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- References [725]
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- Product number
- 60291-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TNF Alpha antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated TNF Alpha antibody (Cat. #60291-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 7B8A11
- Vial size
- 20ul, 150ul
Submitted references α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.
Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.
Protocatechualdehyde-functionalized BMSC-derived exosomes orchestrate calcium signaling in the immunoinflammatory microenvironment to promote periodontal regeneration.
CSF1 regulates inflammation and apoptosis in intervertebral disc degeneration.
CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation.
Combined single-cell transcriptome and immune repertoire analysis reveals hepatic and renal immune injury by heat stroke.
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Procyanidin capsules attenuate PI3K/AKT-mediated mitochondrial dysfunction and accelerate skin wound healing in diabetic mice.
Shaoyao Gancao Decoction ameliorates rheumatoid arthritis via inhibition of TNF-α/NF-κB signaling pathway.
Gastrin releasing peptide receptor antagonism in the paraventricular nucleus exerts antihypertensive effects in 2K1C rats.
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury.
Low-dose urapidil mitigates renal ischemia-reperfusion injury through matrix metalloproteinase-9 inhibition and anti-inflammatory effects.
Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
Modulation of the NF-κB signaling pathway by the combined strategy of tocilizumab and dexamethasone for asthma therapy.
Poria cocos Attenuates LPS/D-Galactosamine-Induced Acute Liver Failure in Rats: An Integrative Exploratory Study Combining Network Pharmacology and In Vivo Validation.
Propyl Gallate Mitigates Gastric Injury Caused by Indomethacin in Wistar Rats.
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Ezetimibe attenuates diabetic retinopathy via NRF2-mediated suppression of inflammation and oxidative stress.
BvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB.
Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Construction of a Novel Mucin/Tannic Acid Hydrogel for Diabetic Wound Repair.
Engineered CCR2 Cell Membrane-Wrapped Cepharanthine Liposomes for Potential Targeted Attenuation of Acute Lung Injury.
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Ophiopogon japonicus-derived plant exosomes: a promising strategy for blocking the progression of diabetic vasculopathy to myocardial infarction.
Exosomes derived from bone marrow mesenchymal stem cells facilitate repair of radiation-Induced skin injury by attenuating inflammation and apoptosis.
Cigarette Smoke Extract Combined with LPS Upregulates PITPβ Expression in Chronic Pulmonary Inflammation and May Be Related to the EGFR/ERK Signaling Pathway.
Therapeutic targets established in adult ulcerative colitis exhibit correlations with disease severity and pathological relevance in pediatric pouchitis.
Mucoadhesive and corneal permeable nano eye drops for improved anti-glaucoma therapy.
7,7"-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma.
A tri-component hydrogel composed of Bletilla striata polysaccharide, carboxymethyl chitosan and cinnamaldehyde: Potent enhancement of diabetic wound healing.
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Kaempferol Mitigates Liver Injury Induced by Copper Toxicity Through the Activation of the Sirt1/Nrf2/FOXO3 Signaling Pathway.
Customized ultra-flexible and adhesive spinal cord stimulation electrode for chronic pain management.
White light-triggered cascade NO/ROS-releasing platform with synergistic antibacterial and angiogenic effects for infected wound healing.
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
Hypoxia-activated dual donors of H(2)S and NO alleviate myocardial injury in coronary heart disease via synergistic mechanisms.
Lp-PLA2-derived LysoPC drives dendritic cell immunogenic activation and Th17 inflammation in severe asthma.
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
α-hederin Targets USP5 to Inhibit Colorectal Tumorigenesis by Disrupting STAT3 Deubiquitination.
miR-200a-3p in Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuates UVB-Induced Skin Inflammatory Response and Oxidative Stress via Keap1-Nrf2 Pathway.
Temporal Effects of Disease Signature Genes and Core Mechanisms in the Hyperacute Phase of Acute Ischemic Stroke: A Bioinformatics Analysis and Experimental Validation.
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling.
Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated Pyroptosis.
Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis.
Neuroprotective potential of isofraxidin: Alleviating parkinsonian symptoms, inflammation and microglial activation.
Investigating the mechanisms of Sini San in alleviating inflammatory responses via multi-omics and the BDNF/TrkB/PI3K/AKT signaling pathway in depressive model rats.
Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice.
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway.
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.
Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice.
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Senescent Microglia Mediate Neuroinflammation-Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1.
Investigating the abnormalities and potential therapeutic targets in umbilical cord mesenchymal stem cells from preeclampsia.
Flavonoids in Rosa roxburghii Tratt Fermentation Broth Ameliorate Obesity via DNMT3a/SIRT1-Mediated Epigenetic Modulation.
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
Investigating the Mechanism of Yiqi Huoxue Jieyu Granules Against Ischemic Stroke Through Network Pharmacology, Molecular Docking and Experimental Verification.
Chronic kidney disease facilitates TNF-α + neutrophils dysfunction and progression in oral squamous cell carcinoma.
Targeting Bcl3/NF-κB p50 Pathway for Neuroinflammation Attenuation and RGCs Protection in Retinal Ischemia/Reperfusion Injury.
Single-Cell Transcriptomics of Human Pericarotid Lymph Nodes Indicating Stability of Carotid Atherosclerotic Plaques.
Diosmetin Alleviates Cerebral Ischemia/Reperfusion Injury by Modulating Tryptophan Metabolism through the Microbiota-Gut-Brain Axis.
Curcumin-loaded nanoscale coordination polymers for ROS scavenging and anti-inflammatory therapy in atherosclerosis.
Rutin alleviates preoperative anxiety stress-induced persistent postoperative pain by inhibiting microglia-mediated abnormal synaptic engulfment in the spinal cord dorsal horn.
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
LCCPs causes cartilage damage and exacerbates osteoarthritis by inducing necroptosis of chondrocytes.
Human amniotic mesenchymal stem cell-derived exosome inhibits ferroptosis through the suppression of JNK/MAPK-mediated EGR1 expression in spontaneous intracerebral hemorrhage.
Porphyromonas gingivalis-Lipopolysaccharide Induced Gingival Fibroblasts Trained Immunity Sustains Inflammation in Periodontitis.
Significance of integrated clinical and proteomic characteristics analysis for pathogenesis and management of Crohn's disease with concomitant psoriasis.
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Elimination of a neutrophil Pad4 byproduct restores stem cell-mediated bone regeneration in hyperglycemia.
Multifunctional Inorganic-Nanosheets-Based Nanohydrogel for Periodontal Bone Regeneration via Antibacterial and Anti-Ferroptotic Immunomodulation.
QuYuShengXin formula reshapes bile-acid-mediated macrophage polarization in the treatment of ulcerative colitis.
Cellular senescence of RANKL(+) osteoblasts and Th17 cells in severe periodontitis with occlusal trauma.
Cu/Zn/histidine supramolecular assemblies with optimized Cu catalytic sites as an alternative of superoxide dismutase.
Chrysin Improves Cognitive Dysfunction in Rats with Intracerebral Hemorrhage by Regulating the Nrf2/GPX4 Pathway to Inhibit Ferroptosis.
Mechanism of the traditional Chinese medicine SMBJ alleviates diabetes mellitus-induced Leydig cell dysfunction in rats testes.
Role of intestinal SCFAs homeostasis in the hepatoprotective effect of Clostridium butyricum in T2DM.
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
PDGFR-α Mediated the Neuroinflammation and Autophagy via the JAK2/STAT3 Signaling Pathway Contributing to Depression-Like Behaviors in Myofascial Pain Syndrome Rats.
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
Integrating Serum Pharmacochemistry With Network Pharmacology to Elucidate the Mechanism of Wushen Decoction in the Prevention and Treatment of Lower Extremity Erysipelas.
Auricular Transcutaneous Vagus Nerve Stimulation Enhances Post-Stroke Neurological and Cognitive Recovery in Mice by Suppressing Ferroptosis Through α7 Nicotinic Acetylcholine Receptor Activation.
Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing.
A dual gene-activated dermal scaffolds loaded with nanocomposite particles expressing of VEGF and aFGF: Promoting wound healing by early vascularization.
Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway.
Resveratrol Promotes Wound Healing by Enhancing Angiogenesis via Inhibition of Ferroptosis.
Targeting inflammation and necroptosis in diabetic kidney disease: A novel approach via PPARα modulation.
MiR-29a-3p ameliorate behavioral deficiency in hypoxia-ischemia brain damage in neonatal mice by inhibiting BTG2.
COP1 Overexpression Attenuates Nociceptive Behaviors and Neuroinflammation in Cancer-Induced Bone Pain by Suppressing c/EBPβ.
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Bio-Mimicking Nanoparticle System Facilitates Sonodynamic-Mediated Clearance of Extensively Drug-Resistant Bacteria.
Cadmium exposure induces Leydig cell injury via necroptosis caused by oxidative stress and TNF-α/TNFR1 signaling.
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
Extracellular HSP70 facilitated β-glucan induced trained immunity in macrophages to suppress sepsis via TLR2-NF-κB axis.
MOF-818 Nanozyme Suppresses Calcium Oxalate Kidney Stones by Alleviating Oxidative Stress and Inflammatory Injury.
Trojan Horse-Like Biohybrid Nanozyme for Ameliorating Liver Ischemia-Reperfusion Injury.
Targeting the NF-κB p65-MMP28 axis: Wogonoside as a novel therapeutic agent for attenuating podocyte injury in diabetic nephropathy.
Baicalin, Amoxicillin, and Probenecid Provide Protection in Mice Against Glaesserella parasuis Challenge.
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
DKS26 Alleviates Ischemia-Reperfusion Injury-Induced Acute Kidney Injury by Stabilizing Vitamin D Receptors to Inhibit the Inflammatory Pathway of NF-κB P65.
Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the Brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD Mice.
Chronic exposure to liquid crystal monomer EBCN at environmentally relevant concentrations induces testicular dysfunction via the gut-testis axis.
Brown adipose tissue transplantation ameliorates hindlimb ischemic damage in diabetic mice.
Diallyl Trisulfide Attenuates Ischemia-Reperfusion-Induced ER Stress and Kidney Dysfunction in Aged Female Mice.
Identification of biomarkers associated with pathological tumor staging and their utility in the diagnosis and prognosis of prostate cancer.
Electroacupuncture Neural Stimulation Mitigates Bladder Dysfunction and Mechanical Allodynia in Cyclophosphamide Induced Cystitis through Downregulation of the BDNF-TrkB Signaling Pathway.
P2Y6R Inhibition Induces Microglial M2 Polarization by Promoting PINK1/Parkin-Dependent Mitophagy After Spinal Cord Injury.
Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation.
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis.
Integrated network pharmacology and experimental validation to elucidate the mechanism of celastrol in mitigating sepsis-induced acute lung injury in mice.
Effect of COL11A1 on oral squamous cell carcinoma.
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
C18:0 GM3 ganglioside's efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation.
Gallic Acid and Taurine Attenuate Thiamethoxam-Induced Hepatotoxicity in Rats by Modulating SIRT-1/PGC-1α, NF-κB/iNOS, and p53/Bax/Caspase-3 Pathways.
Stem cell secretome armed magneto-actuated micromotors as spatio-temporal manipulators for wound healing acceleration.
High-Fructose High-Fat Diet Renders the Retina More Susceptible to Blue Light Photodamage in Mice.
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Normal stress on surface of mesenchymal stem cells boosts extracellular vesicle secretion and regenerative bioactivity.
A Novel Effect of Id2 in Microglia TNFα Regulation.
High glucose enhances malignant progression of MDA-MB-231 cells through cumulative effect.
Supramolecular nanoparticle loaded with bilirubin enhances cartilage protection and alleviates osteoarthritis via modulating oxidative stress and inflammatory responses.
Short-term exposure to low doses of aflatoxin B1 aggravates nonalcoholic steatohepatitis by TLR4-mediated necroptosis.
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure.
Tanshinone IIA, a component of Salvia miltiorrhiza Bunge, attenuated sepsis-induced liver injury via the SIRT1/Sestrin2/HO-1 signaling pathway.
Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges.
In situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment.
IL-17A exacerbates synovial inflammation in osteoarthritis via activation of endoplasmic reticulum stress.
tRNA-derived fragment 3031B regulates human anterior cruciate ligament cell proliferation and survival by targeting RELA.
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
Exploring the potential anti-COPD ingredients and mechanisms of the Qingfei decoction based on UHPLC-HRMS, network pharmacology and transcriptomic analysis.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Subconjunctival injection of microcrystalline prodrug of dexamethasone for long-acting anti-inflammation after phacoemulsification surgery.
Microglia phagocytosis of PNNs mediates PV-positive interneuron dysfunction and associated gamma oscillations in neuroinflammation-induced cognitive impairment in mice.
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
Long-chain chlorinated paraffins (LCCPs) exposure causes senescence and inflammatory damage in cardiomyocytes.
Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling.
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice.
Ferroptosis Induces gut microbiota and metabolic dysbiosis in Collagen-Induced arthritis mice via PAD4 enzyme.
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Blocking the p38 MAPK Signaling Pathway in the Rat Hippocampus Alleviates the Depressive-like Behavior Induced by Spinal Cord Injury.
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Eu-Doped TiO(2) Coatings via One-Step In Situ Preparation Enhance Macrophage Polarization and Osseointegration of Implants.
Analysis of ferroptosis-related genes in cerebral ischemic stroke via immune infiltration and single-cell RNA-sequencing.
Toll-like receptor 4 inhibition by pyridostigmine is associated with a reduction in hypertension and inflammation in rat models of preeclampsia.
Spinal AT1R contributes to neuroinflammation and neuropathic pain via NOX2-dependent redox signaling in microglia.
Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice.
Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway.
Functionalized hydrocaffeic acid-chitosan/EGTA hydrogel rescues mitochondrial dysfunction for immunomodulation and joint repair in rheumatoid arthritis.
Herb-based multicomponent carrier-free hydrogel with antipyretic and anti-inflammatory dual effects by regulating MAPK and NF-κB signaling pathway.
Bovine tubulin cofactor D (TBCD) disrupts tubulin dimers and inhibits tumor growth via the TNF-α signaling pathways-mediated ROS production.
Structural characterisation of a polysaccharide from Sanghuangporus vaninii and its synergistic anti-hepatocellular carcinoma activity in combination with sorafenib.
Tryptophan derivatives as non-invasive diagnostic indicators for obesity-related MASLD in children and adolescents.
Pyridostigmine attenuates placental-ischemia-upregulated placental angiotensin II type 1 receptor in rats.
Pyruvate kinase M2 (PKM2) regulates rheumatoid arthritis by mediating glycolysis reprogramming through the Akt/mTOR pathway.
E3 ubiquitin ligase Pellino1 suppresses acinar cell necroptosis and alleviates severe acute pancreatitis by promoting ubiquitin-dependent receptor-interacting protein kinase 3 (RIP3) degradation.
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Treadmill exercise ameliorates atherogenesis and vascular inflammation in ApoE(-/-) mice via circulating exosome-derived let-7c-5p.
Adipose-Derived Mesenchymal Stem Cells Improve Acute Liver Injury: A Mechanistic Study Based on the TLR4/MyD88/NF-κB Pathway.
Sirtuin 3 promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating macrophage polarization under high glucose.
The ZFP36-FTO axis is a key regulator of macrophage activation and a druggable therapeutic target of sepsis.
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
Toll-Like Receptor 7 Promotes Periodontal Inflammation and Alveolar Bone Resorption Through the NF-κB Signaling Pathway.
Mechanistic Insights into HOTAIR-Driven ADAM17/NF-Κb Activation and Endothelial Dysfunction in LPS-Challenged HUVECs.
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
An's anorectal fumigation lotion for nuclear factor kappa-B pathway-targeted treatment of inflammatory mixed hemorrhoids.
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy.
Exploration of the Therapeutic Time Window for Thrombectomy in Rat Models of Middle Cerebral Artery Ischemia-Reperfusion.
Targeting CDK1 inhibits Golgi apparatus stress-mediated neuroinflammation and neuronal apoptosis after intracerebral hemorrhage by modulating GRASP55 phosphorylation.
Decreased excitatory and increased inhibitory transmission in the hippocampal CA1 drive neuroinflammation-induced cognitive impairments in mice.
T-2 Toxin-Induced Hepatotoxicity in HepG2 Cells Involves the Inflammatory and Nrf2/HO-1 Pathways.
An Olsalazine-Loaded Hollow Mesoporous Prussian Blue/Polydopamine Nanozyme Alleviates Anxiety/Depression-like Behavior and Enhances Brain Neural Activity in Colitis Mice.
DEK Interacts with IRE1α to Modulate Endoplasmic Reticulum Stress in Deoxynivalenol-Induced Intestinal Inflammation.
Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice.
Yuye Jinhua Qingre Tablets Attenuate Acute Pharyngitis by inhibiting the Complement Cascade and C5a/C5aR1 Axis.
Hybrid molecule SA-10 and its PLGA nanosuspension protect human and rodent retinal ganglion cells against neuronal injury.
2-aminoethoxydiphenylborane intervenes intracellular calcium signaling and attenuates myocardial ischemia-reperfusion injury in mice through ITPR1/MCU pathway.
Hydrogen protects against autoimmune myocarditis by inhibiting necroptosis via the TNF/TNFR1 signalling pathway.
Hepatoprotective effects of polysaccharide from Morchella esculenta are associated with activation of the AMPK/Sirt1 signaling pathway in mice with NAFLD.
Injectable DMM/GelMA hydrogel for diabetic wound healing via regulating mitochondrial metabolism and macrophage repolarization.
Identifying ENO1 as a protein target of chlorogenic acid to inhibit cellular senescence and prevent skin photoaging in mice.
Tmco1-Deficient Mice Exhibit a High Incidence of Otitis Media Associated with Impaired Bone Homeostasis in the Middle Ear.
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
A Smart MMP-9-responsive Hydrogel Releasing M2 Macrophage-derived Exosomes for Diabetic Wound Healing.
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
A novel histone deacetylase inhibitor protects the blood-brain barrier by regulating NF-κB and Nrf2 signaling pathways in OGD/R injury.
Network Pharmacology and In Vitro Experimental Validation Reveal the Anti-Inflammatory and Anti-Apoptotic Effects of Lotus Leaf Extract in Treating Inflammatory Diarrhea in Pigs.
Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier.
Wogonoside ameliorates oxidative damage in tubular epithelial cells of diabetic nephropathy by modulating the HNF4A-NRF2 axis.
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
Chitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization.
Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway.
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Run-Mu-Ling Granules Mitigate Ocular Surface Inflammatory Injury Associated with Dry Eye by Suppressing the NLRP3/GSDMD-Mediated Pyroptosis Pathway.
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation.
Celecoxib ameliorates diabetic sarcopenia by inhibiting inflammation, stress response, mitochondrial dysfunction, and subsequent activation of the protein degradation systems.
Fibroblasts facilitate lymphatic vessel formation in transplanted heart.
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury.
Mechanism of Lian Hua Qing Wen capsules regulates the inflammatory response caused by M(1) macrophage based on cellular experiments and computer simulations.
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
oHSV2-mGM repolarizes TAMs and cooperates with αPD1 to reprogram the immune microenvironment of residual cancer after radiofrequency ablation.
Geniposide dosage and administration time: Balancing therapeutic benefits and adverse reactions in liver disease treatment.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Effects of thyroid hormone on monochromatic light combinations mediate skeletal muscle fiber pattern in broilers.
Transferrin-Modified Carprofen Platinum(IV) Nanoparticles as Antimetastasis Agents with Tumor Targeting, Inflammation Inhibition, Epithelial-Mesenchymal Transition Suppression, and Immune Activation Properties.
Gabapentin alleviates peripheral nerve sensitization induced by inflammatory arthritis via ionotropic glutamate receptor NR2B subunit.
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Integrating metabolomics and network pharmacology analysis to explore mechanism of Pueraria lobata against pulmonary fibrosis: Involvement of arginine metabolism pathway.
Magnolol Inhibits High Fructose-Induced Podocyte Inflammation via Downregulation of TKFC/Sp1/HDAC4/Notch1 Activation.
Oxytocin attenuates neuroinflammation-induced anxiety through restoration of excitation and inhibition balance in the anterior cingulate cortex in mice.
Placental ischemia-upregulated angiotensin II type 1 receptor in hypothalamic paraventricular nucleus contributes to hypertension in rat.
Sodium-Glucose Co-Transporter-2 Inhibitor Empagliflozin Attenuates Sorafenib-Induced Myocardial Inflammation and Toxicity.
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
SIRT2 regulates high mobility group protein B1 nucleoplasmic shuttle and degradation via deacetylation in microglia.
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction.
Oxymatrine alleviates NSAID-associated small bowel mucosal injury by regulating MIP-1/CCR1 signalling and gut microbiota.
Leukocyte Platelet-Rich Plasma-Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization.
Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth.
Nobiletin attenuates alcohol-related liver disease by inhibting gut-liver inflammation and gut microbiota disturbance in mice.
Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains.
Dingxian pill alleviates hippocampal neuronal apoptosis in epileptic mice through TNF-α/TNFR1 signaling pathway inhibition.
Gut microbial and metabolomics profiles reveal the potential mechanism of fecal microbiota transplantation in modulating the progression of colitis-associated colorectal cancer in mice.
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Pesticide metabolite 3, 5, 6-trichloro-2-pyridinol causes massive damage to the cochlea resulting in hearing loss in adult mice.
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
The association between endothelial function and autoimmune thyroiditis induced by iodine excess.
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
Supercritical CO(2) fluid extract from Stellariae Radix ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis by inhibit M1 macrophages polarization via AMPK activation.
The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury.
Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury.
YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Unmasking the dynamics of Mycoplasma gallisepticum: deciphering HD11 macrophage polarization for innovative infection control strategies.
MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.
Manual acupuncture ameliorates inflammatory pain by upregulating adenosine A(3) receptor in complete Freund's adjuvant-induced arthritis rats.
Purinergic Astrocyte Signaling Driven by TNF-α After Cannabidiol Administration Restores Normal Synaptic Remodeling Following Traumatic Brain Injury.
IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis.
Electroacupuncture modulates the TLR4-NF-κB inflammatory signaling pathway to attenuate ocular surface inflammation in dry eyes of type 2 diabetic rats.
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury.
Shengjihuayu formula ameliorates the oxidative injury in human keratinocytes via blocking JNK/c-Jun/MMPs signaling pathway.
Mechanic study based on untargeted metabolomics of Pi-pa-run-fei-tang on pepper combined with ammonia induced chronic cough model mice.
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Resveratrol attenuates inflammation and fibrosis in rheumatoid arthritis-associated interstitial lung disease via the AKT/TMEM175 pathway.
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Self-assembly of PEG-PPS polymers and LL-37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic wound healing.
Single-Cell Transcriptomics Reveals the Ameliorative Effect of Oridonin on Septic Liver Injury.
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Oral delivery of miR-146a-5p overexpression plasmid-loaded Pickering double emulsion modulates intestinal inflammation and the gut microbe.
Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway.
S100A9(-/-) alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFκB signaling axis.
Nrf-2/ROS/NF-κB pathway is modulated by cynarin in human mesenchymal stem cells in vitro from ankylosing spondylitis.
Novel mechanism of Clostridium butyricum alleviated coprophagy prevention-induced intestinal inflammation in rabbit.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
IL-22 promotes occludin expression by activating autophagy and treats ulcerative colitis.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Dual cross-linked self-healing hydrogel enhanced by dopamine nanoparticles and raffinose for wound healing.
Scutellarin alleviates microglia-mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathway.
Gut microbiota mediates the protective effects of β-hydroxybutyrate against cisplatin-induced acute kidney injury.
Associations of cold-inducible RNA-binding protein with bacterial load, proinflammatory cytokines and mortality from pneumonia.
Development and Investigation of an Innovative 3D Biohybrid Based on Collagen and Silk Sericin Enriched with Flavonoids for Potential Wound Healing Applications.
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis.
Cancerous Conditions Accelerate the Aging of Skeletal Muscle via Mitochondrial DNA Damage.
Evaluation of Cross-Talk and Alleviate Potential of Cytotoxic Factors Induced by Deoxynivalenol in IPEC-J2 Cells Interference with Curcumin.
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
A bioenergetically-active ploy (glycerol sebacate)-based multiblock hydrogel improved diabetic wound healing through revitalizing mitochondrial metabolism.
The role of serum/glucocorticoid-regulated kinase 1 in brain function following cerebral ischemia.
Macrophage ATG16L1 expression suppresses metabolic dysfunction-associated steatohepatitis progression by promoting lipophagy.
Protective Role of MerTK in Diabetic Peripheral Neuropathy via Inhibition of the NF-κB Signaling Pathway.
Disulfiram downregulates ferredoxin 1 to maintain copper homeostasis and inhibit inflammation in cerebral ischemia/reperfusion injury.
Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes.
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
NADase CD38 is a key determinant of ovarian aging.
CircIRAK3 exerts negative feedback regulation on inflammation by binding to HNRNP U and destabilizing proinflammatory cytokine mRNA in osteoarthritis and chondrogenesis.
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling.
Pyrolae herba alleviates cognitive impairment via hippocampal TREM2 signaling modulating neuroinflammation and neurogenesis in lipopolysaccharide-treated mice.
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) alleviates cerebral ischemia/reperfusion injury in mice by regulating microglia polarization via A20/NF-κB pathway.
Preventive effect of low-carbohydrate high-fat dietary pattern on liver disease caused by alcohol consumption via a 6pgd-involved mechanism in mice.
Zinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4/NF-κB pathway in meat ducks.
Increased Circulating IL-32 Is Associated With Placenta Macrophage-derived IL-32 and Gestational Diabetes Mellitus.
Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation.
Effect of Infliximab on Radiation-Induced Submandibular Gland Dysfunction in Rats.
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion.
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Fibroblast growth factor 21 alleviates unilateral ureteral obstruction-induced renal fibrosis by inhibiting Wnt/β-catenin signaling pathway.
Early life stress enhances the susceptibility to depression and interferes with neuroplasticity in the hippocampus of adolescent mice via regulating miR-34c-5p/SYT1 axis.
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Rosavin Alleviates LPS-Induced Acute Lung Injure by Modulating the TLR-4/NF-κB/MAPK Singnaling Pathways.
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Suppressing inflammatory signals and apoptosis-linked sphingolipid metabolism underlies therapeutic potential of Qing-Jin-Hua-Tan decoction against chronic obstructive pulmonary disease.
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
Exploring the therapeutic potential of puerarin on intervertebral disc degeneration by regulating apoptosis of nucleus pulposus cells.
Hypothermic oxygenated perfusion inhibits CLIP1-mediated TIRAP ubiquitination via TFPI2 to reduce ischemia‒reperfusion injury of the fatty liver.
Amitraz mechanisms of cytotoxicity in a characterized SH-SY5Y cells spheroid model.
TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway.
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
An injectable self-lubricating supramolecular polymer hydrogel loaded with platelet lysate to boost osteoarthritis treatment.
Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly.
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice.
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
Breaking the boundaries of wound closure: A novel polyurethane tissue adhesive with enhanced healing properties.
Toralactone alleviates cisplatin-induced acute kidney injury by modulating the gut microbiota-renal axis.
Role of MYO1F in neutrophil and macrophage recruitment and pro-inflammatory cytokine production in Aspergillus fumigatus keratitis.
Cardioprotective effect of Saussurea involucrata injection against Doxorubicin-induced cardiotoxicity by network pharmacology analysis and experimental verification.
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
ATP citrate lyase ablation hampers exocrine regeneration via TLR4/NF-kappaB signaling after acute pancreatitis in mice.
Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.
Discovery of the synergy between sulindac and NO expands the application of NSAIDs in cardiac complications.
Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice.
Exosomes from human bone marrow MSCs alleviate PD-1/PD-L1 inhibitor-induced myocardial injury in melanoma mice by regulating macrophage polarization and pyroptosis.
A New Modulator of Neuroinflammation in Diabetic Retinopathy: USP25.
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-κB/MAPK pathways via binding to TAK1.
SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure.
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Exploring the mechanism of Lianhuaqingwen (LHQW) in treating chronic bronchitis based on network pharmacology and experimental validation.
IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction.
GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease.
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function.
Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway.
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Neuroprotective effect of tanshinone IIA-modified mesenchymal stem cells in a lipopolysaccharide-induced neuroinflammation model.
Biomimetic nanoparticles for effective Celastrol delivery to targeted treatment of rheumatoid arthritis through the ROS-NF-κB inflammasome axis.
Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway.
Muscone inhibits the progression of atherosclerotic plaques in mice aorta by inhibiting the NF-κB/p65 pathway.
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis.
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Increased serum levels of high-mobility group box 1 protein and the location characteristics in the patients of intracranial aneurysms.
Integrated Proteomic and Phosphoproteomic Analysis of the Hippocampus in a Mouse Model of Early Life Inflammation.
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
Curcumin Alleviates Epidermal Psoriasis-Like Dermatitis and IL-6/STAT3 Pathway of Mice.
Characterisation of macrophage infiltration and polarisation based on integrated transcriptomic and histological analyses in Primary Sjögren's syndrome.
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Diabetes mellitus induces a novel inflammatory network involving cancer progression: Insights from bioinformatic analysis and in vitro validation.
Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis in atherogenic diet-fed ApoE (-/-) knockout mice.
Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model.
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate.
Puerarin inhibits inflammation and lipid accumulation in alcoholic liver disease through regulating MMP8.
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Rescuing Nucleus Pulposus Cells From Senescence via Dual-Functional Greigite Nanozyme to Alleviate Intervertebral Disc Degeneration.
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Dandelion Polysaccharides Ameliorate High-Fat-Diet-Induced Atherosclerosis in Mice through Antioxidant and Anti-Inflammatory Capabilities.
Combining idebenone and rosuvastatin prevents atherosclerosis by suppressing oxidative stress and NLRP3 inflammasome activation.
Single-cell RNA sequencing reveals the effects of capsaicin in the treatment of sepsis-induced liver injury.
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis.
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Mediation of endoplasmic reticulum stress and NF-κB signaling pathway in DINP-exacerbated allergic asthma: A toxicological study with Balb/c mice.
Liraglutide intervention improves high-glucose-induced reactive gliosis of Müller cells and ECM dysregulation.
Paneth cells protect intestinal stem cell niche to alleviate deoxynivalenol-induced intestinal injury.
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Exploring the therapeutic potential of a nano micelle containing a carbon monoxide-releasing molecule for metabolic-associated fatty liver disease by modulating hypoxia-inducible factor-1α.
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Sleep deprivation alleviates depression-like behaviors in mice via inhibiting immune and inflammatory pathways and improving neuroplasticity.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Polymeric nano-micelle of carbon monoxide donor SMA/CORM2 ameliorates acetaminophen-induced liver injury via suppressing HMGB1/TLR4 signaling pathway.
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression.
Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury.
Enoxaparin sodium bone cement displays local anti-inflammatory effects by regulating the expression of IL-6 and TNF-α.
Investigation of macrophage polarization in herniated nucleus pulposus of patients with lumbar intervertebral disc herniation.
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease.
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Thymopentin (TP-5) prevents lipopolysaccharide-induced neuroinflammation and dopaminergic neuron injury by inhibiting the NF-κB/NLRP3 signaling pathway.
A systematic pharmacology-based in vivo study to reveal the effective mechanism of Yupingfeng in asthma treatment.
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Protocol for preparation of a photo-triggering double cross-linked adhesive, antibacterial, and biocompatible hydrogel for wound healing.
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
TFP5 attenuates cyclin-dependent kinase 5-mediated islet β-cell damage in diabetes.
Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries.
Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms.
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Pulsatilla chinensis saponins ameliorated murine depression by inhibiting intestinal inflammation mediated IDO1 overexpression and rebalancing tryptophan metabolism.
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.
Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.
Inflammatory mechanisms of Ginkgo Biloba extract in improving memory functions through lncRNA-COX2/NF-κB pathway in mice with status epilepticus.
Early brainstem hemorrhage progression: multi-sequence magnetic resonance imaging and histopathology.
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage.
Low-Dose Sodium Salicylate Promotes Ovulation by Regulating Steroids via CYP17A1.
Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation.
Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging.
Identification of Senescent Cells in Peri-Implantitis and Prevention of Mini-Implant Loss Using Senolytics.
Protein kinase D1 promotes the survival of random-pattern skin flaps in rats.
Osteopontin associates with brain T(RM)-cell transcriptome and compartmentalization in donors with and without multiple sclerosis.
IRF5 knockdown reverses TDP-related phenotypes partially by increasing TBK1 expression.
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease.
Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy.
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
TNFR2 is a potent prognostic biomarker for post-transplant lung metastasis in patients with hepatocellular carcinoma.
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Peroxiredoxins and Hypoxia-Inducible Factor-1α in Duodenal Tissue: Emerging Factors in the Pathophysiology of Pediatric Celiac Disease Patients.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
LncRNA GAS5 downregulates NLRP3 inflammasome activation-mediated pyroptosis in sepsis-induced myocardial injury by targeting SIRT3/AMPKα.
Thyroid-stimulating hormone may participate in insulin resistance by activating toll-like receptor 4 in liver tissues of subclinical hypothyroid rats.
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
RNA sequencing reveals the mechanism of FTO in inhibiting inflammation and excessive proliferation of lipopolysaccharide-induced human glomerular mesangial cells.
Hydroxypropyl-β-cyclodextrin inhibits the development of triple negative breast cancer by enhancing antitumor immunity.
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma.
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264.7 macrophages.
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
Ginsenoside Rb1 inhibits ferroptosis to ameliorate hypoxic-ischemic brain damage in neonatal rats.
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
Biocompatibility and efficacy of prostatic urethral lift in benign prostate hyperplasia: an in vivo and in vitro study.
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway.
Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus.
Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis.
SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction.
Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol.
Blood serum analysis: A modified sandwich enzyme-linked immunosorbent assay protocol.
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Coprophagy Prevention Affects the Reproductive Performance in New Zealand White Rabbits Is Mediated through Nox4-ROS-NFκB Pathway.
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.
Metformin Improves the Prognosis of Adult Mice with Sepsis-Associated Encephalopathy Better than That of Aged Mice.
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation.
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis.
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation.
Roxadustat, a Hypoxia-Inducible Factor 1α Activator, Attenuates Both Long- and Short-Term Alcohol-Induced Alcoholic Liver Disease.
Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration in a Spontaneous Polygenic Model of Inherited Retinal Dystrophy.
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of Action.
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination.
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
β-Lapachone, an NQO1 activator, alleviates diabetic cardiomyopathy by regulating antioxidant ability and mitochondrial function.
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
The role of proteoglycan form of DMP1 in cranial repair.
Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes.
Synergistic anti-inflammatory effects of peimine, peiminine, and forsythoside a combination on LPS-induced acute lung injury by inhibition of the IL-17-NF-κB/MAPK pathway activation.
Biomechanically-Adapted Immunohydrogels Reconstructing Myelin Sheath for Peripheral Nerve Regeneration.
Transcriptomic Analysis Reveals Lactobacillus reuteri Alleviating Alcohol-Induced Liver Injury in Mice by Enhancing the Farnesoid X Receptor Signaling Pathway.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice.
Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling.
miR-146a-5p promotes epithelium regeneration against LPS-induced inflammatory injury via targeting TAB1/TAK1/NF-κB signaling pathway.
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.
Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition.
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Desmethylbellidifolin Attenuates Dextran Sulfate Sodium-Induced Colitis: Impact on Intestinal Barrier, Intestinal Inflammation and Gut Microbiota.
Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.
MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice.
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome.
Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Reduced inhibition underlies early life LPS exposure induced-cognitive impairment: Prevention by environmental enrichment.
A photo-triggering double cross-linked adhesive, antibacterial, and biocompatible hydrogel for wound healing.
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
Hadh deficiency induced oligoasthenoteratozoospermia through the TNF-α/Bcl-2 pathway in male mice.
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice.
In vitro and in vivo biological evaluation of newly synthesized multi-target 20(R)-panaxadiol derivatives for treating Alzheimer's disease.
Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes.
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
High triiodothyronine levels induce myocardial hypertrophy via BAFF overexpression.
Intestinal Klebsiella pneumoniae Contributes to Pneumonia by Synthesizing Glutamine in Multiple Myeloma.
Vasoactive Effects of Chronic Treatment with Fructose and Slow-Releasing H(2)S Donor GYY-4137 in Spontaneously Hypertensive Rats: The Role of Nitroso and Sulfide Signalization.
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis.
Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice.
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.
Knockout of Bruton's tyrosine kinase in macrophages attenuates diabetic nephropathy in streptozotocin-induced mice.
Peroxisome Proliferator-Activated Receptor-Gamma Reduces ER Stress and Inflammation via Targeting NGBR Expression.
Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid.
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Ibudilast Attenuates Folic Acid-Induced Acute Kidney Injury by Blocking Pyroptosis Through TLR4-Mediated NF-κB and MAPK Signaling Pathways.
Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.
Activation of the cGAS-STING signaling pathway in adenomyosis patients.
The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation.
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
An experimental model of the epithelial to mesenchymal transition and pro-fibrogenesis in urothelial cells related to bladder pain syndrome/interstitial cystitis.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer.
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis.
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway.
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
The effects of BMMSC treatment on lung tissue degeneration in elderly macaques.
Excessive downhill training leads to early onset of knee osteoarthritis.
Polysaccharide MCP extracted from Morchella esculenta reduces atherosclerosis in LDLR-deficient mice.
Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model.
WITHDRAWN: Immunohistochemical study of inflammatory responses in septa arising from type I intestinal atresia.
Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the gut microbiota.
Suppression of adenosine A(2a) receptors alleviates bladder overactivity and hyperalgesia in cyclophosphamide-induced cystitis by inhibiting TRPV1.
Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in goat male germline stem cells.
Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.
Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma.
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation.
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa.
Platelet membrane-camouflaged silver metal-organic framework drug system against infections caused by methicillin-resistant Staphylococcus aureus.
Nr2e1 deficiency aggravates insulin resistance and chronic inflammation of visceral adipose tissues in a diet-induced obese mice model.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Inhibition of Matrix Metalloproteinase with BB-94 Protects against Caerulein-Induced Pancreatitis via Modulating Neutrophil and Macrophage Activation.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma.
Role of Endoplasmic Reticulum Stress in Otitis Media.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
High Dimensional Mass Cytometry Analysis Reveals Characteristics of the Immunosuppressive Microenvironment in Diffuse Astrocytomas.
Ameliorating Effect of Pentadecapeptide Derived from Cyclina sinensis on Cyclophosphamide-Induced Nephrotoxicity.
Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems.
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex.
Activated microglia-derived macrophage-like cells exacerbate brain edema after ischemic stroke correlate with astrocytic expression of aquaporin-4 and interleukin-1 alpha release.
BET Protein Inhibition Prolongs Cardiac Transplant Survival via Enhanced Myocardial Autophagy.
Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose.
Antiviral mechanism of carvacrol on HSV-2 infectivity through inhibition of RIP3-mediated programmed cell necrosis pathway and ubiquitin-proteasome system in BSC-1 cells.
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats.
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Myeloid-specific dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage.
Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury.
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts.
Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway.
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Polysaccharides from the Fleshy Fruits of Camellia oleifera Attenuate the Kidney Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response.
Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice.
Osteocytic connexin 43 channels affect fracture healing.
miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN.
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.
Highly Acylated Anthocyanins from Purple Sweet Potato ( Ipomoea batatas L.) Alleviate Hyperuricemia and Kidney Inflammation in Hyperuricemic Mice: Possible Attenuation Effects on Allopurinol.
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro.
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin.
The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss.
IL-6 induced M1 type macrophage polarization increases radiosensitivity in HPV positive head and neck cancer.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice.
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Gene transfer of a naked plasmid (pUDK-HGF) encoding human hepatocyte growth factor attenuates skin/muscle incision and retraction-induced chronic post-surgical pain in rats.
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
IGF1 affects macrophage invasion and activation and TNF-α production in the sciatic nerves of female SOD1G93A mice.
Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling.
α-catenin SUMOylation increases IκBα stability and inhibits breast cancer progression.
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer.
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer.
Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice.
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus.
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS).
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Neat1-miRNA204-5p-PI3K-AKT axis as a potential mechanism for photodynamic therapy treated colitis in mice.
Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice.
lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma.
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
One-Shot Dual-Code Immunotargeting for Ultra-Sensitive Tumor Necrosis Factor-α Nanosensors by 3D Enhanced Dark-Field Super-Resolution Microscopy.
Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Dynamic changes of α-melanocyte-stimulating hormone levels in the serum of patients with craniocerebral trauma.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Rapamycin suppresses Aβ(25-35)- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation.
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1(G93A) ALS Mice.
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway.
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.
Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat.
The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure.
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
MiR-152 reduces human umbilical vein endothelial cell proliferation and migration by targeting ADAM17.
Yue S, Xing H, Du X, Wang Y, Qin R, He J, Yu J, Zhangsun D, Craik DJ, McIntosh JM, Wu Y, Zhu X, Luo S
International journal of biological macromolecules 2026 Mar;349:150933
International journal of biological macromolecules 2026 Mar;349:150933
Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.
Qiao Q, Gong Q, Li N, Sun H, Ru X, Mu N, Chen B, Li W, Chen T, Feng H, Chen Y, Cheng H
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Mar;23(2):e00868
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Mar;23(2):e00868
Protocatechualdehyde-functionalized BMSC-derived exosomes orchestrate calcium signaling in the immunoinflammatory microenvironment to promote periodontal regeneration.
Fan L, Wang T, Ma M, Wang Y, Wang X, Tang X, Ma Y, Gu Z, Hao Z
Journal of nanobiotechnology 2026 Mar 7;24(1)
Journal of nanobiotechnology 2026 Mar 7;24(1)
CSF1 regulates inflammation and apoptosis in intervertebral disc degeneration.
Zhang F, Wu W, Yuan Y, Wang Y, Zhang W
Scientific reports 2026 Mar 30;16(1)
Scientific reports 2026 Mar 30;16(1)
CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation.
Xu N, Yu B, Li Y, Yang Y, Wang Y, Fang L, Wu H, Luan Y, Yin C
Cellular & molecular biology letters 2026 Mar 25;31(1)
Cellular & molecular biology letters 2026 Mar 25;31(1)
Combined single-cell transcriptome and immune repertoire analysis reveals hepatic and renal immune injury by heat stroke.
Zhang M, Wang B, Sun D, Chen X, Zhou Y, Yao J, Du L, Zhang Z, Li H, Qu Z, Chen L, Luo Q, Zhang J, Jin X, Cheng X, Niu J, Xing Q, Tan X, Wang T, Liu J, Li L, Song Q, Chen X, Chen Y
JCI insight 2026 Mar 23;11(6)
JCI insight 2026 Mar 23;11(6)
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Wu J, Ge Y, Zhang L, Huang J, Huang N, Luo Y
Stem cell research & therapy 2026 Mar 17;17(1)
Stem cell research & therapy 2026 Mar 17;17(1)
Procyanidin capsules attenuate PI3K/AKT-mediated mitochondrial dysfunction and accelerate skin wound healing in diabetic mice.
Ping Y, Wang J, Wei S, Tong W, Li W, Ren J, Wang S, Yao X, Zheng L, Cao Z, Yang D, Wen C, Huang S, Zhao S
Materials today. Bio 2026 Jun;38:103029
Materials today. Bio 2026 Jun;38:103029
Shaoyao Gancao Decoction ameliorates rheumatoid arthritis via inhibition of TNF-α/NF-κB signaling pathway.
Zhao Y, Gao K, Zhao Y, Feng C, Liu H, Shi L, Sun W
Journal of ethnopharmacology 2026 Jun 28;365:121552
Journal of ethnopharmacology 2026 Jun 28;365:121552
Gastrin releasing peptide receptor antagonism in the paraventricular nucleus exerts antihypertensive effects in 2K1C rats.
Wang XM, Liu JJ, Wang YP, Bai C, Issotina Zibrila A, Xia WJ, Yang RN, Kang YM, Yu XJ
Toxicology and applied pharmacology 2026 Jan;506:117620
Toxicology and applied pharmacology 2026 Jan;506:117620
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
Yu S, Cheng Q, Yu Q, Cui Z, Chen H, Wu S, Jin Y, Wang Y, Li M, Lu Z
Aging cell 2026 Jan;25(1):e70350
Aging cell 2026 Jan;25(1):e70350
MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury.
Li X, Zhu Z, Wang Y, Wan H, Wang Z, Qiao W
Immunity, inflammation and disease 2026 Jan;14(1):e70334
Immunity, inflammation and disease 2026 Jan;14(1):e70334
Low-dose urapidil mitigates renal ischemia-reperfusion injury through matrix metalloproteinase-9 inhibition and anti-inflammatory effects.
Sarıtaş H, Sarıtaş ZK, Keskin HA, Görücü Özbek F, Bülbül A, Koç Y, Erdoğan BG, Danacı Z, Demireller B
Science progress 2026 Jan-Mar;109(1):368504261438886
Science progress 2026 Jan-Mar;109(1):368504261438886
Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
Wang MN, Zhou YX, Zhao YX, Tan JW, Sang X
Molecular pain 2026 Jan-Dec;22:17448069251413879
Molecular pain 2026 Jan-Dec;22:17448069251413879
Modulation of the NF-κB signaling pathway by the combined strategy of tocilizumab and dexamethasone for asthma therapy.
Li X, Zhang J, Feng Y, Zhou Q, Zhang C
Respiratory research 2026 Jan 8;27(1):44
Respiratory research 2026 Jan 8;27(1):44
Poria cocos Attenuates LPS/D-Galactosamine-Induced Acute Liver Failure in Rats: An Integrative Exploratory Study Combining Network Pharmacology and In Vivo Validation.
Wen P, Jian X, Ren X, Zhao S, Yang Y, Ge H, Li L, Wang H, Li M, Wang L
International journal of molecular sciences 2026 Jan 30;27(3)
International journal of molecular sciences 2026 Jan 30;27(3)
Propyl Gallate Mitigates Gastric Injury Caused by Indomethacin in Wistar Rats.
Widodo F, Wang YY, Yen TB, Tseng KC, Chen YH, Lin SC, Tsai PS, Chen YK
Journal of agricultural and food chemistry 2026 Jan 14;74(1):941-951
Journal of agricultural and food chemistry 2026 Jan 14;74(1):941-951
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Guo CH, Wang QQ, Li JQ, Ji W, Chen L, Chang ML, Ma LY, Liu XL, Ni M
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Ezetimibe attenuates diabetic retinopathy via NRF2-mediated suppression of inflammation and oxidative stress.
Cheng L, Cheng S, Zhu R, Xu G
Journal of diabetes and its complications 2026 Feb;40(2):109250
Journal of diabetes and its complications 2026 Feb;40(2):109250
BvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB.
Wang Z, Yu X, Liu B, Ren D
MicrobiologyOpen 2026 Feb;15(1):e70219
MicrobiologyOpen 2026 Feb;15(1):e70219
Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms.
Chen YJ, Chen JW, Xie MR, Wang RZ, Wan YL, Zeng J, Zhong BW, Zhou SQ, Liu F
Immunity, inflammation and disease 2026 Feb;14(2):e70310
Immunity, inflammation and disease 2026 Feb;14(2):e70310
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Ren Z, Wu Z, Wu A, Zhang H, Lu J, Zhang J, Weng J, Zhang J, Chen S, Tan H, Guo T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Construction of a Novel Mucin/Tannic Acid Hydrogel for Diabetic Wound Repair.
Yue Y, Chen G, Cui X, Liao Y, Liu Z, Yang D
Journal of biomedical materials research. Part A 2026 Feb;114(2):e70044
Journal of biomedical materials research. Part A 2026 Feb;114(2):e70044
Engineered CCR2 Cell Membrane-Wrapped Cepharanthine Liposomes for Potential Targeted Attenuation of Acute Lung Injury.
Qing Y, Zhao W, Xue L, Luo Y, Gao Y, Sun X, Li F, Dai L, Mo J, Xu G, Bi Z, Yang S, Hee WT, Li J, Leng L
Cells 2026 Feb 4;15(3)
Cells 2026 Feb 4;15(3)
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Yi D, Wu Z, Li X, Shao B, Xiao Y, Li T, Zhang X, Zhu J, Yang T, Deng Y, Huang T, Qiu T, Bai J, Shi X, Wu C, Wu Z, Sun X, Wang N
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Ophiopogon japonicus-derived plant exosomes: a promising strategy for blocking the progression of diabetic vasculopathy to myocardial infarction.
Pan Y, Tan M, Li X, Chen Q, Tao J, Lin X, Zeng Z, Song Y, Jiang F
BMC complementary medicine and therapies 2026 Feb 21;26(1)
BMC complementary medicine and therapies 2026 Feb 21;26(1)
Exosomes derived from bone marrow mesenchymal stem cells facilitate repair of radiation-Induced skin injury by attenuating inflammation and apoptosis.
Wen Y, Song Y, Pan S, Zhang N, Tong X
Scientific reports 2026 Feb 2;16(1):6918
Scientific reports 2026 Feb 2;16(1):6918
Cigarette Smoke Extract Combined with LPS Upregulates PITPβ Expression in Chronic Pulmonary Inflammation and May Be Related to the EGFR/ERK Signaling Pathway.
Sun Y, Li H, Zhu X, Song J
Toxics 2026 Feb 18;14(2)
Toxics 2026 Feb 18;14(2)
Therapeutic targets established in adult ulcerative colitis exhibit correlations with disease severity and pathological relevance in pediatric pouchitis.
Otake S, Khorolgarav E, Yokobori T, Gombodorj N, Ogushi K, Suzuki N, Okami H, Zadeh SMM, Shiraishi T, Ozawa N, Dorjkhorloo G, Okada T, Sano A, Sakai M, Suzuki M, Kuwano H, Shirabe K, Saeki H
Scientific reports 2026 Feb 17;16(1)
Scientific reports 2026 Feb 17;16(1)
Mucoadhesive and corneal permeable nano eye drops for improved anti-glaucoma therapy.
Zhang X, Shao Q, Yu M, Huang Y, Wang Y, Wen Y, Nan K, Chen Y
Journal of nanobiotechnology 2026 Feb 15;24(1)
Journal of nanobiotechnology 2026 Feb 15;24(1)
7,7"-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma.
Wu YS, Lin HH, Wu KS, Huang YT, Liao JY, Chu SS, Wong TT, Hsieh CL, Chang CC, Sung SY, Lin CY, Lin YL
Journal of translational medicine 2026 Feb 12;24(1)
Journal of translational medicine 2026 Feb 12;24(1)
A tri-component hydrogel composed of Bletilla striata polysaccharide, carboxymethyl chitosan and cinnamaldehyde: Potent enhancement of diabetic wound healing.
Liu L, Yan A, Zeng J, Geng S, Li X, Huang G
Carbohydrate polymers 2026 Feb 1;373:124536
Carbohydrate polymers 2026 Feb 1;373:124536
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Zhang J, Ding M, Luo L, Huang D, Li S, Chen S, Fan Y, Liu L, Xie H, Liu G, Yu K, Wu J, Xiao X, Wu Y
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Kaempferol Mitigates Liver Injury Induced by Copper Toxicity Through the Activation of the Sirt1/Nrf2/FOXO3 Signaling Pathway.
Xu J, Wan W, Mu H, Gong S, Liu Y, Deng T
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70813
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70813
Customized ultra-flexible and adhesive spinal cord stimulation electrode for chronic pain management.
Tang M, Li Z, Sun L, He Q, Yang H, Wang JJ, Shu Y, Deng J
Materials today. Bio 2026 Apr;37:103018
Materials today. Bio 2026 Apr;37:103018
White light-triggered cascade NO/ROS-releasing platform with synergistic antibacterial and angiogenic effects for infected wound healing.
Tao S, Yang M, Fu S, Zhang Z, Mu J, Li T, Jiang X, Chen Y, Wang C, Niu H, Cao P, Liu Y
Acta biomaterialia 2026 Apr;214:465-482
Acta biomaterialia 2026 Apr;214:465-482
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
He X, Wang C, Zhang R, Wang Y, Zhang Y, Yang T, Zhang J, Rao S, Tang H, Peng X, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Hypoxia-activated dual donors of H(2)S and NO alleviate myocardial injury in coronary heart disease via synergistic mechanisms.
Zhou W, Ma C, Wang Y, Yang W, Gou S
European journal of medicinal chemistry 2026 Apr 5;307:118671
European journal of medicinal chemistry 2026 Apr 5;307:118671
Lp-PLA2-derived LysoPC drives dendritic cell immunogenic activation and Th17 inflammation in severe asthma.
Wang F, Min Z, Qian Y, Gao J, Yang Z, Jiang Z, Chen Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 28;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 28;75(1)
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
Liu Z, Zhang T, Wang S, Yin H, Shao X, Gao L, Lu X
Neurotoxicology 2026 Apr 21;114:103460
Neurotoxicology 2026 Apr 21;114:103460
α-hederin Targets USP5 to Inhibit Colorectal Tumorigenesis by Disrupting STAT3 Deubiquitination.
Feng H, Wang Q, Li L, Tao L, Zeng S, Li Z, Fan M, Yu C, Sun D, Shen W, Cheng H
International journal of biological sciences 2025;21(15):6697-6722
International journal of biological sciences 2025;21(15):6697-6722
miR-200a-3p in Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuates UVB-Induced Skin Inflammatory Response and Oxidative Stress via Keap1-Nrf2 Pathway.
Gui Q, Ding N, Liu J, Zhao Y, Du A, Zhu J, Wu H, Wu M, Wang Y, Zhu L
Stem cells international 2025;2025:7831890
Stem cells international 2025;2025:7831890
Temporal Effects of Disease Signature Genes and Core Mechanisms in the Hyperacute Phase of Acute Ischemic Stroke: A Bioinformatics Analysis and Experimental Validation.
Ding PL, Zhang KX, Yao F, Cui WQ, Liu ZL, Wang YR, Wang XY, Liu W, Zhao HY, Wu HY, Wang YH, Xu XQ
Mediators of inflammation 2025;2025:6808184
Mediators of inflammation 2025;2025:6808184
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
Zhou F, Tian Y, Liao W, Ma Q, Bao H, Meng F, Jiang J
Anesthesiology research and practice 2025;2025:6624776
Anesthesiology research and practice 2025;2025:6624776
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Zhi Y, Shu M, Tang P, Li Y, Guo M, Deng J, Mo H, Wu M, Liu B, Mai Y, Ling J, Zhao X, Zhang X, Zuo W
Stem cells international 2025;2025:6324980
Stem cells international 2025;2025:6324980
Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling.
Mizuno S, Kurobe-Takashima Y, Kuriki D, Susaki K, Otsuka K, Tsuchihashi T, Abe K, Kobayashi S
PloS one 2025;20(7):e0328206
PloS one 2025;20(7):e0328206
Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated Pyroptosis.
Tan Y, Ye Y, Huang C, Li J, Huang L, Wei X, Liang T, Qin E, Xiong G, Bin Y
Journal of inflammation research 2025;18:2447-2464
Journal of inflammation research 2025;18:2447-2464
Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis.
Kong L, Chen H, Zhang H, Zhang X, Chen J, Nie Y, Su Z, Lin L
Journal of inflammation research 2025;18:17129-17142
Journal of inflammation research 2025;18:17129-17142
Neuroprotective potential of isofraxidin: Alleviating parkinsonian symptoms, inflammation and microglial activation.
Wang TA, Li SY, Fann LY, Li IH, Liu TT, Hung HY, Chang CW, Cheng CC, Huang YC, Yu PY, Shih JH
Journal of central nervous system disease 2025;17:11795735241312661
Journal of central nervous system disease 2025;17:11795735241312661
Investigating the mechanisms of Sini San in alleviating inflammatory responses via multi-omics and the BDNF/TrkB/PI3K/AKT signaling pathway in depressive model rats.
Zeng JW, Han ZJ, He XT, Liu XJ, Wang HY, Yang SS, Bai J, Duan YJ, Lin L
Frontiers in psychiatry 2025;16:1628634
Frontiers in psychiatry 2025;16:1628634
Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice.
Yang Z, Zhang FR, Ren L, Bai JM, Wang SC, Li XY, Yang HJ, Xiao HH
Frontiers in pharmacology 2025;16:1596728
Frontiers in pharmacology 2025;16:1596728
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway.
Geng S, Wen J, Shen C, Liu L, Jiang Y, Fu J, Guan Y, Ye Z, Wu Y, Li C, Huang G
Frontiers in pharmacology 2025;16:1567193
Frontiers in pharmacology 2025;16:1567193
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Wang H, Chen B, Xiao P, Han D, Gao B, Yan Y, Zhao R, Pan T, Zhang J, Zhou M, Lv L, Gao H
Frontiers in microbiology 2025;16:1542801
Frontiers in microbiology 2025;16:1542801
Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.
Li D, Li Y, Yang S, Zhang X, Cao Y, Zhao R, Zhao Y, Jin X, Lu J, Wang X, Wang Q, Liu L, Wu M
Frontiers in pharmacology 2025;16:1515485
Frontiers in pharmacology 2025;16:1515485
Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice.
Wang X, Wang Q, Cai Z, Ni C, Wang H, Liu H, Zhao Y, Wang J, Liu S, Wang X
Frontiers in immunology 2025;16:1503807
Frontiers in immunology 2025;16:1503807
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.
Cheng Y, Zheng G, Huang H, Ni J, Zhao Y, Sun Y, Chang Y, Liu S, He F, Li D, Guo Y, Miao Y, Xu M, Wang D, Zhang Y, Hua Y, Yang S, Fan G, Ma C
Theranostics 2025;15(10):4345-4367
Theranostics 2025;15(10):4345-4367
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
Liu C, Gong J, Zhang L, Wang Y, Huang Y, Ju R
Frontiers in cellular and infection microbiology 2025;15:1664897
Frontiers in cellular and infection microbiology 2025;15:1664897
Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.
Wang H, Ma R, Qi R, Liu Z, Li Y, Wu X, Zhao C, Ma Q, Zhan K
Frontiers in nutrition 2025;12:1704168
Frontiers in nutrition 2025;12:1704168
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Shen J, Bin Z, Shen Y, Xie F, Zhang X, Tan X, Xu H
Frontiers in medicine 2025;12:1676071
Frontiers in medicine 2025;12:1676071
Senescent Microglia Mediate Neuroinflammation-Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1.
Liu K, Fan D, Wu HP, Hu XY, He QL, Wu XM, Shi CN, Yang JJ, Ji MH
Aging cell 2025 Sep;24(9):e70167
Aging cell 2025 Sep;24(9):e70167
Investigating the abnormalities and potential therapeutic targets in umbilical cord mesenchymal stem cells from preeclampsia.
He F, Cai W, Cai S, Ou C, Lu S, Huang Z, Li S, Pan S
Placenta 2025 Sep;169:49-59
Placenta 2025 Sep;169:49-59
Flavonoids in Rosa roxburghii Tratt Fermentation Broth Ameliorate Obesity via DNMT3a/SIRT1-Mediated Epigenetic Modulation.
Liu M, Li H, Zhang J, Zhong Y, Huang C, Zhu L, Hu Z, Xu Y, Zhao S, Pan W
Food science & nutrition 2025 Sep;13(9):e70892
Food science & nutrition 2025 Sep;13(9):e70892
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
Lu J, Wang H, Zhang H, Li J, Li H, Chen Q, Han D, Liu J, Lv L, Xiong J, Yuan K, Wei X, Sheng S, Liu F, Shi Y, Dong Z, Li Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
Sang W, Zhang X, Hu Q, Jiang B, Guan J, Huang Z, Sun L, Sun D
Gene 2025 Sep 5;963:149572
Gene 2025 Sep 5;963:149572
Investigating the Mechanism of Yiqi Huoxue Jieyu Granules Against Ischemic Stroke Through Network Pharmacology, Molecular Docking and Experimental Verification.
Chen Y, Zhou H, Zhang T, Wan H
Pharmaceuticals (Basel, Switzerland) 2025 Sep 5;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 5;18(9)
Chronic kidney disease facilitates TNF-α + neutrophils dysfunction and progression in oral squamous cell carcinoma.
Peihui Z, Jianing C, Chuwen L, Hanjin R, Wenyu Y, Jiaqi Z, Yujie L, Li W
International immunopharmacology 2025 Sep 23;162:115184
International immunopharmacology 2025 Sep 23;162:115184
Targeting Bcl3/NF-κB p50 Pathway for Neuroinflammation Attenuation and RGCs Protection in Retinal Ischemia/Reperfusion Injury.
Chen M, Zhang X, Zeng Z, Fan C, Chen S, Quan C, Chen J, You M, Xia X
Investigative ophthalmology & visual science 2025 Sep 2;66(12):63
Investigative ophthalmology & visual science 2025 Sep 2;66(12):63
Single-Cell Transcriptomics of Human Pericarotid Lymph Nodes Indicating Stability of Carotid Atherosclerotic Plaques.
Sun T, Wu Y, Liu G, Xue Z, Yu M, Mao B, Han M, Liang X, Ling L, You N, Ji L, Liu H, Xu C, Qin Z, Zhao P, Wang D
Journal of the American Heart Association 2025 Sep 16;14(18):e039777
Journal of the American Heart Association 2025 Sep 16;14(18):e039777
Diosmetin Alleviates Cerebral Ischemia/Reperfusion Injury by Modulating Tryptophan Metabolism through the Microbiota-Gut-Brain Axis.
Peng M, Fu J, Song Y, Lu M, Zhang B
Journal of agricultural and food chemistry 2025 Sep 10;73(36):22448-22465
Journal of agricultural and food chemistry 2025 Sep 10;73(36):22448-22465
Curcumin-loaded nanoscale coordination polymers for ROS scavenging and anti-inflammatory therapy in atherosclerosis.
Ding S, Xu W, Liu X, Wu Z, He X, Huang Y, Chen J, Yao W, Zhou H, Yang Y, Pu J
Materials today. Bio 2025 Oct;34:102152
Materials today. Bio 2025 Oct;34:102152
Rutin alleviates preoperative anxiety stress-induced persistent postoperative pain by inhibiting microglia-mediated abnormal synaptic engulfment in the spinal cord dorsal horn.
Zhang Y, Yang H, Zhao Y, Ni K, Sun J, Ma Z
International immunopharmacology 2025 Oct 30;164:115309
International immunopharmacology 2025 Oct 30;164:115309
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
LCCPs causes cartilage damage and exacerbates osteoarthritis by inducing necroptosis of chondrocytes.
Zhang R, Ma S, Kong Y, Deng H, Wang G, Xu C, Tian X, Lan H
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126767
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126767
Human amniotic mesenchymal stem cell-derived exosome inhibits ferroptosis through the suppression of JNK/MAPK-mediated EGR1 expression in spontaneous intracerebral hemorrhage.
Wang Y, Zhou L, Xu K
Brain research bulletin 2025 Oct 15;231:111553
Brain research bulletin 2025 Oct 15;231:111553
Porphyromonas gingivalis-Lipopolysaccharide Induced Gingival Fibroblasts Trained Immunity Sustains Inflammation in Periodontitis.
Liu J, Tian H, Ju J, Nie F, Yin Q, Zhao J, Wang S, Guo H, Yang P
Journal of periodontal research 2025 Nov;60(11):1156-1167
Journal of periodontal research 2025 Nov;60(11):1156-1167
Significance of integrated clinical and proteomic characteristics analysis for pathogenesis and management of Crohn's disease with concomitant psoriasis.
Zhang H, He C, Fan X, Song Q, Lin C, Zhou P, Song Y, Li N, Shi Y, Lin Z, Chen Q, Zheng Y, Wang S, Li Z, Zhang W, Liu Q, Qing Q, Sun Y, Huang B, Li M
EBioMedicine 2025 Nov;121:105981
EBioMedicine 2025 Nov;121:105981
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Zhang J, Huang X, Tang Y, Zhong X, Wang J, Wei M, Han X, Ke Y, Ba X
Communications biology 2025 Nov 30;9(1):3
Communications biology 2025 Nov 30;9(1):3
Elimination of a neutrophil Pad4 byproduct restores stem cell-mediated bone regeneration in hyperglycemia.
Zhang L, Li J, Wei X, Yang W, He W, Liu W
Nature communications 2025 Nov 28;16(1):11720
Nature communications 2025 Nov 28;16(1):11720
Multifunctional Inorganic-Nanosheets-Based Nanohydrogel for Periodontal Bone Regeneration via Antibacterial and Anti-Ferroptotic Immunomodulation.
Yuan X, Wen S, Shi H, Luo Y, Wang S, He Z, Song X, Long H
ACS applied materials & interfaces 2025 Nov 26;17(47):64149-64167
ACS applied materials & interfaces 2025 Nov 26;17(47):64149-64167
QuYuShengXin formula reshapes bile-acid-mediated macrophage polarization in the treatment of ulcerative colitis.
Ni J, Lu Y, Tan J, Jiang J, Wang Y, Gan D, Cui C, Wu J, Yang H, Wang Z
BMC complementary medicine and therapies 2025 Nov 22;26(1):1
BMC complementary medicine and therapies 2025 Nov 22;26(1):1
Cellular senescence of RANKL(+) osteoblasts and Th17 cells in severe periodontitis with occlusal trauma.
Wang Y, Nakagawa M, Luo C, Kanda R, Matsushima Y, Nishiura A, Honda Y
Journal of prosthodontic research 2025 Nov 18;69(4):533-542
Journal of prosthodontic research 2025 Nov 18;69(4):533-542
Cu/Zn/histidine supramolecular assemblies with optimized Cu catalytic sites as an alternative of superoxide dismutase.
Jin H, Zhu X, Zhang M, Zheng H, Chen Y, Yao D, Liu S, Zhang H
Nature communications 2025 Nov 18;16(1):10075
Nature communications 2025 Nov 18;16(1):10075
Chrysin Improves Cognitive Dysfunction in Rats with Intracerebral Hemorrhage by Regulating the Nrf2/GPX4 Pathway to Inhibit Ferroptosis.
Guo D, Shao Z, Liu D, Guan Y, Lian D, Feng J, Zhang C, Peng H
Molecular neurobiology 2025 Nov 13;63(1):35
Molecular neurobiology 2025 Nov 13;63(1):35
Mechanism of the traditional Chinese medicine SMBJ alleviates diabetes mellitus-induced Leydig cell dysfunction in rats testes.
Zhang W, Liu Y, Tong L, Jin Y, Gao C, Cui Y, Jin B, Sun D
Scientific reports 2025 Nov 12;15(1):39656
Scientific reports 2025 Nov 12;15(1):39656
Role of intestinal SCFAs homeostasis in the hepatoprotective effect of Clostridium butyricum in T2DM.
Yan M, Pan D, Chen L, Pang J, Shao Y, Cheng Q, Liu Y, Yin Z, Jiang Z, Sha P, Huang Y, Fan Y, Qian S, Wang T, Lu Q, Yang T
NPJ biofilms and microbiomes 2025 Nov 11;11(1):206
NPJ biofilms and microbiomes 2025 Nov 11;11(1):206
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
Yang J, Yang J, Hu H, Jiang W, Zhang X, Wang G, Zhao F, Liao Y, Jin Y
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
PDGFR-α Mediated the Neuroinflammation and Autophagy via the JAK2/STAT3 Signaling Pathway Contributing to Depression-Like Behaviors in Myofascial Pain Syndrome Rats.
Liu Y, Jin F, Chen Q, Liu M, Li X, Zhou L, Li X, Yang S, Qi F
Molecular neurobiology 2025 May;62(5):5650-5663
Molecular neurobiology 2025 May;62(5):5650-5663
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
Zheng Y, Wang S, Jin W, Li Z, Yang G, Li X, Li N, Wang Y, Sheng F, Song Z
Bioactive materials 2025 May;47:295-312
Bioactive materials 2025 May;47:295-312
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
Mu Y, Li W, Wei D, Zhang X, Yao L, Xu X, Wang X, Zhang Z, Chen T
Life sciences in space research 2025 May;45:158-169
Life sciences in space research 2025 May;45:158-169
Integrating Serum Pharmacochemistry With Network Pharmacology to Elucidate the Mechanism of Wushen Decoction in the Prevention and Treatment of Lower Extremity Erysipelas.
Wang Y, Dai X, Zhu X, Wang W, Wang C, Li S, Sun S, Gao X, Qin K
Biomedical chromatography : BMC 2025 May;39(5):e70076
Biomedical chromatography : BMC 2025 May;39(5):e70076
Auricular Transcutaneous Vagus Nerve Stimulation Enhances Post-Stroke Neurological and Cognitive Recovery in Mice by Suppressing Ferroptosis Through α7 Nicotinic Acetylcholine Receptor Activation.
Gong H, Zheng F, Niu B, Wang B, Xu L, Yang Y, Wang J, Tang X, Bi Y
CNS neuroscience & therapeutics 2025 May;31(5):e70439
CNS neuroscience & therapeutics 2025 May;31(5):e70439
Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing.
Zhang X, Li R, Li S, Cui W, Wang D, Zhu Y, Liu Z, Hou Y, Lee S
International journal of biological macromolecules 2025 May;308(Pt 3):142280
International journal of biological macromolecules 2025 May;308(Pt 3):142280
A dual gene-activated dermal scaffolds loaded with nanocomposite particles expressing of VEGF and aFGF: Promoting wound healing by early vascularization.
Wang J, Liu H, Liu M, Shen T, Weng T, He F, Wang X
International journal of biological macromolecules 2025 May;307(Pt 1):141831
International journal of biological macromolecules 2025 May;307(Pt 1):141831
Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway.
Yang S, Gao XQ, Tan AH, Ge P
Chemistry & biodiversity 2025 May;22(5):e202402208
Chemistry & biodiversity 2025 May;22(5):e202402208
Resveratrol Promotes Wound Healing by Enhancing Angiogenesis via Inhibition of Ferroptosis.
Pan Y, Xia M, Luo J, Lu S
Food science & nutrition 2025 May;13(5):e70254
Food science & nutrition 2025 May;13(5):e70254
Targeting inflammation and necroptosis in diabetic kidney disease: A novel approach via PPARα modulation.
Wang Y, Feng X, Li Y, Niu S, Li J, Shi H, Wang G, Wang L
International immunopharmacology 2025 May 8;154:114562
International immunopharmacology 2025 May 8;154:114562
MiR-29a-3p ameliorate behavioral deficiency in hypoxia-ischemia brain damage in neonatal mice by inhibiting BTG2.
Luo Q, Xing X, Song Y, Gu B, Hu Q, Liu W, Xiao Y, Wang Z
Behavioural brain research 2025 May 28;486:115552
Behavioural brain research 2025 May 28;486:115552
COP1 Overexpression Attenuates Nociceptive Behaviors and Neuroinflammation in Cancer-Induced Bone Pain by Suppressing c/EBPβ.
Li DY, Liu L, Gao SJ, Liu DQ, Zhang LQ, Wu JY, Song FH, Dai XY, Zhou YQ, Mei W
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 16;20(1):54
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 May 16;20(1):54
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Zhao DP, Xue A, Yuan K, Zuo K, Li Y, Bian ZH, Xu HD, Cheng SM, Yang M, Zhao HM, Ma X, Lei X, Zhang N
Journal of ethnopharmacology 2025 May 12;347:119792
Journal of ethnopharmacology 2025 May 12;347:119792
Bio-Mimicking Nanoparticle System Facilitates Sonodynamic-Mediated Clearance of Extensively Drug-Resistant Bacteria.
Gao F, Zhou R, He Y, Zhang Y, Bao C, Feng G
ACS biomaterials science & engineering 2025 May 12;11(5):2988-3002
ACS biomaterials science & engineering 2025 May 12;11(5):2988-3002
Cadmium exposure induces Leydig cell injury via necroptosis caused by oxidative stress and TNF-α/TNFR1 signaling.
Zheng X, Sun Y, Wang J, Yin Y, Li Z, Liu B, Hu H, Xu J, Dai Y, Kanwar YS, Tang Y
Biochemical and biophysical research communications 2025 May 1;761:151717
Biochemical and biophysical research communications 2025 May 1;761:151717
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
Liu S, Yang Y, Li Q, Yu L, Zong Z, Zang R, Ji W, Sun S
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
Extracellular HSP70 facilitated β-glucan induced trained immunity in macrophages to suppress sepsis via TLR2-NF-κB axis.
Qi R, Cheng X, Chen S, Fan J
Cytokine 2025 Mar;187:156861
Cytokine 2025 Mar;187:156861
MOF-818 Nanozyme Suppresses Calcium Oxalate Kidney Stones by Alleviating Oxidative Stress and Inflammatory Injury.
Tian Y, Ye Z, Wang X, Guan H, Liu W, Duan X, Liu Y, Zeng G, Liu H
Advanced healthcare materials 2025 Mar;14(8):e2401574
Advanced healthcare materials 2025 Mar;14(8):e2401574
Trojan Horse-Like Biohybrid Nanozyme for Ameliorating Liver Ischemia-Reperfusion Injury.
Zheng DF, Zha XJ, Jiang EL, Qiu Y, Yang W, Xiao WD
Advanced healthcare materials 2025 Mar;14(7):e2404458
Advanced healthcare materials 2025 Mar;14(7):e2404458
Targeting the NF-κB p65-MMP28 axis: Wogonoside as a novel therapeutic agent for attenuating podocyte injury in diabetic nephropathy.
Li X, Zhao S, Xie J, Li M, Tong S, Ma J, Yang R, Zhao Q, Zhang J, Xu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156406
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156406
Baicalin, Amoxicillin, and Probenecid Provide Protection in Mice Against Glaesserella parasuis Challenge.
Li J, Luo R, Fu Y, Liu S, Dong Q, Sun Y, Tian X, Zhu Y, Wang P, Guo L, Lu Q, Ye C, Fu S, Qiu Y
Biomolecules 2025 Mar 31;15(4)
Biomolecules 2025 Mar 31;15(4)
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
Pekmez M, Mete ŞB, Aksüt Y, Öğütcü İ, Baştürk FN, Gerçek YC, Şengelen A
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
DKS26 Alleviates Ischemia-Reperfusion Injury-Induced Acute Kidney Injury by Stabilizing Vitamin D Receptors to Inhibit the Inflammatory Pathway of NF-κB P65.
Liang L, Ruan Y, Yu X, Tan W, Xu X, Jia J, Peng J, Wang F, Peng Y, Chen Y, Liu L, Guo B, Zhang J, Wang Y
International journal of molecular sciences 2025 Mar 25;26(7)
International journal of molecular sciences 2025 Mar 25;26(7)
Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the Brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD Mice.
Bhuiyan P, Zhang W, Liang G, Jiang B, Vera R, Chae R, Kim K, Louis LS, Wang Y, Liu J, Chuang DM, Wei H
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Mar 17;20(1):26
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Mar 17;20(1):26
Chronic exposure to liquid crystal monomer EBCN at environmentally relevant concentrations induces testicular dysfunction via the gut-testis axis.
Wu J, Lv D, Lin W, Mao Y, Xia Y, Feng L, Zhao T, Mao X, Shu F, Guo H
Journal of hazardous materials 2025 Mar 15;486:137033
Journal of hazardous materials 2025 Mar 15;486:137033
Brown adipose tissue transplantation ameliorates hindlimb ischemic damage in diabetic mice.
Lu T, Liu A, Li C, Li Y, Yang B, Liu Q, Jiang H
Scientific reports 2025 Mar 14;15(1):8820
Scientific reports 2025 Mar 14;15(1):8820
Diallyl Trisulfide Attenuates Ischemia-Reperfusion-Induced ER Stress and Kidney Dysfunction in Aged Female Mice.
Pushpakumar S, Juin SK, Almarshood H, Gondim DD, Ouseph R, Sen U
Cells 2025 Mar 12;14(6)
Cells 2025 Mar 12;14(6)
Identification of biomarkers associated with pathological tumor staging and their utility in the diagnosis and prognosis of prostate cancer.
Xu S, Shi H, Liu Y, Lin J, Wu X, Lu R, Fan Y, Tan W
Laboratory medicine 2025 Mar 10;56(2):118-128
Laboratory medicine 2025 Mar 10;56(2):118-128
Electroacupuncture Neural Stimulation Mitigates Bladder Dysfunction and Mechanical Allodynia in Cyclophosphamide Induced Cystitis through Downregulation of the BDNF-TrkB Signaling Pathway.
Su Y, Yang F, Xie JC, Zhang C, Luo RX, Li WS, Liu BL, Su MZ
eNeuro 2025 Mar 10;12(3)
eNeuro 2025 Mar 10;12(3)
P2Y6R Inhibition Induces Microglial M2 Polarization by Promoting PINK1/Parkin-Dependent Mitophagy After Spinal Cord Injury.
Lin J, Sun Y, Huang H, Yu C, Kuang W, Wang Y, Zhu L
Molecular neurobiology 2025 Jun;62(6):7054-7074
Molecular neurobiology 2025 Jun;62(6):7054-7074
Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation.
Zhou J, Ou M, Yuan B, Yan B, Wang X, Qiao S, Huang Y, Feng L, Huang L, Luo Y
Photoacoustics 2025 Jun;43:100721
Photoacoustics 2025 Jun;43:100721
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis.
Huang Y, Li G, Li D, Liu C, Chen M, Cai L, Sun M, Xu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156700
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156700
Integrated network pharmacology and experimental validation to elucidate the mechanism of celastrol in mitigating sepsis-induced acute lung injury in mice.
Zhu D, Zhang J, Huang X, Wei N, Jiang J, Li J, Liu L, Liu Y, Zhou J, Jia J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156678
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156678
Effect of COL11A1 on oral squamous cell carcinoma.
Liu YH, Li D, Zhang HL, Zhang BH, Song WJ, Li TK
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Sun X, Xu X, Zhao X, Ma J, Wang T, Yue X, Sun X, Li X, Sun X, Zhang W, Zhang K, Zhang D, Zhao X, Jin W, Wang J
ACS nano 2025 Jun 24;19(24):22141-22162
ACS nano 2025 Jun 24;19(24):22141-22162
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
Liu Y, Liu Y, Ye Z, Wang X, Li J, Mei PL, Duan L, Wang B, Xu C, Xiong W, He Y, Ye Q
Stem cell research & therapy 2025 Jun 2;16(1):272
Stem cell research & therapy 2025 Jun 2;16(1):272
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Cheng Z, Gao H, Shi P, Zhang A, Chen X, Chen Y, Gan W, Zhao K, Li S, Yang C, Zhang Y
Bone research 2025 Jun 12;13(1):62
Bone research 2025 Jun 12;13(1):62
Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.
Ye L, Zheng X, Yang Y, Lyu Y
Biomedical reports 2025 Jul;23(1):111
Biomedical reports 2025 Jul;23(1):111
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
Zhang XL, Jiang LL, Duan HT, Hu HY
Scientific reports 2025 Jul 27;15(1):27351
Scientific reports 2025 Jul 27;15(1):27351
C18:0 GM3 ganglioside's efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation.
Liu TT, Liu CT, Li IH, Chu YC, Hung HY, Chiu CH, Chou TK, Li SY, Wang TA, Shih JH
Behavioral and brain functions : BBF 2025 Jul 26;21(1):25
Behavioral and brain functions : BBF 2025 Jul 26;21(1):25
Gallic Acid and Taurine Attenuate Thiamethoxam-Induced Hepatotoxicity in Rats by Modulating SIRT-1/PGC-1α, NF-κB/iNOS, and p53/Bax/Caspase-3 Pathways.
Elazab ST, Safhi FA, Al-Akeel RK, Deraz RH, Sarkar S, Gamal Eldin REA
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
Stem cell secretome armed magneto-actuated micromotors as spatio-temporal manipulators for wound healing acceleration.
Jiang J, Liang H, Ye Y, Huang W, Miao J, Tan H, Hu Z, Tian H, Qin H, Zhang X, Zhang L, Gao J, Shen X, Wang S, Peng F, Tu Y
Nature communications 2025 Jul 22;16(1):6754
Nature communications 2025 Jul 22;16(1):6754
High-Fructose High-Fat Diet Renders the Retina More Susceptible to Blue Light Photodamage in Mice.
Kao MW, Yeh WJ, Yang HY, Wu CH
Antioxidants (Basel, Switzerland) 2025 Jul 22;14(8)
Antioxidants (Basel, Switzerland) 2025 Jul 22;14(8)
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Huang J, Teng Y, Yan P, Yang Y, Lin S, Wu Q, Du Q, Li X, Yao M, Li J, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2025 Jul 16;17(14)
Cancers 2025 Jul 16;17(14)
Normal stress on surface of mesenchymal stem cells boosts extracellular vesicle secretion and regenerative bioactivity.
Bai C, Ren H, Zhang F, Li D, Feng Q, Li Y, Chen T, Li C, Xiao X, Zhang H, Hu L
Journal of nanobiotechnology 2025 Jul 1;23(1):476
Journal of nanobiotechnology 2025 Jul 1;23(1):476
A Novel Effect of Id2 in Microglia TNFα Regulation.
Wang W, Asiru, Luo G, Chen Y, Cui Y, Ping S, Chen Y
Molecular neurobiology 2025 Jan;62(1):304-321
Molecular neurobiology 2025 Jan;62(1):304-321
High glucose enhances malignant progression of MDA-MB-231 cells through cumulative effect.
Zhang G, Liu Z, Zheng H, Xu Y, Zhang D, Chen Q, Luo D
Toxicology letters 2025 Jan;403:17-31
Toxicology letters 2025 Jan;403:17-31
Supramolecular nanoparticle loaded with bilirubin enhances cartilage protection and alleviates osteoarthritis via modulating oxidative stress and inflammatory responses.
Zhao X, Huang H, Jiang X, Zheng S, Qiu C, Cheng Y, Lin Y, Wang Y, Yan Y, Di X, Hu M, Zhu W, Wu F, Shi X, Chen R, Kou L
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114243
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114243
Short-term exposure to low doses of aflatoxin B1 aggravates nonalcoholic steatohepatitis by TLR4-mediated necroptosis.
Zeng J, Chen L, Tang J, Xue J, Wang Q, Feng X, Chen X, Huang K, Gan F
Free radical biology & medicine 2025 Jan;226:129-142
Free radical biology & medicine 2025 Jan;226:129-142
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure.
Wang Y, Wang Z, Hao H, Zhao Y, Wang J, Wang W
Toxics 2025 Jan 5;13(1)
Toxics 2025 Jan 5;13(1)
Tanshinone IIA, a component of Salvia miltiorrhiza Bunge, attenuated sepsis-induced liver injury via the SIRT1/Sestrin2/HO-1 signaling pathway.
Tian W, Song P, Zang J, Zhao J, Liu Y, Wang C, Fang H, Wang H, Zhao Y, Liu X, Gao Y, Cao L
Journal of ethnopharmacology 2025 Jan 31;340:119169
Journal of ethnopharmacology 2025 Jan 31;340:119169
Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges.
Zhang W, Liu H, Zhang D, Yi Y, Tao L, Zhu Y, Huang S, Zhao X, Shao Q, Li P, Weng Y, Lu W, Zhang J, Zhang H, Chen Y, Weng D
eLife 2025 Jan 31;13
eLife 2025 Jan 31;13
In situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment.
He W, Ding F, Zhang L, Liu W
Nature communications 2025 Jan 30;16(1):1162
Nature communications 2025 Jan 30;16(1):1162
IL-17A exacerbates synovial inflammation in osteoarthritis via activation of endoplasmic reticulum stress.
Sun W, Li X, Zhang L, Zhang Y, Shi Y, Tao H, Zhou J, Hao Y, Chen G, Gu C, Yang X
International immunopharmacology 2025 Jan 3;145:113733
International immunopharmacology 2025 Jan 3;145:113733
tRNA-derived fragment 3031B regulates human anterior cruciate ligament cell proliferation and survival by targeting RELA.
Long D, Deng Z, Li M, Li W, Zhong Y, Lin Z, He A, Kang Y, Mao G
Gene 2025 Jan 15;933:148897
Gene 2025 Jan 15;933:148897
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
Zhang L, Wang K, Huang L, Deng B, Chen C, Zhao K, Wang W
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
Li J, Wu D, Su Z, Guo J, Cui L, Su H, Chen Y, Yu B
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
Exploring the potential anti-COPD ingredients and mechanisms of the Qingfei decoction based on UHPLC-HRMS, network pharmacology and transcriptomic analysis.
Zhang T, Guo Z, Ma T, Li S, Dai Z, Luo Y, Gao F, Zeng Q, Lu J, Wang J, Liu Y, Xu B, Lei H
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Jan 15;1251:124420
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Jan 15;1251:124420
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Subconjunctival injection of microcrystalline prodrug of dexamethasone for long-acting anti-inflammation after phacoemulsification surgery.
Zhou X, Xu Z, Dong Y, Cai M, Chen Z, Mu J, Yuan B, Hua X, Yuan X, Guo S
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:399-412
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:399-412
Microglia phagocytosis of PNNs mediates PV-positive interneuron dysfunction and associated gamma oscillations in neuroinflammation-induced cognitive impairment in mice.
Liu K, Gao YZ, Wu XM, Hu XY, Shi CN, He QL, Wu HP, Yao H, Ma DQ, Yang JJ, Ji MH
Neuropharmacology 2025 Jan 1;262:110205
Neuropharmacology 2025 Jan 1;262:110205
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
Zhang J, Ge Q, Du T, Kuang Y, Fan Z, Jia X, Gu W, Chen Z, Wei Z, Shen B
Life science alliance 2025 Feb;8(2)
Life science alliance 2025 Feb;8(2)
Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
Zhu JX, Chu F, Zhao WM, Shi R, Wang ZJ, Li XL, Zhu YY, Wang DG
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1973-1989
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1973-1989
Long-chain chlorinated paraffins (LCCPs) exposure causes senescence and inflammatory damage in cardiomyocytes.
Zhang R, Zhang M, Wang G, Wu D, Kong Y, Deng H, Li J, Lan H, Wu M
Journal of environmental management 2025 Feb;375:124166
Journal of environmental management 2025 Feb;375:124166
Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling.
Ge S, Sun A, Zhou X, Niu P, Chen Y, Bao X, Yu M, Zhong Z, Sun J, Li G
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413371
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413371
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Chen J, Zhu T, Yang J, Shen M, Wang D, Gu B, Xu J, Zhang M, Hao X, Tang Z, Tong J, Du Y, Zhang B, Li H, Xu M
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
Wang Q, Gao Y, Chen Y, Wang X, Pei Q, Zhang T, Wang C, Pan J
Advanced healthcare materials 2025 Feb;14(4):e2404260
Advanced healthcare materials 2025 Feb;14(4):e2404260
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Yang ZC, Lin H, Liu GJ, Pan H, Zhu JL, Zhang XH, Gao F, Wang Z, Wang ZH
Stem cell research & therapy 2025 Feb 7;16(1):52
Stem cell research & therapy 2025 Feb 7;16(1):52
Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice.
Wang Q, Qin B, Yu H, Zeng J, Fan J, Wu Q, Zeng R, Yu H, Zhang X, Li M, Zhou Y, Diao L
Scientific reports 2025 Feb 7;15(1):4649
Scientific reports 2025 Feb 7;15(1):4649
Ferroptosis Induces gut microbiota and metabolic dysbiosis in Collagen-Induced arthritis mice via PAD4 enzyme.
Zhu X, Lu H, Li W, Niu S, Xue J, Sun H, Zhang J, Zhang Z
Gene 2025 Feb 5;936:149106
Gene 2025 Feb 5;936:149106
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Li J, Wu Z, Li N, Wang J, Huang M, Zhu L, Wan G, Zhang Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Blocking the p38 MAPK Signaling Pathway in the Rat Hippocampus Alleviates the Depressive-like Behavior Induced by Spinal Cord Injury.
Xie Z, Xu T, Chen J, Gui Y, Wan D, Li M
ACS chemical neuroscience 2025 Feb 19;16(4):595-603
ACS chemical neuroscience 2025 Feb 19;16(4):595-603
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Li W, Li Y, Xiao L, Xie Z, Peng J, Huang W, Li X, Meng Y
Journal of translational medicine 2025 Feb 14;23(1):181
Journal of translational medicine 2025 Feb 14;23(1):181
Eu-Doped TiO(2) Coatings via One-Step In Situ Preparation Enhance Macrophage Polarization and Osseointegration of Implants.
Zhang B, Qu H, Zhang Z, Wang X, Dou Z, Li X, Cao R, Zhang K, Zhang J, Zhang Q
ACS applied materials & interfaces 2025 Feb 12;17(6):8886-8900
ACS applied materials & interfaces 2025 Feb 12;17(6):8886-8900
Analysis of ferroptosis-related genes in cerebral ischemic stroke via immune infiltration and single-cell RNA-sequencing.
Fan W, Zheng J, Jiang F
BMC medical genomics 2025 Feb 11;18(1):31
BMC medical genomics 2025 Feb 11;18(1):31
Toll-like receptor 4 inhibition by pyridostigmine is associated with a reduction in hypertension and inflammation in rat models of preeclampsia.
Ali MA, Zeng M, Alkuhali AA, Zeng Z, Yuan M, Wang X, Liu X, Issotina Zibrila A, Liu J, Wang Z
Journal of hypertension 2025 Feb 1;43(2):336-350
Journal of hypertension 2025 Feb 1;43(2):336-350
Spinal AT1R contributes to neuroinflammation and neuropathic pain via NOX2-dependent redox signaling in microglia.
Zhang W, Jiao B, Yu S, Zhang K, Sun J, Liu B, Zhang X
Free radical biology & medicine 2025 Feb 1;227:143-156
Free radical biology & medicine 2025 Feb 1;227:143-156
Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice.
Zhu Y, Zhang Y, Zhang Q, Song P, Zhang J, Ma A, Wang C, Gao P, Yang T, Zhou L, Shi Q, Wong YK, Luo Y, Tang H, Wang J
Exploration (Beijing, China) 2025 Dec;5(6):20240069
Exploration (Beijing, China) 2025 Dec;5(6):20240069
Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway.
Xu Z, Zhang M, Zhang X, Han H, Ye W, Chen Z, Lv Z, Liu Y, Liu Z, Gong J, Zhu B, Zhou S, Zhu R, Tao C, Zhang G, Yan X
Renal failure 2025 Dec;47(1):2490202
Renal failure 2025 Dec;47(1):2490202
Functionalized hydrocaffeic acid-chitosan/EGTA hydrogel rescues mitochondrial dysfunction for immunomodulation and joint repair in rheumatoid arthritis.
Li J, Ni Y, Tao Y, Cai H, Wu A, Zhang F, Meng S, Luo Y, Zhang W, Wang Y
Materials today. Bio 2025 Dec;35:102605
Materials today. Bio 2025 Dec;35:102605
Herb-based multicomponent carrier-free hydrogel with antipyretic and anti-inflammatory dual effects by regulating MAPK and NF-κB signaling pathway.
Wang P, Huang X, Geng S, Huang G, Pi W, Han N, Zhang Y, Xiao E, Lin Z, Yuan K, Lei H, Xu A
Materials today. Bio 2025 Dec;35:102371
Materials today. Bio 2025 Dec;35:102371
Bovine tubulin cofactor D (TBCD) disrupts tubulin dimers and inhibits tumor growth via the TNF-α signaling pathways-mediated ROS production.
Wang H, Guo J, Yang J, Wu X, Wu F, Wu H, Zhan Y, Zhang H
International journal of biological macromolecules 2025 Dec;334(Pt 1):148987
International journal of biological macromolecules 2025 Dec;334(Pt 1):148987
Structural characterisation of a polysaccharide from Sanghuangporus vaninii and its synergistic anti-hepatocellular carcinoma activity in combination with sorafenib.
Li J, Shi M, Jia B, Liu S, Zhao Y
International journal of biological macromolecules 2025 Dec;334(Pt 1):148778
International journal of biological macromolecules 2025 Dec;334(Pt 1):148778
Tryptophan derivatives as non-invasive diagnostic indicators for obesity-related MASLD in children and adolescents.
Zhan S, Wang X, Wang C, Zhu B, Gao J, Peng Z, Wang R, Yang Y, Zhang L, Wang T, Wu J, Wu W, Huang K, Dong G, Ren Q, Wang S, Wang S, Zhou X, Xu L, Fu J, Guo X
Diabetes, obesity & metabolism 2025 Dec;27(12):7544-7560
Diabetes, obesity & metabolism 2025 Dec;27(12):7544-7560
Pyridostigmine attenuates placental-ischemia-upregulated placental angiotensin II type 1 receptor in rats.
Issotina Zibrila A, Alkuhali AA, Yuan M, Zeng Z, Ali MA, Zeng M, Elenany AM, Manzoor M, Wang X, Zhao M, Jin L, Liu J
Peptides 2025 Dec;194:171450
Peptides 2025 Dec;194:171450
Pyruvate kinase M2 (PKM2) regulates rheumatoid arthritis by mediating glycolysis reprogramming through the Akt/mTOR pathway.
Liao HY, Zhang GH, Zheng JX, Lu JY, Hao JY, Tan M, Wang ZD, Shen HL
The international journal of biochemistry & cell biology 2025 Dec;189:106870
The international journal of biochemistry & cell biology 2025 Dec;189:106870
E3 ubiquitin ligase Pellino1 suppresses acinar cell necroptosis and alleviates severe acute pancreatitis by promoting ubiquitin-dependent receptor-interacting protein kinase 3 (RIP3) degradation.
Chen J, Huang Z, Jing P, Shi H, Liu S, Feng L, Long Y, Ye M, Fu W, Tan P
British journal of pharmacology 2025 Dec;182(24):6100-6119
British journal of pharmacology 2025 Dec;182(24):6100-6119
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Zhang H, Huang X, Chen R, Lin W, Li L, Peng X, Yang X, Chen X, Guo T, Weng J, Li J, Yuan Q, Tan H, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Treadmill exercise ameliorates atherogenesis and vascular inflammation in ApoE(-/-) mice via circulating exosome-derived let-7c-5p.
Guo W, Wang J, Chang Z, Lin S, Sha G, Wang S, Huang J, Hu M, Xia J
Scientific reports 2025 Dec 9;16(1):585
Scientific reports 2025 Dec 9;16(1):585
Adipose-Derived Mesenchymal Stem Cells Improve Acute Liver Injury: A Mechanistic Study Based on the TLR4/MyD88/NF-κB Pathway.
Wang Z, Li M, Yan X, Liu Y, Yang P, Liu W, Guan W
International journal of molecular sciences 2025 Dec 6;26(24)
International journal of molecular sciences 2025 Dec 6;26(24)
Sirtuin 3 promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating macrophage polarization under high glucose.
Lin L, Ren Y, Wang X, Liang H, Yao Q
Scientific reports 2025 Dec 25;16(1):3515
Scientific reports 2025 Dec 25;16(1):3515
The ZFP36-FTO axis is a key regulator of macrophage activation and a druggable therapeutic target of sepsis.
Sarkar R, Wang L, Du J, Blackshear PJ, Li YC
iScience 2025 Dec 19;28(12):114060
iScience 2025 Dec 19;28(12):114060
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Ding R, Hu N, Zhang X, Jiang F, Feng Y, Li Z, Tang S, Li W, Shi H, Si Y
Free radical biology & medicine 2025 Dec 1;240:15-28
Free radical biology & medicine 2025 Dec 1;240:15-28
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
Yu JT, Hu XW, Wang JN, Yang Q, Li XY, Shan RR, Pu T, Hou R, Shen XY, Wang YQ, Zhang F, Yu XW, Wang J, Li FH, Wen JG, Fan Y, Jin J, Jiang YY, Meng XM
Nature communications 2025 Dec 1;17(1):30
Nature communications 2025 Dec 1;17(1):30
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.
Kuang B, Geng N, Yi M, Zeng Q, Fan M, Xian M, Deng L, Chen C, Pan Y, Kuang L, Luo F, Xie Y, Liu C, Deng Z, Nie M, Du Y, Guo F
Journal of advanced research 2025 Aug;74:493-511
Journal of advanced research 2025 Aug;74:493-511
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
Chen P, Gong Q, Wang H, Wang C, Wang W, Wu J, Wu Z, Wang L
Molecular neurobiology 2025 Aug;62(8):10210-10227
Molecular neurobiology 2025 Aug;62(8):10210-10227
Toll-Like Receptor 7 Promotes Periodontal Inflammation and Alveolar Bone Resorption Through the NF-κB Signaling Pathway.
Jing R, Lu J, Wang R, Xiong Z, Yang Y, Luo L
Journal of periodontal research 2025 Aug;60(8):823-834
Journal of periodontal research 2025 Aug;60(8):823-834
Mechanistic Insights into HOTAIR-Driven ADAM17/NF-Κb Activation and Endothelial Dysfunction in LPS-Challenged HUVECs.
He J, Shao Z, Li Z, He Y, Zhang J, Zhong H, Li J, Liu Q, Shao Y
Immunological investigations 2025 Aug;54(6):867-893
Immunological investigations 2025 Aug;54(6):867-893
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Li TT, Guo XF, Zhao YJ, Cheng YH, Xin DQ, Song Y, Liu DX, Wang Z
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
An's anorectal fumigation lotion for nuclear factor kappa-B pathway-targeted treatment of inflammatory mixed hemorrhoids.
Dayong F, Ayue AN, Yuening F, Chunhui W, Zhiyong B, Qian W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):777-785
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):777-785
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy.
Liu X, Xu J, Zheng S, Yang Y, Xie Y, Liu J, Zhong J, Zhang H, Chen J, Dai C, Wang D, Luo J, Chen X, Zhong F, Ye ZC
Pharmacological research 2025 Aug;218:107834
Pharmacological research 2025 Aug;218:107834
Exploration of the Therapeutic Time Window for Thrombectomy in Rat Models of Middle Cerebral Artery Ischemia-Reperfusion.
He Y, Huang P, Li S, Lin J, Ren X, Xiong Y, Yang Y, Hong D
Brain and behavior 2025 Aug;15(8):e70713
Brain and behavior 2025 Aug;15(8):e70713
Targeting CDK1 inhibits Golgi apparatus stress-mediated neuroinflammation and neuronal apoptosis after intracerebral hemorrhage by modulating GRASP55 phosphorylation.
Zhang X, Yang M, Jiang F, Wang Y, Zhou Z, Wu Z
Cellular signalling 2025 Aug;132:111835
Cellular signalling 2025 Aug;132:111835
Decreased excitatory and increased inhibitory transmission in the hippocampal CA1 drive neuroinflammation-induced cognitive impairments in mice.
Wu XM, Shi CN, Liu K, Hu XY, He QL, Yao H, Fan D, Ma DQ, Yang JJ, Shen JC, Ji MH
Brain, behavior, and immunity 2025 Aug;128:416-428
Brain, behavior, and immunity 2025 Aug;128:416-428
T-2 Toxin-Induced Hepatotoxicity in HepG2 Cells Involves the Inflammatory and Nrf2/HO-1 Pathways.
Taroncher M, Franco-Campos F, Rodríguez-Carrasco Y, Ruiz MJ
Toxins 2025 Aug 8;17(8)
Toxins 2025 Aug 8;17(8)
An Olsalazine-Loaded Hollow Mesoporous Prussian Blue/Polydopamine Nanozyme Alleviates Anxiety/Depression-like Behavior and Enhances Brain Neural Activity in Colitis Mice.
Luo Q, Liu D, Yang J, Li T, Sheng H, Liu S, Zhou X, Zhou C, Wang H, Wang Z, Ho CSH
ACS applied materials & interfaces 2025 Aug 6;17(31):44300-44318
ACS applied materials & interfaces 2025 Aug 6;17(31):44300-44318
DEK Interacts with IRE1α to Modulate Endoplasmic Reticulum Stress in Deoxynivalenol-Induced Intestinal Inflammation.
Zeng L, Yu D, Xu J, Qu Z, Wu S, Guo C, Wang K, Lin Z, Lin R, Wen J, Deng Y
Journal of agricultural and food chemistry 2025 Aug 27;73(34):21609-21620
Journal of agricultural and food chemistry 2025 Aug 27;73(34):21609-21620
Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice.
Huang G, Li J, Qin S, Chen X, Liao S, Liu Y, Guo Q, Zeng S, Chen W, Ouyang Q, Long D, Gong F
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 2025 Aug 26;:1-19
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 2025 Aug 26;:1-19
Yuye Jinhua Qingre Tablets Attenuate Acute Pharyngitis by inhibiting the Complement Cascade and C5a/C5aR1 Axis.
Gao Y, You L, Zhou J, Tao X, Jin Z, Wu C, Zhang F, Guo S, Wang H, Guan Y, Luo H, Wu J
Chinese medicine 2025 Aug 25;20(1):134
Chinese medicine 2025 Aug 25;20(1):134
Hybrid molecule SA-10 and its PLGA nanosuspension protect human and rodent retinal ganglion cells against neuronal injury.
Pham JH, Zhang W, Le KT, Kodati B, Amankwa CE, DebNath B, Johnson GA, Bui TT, Gitter RY, Gutierrez JP, Hatfield BR, Satyal R, Sinnott ER, Krishnamoorthy RR, Acharya S, Stankowska DL
BMC neuroscience 2025 Aug 20;26(1):51
BMC neuroscience 2025 Aug 20;26(1):51
2-aminoethoxydiphenylborane intervenes intracellular calcium signaling and attenuates myocardial ischemia-reperfusion injury in mice through ITPR1/MCU pathway.
Bao H, Chen X, Hu X, Cao Z, Zhou W, Chen B, Liao F, Wei F, Huang R, Li W, Chen Z
Scientific reports 2025 Aug 12;15(1):29469
Scientific reports 2025 Aug 12;15(1):29469
Hydrogen protects against autoimmune myocarditis by inhibiting necroptosis via the TNF/TNFR1 signalling pathway.
Pan S, Yu M, Fan B, Wang B, Yang X, Zhang J, Liu X, Hong X, Yang W
Clinical immunology (Orlando, Fla.) 2025 Aug 12;:110577
Clinical immunology (Orlando, Fla.) 2025 Aug 12;:110577
Hepatoprotective effects of polysaccharide from Morchella esculenta are associated with activation of the AMPK/Sirt1 signaling pathway in mice with NAFLD.
Wang D, Zhang M, Zhang Y, Yin Z, Zhang S, Zhao Z, Duan Y
International journal of biological macromolecules 2025 Apr;301:140444
International journal of biological macromolecules 2025 Apr;301:140444
Injectable DMM/GelMA hydrogel for diabetic wound healing via regulating mitochondrial metabolism and macrophage repolarization.
Shao Y, Zhou X, Zhou S, Long J, Jin L, Shi X, Zhou L, Zhang Y, Fan D
Colloids and surfaces. B, Biointerfaces 2025 Apr;248:114488
Colloids and surfaces. B, Biointerfaces 2025 Apr;248:114488
Identifying ENO1 as a protein target of chlorogenic acid to inhibit cellular senescence and prevent skin photoaging in mice.
He X, Wang C, Zhang Q, Yang T, Guo Q, Wang Y, Guo J, Wang P, Zhang J, Tang H, Zhu Y, Wang J
Aging cell 2025 Apr;24(4):e14433
Aging cell 2025 Apr;24(4):e14433
Tmco1-Deficient Mice Exhibit a High Incidence of Otitis Media Associated with Impaired Bone Homeostasis in the Middle Ear.
Dong Y, Ma P, Wang S, Wang L, Chen Y, Zhao F, Yang K, Zhang X, Zhao H, Li B, Geng R, Tang TS, Zheng Q, Zheng T
The American journal of pathology 2025 Apr;195(4):690-704
The American journal of pathology 2025 Apr;195(4):690-704
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Lin L, Wei J, Xue J, Fan G, Zhu W, Zhu Y, Wu R
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
A Smart MMP-9-responsive Hydrogel Releasing M2 Macrophage-derived Exosomes for Diabetic Wound Healing.
Meng H, Su J, Shen Q, Hu W, Li P, Guo K, Liu X, Ma K, Zhong W, Chen S, Ma L, Hao Y, Chen J, Jiang Y, Li L, Fu X, Zhang C
Advanced healthcare materials 2025 Apr;14(10):e2404966
Advanced healthcare materials 2025 Apr;14(10):e2404966
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
Jiang T, Zhu X, Yin Z, Gao R, Li Y, Li C, Meng Q, Zhu X, Song W, Su X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
A novel histone deacetylase inhibitor protects the blood-brain barrier by regulating NF-κB and Nrf2 signaling pathways in OGD/R injury.
Ling L, Zhou G, Zhang X, Mao B, Wan S, Bao Y
Archives of gerontology and geriatrics 2025 Apr;131:105739
Archives of gerontology and geriatrics 2025 Apr;131:105739
Network Pharmacology and In Vitro Experimental Validation Reveal the Anti-Inflammatory and Anti-Apoptotic Effects of Lotus Leaf Extract in Treating Inflammatory Diarrhea in Pigs.
Zheng Y, Zheng J, Wang J, Li J, Liu J, Zheng B, Li Q, Huang X, Lin Z
Current issues in molecular biology 2025 Apr 28;47(5)
Current issues in molecular biology 2025 Apr 28;47(5)
Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier.
Chen Y, Zhou Y, Bai Y, Jia K, Zhang H, Chen Q, Song M, Dai Y, Shi J, Chen Z, Yan X, Shen Y
Neuron 2025 Apr 2;113(7):1082-1097.e8
Neuron 2025 Apr 2;113(7):1082-1097.e8
Wogonoside ameliorates oxidative damage in tubular epithelial cells of diabetic nephropathy by modulating the HNF4A-NRF2 axis.
Li X, Zhao S, Li M, Xing X, Xie J, Wang M, Xu A, Zhao Q, Zhang J
International immunopharmacology 2025 Apr 16;152:114481
International immunopharmacology 2025 Apr 16;152:114481
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
Lv Z, Wang P, Li W, Xie Y, Sun W, Jin X, Jiang R, Fei Y, Liu Y, Shi T, Guo H, Sun Z, Lin J, Wang X, Tan G, Wu Y, Bao N, Shi D
Research (Washington, D.C.) 2024;7:0316
Research (Washington, D.C.) 2024;7:0316
Chitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization.
Wang Q, Dong J, Du M, Liu X, Zhang S, Zhang D, Qin W, Xu X, Li X, Su R, Qiu L, Li B, Yuan H
International journal of nanomedicine 2024;19:2265-2284
International journal of nanomedicine 2024;19:2265-2284
Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway.
Wang D, Wang J, Yin Z, Gong K, Zhang S, Zha Z, Duan Y
International journal of nanomedicine 2024;19:10839-10856
International journal of nanomedicine 2024;19:10839-10856
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, Zhang M, Guo D, Yang X
Drug design, development and therapy 2024;18:13-28
Drug design, development and therapy 2024;18:13-28
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Yang T, Wu P, Jiang L, Chen R, Jin Q, Ye G
Journal of inflammation research 2024;17:8861-8879
Journal of inflammation research 2024;17:8861-8879
Run-Mu-Ling Granules Mitigate Ocular Surface Inflammatory Injury Associated with Dry Eye by Suppressing the NLRP3/GSDMD-Mediated Pyroptosis Pathway.
Luo D, Ji HJ, Yan XQ, Wang ZM, Li LJ, Shi L, Gao WP, Li K
Journal of inflammation research 2024;17:10769-10784
Journal of inflammation research 2024;17:10769-10784
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation.
Qin Y, Gao Y, Wu D, Liu QQ, Su C, Liu G, Yang L, Zhao MG, Yao JY
Frontiers in pharmacology 2024;15:1509482
Frontiers in pharmacology 2024;15:1509482
Celecoxib ameliorates diabetic sarcopenia by inhibiting inflammation, stress response, mitochondrial dysfunction, and subsequent activation of the protein degradation systems.
Deng C, Lu C, Wang K, Chang M, Shen Y, Yang X, Sun H, Yao X, Qiu C, Xu F
Frontiers in pharmacology 2024;15:1344276
Frontiers in pharmacology 2024;15:1344276
Fibroblasts facilitate lymphatic vessel formation in transplanted heart.
Gong H, Wang T, Sun X, Zhang Y, Qiu Y, Sun W, Zhang Y, Teng P, Hu Y, Hu X, Ma L, Xu Q, Zhao H
Theranostics 2024;14(5):1886-1908
Theranostics 2024;14(5):1886-1908
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Wang YH, Chen X, Bai YZ, Gao P, Yang Z, Guo Q, Lu YY, Zheng J, Liu D, Yang J, Tu PF, Zeng KW
Theranostics 2024;14(3):988-1009
Theranostics 2024;14(3):988-1009
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
Shen S, Zhang M, Wang X, Liu Q, Su H, Sun B, Guo Z, Tian B, Gan H, Gong C, Ma L
Theranostics 2024;14(3):1241-1259
Theranostics 2024;14(3):1241-1259
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Sun Y, Wu J, Zhou L, Wang W, Wang H, Sun S, Xu Y, Zhang L, Jiang X, Zhu G, Xi K, Gu Y, Chen L
Frontiers in bioengineering and biotechnology 2024;12:1415527
Frontiers in bioengineering and biotechnology 2024;12:1415527
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury.
Lin J, Sun Y, Xia B, Wang Y, Xie C, Wang J, Hu J, Zhu L
Neuroscience bulletin 2024 Sep;40(9):1230-1244
Neuroscience bulletin 2024 Sep;40(9):1230-1244
Mechanism of Lian Hua Qing Wen capsules regulates the inflammatory response caused by M(1) macrophage based on cellular experiments and computer simulations.
Zong YH, Cao JF, Zhao Y, Gao M, Chen WL, Wu M, Xu X, Xu ZY, Zhang XQ, Tang JZ, Liu Y, Hu XS, Wang SQ, Zhang X
Acta tropica 2024 Sep;257:107320
Acta tropica 2024 Sep;257:107320
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Wu H, Zhang L, Dong X, Yang J, Zheng L, Li L, Liu X, Jin M, Zhang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
oHSV2-mGM repolarizes TAMs and cooperates with αPD1 to reprogram the immune microenvironment of residual cancer after radiofrequency ablation.
Zhu L, Huang J, Zhang S, Cai Q, Guo X, Liu B, Chen L, Zheng C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117060
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117060
Geniposide dosage and administration time: Balancing therapeutic benefits and adverse reactions in liver disease treatment.
Qiu J, Lin C, Ren G, Xu F, Hu T, Le Y, Fan X, Yu Z, Liu Q, Wang X, Dou X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155799
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155799
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
Effects of thyroid hormone on monochromatic light combinations mediate skeletal muscle fiber pattern in broilers.
Liu Y, Wang Z, Cao J, Dong Y, Gao T, Chen Y
Poultry science 2024 Sep;103(9):103999
Poultry science 2024 Sep;103(9):103999
Transferrin-Modified Carprofen Platinum(IV) Nanoparticles as Antimetastasis Agents with Tumor Targeting, Inflammation Inhibition, Epithelial-Mesenchymal Transition Suppression, and Immune Activation Properties.
Zhang M, Chen Y, Feng S, He Y, Liu Z, Zhang N, Wang Q
Journal of medicinal chemistry 2024 Sep 26;67(18):16416-16434
Journal of medicinal chemistry 2024 Sep 26;67(18):16416-16434
Gabapentin alleviates peripheral nerve sensitization induced by inflammatory arthritis via ionotropic glutamate receptor NR2B subunit.
Meng Y, Tan M, Yan Jiang X, Wang T, Li Shen H
Neuroscience 2024 Sep 25;556:1-13
Neuroscience 2024 Sep 25;556:1-13
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Zou C, Cai R, Li Y, Xue Y, Zhang G, Alitongbieke G, Pan Y, Zhang S
iScience 2024 Sep 20;27(9):110766
iScience 2024 Sep 20;27(9):110766
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
Zhang W, Cheng Q, Yin L, Liu Y, Chen L, Jiang Z, Jiang X, Qian S, Li B, Wu M, Yin X, Wang T, Lu Q, Yang T
Chemico-biological interactions 2024 Sep 1;400:111157
Chemico-biological interactions 2024 Sep 1;400:111157
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Zhang X, Hu F, Li J, Chen L, Mao YF, Li QB, Nie CY, Lin C, Xiao J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
Integrating metabolomics and network pharmacology analysis to explore mechanism of Pueraria lobata against pulmonary fibrosis: Involvement of arginine metabolism pathway.
Du H, Shao M, Xu S, Yang Q, Xu J, Ke H, Zou L, Huang L, Cui Y, Qu F
Journal of ethnopharmacology 2024 Oct 5;332:118346
Journal of ethnopharmacology 2024 Oct 5;332:118346
Magnolol Inhibits High Fructose-Induced Podocyte Inflammation via Downregulation of TKFC/Sp1/HDAC4/Notch1 Activation.
Zhou Z, Wang Y, Xing Y, Pan S, Wang W, Yang J, Wu W, Zhou J, Huang L, Liang Q, Zhang D, Kong L
Pharmaceuticals (Basel, Switzerland) 2024 Oct 23;17(11)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 23;17(11)
Oxytocin attenuates neuroinflammation-induced anxiety through restoration of excitation and inhibition balance in the anterior cingulate cortex in mice.
Shi CN, Wu XM, Gao YZ, Ma DQ, Yang JJ, Ji MH
Journal of affective disorders 2024 Oct 1;362:341-355
Journal of affective disorders 2024 Oct 1;362:341-355
Placental ischemia-upregulated angiotensin II type 1 receptor in hypothalamic paraventricular nucleus contributes to hypertension in rat.
Issotina Zibrila A, Zhou J, Wang X, Zeng M, Ali MA, Liu X, Alkuhali AA, Zeng Z, Meng Y, Wang Z, Li X, Liu J
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1677-1691
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1677-1691
Sodium-Glucose Co-Transporter-2 Inhibitor Empagliflozin Attenuates Sorafenib-Induced Myocardial Inflammation and Toxicity.
Liu CH, Ho YC, Lee WC, Huang CY, Lee YK, Hsieh CB, Huang NC, Wu CC, Nguyen NUN, Hsu CC, Chen CH, Chen YC, Huang WC, Lu YY, Fang CC, Chang YC, Chang CL, Tsai MK, Wen ZH, Li CZ, Li CC, Chuang PK, Yang SM, Chu TH, Huang SC
Environmental toxicology 2024 Nov;39(11):4844-4858
Environmental toxicology 2024 Nov;39(11):4844-4858
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
Zhu Z, Song J, Zhang C, Zhang J, Shan Z
Oral diseases 2024 Nov;30(8):5050-5061
Oral diseases 2024 Nov;30(8):5050-5061
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Feng J, Deng X, Hao P, Zhu Z, Li T, Yuan X, Hu J, Wang Y
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
SIRT2 regulates high mobility group protein B1 nucleoplasmic shuttle and degradation via deacetylation in microglia.
Xing WQ, Piao XJ, Han Q, Shi HY, Wu WC, Si F, Lu JJ, Zhou TZ, Guo JR, Li SZ, Xu B
Journal of cellular physiology 2024 Nov;239(11):e31364
Journal of cellular physiology 2024 Nov;239(11):e31364
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction.
Chen YH, Chang YC, Wu WJ, Chen M, Yen CC, Lan YW, Cheng HC, Chen CM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117592
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117592
Oxymatrine alleviates NSAID-associated small bowel mucosal injury by regulating MIP-1/CCR1 signalling and gut microbiota.
Chen M, Zhou H, Shen J, Wei M, Chen Z, Chen X, Fan H, Zhang J, Zhu J
Journal of pharmacological sciences 2024 Nov;156(3):149-160
Journal of pharmacological sciences 2024 Nov;156(3):149-160
Leukocyte Platelet-Rich Plasma-Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization.
Li X, Guo F, Deng J, Li J, Zhang J, Fu M, Fan H
Immunity, inflammation and disease 2024 Nov;12(11):e70064
Immunity, inflammation and disease 2024 Nov;12(11):e70064
Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth.
Yan H, Wang Z, Teng D, Chen X, Zhu Z, Chen H, Wang W, Wei Z, Wu Z, Chai Q, Zhang F, Wang Y, Shu K, Li S, Shi G, Zhu M, Piao HL, Shen X, Bu P
Cell metabolism 2024 Nov 5;36(11):2449-2467.e6
Cell metabolism 2024 Nov 5;36(11):2449-2467.e6
Nobiletin attenuates alcohol-related liver disease by inhibting gut-liver inflammation and gut microbiota disturbance in mice.
Zikela L, Zhu H, Yu Z, Wang D, Li J, Li S, Han Q
European journal of nutrition 2024 Nov 29;64(1):36
European journal of nutrition 2024 Nov 29;64(1):36
Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains.
Bhuiyan P, Zhang W, Chae R, Kim K, St Louis L, Wang Y, Liang G, Wei H
bioRxiv : the preprint server for biology 2024 Nov 25;
bioRxiv : the preprint server for biology 2024 Nov 25;
Dingxian pill alleviates hippocampal neuronal apoptosis in epileptic mice through TNF-α/TNFR1 signaling pathway inhibition.
Wang Q, Qin B, Yu H, Yu H, Zhang X, Li M, Zhou Y, Diao L, Liu H
Journal of ethnopharmacology 2024 Nov 15;334:118579
Journal of ethnopharmacology 2024 Nov 15;334:118579
Gut microbial and metabolomics profiles reveal the potential mechanism of fecal microbiota transplantation in modulating the progression of colitis-associated colorectal cancer in mice.
Song Q, Gao Y, Liu K, Tang Y, Man Y, Wu H
Journal of translational medicine 2024 Nov 15;22(1):1028
Journal of translational medicine 2024 Nov 15;22(1):1028
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Zeng L, Wang Y, Shen J, Wei X, Wu Y, Chi X, Zheng X, Yu X, Shi Y, Liu W
Experimental cell research 2024 Nov 1;443(1):114287
Experimental cell research 2024 Nov 1;443(1):114287
Pesticide metabolite 3, 5, 6-trichloro-2-pyridinol causes massive damage to the cochlea resulting in hearing loss in adult mice.
Huang M, Mao S, Pan Y, Zhang Z, Gui F, Tan X, Hong Y, Chen R
Environmental pollution (Barking, Essex : 1987) 2024 Nov 1;360:124691
Environmental pollution (Barking, Essex : 1987) 2024 Nov 1;360:124691
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
Sun J, Wang X, Xiao J, Yang Q, Huang X, Yang Z, Liu H, Liu Y, Wang H, Huang Z, Ma L, Cao Z
Scientific reports 2024 Nov 1;14(1):26291
Scientific reports 2024 Nov 1;14(1):26291
The association between endothelial function and autoimmune thyroiditis induced by iodine excess.
Wang D, Li P, Zhou Z, Jin M, Li B, Li F, Shen H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127413
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127413
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
Wang J, Wang Z, Zhao Y, Bai L, Wei Y, Huang T, Xu Y, Zhou X
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
Supercritical CO(2) fluid extract from Stellariae Radix ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis by inhibit M1 macrophages polarization via AMPK activation.
Wu W, Song L, Wang H, Feng L, Li Z, Li Y, Li L, Peng L
Environmental toxicology 2024 May;39(5):3188-3197
Environmental toxicology 2024 May;39(5):3188-3197
The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury.
Zhao Y, Li T, Jiang Z, Gai C, Yu S, Xin D, Li T, Liu D, Wang Z
Neural regeneration research 2024 May;19(5):1084-1094
Neural regeneration research 2024 May;19(5):1084-1094
Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury.
Zhao T, Zhong G, Wang Y, Cao R, Song S, Li Y, Wan G, Sun H, Huang M, Bi H, Jiang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308771
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308771
YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
Huang J, Wang X, Li N, Fan W, Li X, Zhou Q, Liu J, Li W, Zhang Z, Liu X, Zeng S, Yang H, Tian M, Yang P, Hou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308031
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308031
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Wang Q, Cheng J, Liu F, Zhu J, Li Y, Zhao Y, Li X, Zhang H, Ju Y, Ma L, Hui X, Lin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Unmasking the dynamics of Mycoplasma gallisepticum: deciphering HD11 macrophage polarization for innovative infection control strategies.
Wang T, Zhao W, Qi Z, Lv S, Xiao Y, Wang Y, Guo Q, Wang L, Peng X
Poultry science 2024 May;103(5):103652
Poultry science 2024 May;103(5):103652
MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.
Liu Y, Hu N, Ai B, Xia H, Li W
BMC cardiovascular disorders 2024 May 30;24(1):286
BMC cardiovascular disorders 2024 May 30;24(1):286
Manual acupuncture ameliorates inflammatory pain by upregulating adenosine A(3) receptor in complete Freund's adjuvant-induced arthritis rats.
Xu JP, Ouyang QW, Shao MJ, Ke H, Du H, Xu SC, Yang Q, Cui YR, Qu F
International immunopharmacology 2024 May 30;133:112095
International immunopharmacology 2024 May 30;133:112095
Purinergic Astrocyte Signaling Driven by TNF-α After Cannabidiol Administration Restores Normal Synaptic Remodeling Following Traumatic Brain Injury.
Ling T, Yin A, Cao Y, Li J, Li H, Zhou Y, Guo X, Li J, Zhang R, Wu H, Li P
Neuroscience 2024 May 3;545:31-46
Neuroscience 2024 May 3;545:31-46
IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis.
Nan Y, Chen M, Wu W, Huang R, Sun W, Lu Q, Gu Z, Mao X, Xu H, Wang Y
Cell death discovery 2024 May 3;10(1):215
Cell death discovery 2024 May 3;10(1):215
Electroacupuncture modulates the TLR4-NF-κB inflammatory signaling pathway to attenuate ocular surface inflammation in dry eyes of type 2 diabetic rats.
Fu Z, Wan M, Jin T, Lai S, Li X, Sun X, Gao W
Cellular and molecular biology (Noisy-le-Grand, France) 2024 May 27;70(5):111-118
Cellular and molecular biology (Noisy-le-Grand, France) 2024 May 27;70(5):111-118
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury.
Zhang Y, Wang X, Ji Y, Hong H, Geng X, Zhang K, Fu Z, Cai G, Chen X, Li P, Hong Q
Cell communication and signaling : CCS 2024 May 27;22(1):291
Cell communication and signaling : CCS 2024 May 27;22(1):291
Shengjihuayu formula ameliorates the oxidative injury in human keratinocytes via blocking JNK/c-Jun/MMPs signaling pathway.
Sun L, Yin H, Li YT, Qiao YX, Wang J, He QY, Xiao ZW, Kuai L, Xiang YW
Journal of ethnopharmacology 2024 May 23;326:117938
Journal of ethnopharmacology 2024 May 23;326:117938
Mechanic study based on untargeted metabolomics of Pi-pa-run-fei-tang on pepper combined with ammonia induced chronic cough model mice.
Jie XL, Tong ZR, Xu XY, Wu JH, Jiang XL, Tao Y, Feng PS, Yu J, Lan JP, Wang P
Journal of ethnopharmacology 2024 May 23;326:117905
Journal of ethnopharmacology 2024 May 23;326:117905
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Song J, Bai H, Chen S, Xing Y, Lou J
Heliyon 2024 May 15;10(9):e30422
Heliyon 2024 May 15;10(9):e30422
Resveratrol attenuates inflammation and fibrosis in rheumatoid arthritis-associated interstitial lung disease via the AKT/TMEM175 pathway.
Liu N, Fan X, Shao Y, Chen S, Wang T, Yao T, Chen X
Journal of translational medicine 2024 May 14;22(1):457
Journal of translational medicine 2024 May 14;22(1):457
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.
Li H, Ni H, Li Y, Zhou A, Qin X, Li Y, Che L, Mo H, Qin C, Li J
Cell death discovery 2024 May 13;10(1):227
Cell death discovery 2024 May 13;10(1):227
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA
Cell communication and signaling : CCS 2024 May 10;22(1):263
Cell communication and signaling : CCS 2024 May 10;22(1):263
Self-assembly of PEG-PPS polymers and LL-37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic wound healing.
Shi R, Qiao J, Sun Q, Hou B, Li B, Zheng J, Zhang Z, Peng Z, Zhou J, Shen B, Deng J, Zhang X
Bioengineering & translational medicine 2024 Mar;9(2):e10619
Bioengineering & translational medicine 2024 Mar;9(2):e10619
Single-Cell Transcriptomics Reveals the Ameliorative Effect of Oridonin on Septic Liver Injury.
Liu J, Zhang Q, Wong YK, Luo P, Chen J, Xie L, Chen J, He X, Shi F, Gong P, Liu X, Wang J
Advanced biology 2024 Mar;8(3):e2300542
Advanced biology 2024 Mar;8(3):e2300542
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Yan C, Liu Z, Xie W, Zhang T, Zhang J, Li G, Xu X, Ye L, Gong J
Experimental neurology 2024 Mar;373:114672
Experimental neurology 2024 Mar;373:114672
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
Oral delivery of miR-146a-5p overexpression plasmid-loaded Pickering double emulsion modulates intestinal inflammation and the gut microbe.
Zhu J, Fan Y, Yang S, Qin M, Chen X, Luo J, Chen T, Sun J, Zhang Y, Xi Q
International journal of biological macromolecules 2024 Mar;261(Pt 2):129733
International journal of biological macromolecules 2024 Mar;261(Pt 2):129733
Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway.
Li G, Liu X, Sun X, Huang L, Kuang W, Ou J, Zhang J, Zhang Z, Li H, Tang H, Feng C, Gu L, Yang C, Peili W, Wang J
Environment international 2024 Mar;185:108543
Environment international 2024 Mar;185:108543
S100A9(-/-) alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFκB signaling axis.
Gong C, Ma J, Deng Y, Liu Q, Zhan Z, Gan H, Xiang X, Zhang M, Cao K, Shen T, Fang L, Shen B, Shen S, Ding S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116233
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116233
Nrf-2/ROS/NF-κB pathway is modulated by cynarin in human mesenchymal stem cells in vitro from ankylosing spondylitis.
Song C, Wang K, Qian B, Lu J, Qiao M, Qiu Y, Wang B, Yu Y
Clinical and translational science 2024 Mar;17(3):e13748
Clinical and translational science 2024 Mar;17(3):e13748
Novel mechanism of Clostridium butyricum alleviated coprophagy prevention-induced intestinal inflammation in rabbit.
Li Z, He H, Chen M, Ni M, Guo C, Wan Z, Zhou J, Wang Z, Wang Y, Cai H, Li M, Sun H, Xu H
International immunopharmacology 2024 Mar 30;130:111773
International immunopharmacology 2024 Mar 30;130:111773
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134
iScience 2024 Mar 15;27(3):109134
IL-22 promotes occludin expression by activating autophagy and treats ulcerative colitis.
Nong H, Yuan H, Lin Y, Chen S, Li Y, Luo Z, Yang W, Zhang T, Chen Y
Molecular and cellular biochemistry 2024 Jun;479(6):1443-1450
Molecular and cellular biochemistry 2024 Jun;479(6):1443-1450
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Dual cross-linked self-healing hydrogel enhanced by dopamine nanoparticles and raffinose for wound healing.
Wang Y, Gao H, Wang X, Li D, Zhang W, Meng X, Wang L, Zhu T, Dong P, Chen Y, Meng X
International journal of biological macromolecules 2024 Jun;271(Pt 1):132615
International journal of biological macromolecules 2024 Jun;271(Pt 1):132615
Scutellarin alleviates microglia-mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathway.
Duan Z, Chen H, Miao W, He J, Xu D, Qi Z, Yang L, Jia W, Wu C
Journal of cell communication and signaling 2024 Jun;18(2):e12023
Journal of cell communication and signaling 2024 Jun;18(2):e12023
Gut microbiota mediates the protective effects of β-hydroxybutyrate against cisplatin-induced acute kidney injury.
Tian R, Wang X, Tang S, Zhao L, Hao Y, Li R, Zhou X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116752
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116752
Associations of cold-inducible RNA-binding protein with bacterial load, proinflammatory cytokines and mortality from pneumonia.
Guo Q, Li HY, Zeng C, Lü ZD, Jiang M
Clinical and translational science 2024 Jun;17(6):e13850
Clinical and translational science 2024 Jun;17(6):e13850
Development and Investigation of an Innovative 3D Biohybrid Based on Collagen and Silk Sericin Enriched with Flavonoids for Potential Wound Healing Applications.
Sleiman L, Lazăr Popa AD, Albu-Kaya M, Marin MM, Kaya DA, Vasile OR, Dinescu S
Polymers 2024 Jun 8;16(12)
Polymers 2024 Jun 8;16(12)
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis.
Wang YH, Gao P, Wang YQ, Xu LZ, Zeng KW, Tu PF
European journal of pharmacology 2024 Jun 5;972:176551
European journal of pharmacology 2024 Jun 5;972:176551
Cancerous Conditions Accelerate the Aging of Skeletal Muscle via Mitochondrial DNA Damage.
Luo Y, Fujiwara-Tani R, Kawahara I, Goto K, Nukaga S, Nishida R, Nakashima C, Sasaki T, Miyagawa Y, Ogata R, Fujii K, Ohmori H, Kuniyasu H
International journal of molecular sciences 2024 Jun 27;25(13)
International journal of molecular sciences 2024 Jun 27;25(13)
Evaluation of Cross-Talk and Alleviate Potential of Cytotoxic Factors Induced by Deoxynivalenol in IPEC-J2 Cells Interference with Curcumin.
Wang Q, Li A, Yu H, Wang C, Wang T, Zhang J
International journal of molecular sciences 2024 Jun 26;25(13)
International journal of molecular sciences 2024 Jun 26;25(13)
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
Jiang F, Xu C, Fan X, Yang S, Fan W, Li M, Song J, Wei W, Chen H, Zhong D, Li G
Neuroscience 2024 Jun 21;549:121-137
Neuroscience 2024 Jun 21;549:121-137
A bioenergetically-active ploy (glycerol sebacate)-based multiblock hydrogel improved diabetic wound healing through revitalizing mitochondrial metabolism.
Qi X, Liu C, Si J, Yin B, Huang J, Wang X, Huang J, Sun H, Zhu C, Zhang W
Cell proliferation 2024 Jul;57(7):e13613
Cell proliferation 2024 Jul;57(7):e13613
The role of serum/glucocorticoid-regulated kinase 1 in brain function following cerebral ischemia.
Wu CY, Zhang Y, Xu L, Huang Z, Zou P, Clemons GA, Li C, Citadin CT, Zhang Q, Lee RH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Jul;44(7):1145-1162
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Jul;44(7):1145-1162
Macrophage ATG16L1 expression suppresses metabolic dysfunction-associated steatohepatitis progression by promoting lipophagy.
Wang Q, Bu Q, Xu Z, Liang Y, Zhou J, Pan Y, Zhou H, Lu L
Clinical and molecular hepatology 2024 Jul;30(3):515-538
Clinical and molecular hepatology 2024 Jul;30(3):515-538
Protective Role of MerTK in Diabetic Peripheral Neuropathy via Inhibition of the NF-κB Signaling Pathway.
Su X, Chen W, Fu Y, Wu B, Mao F, Zhao Y, Yang Q, Lan D
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2024 Jul;132(7):396-406
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2024 Jul;132(7):396-406
Disulfiram downregulates ferredoxin 1 to maintain copper homeostasis and inhibit inflammation in cerebral ischemia/reperfusion injury.
Yang S, Li X, Yan J, Jiang F, Fan X, Jin J, Zhang W, Zhong D, Li G
Scientific reports 2024 Jul 2;14(1):15175
Scientific reports 2024 Jul 2;14(1):15175
Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes.
Lin Y, Tang Y, Yi O, Zhu J, Su Z, Li G, Zhou H, Liu L, Liu B, Cai X
Journal of nanobiotechnology 2024 Jul 1;22(1):383
Journal of nanobiotechnology 2024 Jul 1;22(1):383
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Zhao T, Zhou Y, Zhang D, Han D, Ma J, Li S, Li T, Hu S, Li Z
Brain research 2024 Jul 1;1834:148907
Brain research 2024 Jul 1;1834:148907
NADase CD38 is a key determinant of ovarian aging.
Yang Q, Chen W, Cong L, Wang M, Li H, Wang H, Luo X, Zhu J, Zeng X, Zhu Z, Xu Y, Lei M, Zhao Y, Wei C, Sun Y
Nature aging 2024 Jan;4(1):110-128
Nature aging 2024 Jan;4(1):110-128
CircIRAK3 exerts negative feedback regulation on inflammation by binding to HNRNP U and destabilizing proinflammatory cytokine mRNA in osteoarthritis and chondrogenesis.
Wen X, Fang G, Li H, Jiang Z, Du X, Liao Z, Liu R, Huang G, Meng F, Liao W, Zhang Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128453
International journal of biological macromolecules 2024 Jan;256(Pt 2):128453
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Lang Y, Wang Q, Sheng Q, Lu S, Yang M, Kong Z, Gao Y, Fan X, Shen N, Wang R, Lv Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling.
Li HY, Liu DS, Li LB, Zhang YB, Dong HY, Rong H, Zhang JY, Wang JP, Jin M, Luo N, Zhang XJ
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117319
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117319
Pyrolae herba alleviates cognitive impairment via hippocampal TREM2 signaling modulating neuroinflammation and neurogenesis in lipopolysaccharide-treated mice.
Sun Y, Zhang H, Liu R, Huang R, Zhang X, Zhou S, Wu L, Zhu B, Wu H
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117214
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117214
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
Feng H, Yang L, Yang H, Cheng D, Li M, Song E, Xu T
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis.
Yuan S, Wang Y, Yang J, Tang Y, Wu W, Meng X, Jian Y, Lei Y, Liu Y, Tang C, Zhao Z, Zhao F, Liu W
Aging 2024 Jan 29;16(2):1374-1389
Aging 2024 Jan 29;16(2):1374-1389
Mesencephalic astrocyte-derived neurotrophic factor (MANF) alleviates cerebral ischemia/reperfusion injury in mice by regulating microglia polarization via A20/NF-κB pathway.
Zhao X, Wang Z, Wang J, Xu F, Zhang Y, Han D, Fang W
International immunopharmacology 2024 Jan 25;127:111396
International immunopharmacology 2024 Jan 25;127:111396
Preventive effect of low-carbohydrate high-fat dietary pattern on liver disease caused by alcohol consumption via a 6pgd-involved mechanism in mice.
Qiu J, Dong F, Zhuge H, Han Q, Li J, Guo R, Dou X, Li J, Li S
Food & function 2024 Jan 22;15(2):732-746
Food & function 2024 Jan 22;15(2):732-746
Zinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4/NF-κB pathway in meat ducks.
Chang Y, Wang K, Liu G, Zhao H, Chen X, Cai J, Jia G
Journal of animal science and biotechnology 2024 Jan 19;15(1):5
Journal of animal science and biotechnology 2024 Jan 19;15(1):5
Increased Circulating IL-32 Is Associated With Placenta Macrophage-derived IL-32 and Gestational Diabetes Mellitus.
Huang X, Li Y, Tong X, Wu Y, Zhang R, Sheng L, Xu J, Yu Z, Chen Z, Sun T, Wang F, Yang Q, Li Z, Gao C, Ma L, Ding H, Zang S, Yang N, Zhang TN, Liu J
The Journal of clinical endocrinology and metabolism 2024 Jan 18;109(2):333-343
The Journal of clinical endocrinology and metabolism 2024 Jan 18;109(2):333-343
Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation.
Zhang Y, Qi Y, Jia Z, Li Y, Wu L, Zhou Q, Xu F
Chinese medicine 2024 Jan 11;19(1):8
Chinese medicine 2024 Jan 11;19(1):8
Effect of Infliximab on Radiation-Induced Submandibular Gland Dysfunction in Rats.
Zhang P, Abudunaibi M, Zhao Q, Wu Y, Aihaiti G, Wu S, Qi J, Shi L, Xu H
Radiation research 2024 Jan 1;201(1):77-86
Radiation research 2024 Jan 1;201(1):77-86
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Xu H, Fu J, Tu Q, Shuai Q, Chen Y, Wu F, Cao Z
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes.
Lin S, Chen Z, Wu Z, Fei F, Xu Z, Tong Y, Sun W, Wang P
Neurochemical research 2024 Feb;49(2):477-491
Neurochemical research 2024 Feb;49(2):477-491
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
Yang J, Zhang L, Sun S, Zhang S, Ding Q, Chai G, Yu W, Zhao T, Shen L, Gao Y, Liu W, Ding C
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion.
Huang Y, Zheng J, Zeng G, Xu H, Lv Y, Liang X, Jin L, Jiang X
Materials today. Bio 2024 Feb;24:100931
Materials today. Bio 2024 Feb;24:100931
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Zhang J, Xie W, Ni B, Li Z, Feng D, Zhang Y, Han Q, Zhou H, Gu M, Tan R
Pharmacological research 2024 Feb;200:107051
Pharmacological research 2024 Feb;200:107051
Fibroblast growth factor 21 alleviates unilateral ureteral obstruction-induced renal fibrosis by inhibiting Wnt/β-catenin signaling pathway.
Zhong W, Jiang Y, Wang H, Luo X, Zeng T, Huang H, Xiao L, Jia N, Li A
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119620
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119620
Early life stress enhances the susceptibility to depression and interferes with neuroplasticity in the hippocampus of adolescent mice via regulating miR-34c-5p/SYT1 axis.
Yu S, Zhao Y, Luo Q, Gu B, Wang X, Cheng J, Wang Z, Liu D, Ho RCM, Ho CSH
Journal of psychiatric research 2024 Feb;170:262-276
Journal of psychiatric research 2024 Feb;170:262-276
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Shi C, Zhang Y, Wu G, Zhu Z, Zheng H, Sun X, Heng Y, Pan S, Xiu H, Zhang J, Yin Z, Yu Z, Liang B
Advanced healthcare materials 2024 Feb;13(4):e2302626
Advanced healthcare materials 2024 Feb;13(4):e2302626
Rosavin Alleviates LPS-Induced Acute Lung Injure by Modulating the TLR-4/NF-κB/MAPK Singnaling Pathways.
Liu QH, Zhang K, Feng SS, Zhang LJ, Li SY, Wang HY, Wang JH
International journal of molecular sciences 2024 Feb 3;25(3)
International journal of molecular sciences 2024 Feb 3;25(3)
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
Liu PY, Hong KF, Liu YD, Sun ZY, Zhao TT, Li XL, Lao CC, Tan SF, Zhang HY, Zhao YH, Xie Y, Xu YH
Chinese medicine 2024 Feb 16;19(1):27
Chinese medicine 2024 Feb 16;19(1):27
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Xie W, Li F, Han Y, Chi X, Qin Y, Ye F, Li Z, Xiao J
Heliyon 2024 Feb 15;10(3):e25906
Heliyon 2024 Feb 15;10(3):e25906
Suppressing inflammatory signals and apoptosis-linked sphingolipid metabolism underlies therapeutic potential of Qing-Jin-Hua-Tan decoction against chronic obstructive pulmonary disease.
Yang J, Shen X, Qin M, Zhou P, Huang FH, You Y, Wang L, Wu JM
Heliyon 2024 Feb 15;10(3):e24336
Heliyon 2024 Feb 15;10(3):e24336
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
Lei Y, Chen Y, Wang S, Lin Z, Han P, Tian D, Wang H, Liu M
Experimental animals 2024 Feb 14;73(1):83-92
Experimental animals 2024 Feb 14;73(1):83-92
Exploring the therapeutic potential of puerarin on intervertebral disc degeneration by regulating apoptosis of nucleus pulposus cells.
Wang X, Song C, Zhou D, Mei Y, Cai W, Chen R, Lv J, Shi H, Liu Z
JOR spine 2024 Dec;7(4):e70020
JOR spine 2024 Dec;7(4):e70020
Hypothermic oxygenated perfusion inhibits CLIP1-mediated TIRAP ubiquitination via TFPI2 to reduce ischemia‒reperfusion injury of the fatty liver.
Yue P, Lv X, Cao H, Zou Y, You J, Luo J, Lu Z, Chen H, Liu Z, Zhong Z, Xiong Y, Fan X, Ye Q
Experimental & molecular medicine 2024 Dec;56(12):2588-2601
Experimental & molecular medicine 2024 Dec;56(12):2588-2601
Amitraz mechanisms of cytotoxicity in a characterized SH-SY5Y cells spheroid model.
Franco-Campos F, Fernández-Franzón M, Rodríguez-Carrasco Y, Ruiz MJ
Toxicology 2024 Dec;509:153987
Toxicology 2024 Dec;509:153987
TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway.
Kong J, Zhang Q, Zheng H, Tang D, Fang L, An S, Li J, Fan Z
Experimental neurology 2024 Dec;382:114975
Experimental neurology 2024 Dec;382:114975
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Wang Y, Yang X, Liu M, Yan Y, Kong F, Wang J, Zhang Z, Chen Y, Chen L, Liang Z, Peng X, Liu F
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
An injectable self-lubricating supramolecular polymer hydrogel loaded with platelet lysate to boost osteoarthritis treatment.
Zhang P, Yang J, Wang Z, Wang H, An M, Yakufu M, Wang W, Liu Y, Liu W, Li C
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:20-36
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:20-36
Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly.
Padilla-Lopategui S, Ligorio C, Bu W, Yin C, Laurenza D, Redondo C, Owen R, Sun H, Rose FRAJ, Iskratsch T, Mata A
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(52):e2407156
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(52):e2407156
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
Chen SD, Chu CY, Wang CB, Yang Y, Xu ZY, Qu YL, Man Y
Biomaterials 2024 Dec;311:122685
Biomaterials 2024 Dec;311:122685
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Zhu T, Chen J, Zhang M, Tang Z, Tong J, Hao X, Li H, Xu J, Yang J
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Xu S, Zhang M, Wang R, Zhang J, Wang C, Xie L, Zhao W
Acta biomaterialia 2024 Dec;190:273-292
Acta biomaterialia 2024 Dec;190:273-292
Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice.
Xie D, Zhong S, Luo M, Xu J, Zheng R, Luo J, Wang Y, Guo Y, Guo L, Wu B, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156235
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156235
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
Pang J, Yin L, Jiang W, Wang H, Cheng Q, Jiang Z, Cao Y, Zhu X, Li B, Qian S, Yin X, Wang T, Lu Q, Yang T
Cellular signalling 2024 Dec;124:111478
Cellular signalling 2024 Dec;124:111478
Breaking the boundaries of wound closure: A novel polyurethane tissue adhesive with enhanced healing properties.
