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- Antigen structure
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- Product number
- 17590-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17590-1-AP, RRID:AB_2271853
- Product name
- TNF Alpha antibody
- Antibody type
- Polyclonal
- Description
- TNF Alpha antibody (Cat. #17590-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrated single-cell transcriptomics and proteomics elucidate the molecular mechanisms and detoxification strategy of rifampicin-induced hepatotoxicity.
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice.
Transcriptomics and Network Pharmacology Reveal Anti-Inflammatory and Anti-Oxidative Stress Mechanisms of Qingxuan Runmu Yin in Dry Eye Disease.
M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Dissolvable microneedles loaded with denosumab alleviate knee osteoarthritis in rodent and canine models by inhibiting macrophage senescence.
Porcine cells restrict human cell proliferation via cellular competition in a human-porcine mesenchymal stem cells co-culture model.
An astragalus polysaccharide-loaded hydrogel dressing enhances diabetic wound healing via dual-mode electrical stimulation.
Multifunctional selenium nanoplatforms for synergistic ferroptosis inhibition and immune microenvironment remodeling in oral mucositis.
Histone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.
Molybdenum nanodots reprogram inflammatory-driven osteolysis via bone immune remodeling.
RIPK1-driven calcium overload and lysosomal-mitochondrial dysfunction induce testicular necroptosis following DEHP exposure.
Subchronic arsenic exposure induced intestinal microbiota dysbiosis and intestinal inflammation via activating the NF-κB signaling pathway.
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
tFNA/GA@siRNOX4: A Multi-Mechanistic Nanodrug for the Amelioration of Cisplatin-Induced Acute Kidney Injury.
From multi-omics discovery to experimental validation: GPC4 mediates the anti-neuroinflammatory effects of Buyang Huanwu decoction via TLR4/NF-κB signaling in ischemic stroke with Qi deficiency and blood stasis syndrome.
FXR-mediated transcriptional regulation of KLF11 mitigates contrast-induced acute kidney injury via suppressing JAK2/STAT3 pathway.
Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects.
Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
Intervention effect of small extracellular vesicles derived from dental pulp stem cells on a high-altitude pulmonary edema model in male rats.
Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis.
Physcion-8-O-β-D-monoglucoside protects hepatocytes from TNF-α-mediated apoptosis by suppressing the PI3K/AKT/NF-κB signaling pathway.
Paeoniflorin alleviates nephrolithiasis by targeting serpine1 and inhibiting the NF-κB signaling pathway.
Disruption of sphingolipid metabolism triggers lung vascular inflammation and aging-like changes under hypoxia through VDAC1-mediated mitochondrial DNA release.
Rosa roxburghii Tratt Juice Inhibits Fluoride Exposure-Induced Bone Damage in Male Rats by Regulating the Homeostasis of the ROS/TNF-α/NF-κB Pathway.
Lactobacillus paragasseri LPG-9 reduces placental inflammation in intrahepatic cholestasis of pregnancy by regulating TGR5 in mice.
Nanocolloidal Hydrogel Coatings With Multiple Functions for Antithrombogenic Biointerfaces.
Long-term social isolation during adolescence exacerbated cardiac dysfunction after myocardial infarction.
CX3CL1/CX3CR1 axis dysregulation contributes to epileptogenic mechanisms in focal cortical dysplasia.
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling.
LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling.
Integrative Transcriptomics and Machine Learning Reveal the Association of CBX4 with Inflammation in Ulcerative Colitis as a Potential Epigenetic Regulator.
Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Epimedium polysaccharide alleviates adenine-induced oligoasthenozoospermia in mice by inhibiting ferroptosis and inflammation through TLR4/NF-κB and SLC7A11/GPX4 axis.
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway.
MST1 modulates inflammation by inhibiting BNIP3 -dependent mitophagy via the JNK/p53 pathway in acute lung injury.
Bie-Jia-Jian Pill: Inhibiting tumor glycolysis and promoting CD8(+) cell-mediated anti-tumor immunity by targeting HIF-1α-PI3K/AKT/mTOR and CCL20 in hepatocellular carcinoma.
BBB modulation-driven potentiation of antifungal therapy by melittin in fungal encephalitis.
Inhibition of endothelial ALOX12 mitigates cerebral ischemia-reperfusion injury by suppressing 12-HETE.
Chen's Jinshui Pills ameliorate diabetic retinopathy in mice and are associated with intestinal barrier protection and anti-inflammatory effects.
Design, synthesis, and biological evaluation of pyranone-carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease.
Eleutheroside B alleviates LPS-induced depressive-like behaviors by suppressing the TLR4/MyD88/NF-κB signaling pathway in the dentate gyrus.
Paeoniflorin Attenuates the Progression of Diabetic Kidney Disease by Regulating Macrophage Differentiation.
Xin-Ji-Er-Kang alleviates chronic heart failure by suppressing mtDNA/cGAS-STING signaling through NR3C1-mediated MFN2 upregulation.
Red nucleus IL-15 facilitates the development of neuropathic pain in male rats by inducing inflammatory factors: implying the involvement of NF-κB and p38 MAPK.
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
SanHuang decoction may suppress breast cancer by regulating M1 macrophage polarization via NF-κB signaling pathway: in vitro and in vivo studies.
Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.
Zhigancao decoction alleviates Parkinson's disease via inhibiting TNF/NF-κB and Ras/ERK-mediated neuroinflammation and apoptosis.
GCN2 activates macrophage autophagy to inhibit NLRP3 inflammasome-mediated acute lung injury.
Empagliflozin alleviates lipid deposition and inflammation in diabetic kidney disease by downregulating C1QC.
Integrating UPLC-HR-MS, network pharmacology and experimental validation to reveal the potential mechanism of Fuzheng Bixie granules in treating acute lung injury.
Microfluidic 3D-printed MSC-laden bioactive hydrogel for intrauterine adhesion prevention and endometrial regeneration.
The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP-1 Signaling in Colorectal Cancer.
Icaritin Ameliorates Cisplatin-Induced Mitochondrial Metabolic Dysfunction-Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy.
Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
Simvastatin Ameliorates Lipid Metabolism-Mediated Endothelial Inflammation and Tight Junction Impairment in Chronic Cerebral Hypoperfusion.
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects.
Human FGF1(ΔHBS) Gene Therapy as Treatment for Metabolic Dysfunction-Associated Steatohepatitis in ApoE-KO Mice.
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
DDX41 facilitates PD-L1-mediated immune escape in OSCC via the phase separation and activation STING pathway.
Short-chain fatty acids alleviated fluoride-induced neuroinflammation via the gut-brain axis in rats.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Sirtuin 5-mediated desuccinylation of PRDX6 inhibits ferroptosis and alleviates sepsis-associated acute kidney injury.
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Three-dimensional cell culture in vitro could better recapitulate the biological behavior of cells in vivo.
Resveratrol Attenuates Neuroinflammation and Myelination Deficits in Repeated Sevoflurane-Exposed Neonatal Mice.
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Macrophage CBX4 Potentiates Atherosclerosis by its SUMO E3 Ligase Activity.
Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy.
Mesoporous bioactive glass hybrid nanoparticles accelerate tendon-bone healing via synergistic angiogenesis and immunomodulation.
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
A dual-functional Janus nanofibrous membrane as an immunomodulatory barrier for periodontitis regeneration under diabetic conditions.
Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis.
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.
Zinc-Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing.
H(2)S-Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety.
Caffeine inhibited the hyperoxia-induced A2AR-ERK/p38 MAPK-IL-8 pathway in type II alveolar epithelial cells to suppress NETs formation in bronchopulmonary dysplasia.
Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM10-TREM2 pathway.
Neu5Ac promotes high-fat diet-induced progression of atherosclerosis in ApoE-deficient mice.
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Dual Single-Atom Engineered NADH Oxidase-Mimic Boosts In Situ NAD(+) Biotransformation for Targeted Myocardial Ischemia/Reperfusion Protection.
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Dangshen formula Shengmai-Yin suppresses atherosclerosis through restoring the gut microbiota and homeostatic efferocytosis.
Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
Biocompatible Pickering Emulsions from Andrias davidianus Byproducts for Promoting Burn Wound Healing.
RNF2 Modulates Lipid Metabolism and Inflammation in Alcohol-associated Liver Disease by Interacting with USP7.
Unveiling the Therapeutic Potential of Suyin Detoxification Prescription in Diabetic Nephropathy: A Comprehensive Study Integrating Clinical Efficacy, Network Pharmacology, and Molecular Mechanisms.
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Self-Assembled Carrier Free Oligomeric Proanthocyanidin/Tetrandrine Nanoparticles Ameliorate Osteoarthritis via Anti-Inflammatory and Anti-Ferroptotic Pathways.
Construction of Baicalein-Loaded Chitosan Nanoparticles for Staphylococcus aureus-Induced Lung Infection Remission.
Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice.
Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis.
Identification and Evaluation of Lipocalin-2 in Sepsis-Associated Encephalopathy via Machine Learning Approaches.
Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study.
Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-κB/IL-17A Pathway in Mice.
Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy.
Synergistic effects of platelet-rich fibrin and CTLA4Ig gene-transfected porcine skin on accelerating wound healing in a rat model of deep second-degree burns: a mechanistic study.
Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study.
cAMP-MFN2 signaling suppresses cochlear cell senescence and age-related hearing loss.
Neuroprotective mechanisms of valproic acid and alpha-lipoic acid in ALS: a network pharmacology-based investigation.
Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.
Distinct neuroprotective and anti-inflammatory effects of Kampo formulas ninjinyoeito and juzentaihoto in depression-like SAMP8 mice.
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia.
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
An integrative pharmacology-based study on the pharmacological activity and mechanism of xiaoji-chenpi formula (XCF) against MAFLD.
Emodin mitigates rheumatoid arthritis through direct binding to TNF-α.
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation.
Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice.
Two-in-one: multifunctional poloxamer hydrogel accelerates endometrial regeneration and fertility restoration through synergistic regulation of KGF-2 and NO.
Echinocystic acid in Momordica charantia L. exosome-like nanovesicles attenuates dengue virus-induced vascular leakage associated inflammatory mediators through macrophage metabolic reprogramming and HIF-1α/p300-CBP interaction.
Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation.
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
STAT1-IFITM3 promotes autophagy in epithelial cells to control Cryptosporidium parvum infection.
Identify of blood glucose metabolism regulation pathways and related proteins in the db/db mouse model through iTRAQ quantitative mass spectrometry.
Extraction, separation, structure identification and anti-inflammatory activity of polysaccharides from Lamiophlomis Rotata.
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Furongtongmai capsule alleviates neuroinflammation by downregulating the TLR4/MyD88/JNK pathway to promote the recovery of peripheral nerve compression.
Celastrol protected the MPTP-injected mice Parkinson's disease model via redox regulation of CDC37.
Blackcurrant polyphenol extract improves alcoholic liver disease through the FGF21-NET/c-FOS pathway.
Yolk extract-derived vitellogenin 2 ameliorates muscle atrophy in mice via the PI3K/AKT/mTOR pathway.
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Tongqiao huoxue decoction in improving vascular cognitive impairment in rats through PI3K-AKT pathway.
Self-assembled cyanidin-3-O-glucoside nanoparticles alleviate inflammation and ferroptosis induced by PRRSV infection.
Vitamin D against diabetic adipose tissue inflammation through SHP-1/STAT3 pathway.
RNF213 Knockdown and Inflammation Promote Angiogenesis and Phenotype Switching by JAK2/STAT3 Pathway in Moyamoya Disease.
Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity.
4-octyl Itaconate Attenuates Acute Pancreatitis and Associated Lung Injury by Suppressing Ferroptosis in Mice.
Intelligent hyaluronidase-responsive supramolecular nanoassemblies for programmable dual-drug delivery and NIR-II photothermal therapy of atherosclerosis.
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Magnesium hexacyanoferrate mitigates sepsis-associated encephalopathy through inhibiting microglial activation and neuronal cuproptosis.
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Chicoric acid exerts therapeutic effects in DSS-induced ulcerative colitis by targeting the USP9X/IGF2BP2 axis.
Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota-bile acid axis in mice by FXR signaling pathway.
Polychlorinated Biphenyl 138 Induces Toxicant-Associated Steatohepatitis via Hepatic Iron Overload and Adipose Inflammation.
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
Fecal microbiota transplantation promotes hair growth through gut microbiome and metabolic regulation.
Acetylcholine mediates nitro-PAHs induced inflammation and ameliorates the abnormalities in blood-brain barrier related proteins.
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair.
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Thrombopoietin mitigates neuronal death by enhancing mitophagy and suppressing NLRP3 inflammasome activation under oxygen-glucose deprivation conditions.
Saccharomyces boulardii Alleviates Ovalbumin-Induced Pyroptosis Through Cyba and IL-17 Signaling Pathway.
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Multifunctional hydrogel encapsulated with baicalin for full-layer regeneration of drug-resistant bacteria-infected wounds after radiotherapy.
Structure and preliminary anti-inflammatory activity of a novel sulfated α-glucan from Volutharpa ampullacea perryi.
Innovative DNA tetrahedron inspired by ancient mortise-and-tenon technique offers new immunotherapy strategy for metastatic breast cancer.
A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells.
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
Pumilio2 deficiency promotes iron-dependent macrophage inflammation via TfR1 upregulation in lupus.
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Theaflavin-3,3'-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice.
PGC1α alleviates M1 macrophage polarization through dual regulation of succinate metabolism and TRAF5 expression to mitigate TLR4/NF-κB-driven inflammatory cascades and myocardial ischemia/reperfusion injury.
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Exploring the effect and mechanism of baicalin on sepsis-induced acute lung injury based on network pharmacology and experimental verification.
Qihuang Yishen formula attenuates renal tubular injury by modulating inflammation via the cGAS/STING pathway in diabetic kidney disease.
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
The immunoregulator β-glucan produces antidepressant effects through microglia-mobilized astrocytic P2Y1R-BDNF signaling in the dentate gyrus.
Single-atom Ca nanozyme induces glioma death through Ca(2+)-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment.
Underlying metabolic syndrome exacerbates Vibrio vulnificus-induced acute kidney injury via systemic Th17/Treg dysregulation.
Absence of astrocytic ceruloplasmin reverses the senescence process with aging of learning and memory abilities.
Nuclear Factor Erythroid 2-Related Factor 2 Activator DDO-1039 Ameliorates Podocyte Injury in Diabetic Kidney Disease via Suppressing Oxidative Stress, Inflammation, and Ferroptosis.
A thermally stable bioactive chitosan scaffold with pH-responsive exosome adsorption and release function promotes wound healing.
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease.
Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD-MASH Transition by Disrupting Carnitine Biosynthesis.
S100A9 as a potential novel target for experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway.
Inflammation-responsive biomimetic nanoparticles with epigallocatechin-3-gallate for acute lung injury therapy via autophagy enhancement.
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Self-Assembly Oligomeric Anthocyanin-Based Core-Shell Structure of Nanoparticles Enhances the Delivery and Efficacy of Berberine in Osteoarthritis.
Geraniin attenuates isoproterenol-induced cardiac hypertrophy by inhibiting inflammation, oxidative stress and cellular apoptosis.
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
ROS scavenging and corneal epithelial wound healing by a self-crosslinked tissue-adhesive hydrogel based-on dual-functionalized hyaluronic acid.
p16INK4a Deletion Alleviated Obesity-Associated Kidney Fibrosis by Regulating Metabolic Reprogramming and the Inflammasome Pathway.
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
Citrulline regulates macrophage metabolism and inflammation to counter aging in mice.
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
Role of Adiponectin in Regulating Cytokines and Its Contribution to the Occurrence and Progression of Clinical Mastitis in Holstein Cows.
Resolvin D1 accelerates resolution of neuroinflammation by inhibiting microglia activation through the BDNF/TrkB signaling pathway.
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Nrf2 ameliorates defective autophagic processes and thereby inhibits ferroptosis in acute pancreatitis by suppressing Beclin1-Slc7a11 complex formation.
Medium- and long-chain triacylglycerols as enteral nutrition enhancing the nutritional status of postoperative rats undergoing chemotherapy by increasing the bioavailability of functional fatty acids.
Lycopene inhibits doxorubicin-induced heart failure by inhibiting ferroptosis through the Nrf2 signaling pathway.
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages.
Evaluation of anti-hyperuricemic and nephroprotective activities and discovery of new XOD inhibitors of Morus alba L. root bark.
Integration of single-cell RNA sequencing and network pharmacology to elucidate the effect of Yantiao Formula on alleviating ALI by regulating the polarization of alveolar macrophages.
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
Irisin Alleviates Impaired Mitochondrial Fusion via Enhancing PKA/SIRT3/mTOR Pathway in Hepatic Steatosis.
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring.
Polyvinyl alcohol/graphene oxide/dextran hydrogel doped copper oxide modified biochar with nano-enzymatic activity and multiple synergistic effects for accelerated diabetic wound healing.
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
Dopaminergic Neuron-Derived AIMP1 Promotes Neurodegeneration via CD23-Dependent Microglial Activation.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Targeted lipidomic reveals dietary LA/n-3 PUFAs regulate inflammation and redox status via oxylipins in bivalves.
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
LACC1 Enhances Polyamine Immunometabolism in Inflammatory Macrophages to Inhibit Atherosclerosis Progression.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Pelargonidin-3-O-galactoside Alleviates Acute Lung Injury Induced by Klebsiella pneumoniae by Targeting CD38-Mediated Pyroptosis.
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Exosomal miR-574-3p from adipose-derived mesenchymal stem modulates CRIM1/BMPs signaling to restrain chondrocytes hypertrophy and inflammatory response in knee osteoarthritis.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway.
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia.
Spinal astrocyte-derived M-CSF mediates microglial reaction and drives visceral hypersensitivity following DSS-induced colitis.
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
Calcium Fructoborate Improves Knee Osteoarthritis in Rats by Activating Hedgehog Signaling Through DDIT3.
Diosmetin attenuates the ubiquitination of epidermal hypoxia-inducible factor 1 alpha by diminishing the formation of RhoBTB3/PHD2 complex in ultraviolet radiation-induced sunburn in mice.
p38γ modulates ferroptosis in brain injury caused by ethanol and cerebral ischemia/reperfusion by regulating the p53/SLC7A11 signaling pathway.
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Steroid constituents of Solidago canadensis alleviate LPS-induced inflammation via AMPK regulated mitophagy/NLRP3 and NF-κB pathway.
The Rapid Activation of MYDGF Is Critical for Cell Survival in the Acute Phase of Retinal Regeneration in Fish.
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
Qifu Decoction Alleviates Lipopolysaccharide-Induced Myocardial Dysfunction by Inhibiting TLR4/NF-κB/NLRP3 Inflammatory Pathway and Activating PPARα/CPT Pathway.
18β-Glycyrrhetinic acid from Glycyrrhiza Uralensis protects colonic epithelium in ulcerative colitis by activating Wnt/β-catenin pathway to restore tight junction.
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Gut microbiota-derived indoleacetic acid attenuates neuroinflammation and neurodegeneration in glaucoma through ahr/rage pathway.
Comparison of the effects of Liraglutide, Tirzepatide, and Retatrutide on diabetic kidney disease in db/db mice.
A Novel Effect of Id2 in Microglia TNFα Regulation.
BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia.
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
Sini decoction alleviates inflammation injury after myocardial infarction through regulating arachidonic acid metabolism.
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
Znhit1 alleviates nitroglycerin-induced hyperalgesia in migraine mice via the inhibition of NOD-like receptor signaling pathway.
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.
The injury effect of osteopontin in sepsis-associated lung injury.
Engineered Therapeutic Bacteria with High-Yield Membrane Vesicle Production Inspired by Eukaryotic Membrane Curvature for Treating Inflammatory Bowel Disease.
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis.
The Ku protein family regulates hyperglycemia-induced vascular endothelial cell inflammation by modulating P300 levels.
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy.
Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson's disease model mice.
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Uncovering the mechanisms of Zhubi decoction against rheumatoid arthritis through an integrated study of network pharmacology, metabolomics, and intestinal flora.
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis.
TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway.
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway.
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse.
Neohesperidin protects against colitis-associated colorectal cancer in mice via suppression of the NF-κB/p65 and MAPK pathways.
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway.
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
Huangqi-Danshen decoction alleviates renal fibrosis through targeting SCD1 to modulate cGAS/STING signaling.
Multifunctional Injectable Bioadhesive with Toll-like Receptor 4 and Myeloid Differentiation Factor 2 Antagonistic Anti-inflammatory Potential for Periodontal Regeneration.
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Circular RNA APP contributes to Alzheimer's disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis.
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses.
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection.
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
RUNX1 Induces Central Neuropathic Pain by Activating Microglia and Triggering the Inflammatory Response in Spinal Cord Injury.
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Inhibition of 12/15-LOX hyperactivation mitigates cognitive decline in a chronic cerebral hypoperfusion mouse model and in H(2)O(2)-induced HT22 cells: therapeutic effects of brozopine.
Photothermal-triggered NO-releasing nanofiber membrane mitigates intervertebral disc degeneration via inflammation inhibition and matrix stabilization.
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Hyperhomocysteinaemia aggravates periodontitis by suppressing the Nrf2/HO-1 signalling pathway.
Intranasal LAG3 antibody infusion induces microglia-dependent antidepressant effect by mobilizing astrocytic P2Y1R-mediated BDNF synthesis in the hippocampus.
The multifaceted modulations by dapagliflozin in preventing hyperglycemia-induced diabetic nephropathy through glucose transporters and PPARα.
Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Comparative evaluation of the therapeutic efficacy between human amniotic epithelial cells and human umbilical cord mesenchymal stem cells in premature ovarian insufficiency.
Structural polysaccharide PCP1 from Polygonatum cyrtonema Hua attenuates atherosclerosis via dual-target suppression of CD36/MSR1 and TLR4/NF-κB pathways.
Brevilin A reverses colitis of inflammatory bowel disease via modulation of TNF-α signaling and microbiome dysregulation.
Reactive oxygen species-associated molecular landscape uncovers diagnostic and immune features in osteoarthritis.
Mitochondrial-Targeting Drug-Loaded Nanoparticles Reprogram Macrophage Metabolism via ROS/NO Co-elimination for Diabetic Wound Healing.
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
MXene-integrated microneedles reprogram diabetic-associated macrophages for deep-wound infection therapy and immunoprotection.
Synthesis, antibacterial activity, and mechanistic characterization of novel 9-substituted berberine derivatives.
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Ectopic engraftment of nociceptive neurons derived from hPSCs for pain relief and joint homeostasis.
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
Nebulized M2 macrophage-derived nanovesicles for the treatment of explosion-induced acute lung injury.
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
Danggui Buxue Decoction Combined with Borneol Improves Cyclophosphamide-Induced Myelosuppression by Inhibiting CDK2.
Exosomal tpi-miR-10a-5p from T. pisiformis cysticerci regulates the expression of inflammatory factors in rabbits by targeting MAP3K7.
Curcumin-alendronate carbon dots: A dual-logic strategy for precision treatment of periodontitis.
Deliver CEBPE via cartilage targeting Lipid nanoparticle to block CEBPE-LTF-STAT3 positive feedback loop for efficient treatment of cartilage endplate degeneration.
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Combined with PEG Hydrogel Alleviate Maternal Simulated Birth Injury in a Rat Model.
Stimulation of microglia leads to a rapid antidepressant effect by triggering astrocytic P2Y1Rs and promoting BDNF-mediated neurogenesis in the hippocampus.
Discovery of a CYP2E1 inhibitor and its therapeutic potential in severe acute pancreatitis.
Rehmannioside A alleviates renal inflammation and fibrosis in hypertensive nephropathy via AT1R/MAPK14/IL-17 signaling pathway.
Dihydroartemisinin restrains angiogenesis through the TNF-α pathway to enhance the efficacy of anti-PD-1 immunotherapy in breast cancer.
Methamphetamine Exposure Induces Neuronal Programmed Necrosis by Permeabilizing Mitochondria via the RIPK1-RIPK3-MLKL Axis.
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Baicalin Alleviates ADAM17/EGFR Axis-Induced Peritonitis in Weaned Piglets Infected by Glaesserella parasuis.
Inhibition of ADAM17: A New Therapeutic Strategy to Alleviate Zearalenone Toxin-Induced Liver Injury by Endoplasmic Reticulum Stress and Inflammation.
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
NOD2 promotes sepsis-induced neuroinflammation by increasing brain endoplasmic reticulum stress mediated by LACC1.
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula.
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
CEBPA as a potential hub gene for cutaneous inflammation in type 2 diabetes mellitus.
Pinocembrin alleviates renal ischemia-reperfusion injury/unilateral ureteral obstruction (UUO)-generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis.
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.
Sensitivity of Various Indicators in a Mouse Sensitive Skin Model Treatment with 4-tert-Butylcyclohexanol and Pimecrolimus.
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Oleanolic acid inhibits mesangial cell proliferation and inflammatory response in mesangial proliferative glomerulonephritis through IL-17/ERK/AKT pathway.
Jatrorrhizine retard obesity by modulating transcription factor c-Jun/c-Fos to downregulate Mmp12-mediated inflammation.
Anethole trithione mitigates LPS/D-Gal-induced acute liver injury by suppressing ROS production and NF-κB activity.
Inhibition of Zbp1-PANoptosome-mediated PANoptosis effectively attenuates acute pancreatitis.
The Potential of Siraitia grosvenorii to Promote Bone Regeneration via Modulating Macrophage Polarization: A Network Pharmacology and Experimental Study.
Vitamin D(3) alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats.
Exploring the Action Mechanism and Validation of the Key Pathways of Dendrobium officinale Throat-clearing Formula for the Treatment of Chronic Pharyngitis Based on Network Pharmacology.
Mechanistic study of celastrol-mediated inhibition of proinflammatory activation of macrophages in IgA nephropathy via down-regulating ECM1.
Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target.
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Exploring the effects of hypoxia and reoxygenation time on hepatocyte apoptosis and inflammation.
Exercise Attenuate Diaphragm Atrophy in COPD Mice via Inhibiting the RhoA/ROCK Signaling.
Angiotensin-(1-7) Modulates the Warburg Effect to Alleviate Inflammation in LPS-Induced Macrophages and Septic Mice.
Exercise preconditioning and resveratrol reduce the susceptibility of rats with obstructive jaundice to endotoxin and alleviate lung injury.
Rosa roxburghii fermented juice mitigates LPS-induced acute lung injury by modulation of intestinal flora and metabolites.
Vagal innervation limits brain injury by inhibiting gut-selective integrin-mediated intestinal immunocyte migration in intracerebral hemorrhage.
Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.
Antibacterial and antioxidant phlorizin-loaded nanofiber film effectively promotes the healing of burn wounds.
TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses.
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
Polystyrene microplastics facilitate renal fibrosis through accelerating tubular epithelial cell senescence.
Schisandrol B inhibits calcification of aortic valve by targeting p53 related inflammatory and senescence.
5-aminolevulinic acid photodynamic therapy for chronic wound infection in rats with diabetes.
Red nucleus mGluR1 and mGluR5 facilitate the development of neuropathic pain through stimulating the expressions of TNF-α and IL-1β.
Artemisia argyi polyphenols Attenuates DSS-induced colitis in mice by regulating the structural composition of gut microbiota.
Intermittent Fasting Targets Osteocyte Neuropeptide Y to Relieve Osteoarthritis.
Wenshenqianlie capsule improves benign prostatic hyperplasia via its anti-inflammatory and antioxidant effects.
Palmatine ameliorates N-methyl-N'-nitrosoguanidine-induced chronic atrophic gastritis through the STAT1/CXCL10 axis.
Vagus nerve stimulation (VNS) inhibits cardiac mast cells activation and improves myocardial atrophy after ischemic stroke.
The senescent marker p16INK4a enhances macrophage foam cells formation.
Exploring the efficacy and mechanism of Bailing capsule to improve polycystic ovary syndrome in mice based on intestinal-derived LPS-TLR4 pathway.
Construction of a mouse model for sensitive skin research.
Dual-Drug Nanomedicine Assembly with Synergistic Anti-Aneurysmal Effects via Inflammation Suppression and Extracellular Matrix Stabilization.
Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-α and IL-1β.
Prolonged exposure to a music-enriched environment mitigates acute noise-induced inflammation and apoptosis in the chicken spleen by modulating the Keap-1/Nrf2 and NF-κB pathways.
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Imperatorin attenuates CCl(4)-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways.
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Co-Mn Complex Oxide Nanoparticles as Potential Reactive Oxygen Species Scavenging Agents for Pulmonary Fibrosis Treatment.
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
The ASB@HNTs-PVA nanofiber membrane, possessing both anti-inflammatory and hemostatic activities, promotes the healing of T2D skin wounds.
Soluble Epoxide Hydrolase Inhibition Attenuates Proteinuria by Alleviating Renal Inflammation and Podocyte Injuries in Adriamycin-Induced Nephropathy.
Integrated single-cell and spatial transcriptomics reveal microenvironment disruptions by androgen in mouse ovary.
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Multifunctional chitosan-based hydrogels loaded with iridium nanoenzymes for skin wound repair.
Neuroprotective effect of emodin on Aβ(25-35)-induced cytotoxicity in PC12 cells involves Nrf2/GPX4 and TLR4/p-NF-κB/NLRP3 pathways.
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
ZnO nanoparticles induce melanoma-like lesions via recruiting dermal dendritic cells in barrier-damaged skin in mice.
Astrocytic purinergic signalling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes.
All-trans retinoic acid inhibits glioblastoma progression and attenuates radiation-induced brain injury.
Ginsenoside Rk3 Treats Corneal Injury Through the HMGB1/TLR4/NF-κB Pathway.
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.
Chitosan/rutin multifunctional hydrogel with tunable adhesion, anti-inflammatory and antibacterial properties for skin wound healing.
TBPH-induced lung injury is induced by mitochondrial-derived ds-DNA-mediated inflammatory response.
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Poly (vinyl alcohol)/sodium alginate/carboxymethyl chitosan multifunctional hydrogel loading HKUST-1 nanoenzymes for diabetic wound healing.
Artificial nonenzymatic antioxidant Prussian blue/KGM-BSA nanocomposite hydrogel dressing as ROS scavenging for diabetic wound healing.
Polarization to M1-type microglia in the hippocampus is involved in depression-like behavior in a mouse model of olfactory dysfunction.
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Platinum-Loaded Cerium Oxide Capable of Repairing Neuronal Homeostasis for Cerebral Ischemia-Reperfusion Injury Therapy.
Rap1GAP exacerbates myocardial infarction by regulating the AMPK/SIRT1/NF-κB signaling pathway.
Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury.
3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure.
Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice.
Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3.
Uterine Immunoprivileged Cells Restore Cardiac Function of Male Recipients After Myocardial Infarction.
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Xuebijing injection and its bioactive components alleviate nephrotic syndrome by inhibiting podocyte inflammatory injury.
Tetramethylpyrazine inhibits the inflammatory response by downregulating the TNFR1/IκB-α/NF-κB p65 pathway after spinal cord injury.
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Glycation promotes pulp calcification in Type 2 diabetes rat model.
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Schaftoside reduces inflammation in Aspergillus fumigatus keratitis through the inhibition of the TLR4/MyD88 pathway.
Rescuing Nucleus Pulposus Cells from ROS Toxic Microenvironment via Mitochondria-Targeted Carbon Dot-Supported Prussian Blue to Alleviate Intervertebral Disc Degeneration.
Characterization of Chitosan-Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application.
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs).
Xianling Lianxia formula enhances the inhibitory effects of trastuzumab on HER2-positive breast cancer.
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation.
Effects of chronic low-level lead (Pb) exposure on cognitive function and hippocampal neuronal ferroptosis: An integrative approach using bioinformatics analysis, machine learning, and experimental validation.
Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice.
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Two-electron oxidized polyphenol chemistry-inspired superhydrophilic drug-carrying coatings for the construction of multifunctional nasolacrimal duct stents.
Atractylenolide-III attenuates osteoarthritis by repolarizing macrophages through inactivating TLR4/NF-κB signaling.
Quercetin and Kaempferol inhibit HMC-1 activation via SOCE/NFATc2 signaling and suppress hippocampal mast cell activation in lipopolysaccharide-induced depressive mice.
MANF Alleviates Sevoflurane-Induced Cognitive Impairment in Neonatal Mice by Modulating Microglial Activation and Polarization.
Dihydroquercetin alleviates dopamine neuron loss via regulating TREM2 activation.
Collagen sponge scaffolds loaded with Trichostatin A pretreated BMSCs-derived exosomes regulate macrophage polarization to promote skin wound healing.
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Investigation of the underlying mechanism of Buyang Huanwu decoction in ischemic stroke by integrating systems pharmacology-proteomics and in vivo experiments.
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Hypoxia-inducible factor prolyl hydroxylase inhibitor alleviates heatstroke-induced acute kidney injury by activating BNIP3-mediated mitophagy.
Cordycepin Enhances the Therapeutic Efficacy of Doxorubicin in Treating Triple-Negative Breast Cancer.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway.
The Role of Grifola frondosa Polysaccharide in Preventing Skeletal Muscle Atrophy in Type 2 Diabetes Mellitus.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway.
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice.
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Structural elucidation and anti-psoriasis activity of a novel polysaccharide from Saussurea Costus.
Type 2 diabetes aggravates periodontitis-induced pathological changes in the dental pulp.
Chitosan-modified dihydromyricetin liposomes promote the repair of liver injury in mice suffering from diabetes mellitus.
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
Engineering Efferocytosis-Mimicking Nanovesicles to Regulate Joint Anti-Inflammation and Peripheral Immunosuppression for Rheumatoid Arthritis Therapy.
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
Evaluation of transurethral GreenLight laser-selective vaporization for refractory overactive bladder in women.
A classic prescription alleviates inflammation in CUMS model mice via modulating MYDGF/MAP4K4/NF-κB signaling pathway, verified through UPLC-HRMS and proteomics analysis.
Pathological polarizations from microglia to astrocyte contributes to spatial memory deficit in methamphetamine abstinence mice.
Pain Relief, Functional Recovery, and Chondroprotective Effects of Angelica gigas Nakai in Osteoarthritis Due to Its Anti-Inflammatory Property: An In Vitro and In Vivo Study.
The regulatory mechanism of cyclic GMP-AMP synthase on inflammatory senescence of nucleus pulposus cell.
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
The Contrasting Effects of Two Distinct Exercise Training Modalities on Exhaustive Exercise-Induced Muscle Damage in Mice May Be Associated with Alterations in the Gut Microbiota.
TAT-beclin1 treatment accelerates the development of atherosclerotic lesions in ApoE-deficient mice.
Effect of luteolin on oxidative stress and inflammation in the human osteoblast cell line hFOB1.19 in an inflammatory microenvironment.
Rescue of nucleus pulposus cells from an oxidative stress microenvironment via glutathione-derived carbon dots to alleviate intervertebral disc degeneration.
Ursolic acid molecules dock MAPK1 to modulate gut microbiota diversity to reduce neuropathic pain.
Porphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis.
Uric acid promotes interleukin-17 expression to cause kidney injury.
The P38MAPK/ATF2 signaling pathway is involved in PND in mice.
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
Acacetin inhibits activation of microglia to improve neuroinflammation after subarachnoid hemorrhage through the PERK signaling pathway mediated autophagy.
S-amlodipine induces liver inflammation and dysfunction through the alteration of intestinal microbiome in a rat model.
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Core-Shell Structured Nanozyme with PDA-Mediated Enhanced Antioxidant Efficiency to Treat Early Intervertebral Disc Degeneration.
Yi-shen-hua-shi granules modulate immune and inflammatory damage via the ALG3/PPARγ/NF-κB pathway in the treatment of immunoglobulin a nephropathy.
The protective effect of apolipoprotein H in paediatric sepsis.
The lncRNA GAS5 upregulates ANXA2 to mediate the macrophage inflammatory response during atherosclerosis development.
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Network pharmacology and in vivo evidence of the pharmacological mechanism of geniposide in the treatment of atherosclerosis.
Tafluprost promotes axon regeneration after optic nerve crush via Zn(2+)-mTOR pathway.
Marine bromophenols suppressed choroidal neovascularization by targeting HUWE1 through NF-κb signaling pathway.
Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages.
Liver toxicity in rats after subchronic exposure to HTP aerosol and cigarette smoke.
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway.
An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering.
Nanohybrid dual-network chitosan-based hydrogels: Synthesis, characterization, quicken infected wound healing by angiogenesis and immune-microenvironment regulation.
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
STING Activation in Macrophages and Microglia Drives Poststroke Inflammation: Implications for Neuroinflammatory Mechanisms and Therapeutic Interventions.
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Spatio-temporal expression of Sox2(+) progenitor cells regulates the regeneration of rat submandibular gland.
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway.
Jia Wei Qingxin Lotus Seed Drink ameliorates epithelial mesenchymal transition injury in diabetic kidney disease via inhibition of JMJD1C/SP1/ZEB1 signaling pathway.
Sphingosine-1-phosphate receptor 3 promotes neuronal apoptosis via the TNF-α/caspase-3 signaling pathway after acute intracerebral hemorrhage.
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
Involvement of necroptosıs and apoptosıs ın protectıve effects of cyclosporın a on ischemıa-reperfusıon injury in rat kıdney.
Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp.
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
Carbon monoxide as a negative feedback mechanism on HIF-1α in the progression of metabolic-associated fatty liver disease.
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling.
Membrane Fusion-Mediated Loading of Therapeutic siRNA into Exosome for Tissue-Specific Application.
Photocrosslinked carboxymethylcellulose-based hydrogels: Synthesis, characterization for curcumin delivery and wound healing.
PL-Relief(TM)plus Alleviates Atopic Dermatitis and Regulates Inflammatory Responses via Inhibiting NF-κB Signaling Pathway.
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
CCR5 antagonist maraviroc alleviates doxorubicin-induced neuroinflammation and neurobehavioral deficiency by regulating NF-κB/NLRP3 signaling in a breast cancer mouse model.
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Danshensu methyl ester attenuated LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway.
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Investigating the Mechanistic of Danhong Injection in Brain Damage Caused by Cardiac I/R Injury via Bioinformatics, Computer Simulation, and Experimental Validation.
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathway.
5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion.
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
VCAM1 Drives Vascular Inflammation Leading to Continuous Cortical Neuronal Loss Following Chronic Cerebral Hypoperfusion.
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Inhibition of Galectin-3 in a Rat Model of Epilepsy and Kainate-Activated BV2 Cells Limits Microglial Activation Through the NLRP3/Pyroptosis Pathway.
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis.
Palmitate lipotoxicity is closely associated with the fatty acid-albumin complexes in BV-2 microglia.
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.
Dapagliflozin promotes angiogenesis in hindlimb ischemia mice by inducing M2 macrophage polarization.
IL-37 counteracts inflammatory injury in the temporomandibular joint via the intracellular pathway.
The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Exploring the molecular mechanism of notoginsenoside R1 in sepsis-induced cardiomyopathy based on network pharmacology and experiments validation.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Locally controlled release of immunosuppressive promotes survival of transplanted adult spinal cord tissue.
Normothermic ex vivo heart perfusion with NLRP3 inflammasome inhibitor Mcc950 treatment improves cardiac function of circulatory death hearts after transplantation.
N-Acetylcysteine-Derived Carbon Dots for Free Radical Scavenging in Intervertebral Disc Degeneration.
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Glymphatic Dysfunction in Migraine Mice Model.
Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO-Induced Renal Fibrosis.
Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Epithelial-specific deletion of FAM20A leads to short root defects.
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
Role of SIRT2 in intestinal barrier under cold exposure.
Agaricus blazei Murrill Polysaccharide Attenuates Periodontitis via H(2) S/NRF2 Axis-Boosted Appropriate Level of Autophagy in PDLCs.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Role of corn silk for the treatment of Alzheimer's disease: A mechanism research based on network pharmacology combined with molecular docking and experimental validation.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.
MAGL inhibition relieves synovial inflammation and pain via regulating NOX4-Nrf2 redox balance in osteoarthritis.
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Interleukin-37 ameliorates atherosclerosis by regulating autophagy-mediated endothelial cell apoptosis and inflammation.
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
Sema3G activates YAP and promotes VSMCs proliferation and migration via Nrp2/PlexinA1.
SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis.
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
Protective effect of HDACIs in improves survival and organ injury after CLP-induced sepsis.
Protective effecs of baicalin magnesium on non-alcoholic steatohepatitis rats are based on inhibiting NLRP3/Caspase-1/IL-1β signaling pathway.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages.
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases.
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Ring finger protein 10 improves pirarubicin-induced cardiac inflammation by regulating the AP-1/Meox2 signaling pathway.
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Polystyrene microplastics mediate inflammatory responses in the chicken thymus by Nrf2/NF-κB pathway and trigger autophagy and apoptosis.
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Peptidomics Analysis Reveals the Buccal Gland of Jawless Vertebrate Lamprey as a Source of Multiple Bioactive Peptides.
A Comparative Study of Skin Changes in Different Species of Mice in Chronic Photoaging Models.
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway.
Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury.
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice.
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease.
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Gegen-Qinlian decoction alleviates anxiety-like behaviors in methamphetamine-withdrawn mice by regulating Akkermansia and metabolism in the colon.
ONO-2506 Can Delay Levodopa-induced Dyskinesia in the Early Stage.
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
A COMPARATIVE ANALYSIS TO DETERMINE THE OPTIMUM HISTONE DEACETYLASE INHIBITORS AND ADMINISTRATION ROUTE FOR IMPROVING SURVIVAL AND ORGAN INJURY IN RATS AFTER HEMORRHAGIC SHOCK.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats.
The effect and mechanism of excessive iodine on the endothelial function of human umbilical vein endothelial cells.
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis.
Exosomes From Adipose-Derived Stem Cells Suppress the Progression of Chronic Endometritis.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
Determination of the Anti-Oxidative Stress Mechanism of Isodon suzhouensis Leaves by Employing Bioinformatic and Novel Research Technology.
Ulinastatin ameliorates preeclampsia induced by N(gamma)-nitro-l-arginine methyl ester in a rat model via inhibition of the systemic and placental inflammatory response.
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Crocetin confers neuroprotection and is anti-inflammatory in rats with induced glaucoma.
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Acupuncture exerts preventive effects in rats of chronic unpredictable mild stress: The involvement of inflammation in amygdala and brain-spleen axis.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway.
PM(2.5) exposure increases dry eye disease risks through corneal epithelial inflammation and mitochondrial dysfunctions.
Collagen-EGCG Combination Synergistically Prevents UVB-Induced Skin Photoaging in Nude Mice.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
Ethanol extract of Paridis rhizoma attenuates carrageenan-induced paw swelling in rats by inhibiting the production of inflammatory factors.
Prolonged Antibiotic Use in a Preclinical Model of Gulf War Chronic Multisymptom-Illness Causes Renal Fibrosis-like Pathology via Increased micro-RNA 21-Induced PTEN Inhibition That Is Correlated with Low Host Lachnospiraceae Abundance.
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model.
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Fabrication of an Adhesive Small Intestinal Submucosa Acellular Matrix Hydrogel for Accelerating Diabetic Wound Healing.
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
circIFNGR2 regulating ankylosing spondylitis-associated inflammation through macrophage polarization.
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Up-regulation of PPAR-γ involved in the therapeutic effect of icariin on cigarette smoke-induced inflammation.
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
[Berberine inhibits autophagy and promotes apoptosis of fibroblast-like synovial cells from rheumatoid arthritis patients through the ROS/mTOR signaling pathway].
Diacylated anthocyanins from purple sweet potato (Ipomoeabatatas L.) attenuate hyperglycemia and hyperuricemia in mice induced by a high-fructose/high-fat diet.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
The Role of the Superior Cervical Sympathetic Ganglion in Ischemia Reperfusion-Induced Acute Kidney Injury in Rats.
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice.
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Acyloxyacyl hydrolase regulates microglia-mediated pelvic pain.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
PTBP-1 and TNF-α/NF-κB are involved in repair mechanisms of human umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury.
