LOXL1

gene product
LOL, LOXL
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016]
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Abnova Corporation
4 antibodies
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5 antibodies
antibodies-online
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Invitrogen Antibodies
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NSJ Bioreagents
1 antibody
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2 antibodies
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3 antibodies
Atlas Antibodies
2 antibodies
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ProSci
1 antibody
St John's Laboratory
1 antibody
Abbexa
7 antibodies
Creative Diagnostics
1 antibody
Abgent
2 antibodies
Leading Biology
2 antibodies
Sigma-Aldrich
2 antibodies