Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- PB9438 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Serotonin transporter/SLC6A4 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for SEROTONIN TRANSPORTER/SLC6A4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. SEROTONIN TRANSPORTER/SLC6A4 information: Molecular Weight: 70325 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin; Tissue Specificity: Expressed in platelets (at protein level).
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Regulatory Effect of Electroacupuncture on Hypothalamic Serotonin and its Receptor in Rats with Cerebral Ischemia.
Effect of sepsis on the action potential and cardiac serotonin response in rats.
Chronic Unpredictable Mild Stress Causing Cardiac and Thoracic Spinal Cord Electrophysiological Abnormalities May Be Associated with Increased Cardiac Expression of Serotonin and Growth-Associated Protein-43 in Rats.
Ma T, Li C, Nie Z, Miao H, Wu F
Current neurovascular research 2023;20(2):237-243
Current neurovascular research 2023;20(2):237-243
Effect of sepsis on the action potential and cardiac serotonin response in rats.
Liu ZJ, Liu H, Wu C, Xue K
Experimental and therapeutic medicine 2019 Sep;18(3):2207-2212
Experimental and therapeutic medicine 2019 Sep;18(3):2207-2212
Chronic Unpredictable Mild Stress Causing Cardiac and Thoracic Spinal Cord Electrophysiological Abnormalities May Be Associated with Increased Cardiac Expression of Serotonin and Growth-Associated Protein-43 in Rats.
Liu Z, Liu H, Zeng ZH
BioMed research international 2018;2018:8697913
BioMed research international 2018;2018:8697913
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- IHC analysis of SLC6A4 using anti-SLC6A4 antibody (PB9438). SLC6A4 was detected in paraffin-embedded section of rat brain tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/ml rabbit anti-SLC6A4 Antibody (PB9438) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
- Additional image