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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 503105 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#503105, RRID:AB_315275
- Product name
- PE anti-human TNF-
- Antibody type
- Monoclonal
- Antigen
- E.coli expressed, recombinant human TNF-β
- Description
- Tumor necrosis factor-beta (TNF-β), also known as lymphotoxin-α (LT-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF-β possesses a signal peptide sequence and is a secreted protein; however, TNF-β is also present on the surface of activated T, B and LAK cells as a complex with LT-β. Bioactive TNF-β exists as a homotrimer. The 359-81-11 antibody reacts with human tumor necrosis factor-beta (TNF-β). The 359-81-11 antibody can neutralize the bioactivity of natural or recombinant TNF-β.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.2 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- PMA+ionomycin-stimulated human T cells were surface stained with CD3 PE/Cy5 and intracellular stained with 359-81-11 PE
- Conjugate
- Yellow dye
