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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 16888-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16888-1-AP, RRID:AB_2266733
- Product name
- MTCH2 antibody
- Antibody type
- Polyclonal
- Description
- MTCH2 antibody (Cat. #16888-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Serine palmitoyltransferase assembles at ER-mitochondria contact sites.
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma.
MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism.
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
miR-135b coordinates progression of ErbB2-driven mammary carcinomas through suppression of MID1 and MTCH2.
Aaltonen MJ, Alecu I, König T, Bennett SA, Shoubridge EA
Life science alliance 2022 Feb;5(2)
Life science alliance 2022 Feb;5(2)
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
Labbé K, Mookerjee S, Le Vasseur M, Gibbs E, Lerner C, Nunnari J
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
Wang YJ, Yang B, Lai Q, Shi JF, Peng JY, Zhang Y, Hu KS, Li YQ, Peng JW, Yang ZZ, Li YT, Pan Y, Koeffler HP, Liao JY, Yin D
RNA biology 2021 Jan;18(1):131-143
RNA biology 2021 Jan;18(1):131-143
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma.
Yuan Q, Yang W, Zhang S, Li T, Zuo M, Zhou X, Li J, Li M, Xia X, Chen M, Liu Y
Molecular medicine (Cambridge, Mass.) 2021 Jan 28;27(1):7
Molecular medicine (Cambridge, Mass.) 2021 Jan 28;27(1):7
MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism.
Jiang Q, Sun B, Liu Q, Cai M, Wu R, Wang F, Yao Y, Wang Y, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2971-2981
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):2971-2981
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
Zhang T, Hu Y, Wang T, Cai P
International journal of molecular medicine 2017 Jul;40(1):21-30
International journal of molecular medicine 2017 Jul;40(1):21-30
miR-135b coordinates progression of ErbB2-driven mammary carcinomas through suppression of MID1 and MTCH2.
Arigoni M, Barutello G, Riccardo F, Ercole E, Cantarella D, Orso F, Conti L, Lanzardo S, Taverna D, Merighi I, Calogero RA, Cavallo F, Quaglino E
The American journal of pathology 2013 Jun;182(6):2058-70
The American journal of pathology 2013 Jun;182(6):2058-70
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16888-1-AP(MTCH2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MTCH2 (IP:16888-1-AP, 3ug; Detection:16888-1-AP 1:1000) with HepG2 cells lysate 4000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16888-1-AP(MTCH2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MTCH2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MTCH2. This antibody recognizes human,mouse,rat antigen. The MTCH2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
