15199-1-AP
antibody from Proteintech Group
Targeting: TMED10
p23, P24(DELTA), p24d1, p24delta1, TMP21
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15199-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15199-1-AP, RRID:AB_2204321
- Product name
- TMP21 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TMP21 antibody (Cat. #15199-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion.
Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis.
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Label-free quantitative mass spectrometry analysis of differential protein expression in the developing cochlear sensory epithelium.
A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.
Sun Y, Tao X, Han Y, Lin X, Tian R, Wang H, Chang P, Sun Q, Ge L, Zhang M
Nature cell biology 2024 Jul;26(7):1077-1092
Nature cell biology 2024 Jul;26(7):1077-1092
Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis.
Jiao M, Wang C, Tang X, Dai C, Zhang N, Fan A, Qian Z, Liu S, Zhang F, Li B, Xu Y, Tan Z, Gong F, Lu Y, Zheng F
Brain, behavior, and immunity 2024 Jul;119:539-553
Brain, behavior, and immunity 2024 Jul;119:539-553
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
Li S, Yan R, Xu J, Zhao S, Ma X, Sun Q, Zhang M, Li Y, Liu JG, Chen L, Li S, Xu K, Ge L
Cell research 2022 Feb;32(2):119-138
Cell research 2022 Feb;32(2):119-138
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
Park H, Seo SK, Sim JR, Hwang SJ, Kim YJ, Shin DH, Jang DG, Noh SH, Park PG, Ko SH, Shin MH, Choi JY, Ito Y, Kang CM, Lee JM, Lee MG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Zhang M, Liu L, Lin X, Wang Y, Li Y, Guo Q, Li S, Sun Y, Tao X, Zhang D, Lv X, Zheng L, Ge L
Cell 2020 Apr 30;181(3):637-652.e15
Cell 2020 Apr 30;181(3):637-652.e15
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q
BMC cancer 2020 Apr 15;20(1):312
BMC cancer 2020 Apr 15;20(1):312
Label-free quantitative mass spectrometry analysis of differential protein expression in the developing cochlear sensory epithelium.
Darville LNF, Sokolowski BHA
Proteome science 2018;16:15
Proteome science 2018;16:15
A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.
Sun J, Yu S, Zhang X, Capac C, Aligbe O, Daudelin T, Bonder EM, Gao N
Journal of cell science 2017 Jul 1;130(13):2159-2171
Journal of cell science 2017 Jul 1;130(13):2159-2171
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 15199-1-AP(TMED10 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using TMED10 antibody 15199-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 15199-1-AP(TMED10 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 15199-1-AP(TMED10 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue