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Protein structure
TMED10
Transmembrane p24 trafficking protein 10p23, P24(DELTA), p24d1, p24delta1, TMP21
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  15199-1-AP |
8 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C830933 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN500992 |
4 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NB100-58962 |
1 references | Polyclonal |
EL
ICC
FC
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| Boster Biological Technology | A07234 |
Polyclonal |
WB
EL
ICC
IHC
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