Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 11317-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11317-1-AP, RRID:AB_2118133
- Product name
- HEXA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HEXA antibody (Cat. #11317-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SNX8 enables lysosome reformation and reverses lysosomal storage disorder.
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients.
VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
The phagosomal proteome in interferon-gamma-activated macrophages.
Li X, Xiang C, Zhu S, Guo J, Liu C, Wang A, Cao J, Lu Y, Neculai D, Xu P, Feng XH
Nature communications 2024 Mar 22;15(1):2553
Nature communications 2024 Mar 22;15(1):2553
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
He Y, Kaya I, Shariatgorji R, Lundkvist J, Wahlberg LU, Nilsson A, Mamula D, Kehr J, Zareba-Paslawska J, Biverstål H, Chergui K, Zhang X, Andren PE, Svenningsson P
Nature communications 2023 Sep 19;14(1):5804
Nature communications 2023 Sep 19;14(1):5804
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Lin Y, Shi Q, Yang G, Shi F, Zhou Y, Wang T, Xu P, Li P, Liu Z, Sun H, Zhao Z, Ding K, Wang Z, Feng H, Yu B, Fang P, Wang J
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 14;120(7):e2213670120
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 14;120(7):e2213670120
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924
Nature communications 2022 Oct 7;13(1):5924
Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients.
Jia M, Zhang W, Zhu J, Huang C, Zhou J, Lian J, Wang Y, Teng H, Huang Z
Frontiers in oncology 2021;11:685893
Frontiers in oncology 2021;11:685893
VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 15;183(2):1413-8
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 15;183(2):1413-8
The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity 2009 Jan 16;30(1):143-54
Immunity 2009 Jan 16;30(1):143-54
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 11317-1-AP(HEXA antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 11317-1-AP(HEXA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HEXA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HEXA. This antibody recognizes human, mouse, rat antigen. The HEXA antibody has been validated for the following applications: ELISA, WB, IHC analysis.