Zhou Q, Shi Z, Xia L, Mi J, Zhang Y, Xu X, Pan J
Journal of biomedical materials research. Part A 2024 Dec;112(12):2301-2313
Journal of biomedical materials research. Part A 2024 Dec;112(12):2301-2313
Toralactone alleviates cisplatin-induced acute kidney injury by modulating the gut microbiota-renal axis.
Tian Y, Tian R, He J, Guo Y, Yan P, Chen Y, Li R, Wang B
International immunopharmacology 2024 Dec 5;142(Pt A):113115
International immunopharmacology 2024 Dec 5;142(Pt A):113115
Role of MYO1F in neutrophil and macrophage recruitment and pro-inflammatory cytokine production in Aspergillus fumigatus keratitis.
Liu W, Yang H, Xu Q, Lee J, Sun J, Xue S, Yang X, Sun X, Che C
International immunopharmacology 2024 Dec 5;142(Pt A):113094
International immunopharmacology 2024 Dec 5;142(Pt A):113094
Cardioprotective effect of Saussurea involucrata injection against Doxorubicin-induced cardiotoxicity by network pharmacology analysis and experimental verification.
Wang D, Jin Y, Yang M, Xue Y, Zhang X, Guo Y, Li X, Ma K
Acta biochimica et biophysica Sinica 2024 Dec 4;57(4):554-568
Acta biochimica et biophysica Sinica 2024 Dec 4;57(4):554-568
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Li J, Tian Z, Zhang T, Jin J, Zhang X, Xie P, Lin H, Gu J, Wu Y, Wang X, Zhang S, Yan X, Guo D, Wang Z, Zhang Q
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Cellular & molecular biology letters 2024 Dec 3;29(1):148
ATP citrate lyase ablation hampers exocrine regeneration via TLR4/NF-kappaB signaling after acute pancreatitis in mice.
Hong YP, Yan X, Ding QZ, Zhang ZB
International immunopharmacology 2024 Dec 25;143(Pt 3):113485
International immunopharmacology 2024 Dec 25;143(Pt 3):113485
Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.
Ma Y, Fei S, Chen X, Gui Y, Zhou B, Xiang T, Liu J, Yue K, Li Q, Jiang W, Sun C, Huang X
Communications biology 2024 Dec 19;7(1):1679
Communications biology 2024 Dec 19;7(1):1679
Discovery of the synergy between sulindac and NO expands the application of NSAIDs in cardiac complications.
Zhou W, Jiang P, Wang C, Gou S
Bioorganic & medicinal chemistry 2024 Dec 15;116:117991
Bioorganic & medicinal chemistry 2024 Dec 15;116:117991
Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice.
Bhuiyan P, Zhang W, Liang G, Jiang B, Vera R, Chae R, Kim K, Louis LS, Wang Y, Liu J, Chuang DM, Wei H
bioRxiv : the preprint server for biology 2024 Dec 12;
bioRxiv : the preprint server for biology 2024 Dec 12;
Exosomes from human bone marrow MSCs alleviate PD-1/PD-L1 inhibitor-induced myocardial injury in melanoma mice by regulating macrophage polarization and pyroptosis.
Zhou B, Qin Q, Fang Y, Liu X, Zhang M, Wang S, Zhong L, Guo R
Life sciences 2024 Dec 1;358:123108
Life sciences 2024 Dec 1;358:123108
A New Modulator of Neuroinflammation in Diabetic Retinopathy: USP25.
Hu Q, Zhang X, Peng H, Guan J, Huang Z, Jiang B, Sun D
Inflammation 2024 Aug;47(4):1520-1535
Inflammation 2024 Aug;47(4):1520-1535
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Wang Y, Li H, Sun H, Xu C, Sun H, Wei W, Song J, Jia F, Zhong D, Li G
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-κB/MAPK pathways via binding to TAK1.
Li B, Hu Y, Chen Y, Liu K, Rong K, Hua Q, Fu S, Yang X, Zhou T, Cheng X, Zhang K, Zhao J
Biochemical pharmacology 2024 Aug;226:116389
Biochemical pharmacology 2024 Aug;226:116389
SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure.
Li H, Wan L, Liu M, Ma E, Huang L, Yang Y, Li Q, Fang Y, Li J, Han B, Zhang C, Sun L, Hou X, Li H, Sun M, Qian S, Duan X, Zhao R, Yang X, Chen Y, Wu S, Zhang X, Zhang Y, Cheng G, Chen G, Gao Q, Xu J, Hou L, Wei C, Zhong H
PLoS pathogens 2024 Aug;20(8):e1012291
PLoS pathogens 2024 Aug;20(8):e1012291
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Yang C, Xu T, Lu Y, Liu J, Chen C, Wang H, Chen X
Neuroscience 2024 Aug 6;552:14-28
Neuroscience 2024 Aug 6;552:14-28
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Yan Q, Song C, Liu H, Li Y, Ma J, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z
International immunopharmacology 2024 Aug 20;137:112448
International immunopharmacology 2024 Aug 20;137:112448
Exploring the mechanism of Lianhuaqingwen (LHQW) in treating chronic bronchitis based on network pharmacology and experimental validation.
Lin S, Wang S, Jiang Q, Liu S, Liu S, Cai T
Respiratory research 2024 Aug 2;25(1):294
Respiratory research 2024 Aug 2;25(1):294
IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction.
Deng Y, Pang X, Chen L, Peng W, Huang X, Huang P, Zhao S, Li Z, Cai X, Huang Q, Zeng J, Feng Y, Chen B
iScience 2024 Aug 16;27(8):110568
iScience 2024 Aug 16;27(8):110568
GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease.
Li H, Cao X, Gu X, Dong M, Huang L, Mao C, Xia S, Yang H, Bao X, Yang Y, Xu Y
Neuroscience bulletin 2024 Apr;40(4):451-465
Neuroscience bulletin 2024 Apr;40(4):451-465
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
Zhao C, Yu Y, Yin G, Xu C, Wang J, Wang L, Zhao G, Ni S, Zhang H, Zhou B, Wang Y
Inflammopharmacology 2024 Apr;32(2):1277-1294
Inflammopharmacology 2024 Apr;32(2):1277-1294
A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function.
Chen S, Barnstable CJ, Zhang X, Li X, Zhao S, Tombran-Tink J
The ocular surface 2024 Apr;32:1-12
The ocular surface 2024 Apr;32:1-12
Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway.
Liu Y, Sun Z, Dong R, Liu P, Zhang X, Li Y, Lai X, Cheong HF, Wu Y, Wang Y, Zhou H, Gui D, Xu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155437
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155437
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Tan P, Cai S, Huang Z, Li M, Liu S, Chen J, Fu W, Zhao L
Cellular signalling 2024 Apr;116:111033
Cellular signalling 2024 Apr;116:111033
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Liu B, Xian Y, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B, Jiang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Neuroprotective effect of tanshinone IIA-modified mesenchymal stem cells in a lipopolysaccharide-induced neuroinflammation model.
Wu J, Chen J, Ge Y, Huang N, Luo Y
Heliyon 2024 Apr 30;10(8):e29424
Heliyon 2024 Apr 30;10(8):e29424
Biomimetic nanoparticles for effective Celastrol delivery to targeted treatment of rheumatoid arthritis through the ROS-NF-κB inflammasome axis.
Wang B, Shen J, Wang X, Hou R
International immunopharmacology 2024 Apr 20;131:111822
International immunopharmacology 2024 Apr 20;131:111822
Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway.
Rao Y, Li J, Qiao R, Luo J, Liu Y
International immunopharmacology 2024 Apr 20;131:111686
International immunopharmacology 2024 Apr 20;131:111686
Muscone inhibits the progression of atherosclerotic plaques in mice aorta by inhibiting the NF-κB/p65 pathway.
Li L, Zhuang S, Jiang S
Biochemical and biophysical research communications 2024 Apr 2;702:149628
Biochemical and biophysical research communications 2024 Apr 2;702:149628
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis.
Zhang D, Li Z, Gao Y, Sun H
Aging 2024 Apr 19;16(8):7277-7292
Aging 2024 Apr 19;16(8):7277-7292
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Dilxat T, Shi Q, Chen X, Liu X
Aging 2024 Apr 12;16(7):6521-6536
Aging 2024 Apr 12;16(7):6521-6536
Increased serum levels of high-mobility group box 1 protein and the location characteristics in the patients of intracranial aneurysms.
Lyu Y, Tu H, Luo J, Wang C, Li A, Zhou Y, Zhao J, Wang H, Hu J
Brain research 2024 Apr 1;1828:148759
Brain research 2024 Apr 1;1828:148759
Integrated Proteomic and Phosphoproteomic Analysis of the Hippocampus in a Mouse Model of Early Life Inflammation.
Wu XM, Gao YZ, Zhu TT, Gu HW, Tong JH, Sun J, Yang JJ, Ji MH
Neuroimmunomodulation 2023;30(1):28-41
Neuroimmunomodulation 2023;30(1):28-41
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC
International journal of biological sciences 2023;19(1):294-310
International journal of biological sciences 2023;19(1):294-310
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Fan Y, Yang Y, Lin K, Zhou X, Li Y, Lin Q
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
An JR, Liu JT, Gao XM, Wang QF, Sun GY, Su JN, Zhang C, Yu JX, Yang YF, Shi Y
Frontiers in cellular neuroscience 2023;17:1136070
Frontiers in cellular neuroscience 2023;17:1136070
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
Wan MM, Jin T, Fu ZY, Lai SH, Gao WP
Journal of pain research 2023;16:4241-4252
Journal of pain research 2023;16:4241-4252
Curcumin Alleviates Epidermal Psoriasis-Like Dermatitis and IL-6/STAT3 Pathway of Mice.
Cai Z, Zeng Y, Liu Z, Zhu R, Wang W
Clinical, cosmetic and investigational dermatology 2023;16:2399-2408
Clinical, cosmetic and investigational dermatology 2023;16:2399-2408
Characterisation of macrophage infiltration and polarisation based on integrated transcriptomic and histological analyses in Primary Sjögren's syndrome.
Zong Y, Yang Y, Zhao J, Li L, Luo D, Hu J, Gao Y, Wei L, Li N, Jiang L
Frontiers in immunology 2023;14:1292146
Frontiers in immunology 2023;14:1292146
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Zhang RB, Dong LC, Shen Y, Li HY, Huang Q, Yu SG, Wu QF
Frontiers in immunology 2023;14:1187574
Frontiers in immunology 2023;14:1187574
Diabetes mellitus induces a novel inflammatory network involving cancer progression: Insights from bioinformatic analysis and in vitro validation.
Tan Y, Kang J, Li H, Zhong A, Liu Y, Zhang Z, Huang R, Cheng X, Peng W
Frontiers in immunology 2023;14:1149810
Frontiers in immunology 2023;14:1149810
Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis in atherogenic diet-fed ApoE (-/-) knockout mice.
Chang GR, Cheng WY, Fan HC, Chen HL, Lan YW, Chen MS, Yen CC, Chen CM
Frontiers in cell and developmental biology 2023;11:1158812
Frontiers in cell and developmental biology 2023;11:1158812
Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model.
Song X, Leonhard WN, Kanhai AA, Steinberg GR, Pei Y, Peters DJM
Frontiers in molecular biosciences 2023;10:1058825
Frontiers in molecular biosciences 2023;10:1058825
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
Chen Y, Lei Y, Wang H, Wang L, Xu J, Wang S, Yu M, Peng Z, Xiao F, Tian D, Liu M
International journal of molecular medicine 2023 Sep;52(3)
International journal of molecular medicine 2023 Sep;52(3)
Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate.
He XL, Chen JY, Feng YL, Song P, Wong YK, Xie LL, Wang C, Zhang Q, Bai YM, Gao P, Luo P, Liu Q, Liao FL, Li ZJ, Jiang Y, Wang JG
Acta pharmacologica Sinica 2023 Sep;44(9):1801-1814
Acta pharmacologica Sinica 2023 Sep;44(9):1801-1814
Puerarin inhibits inflammation and lipid accumulation in alcoholic liver disease through regulating MMP8.
Hu Y, Wang S, Wu L, Yang K, Yang F, Yang J, Hu S, Yao Y, Xia X, Liu Y, Peng L, Wan J, Shen C, Xu T
Chinese journal of natural medicines 2023 Sep;21(9):670-681
Chinese journal of natural medicines 2023 Sep;21(9):670-681
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Gong H, Han D, Luo Z, Zhu Q, Zhu X, Liu S, Chen D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Zhang T, Zhang Y, Li S, Ge H, Song Q, Zhang Y, Yang G, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Rescuing Nucleus Pulposus Cells From Senescence via Dual-Functional Greigite Nanozyme to Alleviate Intervertebral Disc Degeneration.
Shi Y, Li H, Chu D, Lin W, Wang X, Wu Y, Li K, Wang H, Li D, Xu Z, Gao L, Li B, Chen H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300988
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300988
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Tang H, Li H, Li D, Peng J, Zhang X, Yang W
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Dandelion Polysaccharides Ameliorate High-Fat-Diet-Induced Atherosclerosis in Mice through Antioxidant and Anti-Inflammatory Capabilities.
Zhou S, Wang Z, Hao Y, An P, Luo J, Luo Y
Nutrients 2023 Sep 24;15(19)
Nutrients 2023 Sep 24;15(19)
Combining idebenone and rosuvastatin prevents atherosclerosis by suppressing oxidative stress and NLRP3 inflammasome activation.
Yu W, Jiang W, Wu W, Wang G, Zhao D, Yan C, Lin P
European journal of pharmacology 2023 Sep 15;955:175911
European journal of pharmacology 2023 Sep 15;955:175911
Single-cell RNA sequencing reveals the effects of capsaicin in the treatment of sepsis-induced liver injury.
Zhang Q, Liu J, Shen J, Ou J, Wong YK, Xie L, Huang J, Zhang C, Fu C, Chen J, Chen J, He X, Shi F, Luo P, Gong P, Liu X, Wang J
MedComm 2023 Oct;4(5):e395
MedComm 2023 Oct;4(5):e395
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2.
Li Z, Liu B, Lambertsen KL, Clausen BH, Zhu Z, Du X, Xu Y, Poulsen FR, Halle B, Bonde C, Chen M, Wang X, Schlüter D, Huang J, Waisman A, Song W, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301641
Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis.
van Eijs MJM, Ter Linde JJM, Baars MJD, Amini M, Laclé MM, Brand EC, Delemarre EM, Drylewicz J, Nierkens S, Verheijden RJ, Oldenburg B, Vercoulen Y, Suijkerbuijk KPM, van Wijk F
iScience 2023 Oct 20;26(10):107891
iScience 2023 Oct 20;26(10):107891
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Cao J, Gu H, Zhang X, Yun H, Li J, Si CY, Zhang J, Wang H
Virus research 2023 Oct 2;335:199201
Virus research 2023 Oct 2;335:199201
Mediation of endoplasmic reticulum stress and NF-κB signaling pathway in DINP-exacerbated allergic asthma: A toxicological study with Balb/c mice.
Lei F, Wu Y, Li C, Yan B, Chen S, Peng Q, Yang X, Ma P
Journal of hazardous materials 2023 Oct 15;460:132392
Journal of hazardous materials 2023 Oct 15;460:132392
Liraglutide intervention improves high-glucose-induced reactive gliosis of Müller cells and ECM dysregulation.
Shan Y, Gao X, Zhao K, Xu C, Li H, Hu Y, Lin W, Ma X, Xu Q, Kuang H, Hao M
Molecular and cellular endocrinology 2023 Oct 1;576:112013
Molecular and cellular endocrinology 2023 Oct 1;576:112013
Paneth cells protect intestinal stem cell niche to alleviate deoxynivalenol-induced intestinal injury.
Cui C, Wang X, Zheng Y, Li L, Wang F, Wei H, Peng J
Ecotoxicology and environmental safety 2023 Oct 1;264:115457
Ecotoxicology and environmental safety 2023 Oct 1;264:115457
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Wu X, Gao Y, Shi C, Tong J, Ma D, Shen J, Yang J, Ji M
Neuropharmacology 2023 Oct 1;237:109646
Neuropharmacology 2023 Oct 1;237:109646
Exploring the therapeutic potential of a nano micelle containing a carbon monoxide-releasing molecule for metabolic-associated fatty liver disease by modulating hypoxia-inducible factor-1α.
Cui Y, Guo C, Xia Z, Xue Y, Song B, Hu W, He X, Liang S, Wei Y, Zhang C, Wang H, Xu D, Zhang S, Fang J
Acta biomaterialia 2023 Oct 1;169:500-516
Acta biomaterialia 2023 Oct 1;169:500-516
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Huang W, Zhang Y, Zheng B, Ling X, Wang G, Li L, Wang W, Pan M, Li X, Meng Y
International immunopharmacology 2023 Nov;124(Pt B):111017
International immunopharmacology 2023 Nov;124(Pt B):111017
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.
Miao X, Ye H, Cui X, Guo X, Su F
Nutrition research (New York, N.Y.) 2023 Nov;119:119-131
Nutrition research (New York, N.Y.) 2023 Nov;119:119-131
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Jiang J, Zou Y, Xie C, Yang M, Tong Q, Yuan M, Pei X, Deng S, Tian M, Xiao L, Gong Y
Brain, behavior, and immunity 2023 Nov;114:195-213
Brain, behavior, and immunity 2023 Nov;114:195-213
Sleep deprivation alleviates depression-like behaviors in mice via inhibiting immune and inflammatory pathways and improving neuroplasticity.
Shi S, Zhang M, Xie W, Ju P, Chen N, Wang F, Lyu D, Wang M, Hong W
Journal of affective disorders 2023 Nov 1;340:100-112
Journal of affective disorders 2023 Nov 1;340:100-112
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Polymeric nano-micelle of carbon monoxide donor SMA/CORM2 ameliorates acetaminophen-induced liver injury via suppressing HMGB1/TLR4 signaling pathway.
Xue Y, Zhang D, Wei Y, Guo C, Song B, Cui Y, Zhang C, Xu D, Zhang S, Fang J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 May 1;184:106413
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 May 1;184:106413
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
Cao ZR, Zheng WX, Jiang YX, Chai H, Gong JH, Zhao MJ, Yan P, Liu YY, Liu XY, Huang ZT, Yang H, Peng DD, Zong KZ, Wu ZJ
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
Xie Z, Wu X, Cheng R, Huang J, Wang X, Shi Q, Xu B, Paulus YM, Yuan S, Liu Q
Experimental eye research 2023 Mar;228:109388
Experimental eye research 2023 Mar;228:109388
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Yao B, Cai Y, Wang W, Deng J, Zhao L, Han Z, Wan L
Orthopaedic surgery 2023 Mar;15(3):858-867
Orthopaedic surgery 2023 Mar;15(3):858-867
Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression.
Wang Y, Zheng G, Xie X, Yu W, Wang J, Zang F, Yang C, Xiao Q, Zhang R, Wei L, Wu X, Liang L, Cao P, Xu C, Li J, Hu B, Zhang T, Wu J, Chen H
Journal of nanobiotechnology 2023 Mar 3;21(1):76
Journal of nanobiotechnology 2023 Mar 3;21(1):76
Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury.
Wu N, Luo Q, Huang Y, Wan L, Hou X, Jiang Z, Li Y, Qiu J, Chen P, Yu K, Zhuang J, Yang Y
Investigative ophthalmology & visual science 2023 Mar 1;64(3):35
Investigative ophthalmology & visual science 2023 Mar 1;64(3):35
Enoxaparin sodium bone cement displays local anti-inflammatory effects by regulating the expression of IL-6 and TNF-α.
Hao K, Sang L, Ding L, Shen X, Fu D, Qi X
Heliyon 2023 Jun;9(6):e16530
Heliyon 2023 Jun;9(6):e16530
Investigation of macrophage polarization in herniated nucleus pulposus of patients with lumbar intervertebral disc herniation.
Li XC, Luo SJ, Wu F, Mu QC, Yang JH, Jiang C, Wang W, Zhou TL, Qin TD, Tan RX, Jian-Li, Huang CM, Wang MS, Bai XC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1335-1347
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1335-1347
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Li C, Sun F, Tian J, Li J, Sun H, Zhang Y, Guo S, Lin Y, Sun X, Zhao Y
Bioactive materials 2023 Jun;24:361-375
Bioactive materials 2023 Jun;24:361-375
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease.
Wang HL, Cheng YC, Yeh TH, Liu HF, Weng YH, Chen RS, Chen YC, Lu JC, Hwang TL, Wei KC, Liu YC, Wang YT, Hsu CC, Chiu TJ, Chiu CC
Biochemical pharmacology 2023 Jun;212:115524
Biochemical pharmacology 2023 Jun;212:115524
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q
FEBS open bio 2023 Jun;13(6):1107-1124
FEBS open bio 2023 Jun;13(6):1107-1124
Thymopentin (TP-5) prevents lipopolysaccharide-induced neuroinflammation and dopaminergic neuron injury by inhibiting the NF-κB/NLRP3 signaling pathway.
Peng SJ, Feng Y, Li X, Wang XX, Wang Y, Zhou BT, Liu Y, Liu T, Wu YC
International immunopharmacology 2023 Jun;119:110109
International immunopharmacology 2023 Jun;119:110109
A systematic pharmacology-based in vivo study to reveal the effective mechanism of Yupingfeng in asthma treatment.
Liu X, Yu Y, Wu Y, Luo A, Yang M, Li T, Li T, Mao B, Chen X, Fu J, Jiang H, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154783
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154783
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Ye S, Huang H, Xiao Y, Han X, Shi F, Luo W, Chen J, Ye Y, Zhao X, Huang W, Wang Y, Lai D, Liang G, Fu G
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Protocol for preparation of a photo-triggering double cross-linked adhesive, antibacterial, and biocompatible hydrogel for wound healing.
Zhai X, Hu M, Hu H, Yao X, Wei W
STAR protocols 2023 Jun 16;4(2):102315
STAR protocols 2023 Jun 16;4(2):102315
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Wu H, Wu Z, Qiu Y, Zhao F, Liao M, Zhong Z, Chen J, Zeng Y, Liu R
iScience 2023 Jun 16;26(6):106979
iScience 2023 Jun 16;26(6):106979
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Li XC, Wang S, Yang XX, Li TJ, Gu JX, Zhao L, Bao YR, Meng XS
Journal of ethnopharmacology 2023 Jun 12;309:116264
Journal of ethnopharmacology 2023 Jun 12;309:116264
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Cao X, Mao K, Zhang Y, Yang M, Liu H, Wang X, Hao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
TFP5 attenuates cyclin-dependent kinase 5-mediated islet β-cell damage in diabetes.
Liu S, Li B, Ma D, Tao Y, Song J, Bao L, Zhang G, Luo H, Cao S, E J, Zheng Y
Chemical biology & drug design 2023 Jul;102(1):76-87
Chemical biology & drug design 2023 Jul;102(1):76-87
Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries.
Zhou W, Wang C, Zhang B, Gou S
European journal of pharmacology 2023 Jul 5;950:175751
European journal of pharmacology 2023 Jul 5;950:175751
Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms.
Jia N, Gao Y, Li M, Liang Y, Li Y, Lin Y, Huang S, Lin Q, Sun X, He Q, Yao Y, Zhang B, Zhang Z, Zhang L
Signal transduction and targeted therapy 2023 Jul 28;8(1):280
Signal transduction and targeted therapy 2023 Jul 28;8(1):280
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Pulsatilla chinensis saponins ameliorated murine depression by inhibiting intestinal inflammation mediated IDO1 overexpression and rebalancing tryptophan metabolism.
Wang T, Song Y, Ai Z, Liu Y, Li H, Xu W, Chen L, Zhu G, Yang M, Su D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154852
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154852
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.
Liu X, Zhuang Y, Huang W, Wu Z, Chen Y, Shan Q, Zhang Y, Wu Z, Ding X, Qiu Z, Cui W, Wang Z
Nature communications 2023 Jul 11;14(1):4106
Nature communications 2023 Jul 11;14(1):4106
Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.
Wang MX, Luo W, Ye L, Jin LM, Yang B, Zhang QH, Qian JC, Wang Y, Zhang Y, Liang G
Acta pharmacologica Sinica 2023 Jan;44(1):120-132
Acta pharmacologica Sinica 2023 Jan;44(1):120-132
Inflammatory mechanisms of Ginkgo Biloba extract in improving memory functions through lncRNA-COX2/NF-κB pathway in mice with status epilepticus.
Zou X, Liu S, Zou H, Zhou W, Fu H, Wei J, Zhang J, Zeng H, Tan T, Zhou W, Wu H, Chen X, Zhou X
CNS neuroscience & therapeutics 2023 Jan;29(1):471-482
CNS neuroscience & therapeutics 2023 Jan;29(1):471-482
Early brainstem hemorrhage progression: multi-sequence magnetic resonance imaging and histopathology.
Guo X, Xu JK, Qi X, Wei Y, Wang CW, Li H, Ma L, You C, Tian M
Neural regeneration research 2023 Jan;18(1):170-175
Neural regeneration research 2023 Jan;18(1):170-175
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
Zhuang K, Tang H, Guo H, Yuan S
Microbial pathogenesis 2023 Jan;174:105937
Microbial pathogenesis 2023 Jan;174:105937
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L
Kidney international 2023 Jan;103(1):115-133
Kidney international 2023 Jan;103(1):115-133
Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage.
Bao S, Chen Z, Qin D, Xu H, Deng X, Zhang R, Ma J, Lu Z, Jiang S, Zhang X
Human reproduction (Oxford, England) 2023 Jan 5;38(1):57-74
Human reproduction (Oxford, England) 2023 Jan 5;38(1):57-74
Low-Dose Sodium Salicylate Promotes Ovulation by Regulating Steroids via CYP17A1.
Li T, Ren X, Li T, Yu L, Teng M, Zheng Y, Lei A
International journal of molecular sciences 2023 Jan 30;24(3)
International journal of molecular sciences 2023 Jan 30;24(3)
Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation.
Li X, Xie W, Pan Q, Zhang X, Zhang L, Zhao N, Xie Q, Ding J, Chai J
Cell communication and signaling : CCS 2023 Jan 30;21(1):24
Cell communication and signaling : CCS 2023 Jan 30;21(1):24
Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging.
Liang Z, Gong X, Ye R, Zhao Y, Yu J, Zhao Y, Bao J
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Identification of Senescent Cells in Peri-Implantitis and Prevention of Mini-Implant Loss Using Senolytics.
Yang N, Nakagawa M, Nishiura A, Yamada M, Morikuni H, Honda Y, Matsumoto N
International journal of molecular sciences 2023 Jan 28;24(3)
International journal of molecular sciences 2023 Jan 28;24(3)
Protein kinase D1 promotes the survival of random-pattern skin flaps in rats.
Chen J, Chen H, Muhammad I, Han T, Zhang D, Li B, Zhou X, Zhou F
Biochemical and biophysical research communications 2023 Jan 22;641:67-76
Biochemical and biophysical research communications 2023 Jan 22;641:67-76
Osteopontin associates with brain T(RM)-cell transcriptome and compartmentalization in donors with and without multiple sclerosis.
Hsiao CC, Engelenburg HJ, Jongejan A, Zhu J, Zhang B, Mingueneau M, Moerland PD, Huitinga I, Smolders J, Hamann J
iScience 2023 Jan 20;26(1):105785
iScience 2023 Jan 20;26(1):105785
IRF5 knockdown reverses TDP-related phenotypes partially by increasing TBK1 expression.
Li Y, Yu L, Liu C, Duan W, Zhang S, Li Z, Yi L, Guo M, Bi Y, Li C, Liu Y
Brain research 2023 Jan 1;1798:148155
Brain research 2023 Jan 1;1798:148155
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Yan M, Jin H, Pan C, Han X
Molecular neurobiology 2023 Feb;60(2):884-900
Molecular neurobiology 2023 Feb;60(2):884-900
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
Yang DG, Gao YY, Yin ZQ, Wang XR, Meng XS, Zou TF, Duan YJ, Chen YL, Liao CZ, Xie ZL, Fan XD, Sun L, Han JH, Yang XX
Acta pharmacologica Sinica 2023 Feb;44(2):308-320
Acta pharmacologica Sinica 2023 Feb;44(2):308-320
The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease.
Enoki Y, Nagai T, Hamamura Y, Osa S, Nakamura H, Taguchi K, Watanabe H, Maruyama T, Matsumoto K
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):553-564
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):553-564
Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy.
Xu C, Jiang Y, Wang H, Zhang Y, Ye Y, Qin H, Gao J, Dan Q, Du L, Liu L, Peng F, Li Y, Tu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204881
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204881
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Hu W, Yang J, Xue J, Ma J, Wu S, Wang J, Xu R, Wei J, Wang Y, Wang S, Liu X
Biomedicines 2023 Feb 5;11(2)
Biomedicines 2023 Feb 5;11(2)
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Gu G, Zhu B, Ren J, Song X, Fan B, Ding H, Shang J, Wu H, Li J, Wang H, Li J, Wei Z, Feng S
Cell & bioscience 2023 Feb 4;13(1):23
Cell & bioscience 2023 Feb 4;13(1):23
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Yuan G, Xiao L, Xie Y, Si L, Xu H, Xu W, Wang G
Neuroscience letters 2023 Feb 28;798:137058
Neuroscience letters 2023 Feb 28;798:137058
TNFR2 is a potent prognostic biomarker for post-transplant lung metastasis in patients with hepatocellular carcinoma.
Li H, Lin Z, Zhuo J, Yang M, Shen W, Hu Z, Ding Y, Chen H, He C, Yang X, Dong S, Wei X, Sun B, Zheng S, Lang R, Lu D, Xu X
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2023 Feb 28;35(1):66-80
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2023 Feb 28;35(1):66-80
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Wu J, Lin S, Chen W, Lian G, Wu W, Chen A, Sagor MIH, Luo L, Wang H, Xie L
Cell death discovery 2023 Feb 24;9(1):76
Cell death discovery 2023 Feb 24;9(1):76
Peroxiredoxins and Hypoxia-Inducible Factor-1α in Duodenal Tissue: Emerging Factors in the Pathophysiology of Pediatric Celiac Disease Patients.
Köse FA, Pabuccuoglu A, Karakoyun M, Aydogdu S
Current issues in molecular biology 2023 Feb 20;45(2):1779-1793
Current issues in molecular biology 2023 Feb 20;45(2):1779-1793
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
Ma Y, Deng Y, Li N, Dong A, Li H, Chen S, Zhang S, Zhang M
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
LncRNA GAS5 downregulates NLRP3 inflammasome activation-mediated pyroptosis in sepsis-induced myocardial injury by targeting SIRT3/AMPKα.
Luo M, Peng Y, Lv D, Xue Y, Huang L, Hu Y, Zhu W, Luo S, Shen J, Li X
Heliyon 2023 Dec;9(12):e22939
Heliyon 2023 Dec;9(12):e22939
Thyroid-stimulating hormone may participate in insulin resistance by activating toll-like receptor 4 in liver tissues of subclinical hypothyroid rats.
Bao S, Li F, Duan L, Li J, Jiang X
Molecular biology reports 2023 Dec;50(12):10637-10650
Molecular biology reports 2023 Dec;50(12):10637-10650
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
Yang Y, Hu Q, Kang H, Li J, Zhao X, Zhu L, Tang W, Wan M
MedComm 2023 Dec;4(6):e459
MedComm 2023 Dec;4(6):e459
RNA sequencing reveals the mechanism of FTO in inhibiting inflammation and excessive proliferation of lipopolysaccharide-induced human glomerular mesangial cells.
Zhuang X, Liu T, Wei L, Gao Y, Gao J
Naunyn-Schmiedeberg's archives of pharmacology 2023 Dec;396(12):3835-3846
Naunyn-Schmiedeberg's archives of pharmacology 2023 Dec;396(12):3835-3846
Hydroxypropyl-β-cyclodextrin inhibits the development of triple negative breast cancer by enhancing antitumor immunity.
Zhu M, Zhao Q, Zhang W, Xu H, Zhang B, Zhang S, Duan Y, Liao C, Yang X, Chen Y
International immunopharmacology 2023 Dec;125(Pt A):111168
International immunopharmacology 2023 Dec;125(Pt A):111168
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Yang Z, Ning R, Liu Q, Zang R, Liu S, Sun S
Physiological reports 2023 Dec;11(23):e15879
Physiological reports 2023 Dec;11(23):e15879
Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma.
Jie XL, Luo ZR, Yu J, Tong ZR, Li QQ, Wu JH, Tao Y, Feng PS, Lan JP, Wang P
Journal of ethnopharmacology 2023 Dec 5;317:116719
Journal of ethnopharmacology 2023 Dec 5;317:116719
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
Lin X, Fu T, Lei Y, Xu J, Wang S, He F, Xie Z, Zhang L
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264.7 macrophages.
Zhao Q, Zheng W, Yuan Z, Wang X, Huang A
Food chemistry 2023 Dec 15;429:136804
Food chemistry 2023 Dec 15;429:136804
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
Niu X, Meng Y, Cui J, Li R, Ding X, Niu B, Chang G, Xu N, Li G, Wang Y, Wang L
ACS nano 2023 Dec 12;17(23):23608-23625
ACS nano 2023 Dec 12;17(23):23608-23625
CD44 Drives M1 Macrophage Polarization in Diabetic Retinopathy.
Pan Z, Zhao Y, Zhou S, Wang J, Fan F
Current eye research 2023 Aug;48(8):770-780
Current eye research 2023 Aug;48(8):770-780
Ginsenoside Rb1 inhibits ferroptosis to ameliorate hypoxic-ischemic brain damage in neonatal rats.
Zhang M, Lin W, Tao X, Zhou W, Liu Z, Zhang Z, Jin S, Zhang H, Teng C, Zhu J, Guo X, Lin Z
International immunopharmacology 2023 Aug;121:110503
International immunopharmacology 2023 Aug;121:110503
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
Zhao T, Zhang Y, Liu L, Deng X, Guo J, Cao S, Zhu D, Xu J, Nikolaevna UV, Maratbek S, Wang Z, Sun Z, Gu X, Zhang H
ACS omega 2023 Aug 8;8(31):28797-28812
ACS omega 2023 Aug 8;8(31):28797-28812
Biocompatibility and efficacy of prostatic urethral lift in benign prostate hyperplasia: an in vivo and in vitro study.
Xia Y, Yuan T, Zou W, Li H, Ning J, Ruan Y, Xu L, Yu W, Cheng F
Scientific reports 2023 Aug 24;13(1):13828
Scientific reports 2023 Aug 24;13(1):13828
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Zhang F, Ke C, Zhou Z, Xu K, Wang Y, Liu Y, Tu J
Planta medica 2023 Apr;89(5):493-507
Planta medica 2023 Apr;89(5):493-507
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Xie Z, Wu XJ, Cheng RW, Cui JH, Yuan ST, Zhou JW, Liu QH
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
Wo B, Du C, Yang Y, Qi H, Liang Z, He C, Yao F, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway.
Wang M, Zhang F, Zhou J, Gong K, Chen S, Zhu X, Zhang M, Duan Y, Liao C, Han J, Yin Z
Nutrients 2023 Apr 30;15(9)
Nutrients 2023 Apr 30;15(9)
Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus.
Jin T, Fu X, Liu M, An F
Diabetology & metabolic syndrome 2023 Apr 29;15(1):87
Diabetology & metabolic syndrome 2023 Apr 29;15(1):87
Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis.
Sun Z, Lou Y, Hu X, Song F, Zheng X, Hu Y, Ding H, Zhang Y, Huang P
BMC pulmonary medicine 2023 Apr 28;23(1):149
BMC pulmonary medicine 2023 Apr 28;23(1):149
SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction.
Nie Y, Mou L, Long Q, Deng D, Hu R, Cheng J, Wu J
Virus research 2023 Apr 15;328:199086
Virus research 2023 Apr 15;328:199086
Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol.
Guo R, Zhu J, Chen L, Li J, Ding Q, Han Q, Zheng W, Li S
Frontiers in nutrition 2022;9:1026740
Frontiers in nutrition 2022;9:1026740
Blood serum analysis: A modified sandwich enzyme-linked immunosorbent assay protocol.
Cai D, Fraunfelder M, Chen SY
MethodsX 2022;9:101923
MethodsX 2022;9:101923
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197
The American journal of Chinese medicine 2022;50(8):2185-2197
Coprophagy Prevention Affects the Reproductive Performance in New Zealand White Rabbits Is Mediated through Nox4-ROS-NFκB Pathway.
Li Z, Li R, Li J, Wang Z, He H, Yan D, Yu L, Li H, Li M, Xu H
Oxidative medicine and cellular longevity 2022;2022:8999899
Oxidative medicine and cellular longevity 2022;2022:8999899
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Yu Q, Lin J, Ma Q, Li Y, Wang Q, Chen H, Liu Y, Liu B
Journal of diabetes research 2022;2022:8679548
Journal of diabetes research 2022;2022:8679548
Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.
Wang Y, Lin S, Chen Z, Chen Q, Fu M
Disease markers 2022;2022:8287192
Disease markers 2022;2022:8287192
Metformin Improves the Prognosis of Adult Mice with Sepsis-Associated Encephalopathy Better than That of Aged Mice.
Song G, Liang H, Song H, Ding X, Wang D, Zhang X, Sun T
Journal of immunology research 2022;2022:3218452
Journal of immunology research 2022;2022:3218452
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Ling J, Wu Y, Zou X, Chang Y, Li G, Fang M
Oxidative medicine and cellular longevity 2022;2022:2657713
Oxidative medicine and cellular longevity 2022;2022:2657713
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation.
Yu H, Zhang Z, Wei F, Hou G, You Y, Wang X, Cao S, Yang X, Liu W, Zhang S, Hu F, Zhang X
Oxidative medicine and cellular longevity 2022;2022:2240894
Oxidative medicine and cellular longevity 2022;2022:2240894
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis.
Zhang P, Wang Y, Yang W, Yin Y, Li C, Ma X, Shi L, Li R, Tao K
International journal of biological sciences 2022;18(16):6189-6209
International journal of biological sciences 2022;18(16):6189-6209
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Guo H, Zhang W, Wang Z, Li Z, Zhou J, Yang Z
Frontiers in molecular neuroscience 2022;15:977941
Frontiers in molecular neuroscience 2022;15:977941
Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.
Ding J, Shen L, Ye Y, Hu S, Ren Z, Liu T, Dai J, Li Z, Wang J, Luo Y, Zhang Q, Zhang X, Qi X, Huang J
Frontiers in molecular neuroscience 2022;15:861340
Frontiers in molecular neuroscience 2022;15:861340
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
Zhao WJ, Fan YP, Ou GY, Qiao XY
Journal of Cancer 2022;13(7):2281-2292
Journal of Cancer 2022;13(7):2281-2292
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Liu M, Peng Y, Che Y, Zhou M, Bai Y, Tang W, Huang S, Zhang B, Deng S, Wang C, Yu Z
Frontiers in pharmacology 2022;13:978587
Frontiers in pharmacology 2022;13:978587
Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation.
Han X, Li B, Bao J, Wu Z, Chen C, Ni J, Shen J, Song P, Peng Q, Wan R, Wang X, Wu J, Hu G
Frontiers in immunology 2022;13:968639
Frontiers in immunology 2022;13:968639
Roxadustat, a Hypoxia-Inducible Factor 1α Activator, Attenuates Both Long- and Short-Term Alcohol-Induced Alcoholic Liver Disease.
Gao Y, Jiang X, Yang D, Guo W, Wang D, Gong K, Peng Y, Jiang H, Shi C, Duan Y, Chen Y, Han J, Yang X
Frontiers in pharmacology 2022;13:895710
Frontiers in pharmacology 2022;13:895710
Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration in a Spontaneous Polygenic Model of Inherited Retinal Dystrophy.
Hollingsworth TJ, Wang X, White WA, Simpson RN, Jablonski MM
Frontiers in pharmacology 2022;13:839424
Frontiers in pharmacology 2022;13:839424
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
Zhang WH, Jin ZY, Yang ZH, Zhang JY, Ma XH, Guan J, Sun BL, Chen X
Frontiers in microbiology 2022;13:818111
Frontiers in microbiology 2022;13:818111
Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of Action.
Wang N, Chu F, Fei C, Pan L, Wang Y, Chen W, Peng D, Duan X, He L
Frontiers in pharmacology 2022;13:809505
Frontiers in pharmacology 2022;13:809505
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination.
Yuan G, Yang S, Yang S
Genes & diseases 2022 Sep;9(5):1357-1367
Genes & diseases 2022 Sep;9(5):1357-1367
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
Liu Q, Huang L, Cui Z, Qiao B, Li F, Wang C
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Zhu H, Zhang L, Jia H, Xu L, Cao Y, Zhai M, Li K, Xia L, Jiang L, Li X, Zhou Y, Liu J, Yu S, Duan W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154283
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154283
β-Lapachone, an NQO1 activator, alleviates diabetic cardiomyopathy by regulating antioxidant ability and mitochondrial function.
Wu PY, Lai SY, Su YT, Yang KC, Chau YP, Don MJ, Lu KH, Shy HT, Lai SM, Kung HN
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154255
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154255
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Zhao Y, Zhang T, Shen X, Huang A, Li H, Wang L, Liu X, Wang X, Song X, Wang S, Dong J, Shao N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
The role of proteoglycan form of DMP1 in cranial repair.
Liu Y, Niu P, Zhou M, Xue H
BMC molecular and cell biology 2022 Sep 30;23(1):43
BMC molecular and cell biology 2022 Sep 30;23(1):43
Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes.
Zhang Y, Yin K, Wang D, Wang Y, Lu H, Zhao H, Xing M
The Science of the total environment 2022 Sep 20;840:156727
The Science of the total environment 2022 Sep 20;840:156727
Synergistic anti-inflammatory effects of peimine, peiminine, and forsythoside a combination on LPS-induced acute lung injury by inhibition of the IL-17-NF-κB/MAPK pathway activation.
Liu C, Zhen D, Du H, Gong G, Wu Y, Ma Q, Quan ZS
Journal of ethnopharmacology 2022 Sep 15;295:115343
Journal of ethnopharmacology 2022 Sep 15;295:115343
Biomechanically-Adapted Immunohydrogels Reconstructing Myelin Sheath for Peripheral Nerve Regeneration.
Wang Y, Yan Z, Liu W, Liu C, Xu N, Wu Y, Sun F, Wang X, Qian Y, Jiang L, Sun X
Advanced healthcare materials 2022 Oct;11(20):e2201596
Advanced healthcare materials 2022 Oct;11(20):e2201596
Transcriptomic Analysis Reveals Lactobacillus reuteri Alleviating Alcohol-Induced Liver Injury in Mice by Enhancing the Farnesoid X Receptor Signaling Pathway.
Cheng Y, Xiang X, Liu C, Cai T, Li T, Chen Y, Bai J, Shi H, Zheng T, Huang M, Fu W
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12550-12564
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12550-12564
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Zhou W, Wang C, Liu Z, Gou S
Journal of medicinal chemistry 2022 Oct 13;65(19):13436-13451
Journal of medicinal chemistry 2022 Oct 13;65(19):13436-13451
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Zhang YW, Cao MM, Li YJ, Lu PP, Dai GC, Zhang M, Wang H, Rui YF
Journal of orthopaedic translation 2022 Nov;37:46-60
Journal of orthopaedic translation 2022 Nov;37:46-60
Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice.
Chen M, Xiao Y, Zhang F, Du J, Zhang L, Li Y, Lu D, Wang Z, Wu B
Biochemical pharmacology 2022 Nov;205:115286
Biochemical pharmacology 2022 Nov;205:115286
Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling.
Gao J, Yao M, Zhang W, Yang B, Yuan G, Liu JX, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113479
miR-146a-5p promotes epithelium regeneration against LPS-induced inflammatory injury via targeting TAB1/TAK1/NF-κB signaling pathway.
Chen X, Li W, Chen T, Ren X, Zhu J, Hu F, Luo J, Xing L, Zhou H, Sun J, Jiang Q, Zhang Y, Xi Q
International journal of biological macromolecules 2022 Nov 30;221:1031-1040
International journal of biological macromolecules 2022 Nov 30;221:1031-1040
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Zhang X, Liang P, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Peng B, Liu W, Yin J, Han S, He X
International journal of molecular sciences 2022 Nov 24;23(23)
International journal of molecular sciences 2022 Nov 24;23(23)
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.
Chen L, Li Y, Zeng S, Duan S, Huang Z, Liang Y
In vitro cellular & developmental biology. Animal 2022 May;58(5):408-418
In vitro cellular & developmental biology. Animal 2022 May;58(5):408-418
Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition.
Cao Y, Li Y, Fu SC, Shen J, Zhang H, Jiang C, Shu-Hang Yung P
Journal of orthopaedic translation 2022 May;34:102-112
Journal of orthopaedic translation 2022 May;34:102-112
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
Xia Z, Zhang C, Guo C, Song B, Hu W, Cui Y, Xue Y, Xia M, Xu D, Zhang S, Fang J
Acta biomaterialia 2022 May;144:42-53
Acta biomaterialia 2022 May;144:42-53
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737
Bioorganic chemistry 2022 May;122:105737
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Desmethylbellidifolin Attenuates Dextran Sulfate Sodium-Induced Colitis: Impact on Intestinal Barrier, Intestinal Inflammation and Gut Microbiota.
Wu J, Wu Y, Chen Y, Liu M, Yu H, Zhang Y, Wang T
Planta medica 2022 Jun;88(7):559-569
Planta medica 2022 Jun;88(7):559-569
Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.
Du J, Wang P, Gou Q, Jin S, Xue H, Li D, Tian D, Sun J, Zhang X, Teng X, Wu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113018
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113018
MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice.
Wu G, Zhang D, Yang L, Wu Q, Yuan L
Molecular immunology 2022 Jun;146:57-68
Molecular immunology 2022 Jun;146:57-68
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice.
Nguyen N, Xu S, Lam TYW, Liao W, Wong WSF, Ge R
Molecular medicine (Cambridge, Mass.) 2022 Jun 25;28(1):72
Molecular medicine (Cambridge, Mass.) 2022 Jun 25;28(1):72
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome.
Xiao N, Wang J, Wang T, Xiong X, Zhou J, Su X, Peng J, Yang C, Li X, Lin G, Lu G, Gong F, Cheng L
eLife 2022 Jun 24;11
eLife 2022 Jun 24;11
Poria cocos water-soluble polysaccharide modulates anxiety-like behavior induced by sleep deprivation by regulating the gut dysbiosis, metabolic disorders and TNF-α/NF-κB signaling pathway.
Zhang DD, Li HJ, Zhang HR, Ye XC
Food & function 2022 Jun 20;13(12):6648-6664
Food & function 2022 Jun 20;13(12):6648-6664
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Wang Y, Xie W, Feng Y, Xu Z, He Y, Xiong Y, Chen L, Li X, Liu J, Liu G, Wu Q
International journal of molecular medicine 2022 Jul;50(1)
International journal of molecular medicine 2022 Jul;50(1)
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
Yuan D, Lin L, Peng Y, Zhou Y, Li L, Xiao W, Gong Z
Journal of food biochemistry 2022 Jul;46(7):e14140
Journal of food biochemistry 2022 Jul;46(7):e14140
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
Li Y, Mao M, Zhu L, Sun Q, Tong J, Zhou Z
International immunopharmacology 2022 Jul;108:108898
International immunopharmacology 2022 Jul;108:108898
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Li T, Bai J, Du Y, Tan P, Zheng T, Chen Y, Cheng Y, Cai T, Huang M, Fu W, Wen J
International immunopharmacology 2022 Jul;108:108892
International immunopharmacology 2022 Jul;108:108892
Reduced inhibition underlies early life LPS exposure induced-cognitive impairment: Prevention by environmental enrichment.
Wu XM, Ji MH, Yin XY, Gu HW, Zhu TT, Wang RZ, Yang JJ, Shen JC
International immunopharmacology 2022 Jul;108:108724
International immunopharmacology 2022 Jul;108:108724
A photo-triggering double cross-linked adhesive, antibacterial, and biocompatible hydrogel for wound healing.
Hu H, Zhai X, Li W, Ji S, Dong W, Chen W, Wei W, Lu Z
iScience 2022 Jul 15;25(7):104619
iScience 2022 Jul 15;25(7):104619
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Xu B, Yang R, Yang B, Li L, Chen J, Fu J, Qu X, Huo D, Tan C, Chen H, Peng Z, Wang X
Molecular brain 2022 Jan 3;15(1):4
Molecular brain 2022 Jan 3;15(1):4
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
Huang X, Zha B, Zhang M, Li Y, Wu Y, Zhang R, Sheng L, Xu J, Yu Z, Gao C, Chen Z, Ding H, Ma L, Zhang Y, Zang S, Zhang TN, Liu J
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Phytotherapy research : PTR 2022 Feb;36(2):899-913
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Zhu J, Guo M, Cui Y, Meng Y, Ding J, Zeng W, Zhou W
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Yang L, Wu G, Wu Q, Peng L, Yuan L
Cell death discovery 2022 Feb 14;8(1):62
Cell death discovery 2022 Feb 14;8(1):62
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Yu J, Qi HL, Zhang H, Zhao ZY, Jing-Zhao, Nie ZY
Inflammation 2022 Dec;45(6):2406-2418
Inflammation 2022 Dec;45(6):2406-2418
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
Hui G, Yang LI, Lei F, Yujie X, Lizhong H, Dan M, Hui Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
Hadh deficiency induced oligoasthenoteratozoospermia through the TNF-α/Bcl-2 pathway in male mice.
Zhu H, Wang H, Cheng Y, Liu D, Zhang A, Wen Z, Gao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22661
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22661
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Wei C, Chen X, Chen D, He J, Zheng P, Chen H, Yan H, Yu B, Luo Y, Huang Z
Animal biotechnology 2022 Dec;33(7):1398-1406
Animal biotechnology 2022 Dec;33(7):1398-1406
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Guan G, Zhang Q, Jiang Z, Liu J, Wan J, Jin P, Lv Q
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice.
Olivares-González L, Velasco S, Gallego I, Esteban-Medina M, Puras G, Loucera C, Martínez-Romero A, Peña-Chilet M, Pedraz JL, Rodrigo R
Antioxidants (Basel, Switzerland) 2022 Dec 30;12(1)
Antioxidants (Basel, Switzerland) 2022 Dec 30;12(1)
In vitro and in vivo biological evaluation of newly synthesized multi-target 20(R)-panaxadiol derivatives for treating Alzheimer's disease.
Pang L, Li J, Liu Z, Quan YS, Sui HH, Jia Y, Chen F, Lee JJ, Liu P, Quan ZS, Shen QK, Guo HY
European journal of medicinal chemistry 2022 Dec 15;244:114825
European journal of medicinal chemistry 2022 Dec 15;244:114825
Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes.
Juin SK, Pushpakumar S, Tyagi SC, Sen U
Scientific reports 2022 Dec 15;12(1):21707
Scientific reports 2022 Dec 15;12(1):21707
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
Cui L, Wang Y, Ren L, Li Z, Jiang Y, Wang C, Liu X, Ren Y, Hu X
Parasites & vectors 2022 Dec 13;15(1):464
Parasites & vectors 2022 Dec 13;15(1):464
Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.
Pinto AP, da Rocha AL, Marafon BB, Nogueira JE, Branco LGS, Pauli JR, de Moura LP, Cintra DE, Ropelle ER, da Silva ASR
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):893-902
Clinical and experimental pharmacology & physiology 2022 Aug;49(8):893-902
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
Liang M, Wang Z, Li H, Liu B, Yang L
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23087
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23087
High triiodothyronine levels induce myocardial hypertrophy via BAFF overexpression.
Li GQ, Liu XM, Liu BL, Zhong Y, Gu QW, Miao JJ, Wang J, Liu S, Mao XM
Journal of cellular and molecular medicine 2022 Aug;26(16):4453-4462
Journal of cellular and molecular medicine 2022 Aug;26(16):4453-4462
Intestinal Klebsiella pneumoniae Contributes to Pneumonia by Synthesizing Glutamine in Multiple Myeloma.
Wang Y, Yang Q, Zhu Y, Jian X, Guo J, Zhang J, Kuang C, Feng X, An G, Qiu L, Li G, He Y, Zhou W
Cancers 2022 Aug 29;14(17)
Cancers 2022 Aug 29;14(17)
Vasoactive Effects of Chronic Treatment with Fructose and Slow-Releasing H(2)S Donor GYY-4137 in Spontaneously Hypertensive Rats: The Role of Nitroso and Sulfide Signalization.
Berenyiova A, Cebova M, Aydemir BG, Golas S, Majzunova M, Cacanyiova S
International journal of molecular sciences 2022 Aug 16;23(16)
International journal of molecular sciences 2022 Aug 16;23(16)
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Zhou S, Xue J, Shan J, Hong Y, Zhu W, Nie Z, Zhang Y, Ji N, Luo X, Zhang T, Ma W
Nutrients 2022 Aug 15;14(16)
Nutrients 2022 Aug 15;14(16)
Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis.
Qu L, Shi K, Xu J, Liu C, Ke C, Zhan X, Xu K, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153945
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153945
Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice.
Yan B, Xie D, Wu Y, Wang S, Zhang X, Zhao T, Liu L, Ma P, Li G, Yang Y, Zhao Y, Zheng T, Geng R, Li B, Zheng Q
Cell death discovery 2022 Apr 21;8(1):217
Cell death discovery 2022 Apr 21;8(1):217
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Li T, He X, Luo L, Zeng H, Ren S, Chen Y
Frontiers in cell and developmental biology 2021;9:599020
Frontiers in cell and developmental biology 2021;9:599020
Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.
Qian X, Zhang S, Duan L, Yang F, Zhang K, Yan F, Ge S
Journal of Alzheimer's disease : JAD 2021;79(4):1785-1800
Journal of Alzheimer's disease : JAD 2021;79(4):1785-1800
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.
Xu HL, Li SK, Xue XA, Chen ZY, Hua YH
BioMed research international 2021;2021:6641701
BioMed research international 2021;2021:6641701
Knockout of Bruton's tyrosine kinase in macrophages attenuates diabetic nephropathy in streptozotocin-induced mice.
Fan Z, Li Y, Xia L, Wu Y
American journal of translational research 2021;13(11):12352-12363
American journal of translational research 2021;13(11):12352-12363
Peroxisome Proliferator-Activated Receptor-Gamma Reduces ER Stress and Inflammation via Targeting NGBR Expression.
Ma J, Zeng P, Liu L, Zhu M, Zheng J, Wang C, Zhao X, Hu W, Yang X, Duan Y, Han J, Miao QR, Chen Y
Frontiers in pharmacology 2021;12:817784
Frontiers in pharmacology 2021;12:817784
Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid.
Li X, Jiang B, Zou Y, Zhang J, Fu YY, Zhai XY
Frontiers in pharmacology 2021;12:788977
Frontiers in pharmacology 2021;12:788977
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219
Frontiers in physiology 2021;12:744219
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells.
Yang R, Zhao Q, Rao J, Zeng F, Yuan S, Ji M, Sun X, Li J, Yang J, Cui J, Jin Z, Liu L, Liu Z
Frontiers in microbiology 2021;12:654709
Frontiers in microbiology 2021;12:654709
Ibudilast Attenuates Folic Acid-Induced Acute Kidney Injury by Blocking Pyroptosis Through TLR4-Mediated NF-κB and MAPK Signaling Pathways.
Li X, Zou Y, Fu YY, Xing J, Wang KY, Wan PZ, Wang M, Zhai XY
Frontiers in pharmacology 2021;12:650283
Frontiers in pharmacology 2021;12:650283
Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.
Li C, Sui C, Wang W, Yan J, Deng N, Du X, Cheng F, Ma X, Wang X, Wang Q
Frontiers in pharmacology 2021;12:599543
Frontiers in pharmacology 2021;12:599543
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.
Zhang B, Xu H, Chen J, Zhu X, Xue Y, Yang Y, Ao J, Hua Y, Ji M
Theranostics 2021;11(7):3074-3088
Theranostics 2021;11(7):3074-3088
Activation of the cGAS-STING signaling pathway in adenomyosis patients.
Lin Y, Wang L, Ye M, Yu KN, Sun X, Xue M, Deng X
Immunity, inflammation and disease 2021 Sep;9(3):932-942
Immunity, inflammation and disease 2021 Sep;9(3):932-942
The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation.
Liu D, Wei Y, Liu Y, Wu T, Hu J, Lu H
Molecular neurobiology 2021 Sep;58(9):4506-4519
Molecular neurobiology 2021 Sep;58(9):4506-4519
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Sheng S, Zou M, Yang Y, Guan M, Ren S, Wang X, Wang L, Xue Y
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Xian M, Cai J, Zheng K, Liu Q, Liu Y, Lin H, Liang S, Wang S
Food & function 2021 Sep 7;12(17):8056-8067
Food & function 2021 Sep 7;12(17):8056-8067
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Cheng J, Hao J, Jiang X, Ji J, Wu T, Chen X, Zhang F
International immunopharmacology 2021 Oct;99:108006
International immunopharmacology 2021 Oct;99:108006
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Kitayama K, Kawamoto T, Kawakami Y, Hara H, Takemori T, Fujiwara S, Yahiro S, Miyamoto T, Mifune Y, Hoshino Y, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Kuroda R, Akisue T
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
An experimental model of the epithelial to mesenchymal transition and pro-fibrogenesis in urothelial cells related to bladder pain syndrome/interstitial cystitis.
