Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
LTA
Lymphotoxin alphaLT, TNFB, TNFSF1
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Top validated antibodies |
|||||
| antibodies-online |  ABIN453171 |
2 references | Polyclonal |
WB
EL
IHC
FC
|
|
| LSBio | LS-B11428 |
Polyclonal |
WB
EL
IHC
|
||
| Atlas Antibodies | HPA007729 |
2 references | Polyclonal |
WB
IHC
|
|
| GeneTex | GTX50003 |
1 references | Monoclonal |
WB
EL
ICC
|
|
| Abnova Corporation | MAB8481 |
3 references | Monoclonal |
WB
ICC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider