Ab129563

antibody from Aladdin Scientific

Targeting: STING1 ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173

Antibody data

Submit

Validation data

Product number: Ab129563 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant STING Antibody
Antibody type: Recombinant
Description: Rabbit anti Human STING Antibody, Recombinant, could be used for WB, IHC and so on.Application:WB: 1/500 Ð 1/2000IHC: 1/50-/100Protein FunctionFacilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Reactivity: Human, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 273-377
Vial size: 100_l,10_l,1ml,50_l
Concentration: 0,4 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

STING1 protein structure - Ab129563 shown in red.