SKAP2

gene product
RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R
The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
170 antibodies from 25 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
4 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
5 antibodies
LifeSpan BioSciences, Inc.
21 antibodies
antibodies-online
58 antibodies
NovoPro Bioscience Inc.
2 antibodies
Aviva Systems Biology
4 antibodies
OriGene
3 antibodies
GeneTex
2 antibodies
Proteintech Group
1 antibody
Biorbyt
7 antibodies
Bioworld Technology, Inc
1 antibody
Abnova Corporation
4 antibodies
Signalway Antibody LLC
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Abgent
1 antibody
Acris Antibodies GmbH
1 antibody
Arigo
1 antibody
United States Biological
37 antibodies
MyBioSource
6 antibodies
ProSci
2 antibodies
RabMAbs
1 antibody
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies