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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- ABIN1003211 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Stromal Interaction Molecule 1 (STIM1) antibody
- Antibody type
- Polyclonal
- Antigen
- STIM1 antibody was raised in rabbits against a 24 amino acid peptide from near the carboxy terminus of human STIM1.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells.
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels.
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Luik RM, Lewis RS
Trends in molecular medicine 2007 Mar;13(3):103-7
Trends in molecular medicine 2007 Mar;13(3):103-7
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A
Nature 2006 May 11;441(7090):179-85
Nature 2006 May 11;441(7090):179-85
STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels.
Spassova MA, Soboloff J, He LP, Xu W, Dziadek MA, Gill DL
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 14;103(11):4040-5
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 14;103(11):4040-5
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, Stauderman KA, Cahalan MD
Nature 2005 Oct 6;437(7060):902-5
Nature 2005 Oct 6;437(7060):902-5
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