Tissue expression
Cell line expression
Protein structure
STING1
Stimulator of interferon response cGAMP interactor 1ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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Proteintech Group | 19851-1-AP | 79 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | PA5-23381 | 3 references | Polyclonal |
WB
EL
ICC
IHC
FC
OA |
|
Novus Biologicals | NBP2-24683 | 15 references | Polyclonal |
WB
ICC
IHC
FC |
|
R&D Systems | MAB7169 | 12 references | Monoclonal |
WB
ICC
FC
|
|
NovoPro Bioscience Inc. | 116105 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider