Tissue expression
Cell line expression

TNF

gene product
DIF, TNF-alpha, TNFA, TNFSF2 
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
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5216 antibodies from 55 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
66 antibodies
Novus Biologicals
614 antibodies
Proteintech Group
9 antibodies
GeneTex
62 antibodies
antibodies-online
1737 antibodies
OriGene
139 antibodies
Invitrogen Antibodies
99 antibodies
Cusabio Biotech Co., Ltd
13 antibodies
Abnova Corporation
44 antibodies
Abgent
14 antibodies
LifeSpan BioSciences, Inc.
720 antibodies
NSJ Bioreagents
22 antibodies
Acris Antibodies GmbH
132 antibodies
Boster Biological Technology
12 antibodies
Biorbyt
135 antibodies
Antibodies.com
6 antibodies
Cell Signaling Technology, Inc
11 antibodies
Wuhan Fine Biotech Co., Ltd.
3 antibodies
Affinity Biosciences
3 antibodies
Signalway Antibody LLC
1 antibody
BioLegend
49 antibodies
Bioworld Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
22 antibodies
Abbiotec
7 antibodies
Aviva Systems Biology
22 antibodies
ABEOMICS Inc.
8 antibodies
Abbkine Scientific Co.Ltd.
6 antibodies
Creative Biolabs
680 antibodies
PeproTech Inc.
30 antibodies
QED Bioscience
2 antibodies
Enzo Life Sciences
3 antibodies
HUABIO Research
1 antibody
MyBioSource
44 antibodies
Leading Biology
30 antibodies
GenWay
56 antibodies
Creative Diagnostics
51 antibodies
Absolute Antibody
23 antibodies
Rockland Immunochemicals, Inc.
12 antibodies
ProSci
19 antibodies
ReliaTech GmbH
2 antibodies
Sino Biological Inc.
15 antibodies
SICGEN
1 antibody
Miltenyi Biotec
34 antibodies
United States Biological
98 antibodies
EMD Millipore
11 antibodies
Abbexa
40 antibodies
RayBiotech, Inc.
6 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
RabMAbs
5 antibodies
eBioscience, An Affymetrix Company
27 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody
Exalpha Biologicals, Inc.
4 antibodies
MedChemExpress LLC
1 antibody