15494-1-AP
antibody from Proteintech Group
Targeting: RUNX1T1
AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15494-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15494-1-AP, RRID:AB_2184217
- Product name
- RUNX1T1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RUNX1T1 antibody (Cat. #15494-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HOX code-based stratification reveals RUNX1T1-HDAC reprogramming as a targetable driver of lineage plasticity across cancers.
RUNX1T1-HDAC Reprogramming of the HOX Code Signaling Drives a Targetable Pan-Cancer Lineage Plasticity.
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
Genome-wide analysis reveals porcine LIFR regulated by DNA methylation promotes the implantation process via the STAT3 signaling.
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.
Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Jiang Y, Cheng S, Zhang CY, Jin X, Li L, Shin HE, Alrefai A, Luo A, Xu Y, Kim IY, Mu P
Cancer letters 2026 Jun 28;648:218465
Cancer letters 2026 Jun 28;648:218465
RUNX1T1-HDAC Reprogramming of the HOX Code Signaling Drives a Targetable Pan-Cancer Lineage Plasticity.
Jiang Y, Cheng S, Zhang CY, Jin X, Xu Y, Kim IY, Mu P
bioRxiv : the preprint server for biology 2025 Oct 8;
bioRxiv : the preprint server for biology 2025 Oct 8;
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
Ni Y, Lin D, Shi M, Lin YY, Xue H, Dong X, Liu L, Sar F, Wu R, Morova T, Haegert A, Bell R, Pang X, Classen A, Wang Y, Chen J, Volik S, Bihan SL, Lack N, Ong C, Wang G, Zeng H, Collins C, Wang Y
bioRxiv : the preprint server for biology 2025 May 18;
bioRxiv : the preprint server for biology 2025 May 18;
Genome-wide analysis reveals porcine LIFR regulated by DNA methylation promotes the implantation process via the STAT3 signaling.
Zhou C, Huang S, Zheng S, Pius L, Liu M, Xu D
International journal of biological macromolecules 2025 Mar;295:139450
International journal of biological macromolecules 2025 Mar;295:139450
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.
Murray JE, Valli E, Milazzo G, Mayoh C, Gifford AJ, Fletcher JI, Xue C, Jayatilleke N, Salehzadeh F, Gamble LD, Rouaen JRC, Carter DR, Forgham H, Sekyere EO, Keating J, Eden G, Allan S, Alfred S, Kusuma FK, Clark A, Webber H, Russell AJ, de Weck A, Kile BT, Santulli M, De Rosa P, Fleuren EDG, Gao W, Wilkinson-White L, Low JKK, Mackay JP, Marshall GM, Hilton DJ, Giorgi FM, Koster J, Perini G, Haber M, Norris MD
Nature communications 2024 Jul 11;15(1):5585
Nature communications 2024 Jul 11;15(1):5585
Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.
Xu Y, Kusuyama J, Osana S, Matsuhashi S, Li L, Takada H, Inada H, Nagatomi R
The Journal of biological chemistry 2023 Jun;299(6):104802
The Journal of biological chemistry 2023 Jun;299(6):104802
Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
Deng K, Ren C, Liu Z, Gao X, Fan Y, Zhang G, Zhang Y, Ma ES, Wang F, You P
International journal of molecular sciences 2018 Apr 26;19(5)
International journal of molecular sciences 2018 Apr 26;19(5)
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong HS, Yanagisawa H, Niu Y, Jia GF, Wu W, Tong WM, Okamoto A, He C, Rendtlew Danielsen JM, Wang XJ, Yang YG
Cell research 2014 Dec;24(12):1403-19
Cell research 2014 Dec;24(12):1403-19
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The RUNX1T1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RUNX1T1. This antibody recognizes human, mouse antigen. The RUNX1T1 antibody has been validated for the following applications: ELISA, WB analysis.