BS7654

antibody from Bioworld Technology, Inc
Targeting: HEXA
Provider product page for BS7654
Western blot
Immunohistochemistry

Antibody data

Product number
BS7654 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HEXA polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HEXA.
Description
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HEXA protein structure - BS7654 shown in red.