Jin XW, Wang QZ, Zhao Y, Liu BK, Zhang X, Wang XJ, Lu GL, Pan JW, Shao Y
Translational andrology and urology 2021 Nov;10(11):4120-4131
Translational andrology and urology 2021 Nov;10(11):4120-4131
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer.
Hashimoto A, Sarker D, Reebye V, Jarvis S, Sodergren MH, Kossenkov A, Sanseviero E, Raulf N, Vasara J, Andrikakou P, Meyer T, Huang KW, Plummer R, Chee CE, Spalding D, Pai M, Khan S, Pinato DJ, Sharma R, Basu B, Palmer D, Ma YT, Evans J, Habib R, Martirosyan A, Elasri N, Reynaud A, Rossi JJ, Cobbold M, Habib NA, Gabrilovich DI
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 1;27(21):5961-5978
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 1;27(21):5961-5978
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis.
Wang P, Cui Y, Ren Q, Yan B, Zhao Y, Yu P, Gao G, Shi H, Chang S, Chang YZ
Cell death & disease 2021 May 5;12(5):447
Cell death & disease 2021 May 5;12(5):447
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Zhong H, Zhou Z, Guo L, Liu F, Zheng B, Bi S, Tian C
Mechanisms of ageing and development 2021 Mar;194:111417
Mechanisms of ageing and development 2021 Mar;194:111417
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Xie Y, Liu B, Pan J, Liu J, Li X, Li H, Qiu S, Xiang X, Zheng P, Chen J, Yuan Y, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway.
Zhang W, Yu H, Lin Q, Liu X, Cheng Y, Deng B
Aging 2021 Mar 26;13(7):10659-10671
Aging 2021 Mar 26;13(7):10659-10671
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Zheng S, Cao P, Yin Z, Wang X, Chen Y, Yu M, Xu B, Liao C, Duan Y, Zhang S, Han J, Yang X
Food & function 2021 Mar 15;12(5):2323-2334
Food & function 2021 Mar 15;12(5):2323-2334
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
The effects of BMMSC treatment on lung tissue degeneration in elderly macaques.
Yang YK, Li Y, Wang YY, Ruan GP, Tian C, Wang Q, He HY, Zhu GH, Fang D, Wang M, Zhu XQ, Pan XH
Stem cell research & therapy 2021 Mar 1;12(1):156
Stem cell research & therapy 2021 Mar 1;12(1):156
Excessive downhill training leads to early onset of knee osteoarthritis.
Morais GP, Chemerka C, Masson A, Seerattan RA, da Rocha AL, Krawetz R, da Silva ASR, Herzog W
Osteoarthritis and cartilage 2021 Jun;29(6):870-881
Osteoarthritis and cartilage 2021 Jun;29(6):870-881
Polysaccharide MCP extracted from Morchella esculenta reduces atherosclerosis in LDLR-deficient mice.
Wang D, Yin Z, Ma L, Han L, Chen Y, Pan W, Gong K, Gao Y, Yang X, Chen Y, Han J, Duan Y
Food & function 2021 Jun 7;12(11):4842-4854
Food & function 2021 Jun 7;12(11):4842-4854
Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model.
Ko HM, Lee SH, Jee W, Jung JH, Kim KI, Jung HJ, Jang HJ
Pharmaceutics 2021 Jul 6;13(7)
Pharmaceutics 2021 Jul 6;13(7)
WITHDRAWN: Immunohistochemical study of inflammatory responses in septa arising from type I intestinal atresia.
Liu X, Hao P, Xie X, Li Y, Li S, Song Y, Feng C, Ye M, Wei Y, Zhao P, Li L, Jin ZW
Histology and histopathology 2021 Jul 27;:18364
Histology and histopathology 2021 Jul 27;:18364
Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the gut microbiota.
Zhu LQ, Zhang L, Zhang J, Chang GL, Liu G, Yu DD, Yu XM, Zhao MS, Ye B
Journal of integrative medicine 2021 Jan;19(1):56-65
Journal of integrative medicine 2021 Jan;19(1):56-65
Suppression of adenosine A(2a) receptors alleviates bladder overactivity and hyperalgesia in cyclophosphamide-induced cystitis by inhibiting TRPV1.
Yang Y, Zhang H, Lu Q, Liu X, Fan Y, Zhu J, Sun B, Zhao J, Dong X, Li L
Biochemical pharmacology 2021 Jan;183:114340
Biochemical pharmacology 2021 Jan;183:114340
Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in goat male germline stem cells.
Wei YD, Du XM, Yang DH, Ma FL, Yu XW, Zhang MF, Li N, Peng S, Liao MZ, Li GP, Bai CL, Liu WS, Hua JL
Zoological research 2021 Jan 18;42(1):14-27
Zoological research 2021 Jan 18;42(1):14-27
Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.
Cai GL, Yang ZX, Guo DY, Hu CB, Yan ML, Yan J
Scientific reports 2021 Feb 3;11(1):2918
Scientific reports 2021 Feb 3;11(1):2918
Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma.
Chen X, Cheng B, Dai D, Wu Y, Feng Z, Tong C, Wang X, Zhao J
Cell death discovery 2021 Feb 17;7(1):33
Cell death discovery 2021 Feb 17;7(1):33
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Guo S, Dong L, Li J, Chen Y, Yao Y, Zeng R, Shushakova N, Haller H, Xu G, Rong S
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation.
Yang HL, Li MM, Zhou MF, Xu HS, Huan F, Liu N, Gao R, Wang J, Zhang N, Jiang L
Inflammation 2021 Dec;44(6):2448-2462
Inflammation 2021 Dec;44(6):2448-2462
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Zhang Z, Zhou X, Liu J, Zheng Y, Wu Y, Yang W, Yi Y, Liu J, Wang J
Biochemical and biophysical research communications 2021 Dec 17;583:135-141
Biochemical and biophysical research communications 2021 Dec 17;583:135-141
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
Pan S, Zhang Y, Huang M, Deng Z, Zhang A, Pei L, Wang L, Zhao W, Ma L, Zhang Q, Cui D
Biomaterials 2021 Aug;275:120946
Biomaterials 2021 Aug;275:120946
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation.
Yang Z, Chen Z, Wang C, Huang P, Luo M, Zhou R
Cytokine 2021 Aug;144:155535
Cytokine 2021 Aug;144:155535
Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa.
Hollingsworth TJ, Hubbard MG, Levi HJ, White W, Wang X, Simpson R, Jablonski MM, Gross AK
Biomolecules 2021 Aug 6;11(8)
Biomolecules 2021 Aug 6;11(8)
Platelet membrane-camouflaged silver metal-organic framework drug system against infections caused by methicillin-resistant Staphylococcus aureus.
Huang R, Cai GQ, Li J, Li XS, Liu HT, Shang XL, Zhou JD, Nie XM, Gui R
Journal of nanobiotechnology 2021 Aug 4;19(1):229
Journal of nanobiotechnology 2021 Aug 4;19(1):229
Nr2e1 deficiency aggravates insulin resistance and chronic inflammation of visceral adipose tissues in a diet-induced obese mice model.
He G, Gu J, Wang H, Cheng S, Xiong Q, Ke M, Hu Y, Feng J, Song L, Liu Z, Xu Y
Life sciences 2021 Aug 1;278:119562
Life sciences 2021 Aug 1;278:119562
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638
British journal of pharmacology 2021 Apr;178(7):1620-1638
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Xiong H, Luo M, Ju Y, Zhao Z, Zhang M, Xu R, Ren Y, Yang G, Mei Z
Journal of ethnopharmacology 2021 Apr 6;269:113707
Journal of ethnopharmacology 2021 Apr 6;269:113707
Inhibition of Matrix Metalloproteinase with BB-94 Protects against Caerulein-Induced Pancreatitis via Modulating Neutrophil and Macrophage Activation.
Wu Z, Mulatibieke T, Niu M, Li B, Dai J, Ye X, He Y, Chen C, Wen L, Hu G
Gastroenterology research and practice 2020;2020:8903610
Gastroenterology research and practice 2020;2020:8903610
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
He M, Qian K, Zhang Y, Huang XF, Deng C, Zhang B, Gao G, Li J, Xie H, Sun T
Frontiers in neuroscience 2020;14:589650
Frontiers in neuroscience 2020;14:589650
Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma.
Fu W, Wang W, Li H, Jiao Y, Huo R, Yan Z, Wang J, Wang S, Wang J, Chen D, Cao Y, Zhao J
Frontiers in immunology 2020;11:835
Frontiers in immunology 2020;11:835
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
High Dimensional Mass Cytometry Analysis Reveals Characteristics of the Immunosuppressive Microenvironment in Diffuse Astrocytomas.
Fu W, Wang W, Li H, Jiao Y, Weng J, Huo R, Yan Z, Wang J, Xu H, Wang S, Wang J, Chen D, Cao Y, Zhao J
Frontiers in oncology 2020;10:78
Frontiers in oncology 2020;10:78
Ameliorating Effect of Pentadecapeptide Derived from Cyclina sinensis on Cyclophosphamide-Induced Nephrotoxicity.
Jiang X, Ren Z, Zhao B, Zhou S, Ying X, Tang Y
Marine drugs 2020 Sep 9;18(9)
Marine drugs 2020 Sep 9;18(9)
Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems.
Li GM, Liu LP, Yin B, Liu YY, Dong WW, Gong S, Zhang J, Tan JH
Poultry science 2020 Nov;99(11):6084-6093
Poultry science 2020 Nov;99(11):6084-6093
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex.
Zheng F, Ye C, Wan GW, Zhou B, Tong Y, Lei JZ, Chen Q, Li YH, Kang YM, Zhu GQ
Pflugers Archiv : European journal of physiology 2020 Nov;472(11):1577-1586
Pflugers Archiv : European journal of physiology 2020 Nov;472(11):1577-1586
Activated microglia-derived macrophage-like cells exacerbate brain edema after ischemic stroke correlate with astrocytic expression of aquaporin-4 and interleukin-1 alpha release.
Murata Y, Sugimoto K, Yang C, Harada K, Gono R, Harada T, Miyashita Y, Higashisaka K, Katada R, Tanaka J, Matsumoto H
Neurochemistry international 2020 Nov;140:104848
Neurochemistry international 2020 Nov;140:104848
BET Protein Inhibition Prolongs Cardiac Transplant Survival via Enhanced Myocardial Autophagy.
Chen J, Miao X, Liu C, Liu B, Wu X, Kong D, Sun Q, Gong W
Transplantation 2020 Nov;104(11):2317-2326
Transplantation 2020 Nov;104(11):2317-2326
Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose.
Wang Y, Cui X, Lin Q, Cai J, Tang L, Liang Y
Journal of agricultural and food chemistry 2020 Nov 4;68(44):12271-12283
Journal of agricultural and food chemistry 2020 Nov 4;68(44):12271-12283
Antiviral mechanism of carvacrol on HSV-2 infectivity through inhibition of RIP3-mediated programmed cell necrosis pathway and ubiquitin-proteasome system in BSC-1 cells.
Wang L, Wang D, Wu X, Xu R, Li Y
BMC infectious diseases 2020 Nov 11;20(1):832
BMC infectious diseases 2020 Nov 11;20(1):832
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, Bi J, Sun W, Huang T, Li L, Gong J, Li X, Hui Q, Wang X
BMJ open diabetes research & care 2020 May;8(1)
BMJ open diabetes research & care 2020 May;8(1)
BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats.
Lu L, Wu C, Lu BJ, Xie D, Wang Z, Bahaji Azami NL, An YT, Wang HJ, Ye G, Sun MY
Journal of ethnopharmacology 2020 Mar 1;249:112301
Journal of ethnopharmacology 2020 Mar 1;249:112301
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, Li Z, Cheng J, Guan S, Sun S, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Li J, Liu L, Zhao Q, Chen M
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Myeloid-specific dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage.
Han X, Ni J, Wu Z, Wu J, Li B, Ye X, Dai J, Chen C, Xue J, Wan R, Wen L, Wang X, Hu G
British journal of pharmacology 2020 Jul;177(13):2991-3008
British journal of pharmacology 2020 Jul;177(13):2991-3008
Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury.
Albashari A, He Y, Zhang Y, Ali J, Lin F, Zheng Z, Zhang K, Cao Y, Xu C, Luo L, Wang J, Ye Q
ACS omega 2020 Jul 7;5(26):16064-16075
ACS omega 2020 Jul 7;5(26):16064-16075
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, Sun S, Chu X, Cheng J, Guan S, Li Z, Chu L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts.
de Vicente LG, Pinto AP, Muñoz VR, Rovina RL, da Rocha AL, Gaspar RC, da Silva LECM, Simabuco FM, Frantz FG, Pauli JR, de Moura LP, Cintra DE, Ropelle ER, da Silva ASR
Life sciences 2020 Jan 1;240:117107
Life sciences 2020 Jan 1;240:117107
Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway.
Ni R, Song G, Fu X, Song R, Li L, Pu W, Gao J, Hu J, Liu Q, He F, Zhang D, Huang G
Biomaterials 2020 Feb;232:119730
Biomaterials 2020 Feb;232:119730
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Guo S, Zhang F, Chen Y, Chen Y, Shushakova N, Yao Y, Zeng R, Li J, Lu X, Chen R, Haller H, Gueler F, Xu G, Rong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
Polysaccharides from the Fleshy Fruits of Camellia oleifera Attenuate the Kidney Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Li J, Xie F, Zhu X, Hu H, Fang X, Huang Z, Liu Z, Wu S
Journal of medicinal food 2020 Dec;23(12):1275-1286
Journal of medicinal food 2020 Dec;23(12):1275-1286
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Zhao Z, Li J, Zheng B, Liang Y, Shi J, Zhang J, Han X, Chu L, Chu X, Gao Y
Molecular medicine reports 2020 Dec;22(6):5271-5281
Molecular medicine reports 2020 Dec;22(6):5271-5281
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, Wang Y, Yan W, Zhou Z, Yang H
Neurotoxicity research 2020 Apr;37(4):913-925
Neurotoxicity research 2020 Apr;37(4):913-925
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Jia J, Gong X, Zhao Y, Yang Z, Ji K, Luan T, Zang B, Li G
Frontiers in immunology 2019;10:1491
Frontiers in immunology 2019;10:1491
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Xu F, Hou B, Zhu X, Liu Y, Shi X, Li S, Li Z, Cai W, Zhou Y, Qiu L
Acta parasitologica 2019 Sep;64(3):520-527
Acta parasitologica 2019 Sep;64(3):520-527
Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response.
Wei X, Sun G, Zhao X, Wu Q, Chen L, Xu Y, Pang X, Qi G
International journal of molecular medicine 2019 Oct;44(4):1425-1435
International journal of molecular medicine 2019 Oct;44(4):1425-1435
Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice.
Xia H, Zhu X, Zhang X, Jiang H, Li B, Wang Z, Li D, Jin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109287
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109287
Osteocytic connexin 43 channels affect fracture healing.
Chen Y, Chen M, Xue T, Li G, Wang D, Shang P, Jiang JX, Xu H
Journal of cellular physiology 2019 Nov;234(11):19824-19832
Journal of cellular physiology 2019 Nov;234(11):19824-19832
miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN.
Zhang S, He K, Zhou W, Cao J, Jin Z
Molecular medicine reports 2019 May;19(5):4288-4296
Molecular medicine reports 2019 May;19(5):4288-4296
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, Zhang H, Bo T, Zhou X, Yu Y, Zhang H, Zhao M, Wang L, Yu C, Gao L, Jiang W, Zhang Q, Zhao J
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.
Zheng C, Wu SM, Lian H, Lin YZ, Zhuang R, Thapa S, Chen QZ, Chen YF, Lin JF
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, Shao M, Zou H
Transplant immunology 2019 Jun;54:20-28
Transplant immunology 2019 Jun;54:20-28
Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.
He M, Huang XF, Gao G, Zhou T, Li W, Hu J, Chen J, Li J, Sun T
Psychoneuroendocrinology 2019 Jun;104:286-299
Psychoneuroendocrinology 2019 Jun;104:286-299
Highly Acylated Anthocyanins from Purple Sweet Potato ( Ipomoea batatas L.) Alleviate Hyperuricemia and Kidney Inflammation in Hyperuricemic Mice: Possible Attenuation Effects on Allopurinol.
Zhang ZC, Zhou Q, Yang Y, Wang Y, Zhang JL
Journal of agricultural and food chemistry 2019 Jun 5;67(22):6202-6211
Journal of agricultural and food chemistry 2019 Jun 5;67(22):6202-6211
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191
ACS omega 2019 Jun 30;4(6):10185-10191
Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro.
Li M, Xu J, Mei X, Chi G, Li L, Song Y, He X, Li Y
Transplant immunology 2019 Feb;52:57-67
Transplant immunology 2019 Feb;52:57-67
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
Chen S, Zeng X, Zong W, Wang X, Chen L, Zhou L, Li C, Huang Q, Huang X, Zeng G, Hu K, Ouyang DS
Neurochemical research 2019 Feb;44(2):472-484
Neurochemical research 2019 Feb;44(2):472-484
Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin.
Ruan LY, Li MH, Xing YX, Hong W, Chen C, Chen JF, Xu H, Zhao WL, Wang JS
Journal of ethnopharmacology 2019 Feb 10;230:81-94
Journal of ethnopharmacology 2019 Feb 10;230:81-94
The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss.
Zhang G, Zheng H, Pyykko I, Zou J
Hearing research 2019 Aug;379:59-68
Hearing research 2019 Aug;379:59-68
IL-6 induced M1 type macrophage polarization increases radiosensitivity in HPV positive head and neck cancer.
Chen X, Fu E, Lou H, Mao X, Yan B, Tong F, Sun J, Wei L
Cancer letters 2019 Aug 1;456:69-79
Cancer letters 2019 Aug 1;456:69-79
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Zheng J, Fan R, Wu H, Yao H, Yan Y, Liu J, Ran L, Sun Z, Yi L, Dang L, Gan P, Zheng P, Yang T, Zhang Y, Tang T, Wang Y
Nature communications 2019 Apr 8;10(1):1604
Nature communications 2019 Apr 8;10(1):1604
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Guo HH, Feng CL, Zhang WX, Luo ZG, Zhang HJ, Zhang TT, Ma C, Zhan Y, Li R, Wu S, Abliz Z, Li C, Li XL, Ma XL, Wang LL, Zheng WS, Han YX, Jiang JD
Nature communications 2019 Apr 30;10(1):1981
Nature communications 2019 Apr 30;10(1):1981
The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice.
Yang Y, Liu X, Liu Y, Fu H, Gao Y, Liu X, Jiang X
Cell & bioscience 2018;8:20
Cell & bioscience 2018;8:20
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Luo D, Liu L, Liang FX, Yu ZM, Chen R
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, Lv Y, Liu Q, Guo C, Zhou Y
Drug design, development and therapy 2018;12:4067-4082
Drug design, development and therapy 2018;12:4067-4082
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Wang JT, Xie WQ, Liu FQ, Bi Y, Zhu XJ, Wang QE, Zheng YF
American journal of translational research 2018;10(6):1713-1721
American journal of translational research 2018;10(6):1713-1721
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Huang D, Chen J, Yang L, Ouyang Q, Li J, Lao L, Zhao J, Liu J, Lu Y, Xing Y, Chen F, Su F, Yao H, Liu Q, Su S, Song E
Nature immunology 2018 Oct;19(10):1112-1125
Nature immunology 2018 Oct;19(10):1112-1125
Gene transfer of a naked plasmid (pUDK-HGF) encoding human hepatocyte growth factor attenuates skin/muscle incision and retraction-induced chronic post-surgical pain in rats.
Hu C, Lu Y, Chen X, Wu Z, Zhang Q
European journal of pain (London, England) 2018 May;22(5):961-972
European journal of pain (London, England) 2018 May;22(5):961-972
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, Li Z, Liu Y, Li C
Brain research bulletin 2018 May;139:203-210
Brain research bulletin 2018 May;139:203-210
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Huang XF, Li JJ, Tao YG, Wang XQ, Zhang RL, Zhang JL, Su ZQ, Huang QH, Deng YH
RSC advances 2018 May 22;8(34):18926-18937
RSC advances 2018 May 22;8(34):18926-18937
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
IGF1 affects macrophage invasion and activation and TNF-α production in the sciatic nerves of female SOD1G93A mice.
Ji Y, Duan W, Liu Y, Liu Y, Liu C, Li Y, Wen D, Li Z, Li C
Neuroscience letters 2018 Mar 6;668:1-6
Neuroscience letters 2018 Mar 6;668:1-6
Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling.
Ji X, Wang H, Wu Z, Zhong X, Zhu M, Zhang Y, Tan R, Liu Y, Li J, Wang L
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 20;24:1633-1641
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 20;24:1633-1641
α-catenin SUMOylation increases IκBα stability and inhibits breast cancer progression.
Chen H, Xu Z, Li X, Yang Y, Li B, Li Y, Xia K, Wang J, Li S, Wang M, Wu H
Oncogenesis 2018 Mar 13;7(3):28
Oncogenesis 2018 Mar 13;7(3):28
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer.
Xue J, Li R, Zhao X, Ma C, Lv X, Liu L, Liu P
Chemico-biological interactions 2018 Mar 1;283:59-74
Chemico-biological interactions 2018 Mar 1;283:59-74
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper.
Liu J, Zhao H, Wang Y, Shao Y, Li J, Xing M
Environmental science and pollution research international 2018 Jun;25(16):15462-15473
Environmental science and pollution research international 2018 Jun;25(16):15462-15473
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer.
Xie M, Fu Z, Cao J, Liu Y, Wu J, Li Q, Chen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:286-294
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:286-294
Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice.
Chen S, Li R, Cheng C, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Wang H, Lu L, Xu GT, Tian H
Cell biology international 2018 Jul;42(7):877-889
Cell biology international 2018 Jul;42(7):877-889
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Yan X, Lei F, Hu Y, Nie L, Jia Q, Zhou H, Zhao F, Zheng Y
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus.
Sun X, Li J, Zhao H, Wang Y, Liu J, Shao Y, Xue Y, Xing M
Journal of inorganic biochemistry 2018 Jan;178:54-62
Journal of inorganic biochemistry 2018 Jan;178:54-62
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Chen J, Li D
International immunopharmacology 2018 Feb;55:1-8
International immunopharmacology 2018 Feb;55:1-8
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
Zeng HL, Yu FL, Zhang Z, Yang Q, Jin S, He X, Chen X, Shen Y, Cheng L, Guo L, Xu F
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Shen Z, Ma Y, Ji Z, Hao Y, Yan X, Zhong Y, Tang X, Ren W
Lipids in health and disease 2018 Feb 9;17(1):26
Lipids in health and disease 2018 Feb 9;17(1):26
Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS).
Yan L, Liu Y, Sun C, Zheng Q, Hao P, Zhai J, Liu Y
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 2;24:678-686
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 2;24:678-686
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Wang Y, Guan M, Zhao X, Li X
Pharmaceutical biology 2018 Dec;56(1):325-332
Pharmaceutical biology 2018 Dec;56(1):325-332
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Neat1-miRNA204-5p-PI3K-AKT axis as a potential mechanism for photodynamic therapy treated colitis in mice.
Wang K, Zhang Z, Liu K, Yang X, Zou H, Zhou J, Miao X, Chen W, Xiong L, Wen Y
Photodiagnosis and photodynamic therapy 2018 Dec;24:349-357
Photodiagnosis and photodynamic therapy 2018 Dec;24:349-357
Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice.
Yang CC, Chang CK, Chang MT, Shyur LF
International journal of cancer 2018 Dec 15;143(12):3248-3261
International journal of cancer 2018 Dec 15;143(12):3248-3261
lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma.
Li X, Zhao Q, Qi J, Wang W, Zhang D, Li Z, Qin C
International journal of oncology 2018 Aug;53(2):551-566
International journal of oncology 2018 Aug;53(2):551-566
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, Xu W, Zeng H
Redox biology 2018 Apr;14:237-249
Redox biology 2018 Apr;14:237-249
One-Shot Dual-Code Immunotargeting for Ultra-Sensitive Tumor Necrosis Factor-α Nanosensors by 3D Enhanced Dark-Field Super-Resolution Microscopy.
Ju S, Lee S, Chakkarapani SK, Kim K, Yu H, Kang SH
Analytical chemistry 2018 Apr 17;90(8):5100-5107
Analytical chemistry 2018 Apr 17;90(8):5100-5107
Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds.
Zhang X, Zheng W, Wang T, Ren P, Wang F, Ma X, Wang J, Huang X
Frontiers in pharmacology 2017;8:452
Frontiers in pharmacology 2017;8:452
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Dynamic changes of α-melanocyte-stimulating hormone levels in the serum of patients with craniocerebral trauma.
Du X, Dong B, Li C, Zhang F, Ji Y, Zhang J, Yin C
Experimental and therapeutic medicine 2017 Sep;14(3):2511-2516
Experimental and therapeutic medicine 2017 Sep;14(3):2511-2516
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M
Oncotarget 2017 Nov 17;8(58):98103-98116
Oncotarget 2017 Nov 17;8(58):98103-98116
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
Rapamycin suppresses Aβ(25-35)- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
Liu YC, Gao XX, Chen L, You XQ
Neuroscience 2017 Jul 4;355:188-199
Neuroscience 2017 Jul 4;355:188-199
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
Han X, Li B, Ye X, Mulatibieke T, Wu J, Dai J, Wu D, Ni J, Zhang R, Xue J, Wan R, Wang X, Hu G
British journal of pharmacology 2017 Dec;174(24):4751-4770
British journal of pharmacology 2017 Dec;174(24):4751-4770
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation.
Li M, Tang Y, Wu L, Mo F, Wang X, Li H, Qi R, Zhang H, Srivastava A, Ling C
Blood 2017 Aug 24;130(8):1041-1051
Blood 2017 Aug 24;130(8):1041-1051
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1(G93A) ALS Mice.
Wang W, Duan W, Wang Y, Wen D, Liu Y, Li Z, Hu H, Cui H, Cui C, Lin H, Li C
Neurochemical research 2017 Apr;42(4):986-996
Neurochemical research 2017 Apr;42(4):986-996
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50
Toxicology 2017 Apr 15;381:39-50
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead JF, Varghese Z, Ruan XZ, Chen Y
PloS one 2016;11(7):e0159512
PloS one 2016;11(7):e0159512
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, Zeng Y
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Fu J, Shi Q, Song X, Liu Z, Wang Y, Wang Y, Song E, Song Y
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway.
Wang Y, Duan W, Wang W, Di Wen, Liu Y, Liu Y, Li Z, Hu H, Lin H, Cui C, Li D, Dong H, Li C
Brain research 2016 Oct 1;1648(Pt A):1-10
Brain research 2016 Oct 1;1648(Pt A):1-10
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Zhai Y, Wu B, Li J, Yao XY, Zhu P, Chen ZN
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, Song E, Song Y
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, Shi D
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.
Liu X, Grogan TR, Hieronymus H, Hashimoto T, Mottahedeh J, Cheng D, Zhang L, Huang K, Stoyanova T, Park JW, Shkhyan RO, Nowroozizadeh B, Rettig MB, Sawyers CL, Elashoff D, Horvath S, Huang J, Witte ON, Goldstein AS
Cell reports 2016 Dec 6;17(10):2596-2606
Cell reports 2016 Dec 6;17(10):2596-2606
Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat.
Jiang W, Guo MH, Hai X
World journal of gastroenterology 2016 Dec 14;22(46):10180-10188
World journal of gastroenterology 2016 Dec 14;22(46):10180-10188
The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure.
Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, Mu D, Zhou K, Hua Y
Placenta 2015 Oct;36(10):1138-47
Placenta 2015 Oct;36(10):1138-47
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Wang D, Chen S, Liu M, Liu C
Chronobiology international 2015 Jun;32(5):615-26
Chronobiology international 2015 Jun;32(5):615-26
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
MiR-152 reduces human umbilical vein endothelial cell proliferation and migration by targeting ADAM17.
Wu Y, Huang A, Li T, Su X, Ding H, Li H, Qin X, Hou L, Zhao Q, Ge X, Fang T, Wang R, Gao C, Li J, Shao N
FEBS letters 2014 Jun 5;588(12):2063-9
FEBS letters 2014 Jun 5;588(12):2063-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- LPS treated RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 60291-1-Ig( TNF-a Antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TNF alpha antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human TNF alpha. This antibody recognizes human, mouse antigen. The TNF alpha antibody has been validated for the following applications: ELISA, WB, IHC analysis.
