HEXA

gene product
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
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465 antibodies from 28 providers.

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antibodies-online
176 antibodies
Novus Biologicals
38 antibodies
Biorbyt
23 antibodies
GeneTex
5 antibodies
NovoPro Bioscience Inc.
6 antibodies
Abgent
5 antibodies
Acris Antibodies GmbH
9 antibodies
Atlas Antibodies
1 antibody
OriGene
6 antibodies
LifeSpan BioSciences, Inc.
89 antibodies
Proteintech Group
2 antibodies
Aviva Systems Biology
3 antibodies
ProSci
2 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
8 antibodies
Boster Biological Technology
2 antibodies
R&D Systems
3 antibodies
NSJ Bioreagents
2 antibodies
Invitrogen Antibodies
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
St John's Laboratory
3 antibodies
RabMAbs
1 antibody
MyBioSource
6 antibodies
Creative Biolabs
12 antibodies
Creative Diagnostics
4 antibodies
United States Biological
50 antibodies
Sigma-Aldrich
3 antibodies