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- Antibody Data
- Antigen structure
- References [22]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11607-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11607-1-AP, RRID:AB_2237519
- Product name
- Cyclophilin B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Cyclophilin B antibody (Cat. #11607-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
Hub Genes PRPF19 and PPIB: Molecular Pathways and Potential Biomarkers in COPD.
LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling.
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Inhibition of Drp1-mediated mitochondrial fission by P110 ameliorates renal injury in diabetic nephropathy.
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming.
miR-199a-5p aggravates renal ischemia-reperfusion and transplant injury by targeting AKAP1 to disrupt mitochondrial dynamics.
Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3.
OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.
Isolation and short-term culturing of primary lymphatic endothelial cells from collecting lymphatics: A techniques study.
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
RP105 protects against ischemic and septic acute kidney injury via suppressing TLR4/NF-κB signaling pathways.
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations.
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate.
Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.
Proteomic methods reveal cyclophilin A function as a host restriction factor against rotavirus infection.
Synchronous detection of miRNAs, their targets and downstream proteins in transferred FFPE sections: applications in clinical and basic research.
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells.
PPIB mutations cause severe osteogenesis imperfecta.
Modulated T-complex protein 1 ζ and peptidyl-prolyl cis-trans isomerase B are two novel indicators for evaluating lymph node metastasis in colorectal cancer: Evidence from proteomics and bioinformatics.
Zhang Y, Liu C, Jin S, Xie L, Xiao Q, Yao J
Biomaterials research 2025;29:0232
Biomaterials research 2025;29:0232
Hub Genes PRPF19 and PPIB: Molecular Pathways and Potential Biomarkers in COPD.
Zhao J, Ge X, Li H, Jing G, Ma W, Fan Y, Chen J, Zhao Z, Hou J
International journal of chronic obstructive pulmonary disease 2025;20:1865-1880
International journal of chronic obstructive pulmonary disease 2025;20:1865-1880
LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling.
Rui B, Yang Y, Geng D, Kuang Z, Mu T, Liu Y, Ren B, He R, Zhang X, Zhang Y, Wang M
Journal of translational medicine 2025 Jun 11;23(1):640
Journal of translational medicine 2025 Jun 11;23(1):640
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Zhao X, Xu Y, Li S, Bai S, Zhang W, Zhang Y
Biomolecules 2025 Feb 18;15(2)
Biomolecules 2025 Feb 18;15(2)
Inhibition of Drp1-mediated mitochondrial fission by P110 ameliorates renal injury in diabetic nephropathy.
Yue R, Yan Z, Zha H, Xia Y, Huang H, Li H, Ding M, Abdullah MMH, Hu B, Shi L, Zhu J, Song Z
International immunopharmacology 2025 Apr 16;152:114342
International immunopharmacology 2025 Apr 16;152:114342
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming.
Li H, Xia Y, Zha H, Zhang Y, Shi L, Wang J, Huang H, Yue R, Hu B, Zhu J, Song Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167433
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167433
miR-199a-5p aggravates renal ischemia-reperfusion and transplant injury by targeting AKAP1 to disrupt mitochondrial dynamics.
Shi L, Zha H, Huang H, Xia Y, Li H, Huang J, Yue R, Li C, Zhu J, Song Z
American journal of physiology. Renal physiology 2024 Nov 1;327(5):F910-F929
American journal of physiology. Renal physiology 2024 Nov 1;327(5):F910-F929
Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3.
Zhang Y, Zhao X, Li S, Xu Y, Bai S, Zhang W
Animals : an open access journal from MDPI 2024 Dec 2;14(23)
Animals : an open access journal from MDPI 2024 Dec 2;14(23)
OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.
Zhao F, Zhu J, Zhang M, Luo Y, Li Y, Shi L, Huang J, Shadekejiang H, Dong S, Wu X
Cell proliferation 2023 Aug;56(8):e13418
Cell proliferation 2023 Aug;56(8):e13418
Isolation and short-term culturing of primary lymphatic endothelial cells from collecting lymphatics: A techniques study.
Jablon KL, Akerstrom VL, Li M, Braun SE, Norton CE, Castorena-Gonzalez JA
Microcirculation (New York, N.Y. : 1994) 2023 Apr;30(2-3):e12778
Microcirculation (New York, N.Y. : 1994) 2023 Apr;30(2-3):e12778
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
Shi L, Song Z, Li C, Deng F, Xia Y, Huang J, Wu X, Zhu J
Cells 2022 Dec 7;11(24)
Cells 2022 Dec 7;11(24)
RP105 protects against ischemic and septic acute kidney injury via suppressing TLR4/NF-κB signaling pathways.
