Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13003-2-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13003-2-AP, RRID:AB_2304122
- Product name
- UBD antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBD antibody (Cat. #13003-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ubiquitin D Correlates with Disease Severity and T Cell Infiltration in Cholestasis: Evidence from Integrated Bioinformatics and Experimental Analyses.
Exploration of the mechanism by which Ubiquitin-like protein UBD promotes malignant progression of breast cancer.
Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis.
Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer.
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
B-cell lymphoma-extra large expression correlated with protein kinase RNA-like ER kinase and ubiquitination signals in the type 1 diabetes mouse model.
FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma.
The pivotal role of ZNF384: driving the malignant behavior of serous ovarian cancer cells via the LIN28B/UBD axis.
Roles of Neuronal Protein Kinase Cε on Endoplasmic Reticulum Stress and Autophagic Formation in Diabetic Neuropathy.
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
UBD participates in neutrophilic asthma by promoting the activation of IL-17 signaling.
c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium.
Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.
Onset of hepatocarcinogen-specific cell proliferation and cell cycle aberration during the early stage of repeated hepatocarcinogen administration in rats.
Aberrant cell cycle regulation in rat liver cells induced by post-initiation treatment with hepatocarcinogens/hepatocarcinogenic tumor promoters.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Disruption of spindle checkpoint function ahead of facilitation of cell proliferation by repeated administration of hepatocarcinogens in rats.
Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats.
Fluctuations in cell proliferation, apoptosis, and cell cycle regulation at the early stage of tumor promotion in rat two-stage carcinogenesis models.
Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats.
Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.
Wang H, Zhang J, Huang X, Peng S
International journal of medical sciences 2026;23(1):350-362
International journal of medical sciences 2026;23(1):350-362
Exploration of the mechanism by which Ubiquitin-like protein UBD promotes malignant progression of breast cancer.
Ma L, Xie B, Zhang R, Deng H, Tang B, Zhu J, Zhang Z, Ma X, Wang S, Li L
Medical oncology (Northwood, London, England) 2026 Apr 27;43(6)
Medical oncology (Northwood, London, England) 2026 Apr 27;43(6)
Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis.
Liu L, Che B, Zhang W, Du D, Zhang D, Li J, Chen Z, Yu X, Ye M, Wang W, Li Z, Xie F, Wang Q, Chen L, Shao J
Cell death & disease 2025 May 15;16(1):385
Cell death & disease 2025 May 15;16(1):385
Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer.
Zhao A, Zhou S, Yang X, Lu H, Zou D, Zhang X, Liu L
Discover oncology 2025 Mar 12;16(1):309
Discover oncology 2025 Mar 12;16(1):309
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
Dong J, Wu Y, Che J, He Z, Zhang J
Cancer & metabolism 2025 Jun 23;13(1):33
Cancer & metabolism 2025 Jun 23;13(1):33
B-cell lymphoma-extra large expression correlated with protein kinase RNA-like ER kinase and ubiquitination signals in the type 1 diabetes mouse model.
Kan YY, Chang YS, Chao TN, Hsieh YL
Pain reports 2025 Dec;10(6):e1356
Pain reports 2025 Dec;10(6):e1356
FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma.
Wang Q, Tan W, Zhang Z, Chen Q, Xie Z, Yang L, Tang C, Zhuang H, Wang B, Jiang J, Ma X, Wang W, Hua Y, Shang C, Chen Y
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1529-1545
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1529-1545
The pivotal role of ZNF384: driving the malignant behavior of serous ovarian cancer cells via the LIN28B/UBD axis.
Yang Y, He R, Li D, Mu T, Kuang Z, Wang M
Cell biology and toxicology 2024 Nov 19;40(1):100
Cell biology and toxicology 2024 Nov 19;40(1):100
Roles of Neuronal Protein Kinase Cε on Endoplasmic Reticulum Stress and Autophagic Formation in Diabetic Neuropathy.
Kan YY, Chang YS, Liao WC, Chao TN, Hsieh YL
Molecular neurobiology 2024 May;61(5):2481-2495
Molecular neurobiology 2024 May;61(5):2481-2495
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Wu T, Du M, Zeng L, Wang H, Li X
Environmental toxicology 2024 Dec;39(12):5250-5263
Environmental toxicology 2024 Dec;39(12):5250-5263
UBD participates in neutrophilic asthma by promoting the activation of IL-17 signaling.
