Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx016067 - Provider product page
- Provider
- Abbexa
- Product name
- POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
- Antibody type
- Monoclonal
- Description
- This gene encodes a transcription factor containing a POU homeodomain.This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency.A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation.Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon.Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain.Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.Low levels of expression in adult tissues.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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