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Western blot
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- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Other assay [1]
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- Product number
- PA5-62137 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- eIF3c Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: NELMDILFAN PNIFVGENIL EESENLHNAD QPLRVRGCIL TLVERMDEEF TKIMQNTDPH SQEYVEHLKD EAQVCAIIER VQRYLEEKGT TE Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.4 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Knockdown of EIF3C promotes human U-2OS cells apoptosis through increased CASP3/7 and Chk1/2 by upregulating SAPK/JNK.
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway.
Gao W, Hu Y, Zhang Z, Du G, Yin L, Yin Z
OncoTargets and therapy 2019;12:1225-1235
OncoTargets and therapy 2019;12:1225-1235
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway.
Zhao W, Li X, Wang J, Wang C, Jia Y, Yuan S, Huang Y, Shi Y, Tong Z
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 30;23:4182-4191
Medical science monitor : international medical journal of experimental and clinical research 2017 Aug 30;23:4182-4191
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 1 Expression of EIF3C and Ki-67 in breast cancer tissues. ( A, C, E ) EIF3C antigen expression in breast cancer tissues. Low expression in A, moderate expression in C and high expression in E . ( B, D, F ) Positive nuclear Ki-67 staining in breast cancer tissues. Low expression in B , moderate expression in D and high expression in F . (SP, magnification, 400x).
