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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- MAB7098 - Provider product page
- Provider
- R&D Systems
- Product name
- Human HLA Class I Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects the human major histocompatibility complex (MHC) class I, HLA-A, B, and C. Recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both the HLA molecule and beta 2-Microglobulin.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- W6/32
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord.
Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.
Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance.
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens.
Li J, Xu SQ, Zhao YM, Yu S, Ge LH, Xu BH
Molecular medicine reports 2018 Dec;18(6):4969-4977
Molecular medicine reports 2018 Dec;18(6):4969-4977
Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.
Charpak-Amikam Y, Kubsch T, Seidel E, Oiknine-Djian E, Cavaletto N, Yamin R, Schmiedel D, Wolf D, Gribaudo G, Messerle M, Cicin-Sain L, Mandelboim O
Scientific reports 2017 Aug 17;7(1):8661
Scientific reports 2017 Aug 17;7(1):8661
Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance.
Loubaki L, Chabot D, Bazin R
Cytokine 2015 Feb;71(2):181-7
Cytokine 2015 Feb;71(2):181-7
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbé C, Caillat-Zucman S
PLoS pathogens 2012 Jan;8(1):e1002486
PLoS pathogens 2012 Jan;8(1):e1002486
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens.
Parham P, Barnstable CJ, Bodmer WF
Journal of immunology (Baltimore, Md. : 1950) 1979 Jul;123(1):342-9
Journal of immunology (Baltimore, Md. : 1950) 1979 Jul;123(1):342-9
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of HLA Class I in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human HLA Class I Monoclonal Antibody (Catalog # MAB7098, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).
