SGCZ

The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008]

Description

Sarcoglycan zeta

Tissue specificity

Group enriched (brain, ovary)

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

8 (14084845 - 15238431)

Ensembl ID

ENSG00000185053  (ver. 103.38)

Orthologs

Mouse Sgcz: ENSMUSG00000039539

UniProt

Q96LD1

neXtProt

NX_Q96LD1

Human splice variants
Mouse splice variants

Protein structure