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- References [230]
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- Product number
- 11263-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11263-1-AP, RRID:AB_2167545
- Product name
- OCT4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OCT4 antibody (Cat. #11263-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
The involvement of epidermal growth factor receptor/protein kinase B signaling in the tumor intrinsic PD-L1-induced malignant potential of oral squamous cell carcinoma.
Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis.
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Generation of homozygous and heterozygous REEP1 knockout induced pluripotent stem cell lines by CRISPR/Cas9 gene editing.
Exosomal circ50547 as a potential marker and promotor of gastric cancer progression via miR-217/HNF1B axis.
Induction of mesenchymal stem cell (MSC) differentiation from iPS cells using MSC medium.
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression.
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers.
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Selective activation of TGFβ signaling by P. gingivalis-mediated upregulation of GARP aggravates esophageal squamous cell carcinoma.
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
Inhibition of Na+/H+ exchanger (NHE) 7 by 5-(N-ethyl-N-isopropyl)-Amiloride displays anti-cancer activity in non-small cell lung cancer by disrupting cancer stem cell activity and downregulating PD-L1 expression.
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability.
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Wnt10a downregulation contributes to MEHP-induced disruption of self-renewal and differentiation balance and proliferation inhibition in GC-1 cells: Insights from multiple transcriptomic profiling.
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study.
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
The neonatal southern white rhinoceros ovary contains oogonia in germ cell nests.
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Generation of a human embryonic stem cell line (SKLRMe004-A) carrying NKX2.5-EGFP and TBX5-Tdtomato dual fluorescent reporters.
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Generation of a heterozygous and a homozygous CSF1R knockout line from iPSC using CRISPR/Cas9.
Human amniotic mesenchymal stem cell-conditioned medium inhibited LPS-induced cell injury and inflammation by modulating CD14/TLR4-mediated signaling pathway in monocytes.
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2.
SLC1A5 regulates cell proliferation and self-renewal through β-catenin pathway mediated by redox signaling in arsenic-treated uroepithelial cells.
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway.
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes.
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
Isolation of female germline stem cells from neonatal piglet ovarian tissue and differentiation into oocyte-like cells.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway.
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Hepatitis B Virus Pregenomic RNA Reflecting Viral Replication in Distal Non-tumor Tissues as a Determinant of the Stemness and Recurrence of Hepatocellular Carcinoma.
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Cancer-associated fibroblasts promote the stemness and progression of renal cell carcinoma via exosomal miR-181d-5p.
Zuogui pills maintain the stemness of oogonial stem cells and alleviate cyclophosphamide-induced ovarian aging through Notch signaling pathway.
Bisphenol A induces apoptosis in response to DNA damage through c-Abl/YAP(Y357)/ p73 pathway in P19 embryonal carcinoma stem cells.
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
Addressing Doxorubicin Resistance in Bone Sarcomas Using Novel Drug-Resistant Models.
Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Generation of a human extended pluripotent stem cell line (SKLRMe002-A) carrying a doxycycline-inducible Cas9 expression cassette.
Generation of an induced pluripotent stem cell line from a patient with Angelman syndrome carrying UBE3A mutation.
Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession.
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus.
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Disturbance in transcriptomic profile, proliferation and multipotency in human mesenchymal stem cells caused by hexafluoropropylene oxides.
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis.
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop.
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
Generation of two SPAST knockout human induced pluripotent stem cell lines to create a model for Hereditary Spastic Paraplegia type 4.
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling.
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
An iPS cell line SDUBMSi0011-A from a multiple epiphyseal dysplasia patient carrying c. 1076T > G mutation in the SMOC2 gene.
Generation of two induced pluripotent stem cell lines from patients with X-linked Alport syndrome.
Generation of an induced pluripotent stem cell line SDUBMSi005-A from a patient with double primary gastric and colon carcinoma.
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Establishment of patient-specific induced pluripotent stem cell line SDUBMSi009-A from a patient with X-linked Lowe syndrome.
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Graphene Quantum Dots Disrupt Embryonic Stem Cell Differentiation by Interfering with the Methylation Level of Sox2.
p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response.
EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis.
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Effects of shikonin on the development of ovarian follicles and female germline stem cells.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy.
Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells.
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
Generation and characterization of an integration-free iPSC line SDUBMSi006-A from a patient with Alport syndrome caused by COL4A3 gene mutations.
Comparative Transcriptional Profiling of Motor Neuron Disorder-Associated Genes in Various Human Cell Culture Models.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
CCL21/CCR7 interaction promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3 signaling pathway.
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
A Combined Systemic Strategy for Overcoming Cisplatin Resistance in Head and Neck Cancer: From Target Identification to Drug Discovery.
Generation of a human induced pluripotent stem cell line (SDUBMSi001-A) from a hereditary spastic paraplegia patient carrying kif1a c.773C>T missense mutation.
Generation of patient-specific pluripotent induced stem cell line SDUBMSI002-A from a patient with X-linked mental retardation syndrome.
miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8.
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Generation of the CRISPR/Cas9-mediated KIF1C knock-out human iPSC line HIHRSi003-A-1.
MicroRNA‑487b‑3p inhibits osteosarcoma chemoresistance and metastasis by targeting ALDH1A3.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Limbal niche cells can reduce the angiogenic potential of cultivated oral mucosal epithelial cells.
Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Napabucasin Attenuates Resistance of Breast Cancer Cells to Tamoxifen by Reducing Stem Cell-Like Properties.
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation.
In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.
Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus.
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells.
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation.
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Integration-free reprogramming of human umbilical arterial endothelial cells into induced pluripotent stem cells IHSTMi001-A.
Disulfiram/copper targets stem cell-like ALDH(+) population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Bufalin Inhibits Cellular Proliferation and Cancer Stem Cell-Like Phenotypes via Upregulation of MiR-203 in Glioma.
NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes.
Soluble expression of recomb inant cMyc, Klf4, Oct4, and Sox2 proteins in bacteria and transduction into living cells.
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice.
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
Silencing of Btbd7 Inhibited Epithelial-Mesenchymal Transition and Chemoresistance in CD133(+) Lung Carcinoma A549 Cells.
Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells.
Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3β-involved Wnt/β-catenin pathway.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
NANOG overexpression and its correlation with stem cell and differentiation markers in meningiomas of different WHO grades.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas.
Enhanced tenogenic differentiation and tendon-like tissue formation by CHIP overexpression in tendon-derived stem cells.
CD44+ cancer cell-induced metastasis: A feasible neck metastasis model.
miR-612 suppresses stem cell-like property of hepatocellular carcinoma cells by modulating Sp1/Nanog signaling.
A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
Specific detection of OCT4 isoforms in inflammatory bowel disease.
The Expression of Markers Related to Ovarian Germline Stem Cells in the Mouse Ovarian Surface Epithelium and the Correlation with Notch Signaling Pathway.
Hyperglycemic Stress Impairs the Stemness Capacity of Kidney Stem Cells in Rats.
Silencing JARID1B suppresses oncogenicity, stemness and increases radiation sensitivity in human oral carcinoma.
Vacuolar ATPase in phagosome-lysosome fusion.
Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells.
Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.
MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1.
Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition.
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
Hepatitis B virus X protein upregulates Lin28A/Lin28B through Sp-1/c-Myc to enhance the proliferation of hepatoma cells.
Correlation of ALDH1, CD44, OCT4 and SOX2 in tongue squamous cell carcinoma and their association with disease progression and prognosis.
Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer.
Expression of Oct-4, SOX-2, and MYC in dental papilla cells and dental follicle cells during in-vivo tooth development and in-vitro co-culture.
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.
Wang L, Zhang L, Zhao L, Shao S, Ning Q, Jing X, Zhang Y, Zhao F, Liu X, Gu S, Zhao X, Luo M
International journal of biological sciences 2024;20(2):446-463
International journal of biological sciences 2024;20(2):446-463
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
Lu Y, Zhao X, Yuan M, Zhao M, Liu K, Zhang M, Qiu X, Yu X, Liu X, Wei D, Xie J, Cheng Z
Journal of Cancer 2024;15(9):2475-2485
Journal of Cancer 2024;15(9):2475-2485
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
Fan G, Yan Q, Chen Y, Han M, Wu Z, Ruan S, Zhuang H, Gou Q, Hou B
American journal of cancer research 2024;14(2):709-726
American journal of cancer research 2024;14(2):709-726
The involvement of epidermal growth factor receptor/protein kinase B signaling in the tumor intrinsic PD-L1-induced malignant potential of oral squamous cell carcinoma.
Sasabe E, Tomomura A, Yamamoto T
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2024 May;53(5):310-320
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2024 May;53(5):310-320
Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis.
Luo X, Wang J, Chen Y, Zhou X, Shao Z, Liu K, Shang Z
Journal of pineal research 2024 Mar;76(2):e12940
Journal of pineal research 2024 Mar;76(2):e12940
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Chiang YF, Huang KC, Chen HY, Hamdy NM, Huang TC, Chang HY, Shieh TM, Huang YJ, Hsia SM
International journal of molecular sciences 2024 Mar 31;25(7)
International journal of molecular sciences 2024 Mar 31;25(7)
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Huang QM, Long YL, Wang JN, Wu J, Tang WL, Wang XY, Zhang ZH, Zhuo YQ, Guan XH, Deng KY, Xin HB
International immunopharmacology 2024 Mar 10;129:111660
International immunopharmacology 2024 Mar 10;129:111660
Generation of homozygous and heterozygous REEP1 knockout induced pluripotent stem cell lines by CRISPR/Cas9 gene editing.
Korneck M, Leonhardt A, Schöls L, Hauser S
Stem cell research 2024 Jun;77:103378
Stem cell research 2024 Jun;77:103378
Exosomal circ50547 as a potential marker and promotor of gastric cancer progression via miR-217/HNF1B axis.
Zang X, Wang R, Wang Z, Qiu S, Zhang F, Zhou L, Shen Y, Qian H, Xu W, Jiang J
Translational oncology 2024 Jul;45:101969
Translational oncology 2024 Jul;45:101969
Induction of mesenchymal stem cell (MSC) differentiation from iPS cells using MSC medium.
Wu Y, Iwasaki K, Hashimoto Y
Dental materials journal 2024 Jan 30;43(1):20-27
Dental materials journal 2024 Jan 30;43(1):20-27
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Yuan Z, Xiong B, Liu L, Lu Y, Liu Y, Wang G, Qian Y, Diao B, Tu M
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Wang S, Huang X, Zhang G, Chen Z, Guan H, Zhou W
Cellular signalling 2024 Feb;114:110998
Cellular signalling 2024 Feb;114:110998
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression.
Zhang W, Song X, Jin Z, Zhang Y, Li S, Jin F, Zheng A
Breast cancer research : BCR 2024 Apr 9;26(1):60
Breast cancer research : BCR 2024 Apr 9;26(1):60
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
Zhou H, Chen M, Zhao C, Shao R, Xu Y, Zhao W
Cells 2024 Apr 3;13(7)
Cells 2024 Apr 3;13(7)
A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers.
Zhou DD, Zhai XT, Zhang LW, Xie ZH, Wang Y, Zhen YS, Gao RJ, Miao QF
NPJ precision oncology 2024 Apr 23;8(1):94
NPJ precision oncology 2024 Apr 23;8(1):94
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Sun Y, Chen Y, Zhao H, Wang J, Liu Y, Bai J, Hu C, Shang Z
iScience 2024 Apr 19;27(4):109340
iScience 2024 Apr 19;27(4):109340
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Cao W, Lu X, Zhong C, Wu J
Nutrition and cancer 2023;75(3):980-991
Nutrition and cancer 2023;75(3):980-991
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Zhang T, Cao W, Sun H, Yu D, Zhong C
Nutrition and cancer 2023;75(3):971-979
Nutrition and cancer 2023;75(3):971-979
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Zhu S, Yang H, Liu L, Jiang Z, Ji J, Wang X, Zhong L, Liu F, Gao X, Wang H, Zhou Y
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Li Y, Yang X, Wang F, Zhao J, Zhang C, Wu D, Yang B, Gao R, Zhao P, Zan Y, Su M, He Z, Liu Y, Wang J, Tang D
Frontiers in pharmacology 2023;14:1076815
Frontiers in pharmacology 2023;14:1076815
Selective activation of TGFβ signaling by P. gingivalis-mediated upregulation of GARP aggravates esophageal squamous cell carcinoma.
Gao S, Liu K, Jiao Y, Chen P, Gu B, Liu Y, Liang G, Shi L, Zhou F, Lamont RJ, Wang H, Qi YJ
American journal of cancer research 2023;13(5):2013-2029
American journal of cancer research 2023;13(5):2013-2029
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
Hu L, Gong P, Zhou N, Wang S, He C, Zhou Y, Li Q, Zhao X, Peng H
American journal of cancer research 2023;13(5):1766-1785
American journal of cancer research 2023;13(5):1766-1785
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
Zhou S, Huang H, Zheng Z, Zheng K, Xie L
American journal of cancer research 2023;13(12):5996-6010
American journal of cancer research 2023;13(12):5996-6010
Inhibition of Na+/H+ exchanger (NHE) 7 by 5-(N-ethyl-N-isopropyl)-Amiloride displays anti-cancer activity in non-small cell lung cancer by disrupting cancer stem cell activity and downregulating PD-L1 expression.
Wang BY, Shen HT, Lee YL, Chien PJ, Chang WW
American journal of cancer research 2023;13(10):4721-4733
American journal of cancer research 2023;13(10):4721-4733
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Kong W, Huang Y, Jiang P, Tu Y, Li N, Wang J, Zhou Q, Zheng Y, Gou S, Tian C, Yuan R
PeerJ 2023;11:e15891
PeerJ 2023;11:e15891
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
Peng Y, Sun L, Guo W, Liu Z, Wang T, Zou T, Zhou J, Yang X, Fan X
Journal of pharmacological sciences 2023 Sep;153(1):46-54
Journal of pharmacological sciences 2023 Sep;153(1):46-54
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
Liu F, Wei X, Chen Z, Chen Y, Hu P, Jin Y
Journal of cancer research and clinical oncology 2023 Sep;149(12):10737-10752
Journal of cancer research and clinical oncology 2023 Sep;149(12):10737-10752
A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability.
Zhang Z, Qiao Y, Sun Q, Peng L, Sun L
Cell death discovery 2023 Sep 23;9(1):350
Cell death discovery 2023 Sep 23;9(1):350
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Lin X, Liu YH, Zhang HQ, Wu LW, Li Q, Deng J, Zhang Q, Yang Y, Zhang C, Li YL, Hu J
Cancer cell international 2023 Sep 23;23(1):208
Cancer cell international 2023 Sep 23;23(1):208
Wnt10a downregulation contributes to MEHP-induced disruption of self-renewal and differentiation balance and proliferation inhibition in GC-1 cells: Insights from multiple transcriptomic profiling.
Hong Y, Zhou X, Li Q, Chen J, Wei Y, Wang S, Zheng X, Zhao J, Yu C, Pei J, Zhang J, Long C, Shen L, Wu S, Wei G
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:122091
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:122091
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Gong T, Wu D, Pan H, Sun Z, Yao X, Wang D, Huang Y, Li X, Guo Y, Lu Y
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study.
Guo R, Gu T, Xiao Y, Xiao T, Liu Q, Li Z, Yu J
International endodontic journal 2023 Oct;56(10):1284-1300
International endodontic journal 2023 Oct;56(10):1284-1300
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway.
Hao J, Song Z, Su J, Li L, Zou L, Zou K
Cellular signalling 2023 Oct;110:110806
Cellular signalling 2023 Oct;110:110806
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
Ikeda-Motonakano R, Hirabayashi-Nishimuta F, Yada N, Yamasaki R, Nagai-Yoshioka Y, Usui M, Nakazawa K, Yoshiga D, Yoshioka I, Ariyoshi W
Cancers 2023 Oct 26;15(21)
Cancers 2023 Oct 26;15(21)
The neonatal southern white rhinoceros ovary contains oogonia in germ cell nests.
Appeltant R, Hermes R, Holtze S, Modina SC, Galli C, Bjarkadottir BD, Adeniran BV, Wei X, Swegen A, Hildebrandt TB, Williams SA
Communications biology 2023 Oct 17;6(1):1049
Communications biology 2023 Oct 17;6(1):1049
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Ge M, Zhu J, Yi K, Chen Y, Cao W, Wang M, Xie C, Li X, Geng S, Wu J, Zhong C, Cao H, Jiang Z, Han H
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Bu J, Zhang Y, Wu S, Li H, Sun L, Liu Y, Zhu X, Qiao X, Ma Q, Liu C, Niu N, Xue J, Chen G, Yang Y, Liu C
Nature communications 2023 May 5;14(1):2602
Nature communications 2023 May 5;14(1):2602
Generation of a human embryonic stem cell line (SKLRMe004-A) carrying NKX2.5-EGFP and TBX5-Tdtomato dual fluorescent reporters.
He Z, Sun H, Yu T, Yang Y, Zhang X, Yang Y
Stem cell research 2023 Mar;67:103015
Stem cell research 2023 Mar;67:103015
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.
Sun C, Zhang K, Ni C, Wan J, Duan X, Lou X, Yao X, Li X, Wang M, Gu Z, Yang P, Li Z, Qin Z
Oncogenesis 2023 Mar 29;12(1):18
Oncogenesis 2023 Mar 29;12(1):18
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Cao WS, Zhao MJ, Chen Y, Zhu JY, Xie CF, Li XT, Geng SS, Zhong CY, Fu JY, Wu JS
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Generation of a heterozygous and a homozygous CSF1R knockout line from iPSC using CRISPR/Cas9.
Schmitz AS, Korneck M, Raju J, Lamsfus-Calle A, Daniel-Moreno A, Antony JS, Mezger M, Schöls L, Hauser S, Hayer SN
Stem cell research 2023 Jun;69:103066
Stem cell research 2023 Jun;69:103066
Human amniotic mesenchymal stem cell-conditioned medium inhibited LPS-induced cell injury and inflammation by modulating CD14/TLR4-mediated signaling pathway in monocytes.
Li M, Li T, Jin J, Xie C, Zhu J
Molecular immunology 2023 Jun;158:10-21
Molecular immunology 2023 Jun;158:10-21
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2.
Cai M, Xu S, Jin Y, Yu J, Dai S, Shi XJ, Guo R
Cell death discovery 2023 Jun 8;9(1):179
Cell death discovery 2023 Jun 8;9(1):179
SLC1A5 regulates cell proliferation and self-renewal through β-catenin pathway mediated by redox signaling in arsenic-treated uroepithelial cells.
Li S, Pei L, Zhou Q, Fu Z, Zhang L, Liu P, Yan N, Xi S
Ecotoxicology and environmental safety 2023 Jun 30;262:115204
Ecotoxicology and environmental safety 2023 Jun 30;262:115204
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Zheng JY, Zhu T, Zhuo W, Mao XY, Yin JY, Li X, He YJ, Zhang W, Liu C, Liu ZQ
Biochemical pharmacology 2023 Jul;213:115616
Biochemical pharmacology 2023 Jul;213:115616
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
Chen J, Wu Z, Deng W, Tang M, Wu L, Lin N, Chen L, Fu Y, Zhao M, Chen C, Li W
Journal of translational medicine 2023 Jul 8;21(1):453
Journal of translational medicine 2023 Jul 8;21(1):453
Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway.
Zhou F, Sun J, Ye L, Jiang T, Li W, Su C, Ren S, Wu F, Zhou C, Gao G
Experimental hematology & oncology 2023 Jul 19;12(1):61
Experimental hematology & oncology 2023 Jul 19;12(1):61
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Liu S, Wu J, Lu X, Guo C, Zheng Q, Wang Y, Hu Q, Bian S, Luo L, Cheng Q, Liu Z, Dai W
Experimental cell research 2023 Jul 1;428(1):113613
Experimental cell research 2023 Jul 1;428(1):113613
Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes.
Li H, Gu J, Sun X, Zuo Q, Li B, Gu X
Stem cell reviews and reports 2023 Jan;19(1):213-229
Stem cell reviews and reports 2023 Jan;19(1):213-229
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
Chiang YF, Huang KC, Chen HY, Huang TC, Ali M, Chang HY, Shieh TM, Shih YH, Wang KL, Huang YJ, Chung CP, Hsia SM
Biomedicines 2023 Jan 20;11(2)
Biomedicines 2023 Jan 20;11(2)
Isolation of female germline stem cells from neonatal piglet ovarian tissue and differentiation into oocyte-like cells.
Wang C, Sun Q, Li S, Liu G, Ren J, Li Y, Ding X, Zhu J, Dai Y
Theriogenology 2023 Feb;197:186-197
Theriogenology 2023 Feb;197:186-197
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
Zhu W, Ye B, Yang S, Li Y
Journal of molecular histology 2023 Dec;54(6):703-714
Journal of molecular histology 2023 Dec;54(6):703-714
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
Huang J, Sun X, Diao G, Li R, Guo J, Han J
Environmental toxicology 2023 Aug;38(8):1824-1834
Environmental toxicology 2023 Aug;38(8):1824-1834
CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway.
Wang C, Cao F, Cao J, Jiao Z, You Y, Xiong Y, Zhao W, Wang X
Journal of translational medicine 2023 Aug 12;21(1):539
Journal of translational medicine 2023 Aug 12;21(1):539
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling.
Liu H, Yan R, Xiao Z, Huang X, Yao J, Liu J, An G, Ge Y
Breast cancer research : BCR 2023 Apr 17;25(1):43
Breast cancer research : BCR 2023 Apr 17;25(1):43
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Lin Z, Lv Z, Liu X, Huang K
Journal of translational medicine 2023 Apr 10;21(1):249
Journal of translational medicine 2023 Apr 10;21(1):249
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
Hepatitis B Virus Pregenomic RNA Reflecting Viral Replication in Distal Non-tumor Tissues as a Determinant of the Stemness and Recurrence of Hepatocellular Carcinoma.
Xiao Y, Cao J, Zhang Z, Zeng C, Ou G, Shi J, Liu Z, Li Y, Deng J, Xu Y, Zhang W, Li J, Li T, Zhuang H, Lu S, Xiang K
Frontiers in microbiology 2022;13:830741
Frontiers in microbiology 2022;13:830741
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
Hu D, Zhang B, Suo Y, Li Z, Wan Z, Zhao W, Chen L, Yin Z, Ning H, Ge Y, Li W
Frontiers in pharmacology 2022;13:779664
Frontiers in pharmacology 2022;13:779664
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Xie W, Yu J, Yin Y, Zhang X, Zheng X, Wang X
Frontiers in oncology 2022;12:876257
Frontiers in oncology 2022;12:876257
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H
Environmental toxicology 2022 Sep;37(9):2133-2142
Environmental toxicology 2022 Sep;37(9):2133-2142
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Chen Y, Wang MH, Wu JY, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Li YD, Han HY, Zhong CY
The Journal of nutritional biochemistry 2022 Sep;107:109067
The Journal of nutritional biochemistry 2022 Sep;107:109067
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
Wang C, Gao Y, Liang W, Lu Y, Zhang K, Wu D, Zhuang Z, Li K, Qiao Z, Xi H, Chen L
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Yang J, Miao RR, Li YN, Pan T, Wu SH, Qu XJ, Cui SX
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Chen Y, Tang L, Ye X, Chen Y, Shan E, Han H, Zhong C
Food & function 2022 Nov 28;13(23):12363-12370
Food & function 2022 Nov 28;13(23):12363-12370
Cancer-associated fibroblasts promote the stemness and progression of renal cell carcinoma via exosomal miR-181d-5p.
Ding M, Zhao X, Chen X, Diao W, Kan Y, Cao W, Chen W, Jiang B, Qin H, Gao J, Zhuang J, Zhang Q, Guo H
Cell death discovery 2022 Nov 1;8(1):439
Cell death discovery 2022 Nov 1;8(1):439
Zuogui pills maintain the stemness of oogonial stem cells and alleviate cyclophosphamide-induced ovarian aging through Notch signaling pathway.
Zeng L, Ye J, Zhang Z, Liang Y, Li J, Zeng L, Cao L, Zhu L, Luo S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153975
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153975
Bisphenol A induces apoptosis in response to DNA damage through c-Abl/YAP(Y357)/ p73 pathway in P19 embryonal carcinoma stem cells.
Ren F, Ning H, Ge Y, Yin Z, Chen L, Hu D, Shen S, Wang X, Wang S, Li R, He J
Toxicology 2022 Mar 30;470:153138
Toxicology 2022 Mar 30;470:153138
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Jia Z, Wang K, Duan Y, Hu K, Zhang Y, Wang M, Xiao K, Liu S, Pan Z, Ding X
Cell death discovery 2022 Mar 18;8(1):122
Cell death discovery 2022 Mar 18;8(1):122
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Huang P, Zhou Y, Li XH, Zhang YN, Cheng HP, Fu JF, Liu W, Yue S, Luo ZQ
Annals of translational medicine 2022 Jun;10(11):642
Annals of translational medicine 2022 Jun;10(11):642
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
Xu X, Wang H, Li X, Duan X, Wang Y
Aging 2022 Jun 9;14(11):4858-4873
Aging 2022 Jun 9;14(11):4858-4873
Addressing Doxorubicin Resistance in Bone Sarcomas Using Novel Drug-Resistant Models.
Gallego B, Murillo D, Rey V, Huergo C, Estupiñán Ó, Rodríguez A, Tornín J, Rodríguez R
International journal of molecular sciences 2022 Jun 8;23(12)
International journal of molecular sciences 2022 Jun 8;23(12)
Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation.
Li X, Yang S, Yuan G, Jing D, Qin L, Zhao H, Yang S
Bone research 2022 Jun 23;10(1):46
Bone research 2022 Jun 23;10(1):46
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Generation of a human extended pluripotent stem cell line (SKLRMe002-A) carrying a doxycycline-inducible Cas9 expression cassette.
He Z, Feng K, Sun H, Yu T, Zhu D, Yang Y
Stem cell research 2022 Jul;62:102816
Stem cell research 2022 Jul;62:102816
Generation of an induced pluripotent stem cell line from a patient with Angelman syndrome carrying UBE3A mutation.
Li S, Zhu Q, Cai Y, Yang Q
Stem cell research 2022 Jul;62:102791
Stem cell research 2022 Jul;62:102791
Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession.
Liu YR, Song DD, Liang DM, Li YJ, Yan YF, Sun HF, Zhang ML, Hu JX, Zhao YL, Liang Y, Li YM, Yang Z, Wang RR, Zheng HF, Wang P, Xie SY
Cell death discovery 2022 Jul 5;8(1):306
Cell death discovery 2022 Jul 5;8(1):306
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Chen Q, Yang SB, Zhang YW, Han SY, Jia L, Li B, Zhang Y, Zuo S
World journal of stem cells 2022 Jul 26;14(7):539-555
World journal of stem cells 2022 Jul 26;14(7):539-555
Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus.
Yu M, Liu Y, Han Z, Du W, Chen B, Zhang L, Xue H, Zhang Z, Guo Z
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):917-930
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):917-930
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Chen Y, Zhao H, Liang W, Jiang E, Zhou X, Shao Z, Liu K, Shang Z
Oncogene 2022 Jan;41(5):634-646
Oncogene 2022 Jan;41(5):634-646
Disturbance in transcriptomic profile, proliferation and multipotency in human mesenchymal stem cells caused by hexafluoropropylene oxides.
Pan Y, Qin H, Zheng L, Guo Y, Liu W
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118483
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118483
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
Xu Y, Tang Z, Dai H, Hou J, Li F, Tang Z, Zhang D
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis.
Sasabe E, Tomomura A, Liu H, Sento S, Kitamura N, Yamamoto T
Cancer science 2022 Feb;113(2):609-621
Cancer science 2022 Feb;113(2):609-621
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Wei J, Zheng X, Li W, Li X, Fu Z
Cancer cell international 2022 Feb 11;22(1):75
Cancer cell international 2022 Feb 11;22(1):75
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Jiang J, Cheng Y, Dai S, Zou B, Guo X
Environmental toxicology 2022 Aug;37(8):1944-1956
Environmental toxicology 2022 Aug;37(8):1944-1956
Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop.
Shen Y, Zhu Q, Xiao M, Yin L, Feng W, Feng J, He J, Li P, Chen X, Ding W, Zhong J, Zeng Z, Xie Z, Liu J, Zu X
Cell death & disease 2022 Aug 30;13(8):749
Cell death & disease 2022 Aug 30;13(8):749
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
Yan W, Hao F, Zhe X, Wang Y, Liu D
BMC veterinary research 2022 Aug 15;18(1):313
BMC veterinary research 2022 Aug 15;18(1):313
Generation of two SPAST knockout human induced pluripotent stem cell lines to create a model for Hereditary Spastic Paraplegia type 4.
Korneck M, Wiora L, Schöls L, Hauser S
Stem cell research 2022 Apr;60:102741
Stem cell research 2022 Apr;60:102741
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
Zhang Y, Lin W, Jiang W, Wang Z
Bioengineered 2022 Apr;13(4):9959-9972
Bioengineered 2022 Apr;13(4):9959-9972
Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma.
Wang X, Li R, Wu L, Chen Y, Liu S, Zhao H, Wang Y, Wang L, Shao Z
Cell & bioscience 2022 Apr 27;12(1):49
Cell & bioscience 2022 Apr 27;12(1):49
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling.
Peng Z, Liu L, Zhang W, Wei X
Stem cells international 2021;2021:8898506
Stem cells international 2021;2021:8898506
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Gao W, Wen H, Liang L, Dong X, Du R, Zhou W, Zhang X, Zhang C, Xiang R, Li N
Theranostics 2021;11(6):2564-2580
Theranostics 2021;11(6):2564-2580
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, Jiang M, Lin W, Zhang Y, Lin W, Zhou R, Zhao L
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
Li C, Cheng D, Xu P, Nie H, Zhang T, Pang X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
An iPS cell line SDUBMSi0011-A from a multiple epiphyseal dysplasia patient carrying c. 1076T > G mutation in the SMOC2 gene.
Long F, Liu X, Liu Y, Liu Q, Sun W
Stem cell research 2021 May;53:102353
Stem cell research 2021 May;53:102353
Generation of two induced pluripotent stem cell lines from patients with X-linked Alport syndrome.
Ma Y, Wang Z, Gao M, Liu X, Sun W, Gong Y, Sun G, Liu G
Stem cell research 2021 May;53:102343
Stem cell research 2021 May;53:102343
Generation of an induced pluripotent stem cell line SDUBMSi005-A from a patient with double primary gastric and colon carcinoma.
Li Y, Liu X, Chen D, Liu Y, Ma Y, Liu Q, Sun W, Li J
Stem cell research 2021 May;53:102253
Stem cell research 2021 May;53:102253
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849
Environmental toxicology 2021 May;36(5):840-849
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Gu X, Li X, Jin Y, Zhang Z, Li M, Liu D, Wei F
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126
Cell death discovery 2021 May 29;7(1):126
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Ren S, Xiong H, Chen J, Yang X, Liu Y, Guo J, Jiang T, Xu Z, Yuan M, Liu Y, Zhou N, Chen H, Li W, Machens HG, Chen Z
Stem cell research & therapy 2021 May 29;12(1):313
Stem cell research & therapy 2021 May 29;12(1):313
Establishment of patient-specific induced pluripotent stem cell line SDUBMSi009-A from a patient with X-linked Lowe syndrome.
Liu X, Liu Y, Ma Y, Gong Y, Liu Q, Sun W, Guo H
Stem cell research 2021 Mar;51:102171
Stem cell research 2021 Mar;51:102171
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
Geng H, Guo W, Feng L, Xie D, Bi L, Wang Y, Zhang T, Liang Z, Yu D
The Journal of international medical research 2021 Mar;49(3):300060521992900
The Journal of international medical research 2021 Mar;49(3):300060521992900
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
Graphene Quantum Dots Disrupt Embryonic Stem Cell Differentiation by Interfering with the Methylation Level of Sox2.
Ku T, Hao F, Yang X, Rao Z, Liu QS, Sang N, Faiola F, Zhou Q, Jiang G
Environmental science & technology 2021 Mar 2;55(5):3144-3155
Environmental science & technology 2021 Mar 2;55(5):3144-3155
p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response.
Li C, Huang Y, Fan Q, Quan H, Dong Y, Nie M, Wang J, Xie F, Ji J, Zhou L, Zheng Z, Wang L
Cell death & disease 2021 Mar 17;12(4):286
Cell death & disease 2021 Mar 17;12(4):286
EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis.
Wang K, Wang Y, Wang Y, Liu S, Wang C, Zhang S, Zhang T, Yang X
Stem cell research & therapy 2021 Mar 16;12(1):186
Stem cell research & therapy 2021 Mar 16;12(1):186
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Xu H, Liu T, Li W, Yao Q
Environmental toxicology 2021 Jun;36(6):1090-1098
Environmental toxicology 2021 Jun;36(6):1090-1098
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
Effects of shikonin on the development of ovarian follicles and female germline stem cells.
Ma SX, Tang LB, Chen ZH, Wei ML, Tang ZJ, Zheng YH, Zong G, Li J
The Journal of international medical research 2021 Jul;49(7):3000605211029461
The Journal of international medical research 2021 Jul;49(7):3000605211029461
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy.
Ordureau A, Kraus F, Zhang J, An H, Park S, Ahfeldt T, Paulo JA, Harper JW
Molecular cell 2021 Dec 16;81(24):5082-5098.e11
Molecular cell 2021 Dec 16;81(24):5082-5098.e11
Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells.
Qiu W, Guo X, Li B, Wang J, Qi Y, Chen Z, Zhao R, Deng L, Qian M, Wang S, Zhang Z, Guo Q, Zhang S, Pan Z, Zhao S, Xue H, Li G
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Dec 1;29(12):3449-3464
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Dec 1;29(12):3449-3464
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
Wang K, Chen X, Zuyi W, Chen L, Fu W
Environmental toxicology 2021 Aug;36(8):1654-1663
Environmental toxicology 2021 Aug;36(8):1654-1663
Generation and characterization of an integration-free iPSC line SDUBMSi006-A from a patient with Alport syndrome caused by COL4A3 gene mutations.
Ma Y, Wang Z, Liu X, Sun W, Gong Y, Liu G, Sun G
Stem cell research 2021 Apr;52:102237
Stem cell research 2021 Apr;52:102237
Comparative Transcriptional Profiling of Motor Neuron Disorder-Associated Genes in Various Human Cell Culture Models.
Hauser S, Schuster S, Heuten E, Höflinger P, Admard J, Schelling Y, Velic A, Macek B, Ossowski S, Schöls L
Frontiers in cell and developmental biology 2020;8:544043
Frontiers in cell and developmental biology 2020;8:544043
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
CCL21/CCR7 interaction promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3 signaling pathway.
Chen Y, Shao Z, Jiang E, Zhou X, Wang L, Wang H, Luo X, Chen Q, Liu K, Shang Z
Journal of cellular physiology 2020 Sep;235(9):5995-6009
Journal of cellular physiology 2020 Sep;235(9):5995-6009
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Shao L, Zhang X, Yao Q
FEBS open bio 2020 Sep;10(9):1810-1820
FEBS open bio 2020 Sep;10(9):1810-1820
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
Fu XP, Xu L, Fu BB, Wei KN, Liu Y, Liao BQ, He SW, Wang YL, Chen MH, Lin YH, Li FP, Hong ZW, Huang XH, Xu CL, Wang HL
Biology of reproduction 2020 Oct 29;103(5):1085-1098
Biology of reproduction 2020 Oct 29;103(5):1085-1098
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Chen Y, Wang MH, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Han HY, Zhong CY
Oncogenesis 2020 Oct 10;9(10):89
Oncogenesis 2020 Oct 10;9(10):89
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Zhang T, Sun H, Liu R, Cao W, Zhang T, Li E, Sun X, Wu W, Yu D, Zhong C
Environmental toxicology 2020 Nov;35(11):1274-1283
Environmental toxicology 2020 Nov;35(11):1274-1283
Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.
Chen F, Zhu L, Hu J, Jiang S, Liu H, Zheng J, Wang J, Wang F, Li Z
Oncology letters 2020 Nov;20(5):171
Oncology letters 2020 Nov;20(5):171
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Lv Y, Wang X, Li X, Xu G, Bai Y, Wu J, Piao Y, Shi Y, Xiang R, Wang L
PLoS biology 2020 Nov;18(11):e3000872
PLoS biology 2020 Nov;18(11):e3000872
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
A Combined Systemic Strategy for Overcoming Cisplatin Resistance in Head and Neck Cancer: From Target Identification to Drug Discovery.
Chen YJ, You GR, Lai MY, Lu LS, Chen CY, Ting LL, Lee HL, Kanno Y, Chiou JF, Cheng AJ
Cancers 2020 Nov 23;12(11)
Cancers 2020 Nov 23;12(11)
Generation of a human induced pluripotent stem cell line (SDUBMSi001-A) from a hereditary spastic paraplegia patient carrying kif1a c.773C>T missense mutation.
Xiaojing W, Yanyan M, Ruonan D, Xiaolin L, Haiyan Z, Jian M, Yi L, Wenjie S, Qiji L
Stem cell research 2020 Mar;43:101727
Stem cell research 2020 Mar;43:101727
Generation of patient-specific pluripotent induced stem cell line SDUBMSI002-A from a patient with X-linked mental retardation syndrome.
Liu X, Yang X, Li Y, Wang X, Ma J, Jiang W, Liu Y, Sun W, Gong Y
Stem cell research 2020 Mar;43:101724
Stem cell research 2020 Mar;43:101724
miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8.
Zhang J, Wang C, Yan S, Yang Y, Zhang X, Guo W
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):259-267
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):259-267
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Guo Y, Yuan X, Li K, Dai M, Zhang L, Wu Y, Sun C, Chen Y, Cheng G, Liu C, Strååt K, Kong F, Zhao S, Bjorkhölm M, Xu D
Cell death and differentiation 2020 Jun;27(6):1862-1877
Cell death and differentiation 2020 Jun;27(6):1862-1877
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Chen M, Ye A, Wei J, Wang R, Poon K
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Generation of the CRISPR/Cas9-mediated KIF1C knock-out human iPSC line HIHRSi003-A-1.
Nagel M, Müßig S, Höflinger P, Schöls L, Hauser S, Schüle R
Stem cell research 2020 Dec;49:102059
Stem cell research 2020 Dec;49:102059
MicroRNA‑487b‑3p inhibits osteosarcoma chemoresistance and metastasis by targeting ALDH1A3.
Cheng M, Duan PG, Gao ZZ, Dai M
Oncology reports 2020 Dec;44(6):2691-2700
Oncology reports 2020 Dec;44(6):2691-2700
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Deng K, Liu L, Tan X, Zhang Z, Li J, Ou Y, Wang X, Yang S, Xiang R, Sun P
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Pouraghaei S, Moztarzadeh F, Chen C, Ansari S, Moshaverinia A
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Limbal niche cells can reduce the angiogenic potential of cultivated oral mucosal epithelial cells.
Duan CY, Xie HT, Zhao XY, Xu WH, Zhang MC
Cellular & molecular biology letters 2019;24:3
Cellular & molecular biology letters 2019;24:3
Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities.
Guo Y, Wang P, Ma JH, Cui Z, Yu Q, Liu S, Xue Y, Zhu D, Cao J, Li Z, Tang S, Chen J
Frontiers in cellular neuroscience 2019;13:361
Frontiers in cellular neuroscience 2019;13:361
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Napabucasin Attenuates Resistance of Breast Cancer Cells to Tamoxifen by Reducing Stem Cell-Like Properties.
Liu X, Huang J, Xie Y, Zhou Y, Wang R, Lou J
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 24;25:8905-8912
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 24;25:8905-8912
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Liu YQ, Wang SK, Xu QQ, Yuan HQ, Guo YX, Wang Q, Kong F, Lin ZM, Sun DQ, Wang RM, Lou HX
Acta pharmacologica Sinica 2019 May;40(5):689-698
Acta pharmacologica Sinica 2019 May;40(5):689-698
PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma.
Cao Y, Liu H, Xia SL, Zhang X, Bai H, Yang Q, Li J, Gao L, Jin F, Wei MJ, Lu SL, Xiao J
Oncology reports 2019 Mar;41(3):1827-1836
Oncology reports 2019 Mar;41(3):1827-1836
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation.
Liu X, Fu Y, Huang J, Wu M, Zhang Z, Xu R, Zhang P, Zhao S, Liu L, Jiang H
Journal of experimental & clinical cancer research : CR 2019 Jul 17;38(1):315
Journal of experimental & clinical cancer research : CR 2019 Jul 17;38(1):315
In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.
Zhang HB, Chen FZ, He SH, Liang YB, Wang ZQ, Wang L, Chen ZR, Ding W, Zhao SC, Wei AY
Stem cell research & therapy 2019 Jul 16;10(1):208
Stem cell research & therapy 2019 Jul 16;10(1):208
Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus.
Schuster S, Saravanakumar S, Schöls L, Hauser S
Stem cell research 2019 Jan;34:101378
Stem cell research 2019 Jan;34:101378
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, Deng X, Zhang Z, Shao Z
Cancer medicine 2019 Dec;8(17):7345-7358
Cancer medicine 2019 Dec;8(17):7345-7358
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Ai L, Mu S, Sun C, Fan F, Yan H, Qin Y, Cui G, Wang Y, Guo T, Mei H, Wang H, Hu Y
Molecular cancer 2019 Apr 13;18(1):88
Molecular cancer 2019 Apr 13;18(1):88
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y
Theranostics 2018;8(14):3932-3948
Theranostics 2018;8(14):3932-3948
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Peng X, Kang Q, Wan R, Wang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells.
Xu R, Zhu X, Chen F, Huang C, Ai K, Wu H, Zhang L, Zhao X
Cancer cell international 2018;18:41
Cancer cell international 2018;18:41
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
Ye J, Liu S, Shang Y, Chen H, Wang R
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation.
Xiao G, Li Y, Wang M, Li X, Qin S, Sun X, Liang R, Zhang B, Du N, Xu C, Ren H, Liu D
Cell proliferation 2018 Oct;51(5):e12473
Cell proliferation 2018 Oct;51(5):e12473
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, Mao J, Lu Y, Yang J, Yu X, Zhang Q, Zhang J, Song B, Li M, Li L
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness.
Li C, Fan Q, Quan H, Nie M, Luo Y, Wang L
Experimental cell research 2018 Jun 15;367(2):170-185
Experimental cell research 2018 Jun 15;367(2):170-185
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Wang W, Chen D, Zhu K
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Integration-free reprogramming of human umbilical arterial endothelial cells into induced pluripotent stem cells IHSTMi001-A.
Li H, Pei H, Nie J, Qu M, Fan Z, Jia Y, He L, Nan X, Yue W, Pei X
Stem cell research 2018 Aug;31:231-234
Stem cell research 2018 Aug;31:231-234
Disulfiram/copper targets stem cell-like ALDH(+) population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
Jin N, Zhu X, Cheng F, Zhang L
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Bufalin Inhibits Cellular Proliferation and Cancer Stem Cell-Like Phenotypes via Upregulation of MiR-203 in Glioma.
Liu T, Wu C, Weng G, Zhao Z, He X, Fu C, Sui Z, Huang SX
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):671-681
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):671-681
NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes.
Wu X, Yang B, Hu Y, Sun R, Wang H, Fu J, Hou Y, Pi J, Xu Y
Oxidative medicine and cellular longevity 2017;2017:7417694
Oxidative medicine and cellular longevity 2017;2017:7417694
Soluble expression of recomb inant cMyc, Klf4, Oct4, and Sox2 proteins in bacteria and transduction into living cells.
Liu GD, Zhou SF, Ding XC, Fang CL, Mi SY, Gao XC, Han Q
International journal of ophthalmology 2017;10(4):560-566
International journal of ophthalmology 2017;10(4):560-566
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Sun J, Xu K, Qiu Y, Gao H, Xu J, Tang Q, Yin P
Oncology reports 2017 Sep;38(3):1420-1430
Oncology reports 2017 Sep;38(3):1420-1430
Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice.
Liu J, Shang D, Xiao Y, Zhong P, Cheng H, Zhou R
The Journal of biological chemistry 2017 Sep 29;292(39):16003-16013
The Journal of biological chemistry 2017 Sep 29;292(39):16003-16013
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Zhang L, Yan Y, Jiang Y, Qian J, Jiang L, Hu G, Lu Y, Luo C
Oncology letters 2017 Oct;14(4):4263-4269
Oncology letters 2017 Oct;14(4):4263-4269
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
Yu X, Zhang F, Mao J, Lu Y, Li J, Ma W, Fan S, Zhang C, Li Q, Wang B, Song B, Li L
Oncotarget 2017 Nov 17;8(58):98798-98811
Oncotarget 2017 Nov 17;8(58):98798-98811
Silencing of Btbd7 Inhibited Epithelial-Mesenchymal Transition and Chemoresistance in CD133(+) Lung Carcinoma A549 Cells.
Fang LZ, Zhang JQ, Liu L, Fu WP, Shu JK, Feng JG, Liang X
Oncology research 2017 May 24;25(5):819-829
Oncology research 2017 May 24;25(5):819-829
Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma.
Xiao W, Gao Z, Duan Y, Yuan W, Ke Y
Journal of experimental & clinical cancer research : CR 2017 Mar 9;36(1):41
Journal of experimental & clinical cancer research : CR 2017 Mar 9;36(1):41
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Wu Y, Li O, He C, Li Y, Li M, Liu XL, Wang Y, He Y
Molecular medicine reports 2017 Jun;15(6):3690-3698
Molecular medicine reports 2017 Jun;15(6):3690-3698
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Gao Y, Zhang Z, Li K, Gong L, Yang Q, Huang X, Hong C, Ding M, Yang H
Cell death & disease 2017 Jul 13;8(7):e2924
Cell death & disease 2017 Jul 13;8(7):e2924
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells.
Hsieh CH, Hsiung SC, Yeh CT, Yen CF, Chou YW, Lei WY, Pang ST, Chuang CK, Liao SK
Oncotarget 2017 Feb 28;8(9):15593-15609
Oncotarget 2017 Feb 28;8(9):15593-15609
Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3β-involved Wnt/β-catenin pathway.
Chen S, Sun YY, Zhang ZX, Li YH, Xu ZM, Fu WN
Oncotarget 2017 Feb 28;8(9):14708-14718
Oncotarget 2017 Feb 28;8(9):14708-14718
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
NANOG overexpression and its correlation with stem cell and differentiation markers in meningiomas of different WHO grades.
Freitag D, McLean AL, Simon M, Koch A, Grube S, Walter J, Kalff R, Ewald C
Molecular carcinogenesis 2017 Aug;56(8):1953-1964
Molecular carcinogenesis 2017 Aug;56(8):1953-1964
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas.
