Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB2664P - Provider product page
- Provider
- R&D Systems
- Product name
- Human LAIR1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human LAIR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human LAIR2 or recombinant mouse LAIR1 is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q6GTX8
- Isotype
- IgG
- Antibody clone number
- 342219
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Survival of human circulating antigen-induced plasma cells is supported by plasma cell-niche cytokines and T follicular helper lymphocytes.
EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation.
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Ramos-Amaya A, Rodríguez-Bayona B, López-Blanco R, Andújar E, Pérez-Alegre M, Campos-Caro A, Brieva JA
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 1;194(3):1031-8
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 1;194(3):1031-8
EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.
White RE, Rämer PC, Naresh KN, Meixlsperger S, Pinaud L, Rooney C, Savoldo B, Coutinho R, Bödör C, Gribben J, Ibrahim HA, Bower M, Nourse JP, Gandhi MK, Middeldorp J, Cader FZ, Murray P, Münz C, Allday MJ
The Journal of clinical investigation 2012 Apr;122(4):1487-502
The Journal of clinical investigation 2012 Apr;122(4):1487-502
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation.
Rodríguez-Bayona B, Ramos-Amaya A, Brieva JA
Immunology letters 2011 Jan 30;134(2):122-8
Immunology letters 2011 Jan 30;134(2):122-8
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Llinàs L, Lázaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P
Immunology letters 2011 Jan 30;134(2):113-21
Immunology letters 2011 Jan 30;134(2):113-21
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mouse Anti-Human LAIR1 PE-conjugated Monoclonal Antibody (Catalog # FAB2664P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.