Tissue expression
Cell line expression
Protein structure

HLA-B

Major histocompatibility complex, class I, B
AS 
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
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814 antibodies from 36 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
45 antibodies
Proteintech Group
1 antibody
antibodies-online
248 antibodies
Novus Biologicals
38 antibodies
Biorbyt
81 antibodies
NovoPro Bioscience Inc.
1 antibody
NSJ Bioreagents
9 antibodies
Aviva Systems Biology
6 antibodies
GeneTex
7 antibodies
OriGene
9 antibodies
St John's Laboratory
22 antibodies
Everest Biotech
2 antibodies
HUABIO Research
2 antibodies
Abnova Corporation
7 antibodies
Santa Cruz Biotechnology
1 antibody
Antibodies.com
4 antibodies
RabMAbs
4 antibodies
Affinity Biosciences
1 antibody
BioLegend
5 antibodies
Acris Antibodies GmbH
7 antibodies
Creative Biolabs
29 antibodies
Abgent
1 antibody
Miltenyi Biotec
86 antibodies
Leading Biology
18 antibodies
Abbexa
13 antibodies
MyBioSource
6 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Boster Biological Technology
1 antibody
Molecular Depot LLC
1 antibody
Creative Diagnostics
10 antibodies
International Blood Group Reference Laboratory
1 antibody
United States Biological
15 antibodies
Arigo
2 antibodies
ProSci
1 antibody