503004

antibody from BioLegend

Targeting: LTA LT, TNFB, TNFSF1

ELISA (Data presented on provider website)

Blocking/Neutralizing (Recommended by provider)

Other assay (Recommended by provider)

Antibody Data

Product number

503004

Provider

BioLegend

Proper citation

BioLegend Cat#503004, RRID:AB_315270

Product name

LEAF™ Purified anti-human TNF-â [359-238-8]

Antibody type

Monoclonal

Antigen

E.coli expressed, recombinant human TNF-β

Description

Tumor necrosis factor-beta (TNF-β), also known as lymphotoxin-α (LT-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF-β possesses a signal peptide sequence and is a secreted protein; however, TNF-β is also present on the surface of activated T, B and LAK cells as a complex with LT-β. Bioactive TNF-β exists as a homotrimer. The 359-238-8 antibody can neutralize the bioactivity of natural or recombinant human TNF-β.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

500 µg

Concentration

1 mg/ml

Storage

The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.