Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15125-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15125-1-AP, RRID:AB_2156780
- Product name
- OGG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OGG1 antibody (Cat. #15125-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Hypertrophy of Rat Skeletal Muscle Is Associated with Increased SIRT1/Akt/mTOR/S6 and Suppressed Sestrin2/SIRT3/FOXO1 Levels.
Induction of apoptosis in Ogg1-null mouse embryonic fibroblasts by GSH depletion is independent of DNA damage.
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM2.5 from Beijing, China, in Winter.
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Potent and specific MTH1 inhibitors targeting gastric cancer.
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Heterozygosity for a hypomorphic PolĪ² mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.
X inactivation plays a major role in the gender bias in somatic expansion in a mouse model of the fragile X-related disorders: implications for the mechanism of repeat expansion.
Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Hypertrophy of Rat Skeletal Muscle Is Associated with Increased SIRT1/Akt/mTOR/S6 and Suppressed Sestrin2/SIRT3/FOXO1 Levels.
Gombos Z, Koltai E, Torma F, Bakonyi P, Kolonics A, Aczel D, Ditroi T, Nagy P, Kawamura T, Radak Z
International journal of molecular sciences 2021 Jul 15;22(14)
International journal of molecular sciences 2021 Jul 15;22(14)
Induction of apoptosis in Ogg1-null mouse embryonic fibroblasts by GSH depletion is independent of DNA damage.
Higgs EB, Godschalk R, Coltman NJ, Stewart GS, van Schooten FJ, Hodges NJ
Toxicology letters 2020 Oct 10;332:27-35
Toxicology letters 2020 Oct 10;332:27-35
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM2.5 from Beijing, China, in Winter.
Niu BY, Li WK, Li JS, Hong QH, Khodahemmati S, Gao JF, Zhou ZX
International journal of environmental research and public health 2020 Jul 6;17(13)
International journal of environmental research and public health 2020 Jul 6;17(13)
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Zhang N, Zhang Y, Wu B, You S, Sun Y
Redox biology 2020 Feb;30:101419
Redox biology 2020 Feb;30:101419
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Li R, Liu Y, Xie J, Huang X, Zhang L, Liu H, Li L
Free radical biology & medicine 2019 May 1;135:116-124
Free radical biology & medicine 2019 May 1;135:116-124
Potent and specific MTH1 inhibitors targeting gastric cancer.
Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, Ma J, Zhao L, Wang J, Jiang G, Wan X, Adam Goscinski M, Ding L, Zheng Y, Li W, Liu H, Suo Z, Zhao W
Cell death & disease 2019 Jun 4;10(6):434
Cell death & disease 2019 Jun 4;10(6):434
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Hu XN, Wang JF, Huang YQ, Wang Z, Dong FY, Ma HF, Bao ZJ
PeerJ 2018;6:e5145
PeerJ 2018;6:e5145
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Liu Y, Li R, Xie J, Hu J, Huang X, Ren F, Li L
Frontiers in aging neuroscience 2018;10:389
Frontiers in aging neuroscience 2018;10:389
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, Wang P, Su X, Liao Y, De Saeger S, Humpf HU, Wu A
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, Su C, Xia X, Song E, Song Y
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Heterozygosity for a hypomorphic PolĪ² mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.
Lokanga RA, Senejani AG, Sweasy JB, Usdin K
PLoS genetics 2015 Apr;11(4):e1005181
PLoS genetics 2015 Apr;11(4):e1005181
X inactivation plays a major role in the gender bias in somatic expansion in a mouse model of the fragile X-related disorders: implications for the mechanism of repeat expansion.
Adihe Lokanga R, Zhao XN, Entezam A, Usdin K
Human molecular genetics 2014 Sep 15;23(18):4985-94
Human molecular genetics 2014 Sep 15;23(18):4985-94
Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.
Sriram S, Subramanian S, Juvvuna PK, McFarlane C, Salerno MS, Kambadur R, Sharma M
The Journal of biological chemistry 2014 Feb 28;289(9):5784-98
The Journal of biological chemistry 2014 Feb 28;289(9):5784-98
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15125-1-AP( OGG1 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OGG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OGG1. This antibody recognizes human,mouse,rat antigen. The OGG1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15125-1-AP(OGG1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue