RA0745

antibody from Oursmab

Targeting: TNF DIF, TNF-alpha, TNFA, TNFSF2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0745

Provider

Oursmab

Product name

Golimumab (Biosimilar Reference Antibody) (TNF)

Antibody type

Monoclonal

Description

Golimumab is a fully human monoclonal IgG1¦Ê antibody approved for the treatment of several chronic immune-mediated inflammatory diseases. It functions as a tumor necrosis factor-alpha (TNF-¦Á) inhibitor. By binding with high affinity to both soluble and transmembrane forms of TNF-¦Á, golimumab neutralizes its biological activity, preventing TNF-¦Á from interacting with its receptors, TNFR1 and TNFR2, on immune and tissue cells. This blockade inhibits the downstream pro-inflammatory signaling cascade that drives chronic inflammation, tissue damage, and symptoms in conditions like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, and plaque psoriasis.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.