Zhu J, Zhang Y, Shi L, Xia Y, Zha H, Li H, Song Z
International immunopharmacology 2022 Aug;109:108904
International immunopharmacology 2022 Aug;109:108904
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Wang Q, Luo Y, Shang W, Shi Z, Xiao G, Zhang L
Biosafety and health 2021 Jun;3(3):156-163
Biosafety and health 2021 Jun;3(3):156-163
Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations.
Wu J, Zhang W, Xia L, Feng L, Shu Z, Zhang J, Ye W, Zeng N, Zhou A
Cellular and molecular life sciences : CMLS 2019 Oct;76(19):3899-3914
Cellular and molecular life sciences : CMLS 2019 Oct;76(19):3899-3914
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate.
Besio R, Garibaldi N, Leoni L, Cipolla L, Sabbioneda S, Biggiogera M, Mottes M, Aglan M, Otaify GA, Temtamy SA, Rossi A, Forlino A
Disease models & mechanisms 2019 Jun 20;12(6)
Disease models & mechanisms 2019 Jun 20;12(6)
Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.
Chen PH, Cai L, Huffman K, Yang C, Kim J, Faubert B, Boroughs L, Ko B, Sudderth J, McMillan EA, Girard L, Chen D, Peyton M, Shields MD, Yao B, Shames DS, Kim HS, Timmons B, Sekine I, Britt R, Weber S, Byers LA, Heymach JV, Chen J, White MA, Minna JD, Xiao G, DeBerardinis RJ
Molecular cell 2019 Dec 5;76(5):838-851.e5
Molecular cell 2019 Dec 5;76(5):838-851.e5
Proteomic methods reveal cyclophilin A function as a host restriction factor against rotavirus infection.
He H, Mou Z, Li W, Fei L, Tang Y, Zhang J, Yan P, Chen Z, Yang X, Shen Z, Li J, Wu Y
Proteomics 2013 Apr;13(7):1121-32
Proteomics 2013 Apr;13(7):1121-32
Synchronous detection of miRNAs, their targets and downstream proteins in transferred FFPE sections: applications in clinical and basic research.
Zhao JY, Liu CQ, Zhao HN, Ding YF, Bi T, Wang B, Lin XC, Guo G, Cui SY
Methods (San Diego, Calif.) 2012 Oct;58(2):156-63
Methods (San Diego, Calif.) 2012 Oct;58(2):156-63
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.
Pyott SM, Schwarze U, Christiansen HE, Pepin MG, Leistritz DF, Dineen R, Harris C, Burton BK, Angle B, Kim K, Sussman MD, Weis M, Eyre DR, Russell DW, McCarthy KJ, Steiner RD, Byers PH
Human molecular genetics 2011 Apr 15;20(8):1595-609
Human molecular genetics 2011 Apr 15;20(8):1595-609
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells.
Watanabe A, Yoneda M, Ikeda F, Terao-Muto Y, Sato H, Kai C
Journal of virology 2010 May;84(9):4183-93
Journal of virology 2010 May;84(9):4183-93
PPIB mutations cause severe osteogenesis imperfecta.
van Dijk FS, Nesbitt IM, Zwikstra EH, Nikkels PG, Piersma SR, Fratantoni SA, Jimenez CR, Huizer M, Morsman AC, Cobben JM, van Roij MH, Elting MW, Verbeke JI, Wijnaendts LC, Shaw NJ, Högler W, McKeown C, Sistermans EA, Dalton A, Meijers-Heijboer H, Pals G
American journal of human genetics 2009 Oct;85(4):521-7
American journal of human genetics 2009 Oct;85(4):521-7
Modulated T-complex protein 1 ζ and peptidyl-prolyl cis-trans isomerase B are two novel indicators for evaluating lymph node metastasis in colorectal cancer: Evidence from proteomics and bioinformatics.
Yue F, Wang LS, Xia L, Wang XL, Feng B, Lu AG, Chen GQ, Zheng MH
Proteomics. Clinical applications 2009 Oct;3(10):1225-35
Proteomics. Clinical applications 2009 Oct;3(10):1225-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 11607-1-AP(PPIB antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 11607-1-AP(PPIB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cyclophilin B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cyclophilin B. This antibody recognizes human, mouse antigen. The Cyclophilin B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
