG, Sweasy JB, Usdin K
PLoS genetics 2015 Apr;11(4):e1005181
PLoS genetics 2015 Apr;11(4):e1005181
X inactivation plays a major role in the gender bias in somatic expansion in a mouse model of the fragile X-related disorders: implications for the mechanism of repeat expansion.
Adihe Lokanga R, Zhao XN, Entezam A, Usdin K
Human molecular genetics 2014 Sep 15;23(18):4985-94
Human molecular genetics 2014 Sep 15;23(18):4985-94
Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.
Sriram S, Subramanian S, Juvvuna PK, McFarlane C, Salerno MS, Kambadur R, Sharma M
The Journal of biological chemistry 2014 Feb 28;289(9):5784-98
The Journal of biological chemistry 2014 Feb 28;289(9):5784-98
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15125-1-AP( OGG1 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OGG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OGG1. This antibody recognizes human,mouse,rat antigen. The OGG1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15125-1-AP(OGG1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
