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LearnTissue expression
Cell line expression
Protein structure
LAIR1
Leukocyte associated immunoglobulin like receptor 1CD305
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Proteintech Group |  67220-1-Ig |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Cell Signaling Technology, Inc | 60061 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| Atlas Antibodies | HPA011155 |
3 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C197596 |
Monoclonal |
WB
EL
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| Novus Biologicals | MAB2664 |
2 references | Monoclonal |
WB
FC
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