HEXA

gene product
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009]
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334 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
46 antibodies
Biorbyt
14 antibodies
antibodies-online
78 antibodies
GeneTex
5 antibodies
NovoPro Bioscience Inc.
6 antibodies
Abgent
5 antibodies
Acris Antibodies GmbH
9 antibodies
OriGene
7 antibodies
Proteintech Group
2 antibodies
Aviva Systems Biology
3 antibodies
LifeSpan BioSciences, Inc.
68 antibodies
ProSci
2 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
8 antibodies
Boster Biological Technology
2 antibodies
R&D Systems
3 antibodies
NSJ Bioreagents
2 antibodies
Invitrogen Antibodies
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
St John's Laboratory
3 antibodies
RabMAbs
1 antibody
MyBioSource
6 antibodies
Atlas Antibodies
1 antibody
Creative Diagnostics
3 antibodies
United States Biological
50 antibodies
Sigma-Aldrich
3 antibodies
Creative Biolabs
1 antibody