FNab03842

antibody from FineTest Biotech

Targeting: HEXA

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab03842 - Provider product page
Provider: FineTest Biotech
Product name: HEXA antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: hexosaminidase A (alpha polypeptide )
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

HEXA protein structure - FNab03842 shown in red.