BS8215

antibody from Bioworld Technology, Inc
Targeting: SKAP2 RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R
Provider product page for BS8215
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8215 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SKAP2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SKAP2.
Description
Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SKAP2 protein structure - BS8215 shown in red.