LPIN1

gene product
KIAA0188
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
391 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
90 antibodies
Novus Biologicals
65 antibodies
GeneTex
5 antibodies
OriGene
24 antibodies
LifeSpan BioSciences, Inc.
59 antibodies
Abnova Corporation
6 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
Invitrogen Antibodies
9 antibodies
R&D Systems
2 antibodies
Abgent
4 antibodies
Cell Signaling Technology, Inc
2 antibodies
Affinity Biosciences
3 antibodies
ProSci
3 antibodies
Biorbyt
23 antibodies
RabMAbs
2 antibodies
Aviva Systems Biology
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
MyBioSource
6 antibodies
Acris Antibodies GmbH
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
St John's Laboratory
4 antibodies
Abbiotec
2 antibodies
Creative Biolabs
16 antibodies
United States Biological
15 antibodies
Creative Diagnostics
2 antibodies
EMD Millipore
2 antibodies
Bethyl Laboratories
1 antibody
Everest Biotech
1 antibody
Sigma-Aldrich
1 antibody