Liu Y, Cheng K, Sun M, Ding C, Li T, Jia Y, Wang C, Zhu X, Song X, Jia R, Wang Q, Zhang Y, Sun X
International journal of biological macromolecules 2024 Apr;264(Pt 1):130581
International journal of biological macromolecules 2024 Apr;264(Pt 1):130581
c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium.
Sehgal A, Kobayashi A, Donaldson DS, Mabbott NA
Immunobiology 2017 Feb;222(2):316-326
Immunobiology 2017 Feb;222(2):316-326
Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.
Brozzi F, Gerlo S, Grieco FA, Juusola M, Balhuizen A, Lievens S, Gysemans C, Bugliani M, Mathieu C, Marchetti P, Tavernier J, Eizirik DL
The Journal of biological chemistry 2016 Jun 3;291(23):12040-56
The Journal of biological chemistry 2016 Jun 3;291(23):12040-56
Onset of hepatocarcinogen-specific cell proliferation and cell cycle aberration during the early stage of repeated hepatocarcinogen administration in rats.
Kimura M, Abe H, Mizukami S, Tanaka T, Itahashi M, Onda N, Yoshida T, Shibutani M
Journal of applied toxicology : JAT 2016 Feb;36(2):223-37
Journal of applied toxicology : JAT 2016 Feb;36(2):223-37
Aberrant cell cycle regulation in rat liver cells induced by post-initiation treatment with hepatocarcinogens/hepatocarcinogenic tumor promoters.
Kimura M, Mizukami S, Watanabe Y, Onda N, Yoshida T, Shibutani M
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2016 Aug;68(7):399-408
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2016 Aug;68(7):399-408
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Liu X, Chen L, Ge J, Yan C, Huang Z, Hu J, Wen C, Li M, Huang D, Qiu Y, Hao H, Yuan R, Lei J, Yu X, Shao J
Cancer research 2016 Aug 15;76(16):4897-907
Cancer research 2016 Aug 15;76(16):4897-907
Disruption of spindle checkpoint function ahead of facilitation of cell proliferation by repeated administration of hepatocarcinogens in rats.
Kimura M, Mizukami S, Watanabe Y, Hasegawa-Baba Y, Onda N, Yoshida T, Shibutani M
The Journal of toxicological sciences 2015 Dec;40(6):855-71
The Journal of toxicological sciences 2015 Dec;40(6):855-71
Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats.
Taniai E, Yafune A, Nakajima M, Hayashi SM, Nakane F, Itahashi M, Shibutani M
Toxicology letters 2014 Jan 3;224(1):64-72
Toxicology letters 2014 Jan 3;224(1):64-72
Fluctuations in cell proliferation, apoptosis, and cell cycle regulation at the early stage of tumor promotion in rat two-stage carcinogenesis models.
Taniai E, Yafune A, Kimura M, Morita R, Nakane F, Suzuki K, Mitsumori K, Shibutani M
The Journal of toxicological sciences 2012;37(6):1113-26
The Journal of toxicological sciences 2012;37(6):1113-26
Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats.
Taniai E, Yafune A, Hayashi H, Itahashi M, Hara-Kudo Y, Suzuki K, Mitsumori K, Shibutani M
The Journal of toxicological sciences 2012;37(6):1093-111
The Journal of toxicological sciences 2012;37(6):1093-111
Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.
Kobayashi A, Donaldson DS, Kanaya T, Fukuda S, Baillie JK, Freeman TC, Ohno H, Williams IR, Mabbott NA
DNA research : an international journal for rapid publication of reports on genes and genomes 2012 Oct;19(5):407-22
DNA research : an international journal for rapid publication of reports on genes and genomes 2012 Oct;19(5):407-22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human stomach tissue were subjected to SDS PAGE followed by western blot with 13003-2-AP(UBD antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The UBD antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human UBD. This antibody recognizes human, mouse, rat antigen. The UBD antibody has been validated for the following applications: ELISA, WB, IHC analysis.