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promoted Wound Healing by Regulating PI3K/AKT/mTOR and SIRT1/NF-κB Pathways.
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Indole-3-Carbinol Selectively Prevents Chronic Stress-Induced Depression-but not Anxiety-Like Behaviors via Suppressing Pro-Inflammatory Cytokine Production and Oxido-Nitrosative Stress in the Brain.
Neutrophil Extracellular Traps Regulate HMGB1 Translocation and Kupffer Cell M1 Polarization During Acute Liver Transplantation Rejection.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
An Integrative Pharmacology Model for Decoding the Underlying Therapeutic Mechanisms of Ermiao Powder for Rheumatoid Arthritis.
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p.
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
The protective mechanism of folic acid on hyperhomocysteinemia-related arterial injury in spontaneously hypertensive rats: Folic acid against arterial inflammation.
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Glycosides from Buyang Huanwu Decoction inhibit atherosclerotic inflammation via JAK/STAT signaling pathway.
Ethanol extracts of Rhaponticum uniflorum (L.) DC inflorescence ameliorate LPS-mediated acute lung injury by alleviating inflammatory responses via the Nrf2/HO-1 signaling pathway.
Treadmill Exercise Modulates Intestinal Microbes and Suppresses LPS Displacement to Alleviate Neuroinflammation in the Brains of APP/PS1 Mice.
Hypoxic preconditioned aged BMSCs accelerates MI injury repair by modulating inflammation, oxidative stress and apoptosis.
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Upregulation of TACAN in the trigeminal ganglion affects pain transduction in acute pulpitis.
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
Single Cell Proteomics Profiling Reveals That Embryo-Secreted TNF-α Plays a Critical Role During Embryo Implantation to the Endometrium.
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
P38α deficiency in macrophages ameliorates murine experimental colitis by regulating inflammation and immune process.
Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats.
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway.
The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Blockage of transient receptor potential vanilloid 4 prevents postoperative atrial fibrillation by inhibiting NLRP3-inflammasome in sterile pericarditis mice.
Alterations in the jejunal microbiota and fecal metabolite profiles of rabbits infected with Eimeria intestinalis.
L-Se-methylselenocysteine loaded mucoadhesive thermogel for effective treatment of Vulvar candidiasis.
Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism.
Acrylonitrile exposure triggers ovarian inflammation and decreases oocyte quality probably via mitochondrial dysfunction induced apoptosis in mice.
2-undecanone protects against fine particles-induced heart inflammation via modulating Nrf2/HO-1 and NF-κB pathways.
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Gout-associated uric acid crystals induce tophi ulcerations and impair wound healing in a novel gouty ulcer model.
Pharmacological inhibition of epidermal growth factor receptor attenuates intracranial aneurysm formation by modulating the phenotype of vascular smooth muscle cells.
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
tRNA-derived fragment TRF365 regulates the metabolism of anterior cruciate ligament cells by targeting IKBKB.
Inhibition of Noncanonical Ca(2+) Oscillation/Calcineurin/GSK-3β Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.
C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis.
Injectable gelatin/oxidized dextran hydrogel loaded with apocynin for skin tissue regeneration.
Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice.
Placental trophoblast-specific overexpression of chemerin induces preeclampsia-like symptoms.
Combined royal jelly 10-hydroxydecanoic acid and aspirin has a synergistic effect against memory deficit and neuroinflammation.
Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways.
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1.
A novel Atlantic salmon (Salmo salar) bone collagen peptide delays osteoarthritis development by inhibiting cartilage matrix degradation and anti-inflammatory.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment.
Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway.
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Depletion of regulatory T cells exacerbates inflammatory responses after chronic cerebral hypoperfusion in mice.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Freshwater Clam Extract Attenuates Indomethacin-Induced Gastric Damage In Vitro and In Vivo.
Calcium phosphate cement with icariin-loaded gelatin microspheres as a local drug delivery system for bone regeneration.
Protective effect and mechanism of baicalin on lung inflammatory injury in BALB/cJ mice induced by PM2.5.
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI).
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Taurine inhibits necroptosis helps to alleviate inflammatory and injury induced by Klebsiella infection.
Anti-Inflammatory Activity of 4-(4-(Heptyloxy)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one via Repression of MAPK/NF-κB Signaling Pathways in β-Amyloid-Induced Alzheimer's Disease Models.
The effect of a chrysanthemum water extract in protecting the retina of mice from light damage.
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.
Chemical characteristics of Rhodiola Crenulata and its mechanism in acute mountain sickness using UHPLC-Q-TOF-MS/MS combined with network pharmacology analysis.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain.
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor.
Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis.
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
Macrophage contributes to radiation-induced anti-tumor abscopal effect on transplanted breast cancer by HMGB1/TNF-α signaling factors.
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Microarray analysis reveals a potential role of lncRNA expression in remote ischemic preconditioning in myocardial ischemia-reperfusion injury.
Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.
MNSFβ Regulates TNFα Production by Interacting with RC3H1 in Human Macrophages, and Dysfunction of MNSFβ in Decidual Macrophages Is Associated With Recurrent Pregnancy Loss.
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
A-Lipoic Acid Alleviates Folic Acid-Induced Renal Damage Through Inhibition of Ferroptosis.
CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.
Ibudilast Attenuates Folic Acid-Induced Acute Kidney Injury by Blocking Pyroptosis Through TLR4-Mediated NF-κB and MAPK Signaling Pathways.
Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease.
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging.
Orexin-A Regulates Follicular Growth, Proliferation, Cell Cycle and Apoptosis in Mouse Primary Granulosa Cells via the AKT/ERK Signaling Pathway.
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Baicalin ameliorates cigarette smoke-induced airway inflammation in rats by modulating HDAC2/NF-κB/PAI-1 signalling.
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
Neuroprotective effects of macamide from maca (Lepidium meyenii Walp.) on corticosterone-induced hippocampal impairments through its anti-inflammatory, neurotrophic, and synaptic protection properties.
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Inflammation protein quantification by multiple reaction monitoring mass spectrometry in lipopolysaccharide-stimulated THP-1 cells.
Screen of anti-migraine active compounds from Duijinsan by spectrum-effect relationship analysis and molecular docking.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determined by a network pharmacology approach.
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles.
miR‑4792 regulates inflammatory responses in Cryptococcus neoformans‑infected microglia.
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Effects of carotid baroreceptor stimulation on aortic remodeling in obese rats.
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Alleviation of acute pancreatitis-associated lung injury by inhibiting the p38 mitogen-activated protein kinase pathway in pulmonary microvascular endothelial cells.
The furin-S2' site in avian coronavirus plays a key role in central nervous system damage progression.
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats.
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Cordyceps acid alleviates lung cancer in nude mice.
Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation.
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Sanweidoukou decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: Studies in vivo and in vitro.
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Luteolin ameliorates LPS-induced acute liver injury by inhibiting TXNIP-NLRP3 inflammasome in mice.
Damage to the blood‑brain barrier and activation of neuroinflammation by focal cerebral ischemia under hyperglycemic condition.
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Critical Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers.
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Syringin exerts neuroprotective effects in a rat model of cerebral ischemia through the FOXO3a/NF-κB pathway.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction.
Resolvin E1 accelerates pulp repair by regulating inflammation and stimulating dentin regeneration in dental pulp stem cells.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
Hawthorn polyphenols reduce high glucose-induced inflammation and apoptosis in ARPE-19 cells by regulating miR-34a/SIRT1 to reduce acetylation.
