Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-81642 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-81642, RRID:AB_1147221
- Product name
- Rabbit Polyclonal TDP1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan.
Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Meisenberg C, Gilbert DC, Chalmers A, Haley V, Gollins S, Ward SE, El-Khamisy SF
Molecular cancer therapeutics 2015 Feb;14(2):575-85
Molecular cancer therapeutics 2015 Feb;14(2):575-85
Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Perego P, Cossa G, Tinelli S, Corna E, Carenini N, Gatti L, De Cesare M, Ciusani E, Zunino F, Luison E, Canevari S, Zaffaroni N, Beretta GL
Biochemical pharmacology 2012 Jan 1;83(1):27-36
Biochemical pharmacology 2012 Jan 1;83(1):27-36
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TDP1 Antibody [NB100-81642] - Detection of Human TDP1 on HeLa whole cell lysate using NB100-81642. TDP1 was also immunoprecipitated by rabbit anti-TDP1 antibody NB100-81643.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TDP1 Antibody [NB100-81642] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- TDP1 used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB