POU5F1

gene product
MGC22487, OCT3, Oct4, OTF3
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
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Validated within AVI
Eligible for validation within AVI
1273 antibodies from 46 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
13 antibodies
Invitrogen Antibodies
25 antibodies
R&D Systems
14 antibodies
Novus Biologicals
125 antibodies
antibodies-online
453 antibodies
OriGene
59 antibodies
Acris Antibodies GmbH
34 antibodies
Cell Signaling Technology, Inc
11 antibodies
Abnova Corporation
17 antibodies
Boster Biological Technology
1 antibody
Biorbyt
51 antibodies
Proteintech Group
2 antibodies
NovoPro Bioscience Inc.
10 antibodies
LifeSpan BioSciences, Inc.
163 antibodies