Gao Z, Cai L, Lu J, Wang C, Li Q, Chen J, Song X, Chen X, Zhang L, Zheng W, Su Z
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 15;23:1827-1833
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 15;23:1827-1833
Enhanced tenogenic differentiation and tendon-like tissue formation by CHIP overexpression in tendon-derived stem cells.
Han W, Chen L, Liu J, Guo A
Acta biochimica et biophysica Sinica 2017 Apr 1;49(4):311-317
Acta biochimica et biophysica Sinica 2017 Apr 1;49(4):311-317
CD44+ cancer cell-induced metastasis: A feasible neck metastasis model.
Wu TF, Chen L, Bu LL, Gao J, Zhang WF, Jia J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Apr 1;101:243-250
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Apr 1;101:243-250
miR-612 suppresses stem cell-like property of hepatocellular carcinoma cells by modulating Sp1/Nanog signaling.
Liu Y, Liu DL, Dong LL, Wen D, Shi DM, Zhou J, Fan J, Wu WZ
Cell death & disease 2016 Sep 29;7(9):e2377
Cell death & disease 2016 Sep 29;7(9):e2377
A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.
Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K
Stem cell reports 2016 May 10;6(5):704-716
Stem cell reports 2016 May 10;6(5):704-716
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Wang B, Sun J, Shi J, Guo Q, Tong X, Zhang J, Hu N, Hu Y
Journal of biomolecular screening 2016 Jul;21(6):634-42
Journal of biomolecular screening 2016 Jul;21(6):634-42
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
Wu Y, Shu J, He C, Li M, Wang Y, Ou W, He Y
Theriogenology 2016 Jan 15;85(2):302-14
Theriogenology 2016 Jan 15;85(2):302-14
Specific detection of OCT4 isoforms in inflammatory bowel disease.
Maragkoudaki M, Vaiopoulou A, Theodoropoulos GE, Legaki E, Sechi LA, Karamanolis G, Zografos G, Gazouli M
Gut pathogens 2015;7:25
Gut pathogens 2015;7:25
The Expression of Markers Related to Ovarian Germline Stem Cells in the Mouse Ovarian Surface Epithelium and the Correlation with Notch Signaling Pathway.
Pan Z, Sun M, Li J, Zhou F, Liang X, Huang J, Zheng T, Zheng L, Zheng Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(6):2311-22
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(6):2311-22
Hyperglycemic Stress Impairs the Stemness Capacity of Kidney Stem Cells in Rats.
Yang G, Jia Y, Li C, Cheng Q, Yue W, Pei X
PloS one 2015;10(10):e0139607
PloS one 2015;10(10):e0139607
Silencing JARID1B suppresses oncogenicity, stemness and increases radiation sensitivity in human oral carcinoma.
Lin CS, Lin YC, Adebayo BO, Wu A, Chen JH, Peng YJ, Cheng MF, Lee WH, Hsiao M, Chao TY, Yeh CT
Cancer letters 2015 Nov 1;368(1):36-45
Cancer letters 2015 Nov 1;368(1):36-45
Vacuolar ATPase in phagosome-lysosome fusion.
Kissing S, Hermsen C, Repnik U, Nesset CK, von Bargen K, Griffiths G, Ichihara A, Lee BS, Schwake M, De Brabander J, Haas A, Saftig P
The Journal of biological chemistry 2015 May 29;290(22):14166-80
The Journal of biological chemistry 2015 May 29;290(22):14166-80
Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells.
Umazume T, Thomas WM, Campbell S, Aluri H, Thotakura S, Zoukhri D, Makarenkova HP
Investigative ophthalmology & visual science 2015 Dec;56(13):8392-402
Investigative ophthalmology & visual science 2015 Dec;56(13):8392-402
Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.
Zheng Y, Zou F, Wang J, Yin G, Le V, Fei Z, Liu J
The Journal of biological chemistry 2015 Apr 3;290(14):8975-86
The Journal of biological chemistry 2015 Apr 3;290(14):8975-86
MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1.
Lin Y, Liu AY, Fan C, Zheng H, Li Y, Zhang C, Wu S, Yu D, Huang Z, Liu F, Luo Q, Yang CJ, Ouyang G
Scientific reports 2015 Apr 28;5:9995
Scientific reports 2015 Apr 28;5:9995
Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition.
Ma SR, Wang WM, Huang CF, Zhang WF, Sun ZJ
Oncotarget 2015 Apr 20;6(11):8807-21
Oncotarget 2015 Apr 20;6(11):8807-21
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
Tao H, Li H, Su Y, Feng D, Wang X, Zhang C, Ma H, Hu Q
Molecular and cellular biochemistry 2014 Sep;394(1-2):23-30
Molecular and cellular biochemistry 2014 Sep;394(1-2):23-30
Hepatitis B virus X protein upregulates Lin28A/Lin28B through Sp-1/c-Myc to enhance the proliferation of hepatoma cells.
You X, Liu F, Zhang T, Lv N, Liu Q, Shan C, Du Y, Kong G, Wang T, Ye L, Zhang X
Oncogene 2014 Jan 23;33(4):449-60
Oncogene 2014 Jan 23;33(4):449-60
Correlation of ALDH1, CD44, OCT4 and SOX2 in tongue squamous cell carcinoma and their association with disease progression and prognosis.
Huang CF, Xu XR, Wu TF, Sun ZJ, Zhang WF
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Aug;43(7):492-8
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Aug;43(7):492-8
Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer.
Kong D, Su G, Zha L, Zhang H, Xiang J, Xu W, Tang Y, Wang Z
Medical oncology (Northwood, London, England) 2014 Aug;31(8):130
Medical oncology (Northwood, London, England) 2014 Aug;31(8):130
Expression of Oct-4, SOX-2, and MYC in dental papilla cells and dental follicle cells during in-vivo tooth development and in-vitro co-culture.
Peng Z, Liu L, Wei X, Ling J
European journal of oral sciences 2014 Aug;122(4):251-8
European journal of oral sciences 2014 Aug;122(4):251-8
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.
Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, Volpin F, Indraccolo S, Scienza R, Basso G
Cell death & disease 2012 Oct 18;3(10):e412
Cell death & disease 2012 Oct 18;3(10):e412
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- hESC cells were subjected to SDS PAGE followed by western blot with 11263-1-AP(OCT4 antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of human embronic stem cells with 11263-1-AP at dilution of 1:50. The FITC shows staining with 11263-1-AP/FITC. The DAPI shows nuclear staining by DAPI. The MERGE is the merge of FITC and DAPI.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of human embronic stem cells with 11263-1-AP at dilution of 1:100. The PE shows staining with 11263-1-AP/PE. The DAPI shows nuclear staining by DAPI. The MERGE is the merge of PE and DAPI.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11263-1-AP(OCT4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