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Raw and wine processed Schisandra chinensis attenuate anxiety like behavior via modulating gut microbiota and lipid metabolism pathway.
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy.
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction.
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Long-term efavirenz exposure induced neuroinflammation and cognitive deficits in C57BL/6 mice.
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Immunoresponsive Tissue-Engineered Oral Mucosal Equivalents Containing Macrophages.
METTL3/N6-methyladenosine/ miR-21-5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF-κB pathway activation.
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Regulatory effects of hawthorn polyphenols on hyperglycemic, inflammatory, insulin resistance responses, and alleviation of aortic injury in type 2 diabetic rats.
High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Silencing lncRNA TUG1 Alleviates LPS-Induced Mouse Hepatocyte Inflammation by Targeting miR-140/TNF.
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Gastroprotective Activity of the Total Flavones from Abelmoschus manihot (L.) Medic Flowers.
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells.
Effect of Moxibustion on the Intestinal Flora of Rats with Knee Osteoarthritis Induced by Monosodium Iodoacetate.
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Effect of AAV9-hIGF-1 on inflammatory reaction in mdx mice and its mechanism.
Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation.
Protective effect of astaxanthin against La(2)O(3) nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
Dihydroartemisinin prevents dextran sodium sulphate-induced colitisthrough inhibition of the activation of NLRP3 inflammasome and p38 MAPK signaling.
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats.
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa B signaling in hepatic stellate cells.
Gut microbiome-derived lactate promotes to anxiety-like behaviors through GPR81 receptor-mediated lipid metabolism pathway.
Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine.
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats.
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
MST4 modulates the neuro-inflammatory response by regulating IκBα signaling pathway and affects the early outcome of experimental ischemic stroke in mice.
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Dexmedetomidine Inhibits Neuroinflammation by Altering Microglial M1/M2 Polarization Through MAPK/ERK Pathway.
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection.
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8(+) T cells.
The effect of astaxanthin on inflammation in hyperosmolarity of experimental dry eye model in vitro and in vivo.
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Vagus Nerve Stimulation Attenuates Acute Skeletal Muscle Injury Induced by Ischemia-Reperfusion in Rats.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis.
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection.
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
Effects of ubiquitin-proteasome inhibitor on the expression levels of TNF-α and TGF-β1 in mice with viral myocarditis.
Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1.
Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway.
Macrophage polarization in human gingival tissue in response to periodontal disease.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity and inhibiting inflammation.
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy.
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis by regulating fatty acid degradation and microbial dysbiosis.
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Effects of intrahepatic cholestasis of pregnancy on hepatic function, changes of inflammatory cytokines and fetal outcomes.
Changes in expression of p53 and inflammatory factors in patients with ulcerative colitis.
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Antichronic Gastric Ulcer Effect of Zinc-Baicalin Complex on the Acetic Acid-Induced Chronic Gastric Ulcer Rat Model.
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Boxb mediate BALB/c mice corneal inflammation through a TLR4/MyD88-dependent signaling pathway in Aspergillus fumigatus keratitis.
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Liver injury induced in Balb/c mice by PM(2.5) exposure and its alleviation by compound essential oils.
Three-Dimensionally Printed Silk-Sericin-Based Hydrogel Scaffold: A Promising Visualized Dressing Material for Real-Time Monitoring of Wounds.
scAAV9-VEGF-165 inhibits neuroinflammatory responses and invasion of macrophages into the peripheral nervous system of ALS transgenic mice.
Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines.
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
HMGB1 mediates depressive behavior induced by chronic stress through activating the kynurenine pathway.
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation.
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine.
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Prediction and identification of B‑cell epitopes for tumor necrosis factor‑α.
Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice.
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus.
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Perfluorooctane Sulfonate Induces Autophagy-Dependent Apoptosis through Spinster 1-Mediated lysosomal-Mitochondrial Axis and Impaired Mitophagy.
p38 mitogen-activated protein kinase inhibition modulates nucleus pulposus cell apoptosis in spontaneous resorption of herniated intervertebral discs: An experimental study in rats.
Elevated Level of Circulating Platelet-derived Microparticles in Oral Cancer.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats.
MicroRNA-499 Rs3746444 polymorphism and biliary atresia.
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Relationship between irradiation-induced neuro-inflammatory environments and impaired cognitive function in the developing brain of mice.
Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo.
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Chen J, Zhang Q, Huang J, He H, Bai Y, An Y, Hao M, Zhao W, Li W, Feng S, Yang S, Liao J, Wong YK, Dai L, Du Q, Luo P, Wang J
International journal of biological sciences 2026;22(1):481-499
International journal of biological sciences 2026;22(1):481-499
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Shao C, Sun Y, Zhao J, Ju C, Yang T, Liu J, Zhou L, Jia R, Zhao F
Stem cells international 2026;2026:3343152
Stem cells international 2026;2026:3343152
Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice.
Li T, Ye LQ, Liu HF, Chen XH, Wang Y, Chen ZM, Zheng Y, Zeng WX, Li SE, Wan L
Journal of inflammation research 2026;19:538350
Journal of inflammation research 2026;19:538350
Transcriptomics and Network Pharmacology Reveal Anti-Inflammatory and Anti-Oxidative Stress Mechanisms of Qingxuan Runmu Yin in Dry Eye Disease.
Zhao S, Wang J, Liu Y, Hu X, Gu C, Yao J
Journal of inflammation research 2026;19:516780
Journal of inflammation research 2026;19:516780
M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Song J, Su G, Chen W, Xie X, Zhang Z
Frontiers in neurology 2026;17:1733679
Frontiers in neurology 2026;17:1733679
Dissolvable microneedles loaded with denosumab alleviate knee osteoarthritis in rodent and canine models by inhibiting macrophage senescence.
Ming C, Bi D, Tian H, Liu W, Li H, Hu Y, Song Z, Xu D, Xu H, Li H, Lan S, Xu W, Chen W, Li Q, Feng J, Cao Q, Wang X, Fan P, Zhu J, Yu W, Ming C, Dai Z, Liu Y, Tong W
Theranostics 2026;16(1):325-344
Theranostics 2026;16(1):325-344
Porcine cells restrict human cell proliferation via cellular competition in a human-porcine mesenchymal stem cells co-culture model.
Fan X, An X, Zhang T, Li Z, Dai X, Zhang X
Frontiers in cell and developmental biology 2026;14:1750289
Frontiers in cell and developmental biology 2026;14:1750289
An astragalus polysaccharide-loaded hydrogel dressing enhances diabetic wound healing via dual-mode electrical stimulation.
Chen Z, Huo X, Wu Z, Ji G, Liu B, Tian H, Tang T, Deng J, Zhao Q, Li F
Bioactive materials 2026 Sep;63:885-903
Bioactive materials 2026 Sep;63:885-903
Multifunctional selenium nanoplatforms for synergistic ferroptosis inhibition and immune microenvironment remodeling in oral mucositis.
Ouyang Q, Gao R, Li S, Liang J, Li P, Zhou W
Biomaterials 2026 Sep;332:124147
Biomaterials 2026 Sep;332:124147
Histone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.
Shi C, Yuan F, Chen X, Xu S, Ding Y, Wen H, Duan C, Wu T, Lu H, Hu J, Xu J, Jiang L
Redox biology 2026 May;92:104078
Redox biology 2026 May;92:104078
Molybdenum nanodots reprogram inflammatory-driven osteolysis via bone immune remodeling.
Fu Z, Hao W, Qin X, Wang H, Xie D, Zhang M, Ni D
Biomaterials 2026 May;328:123871
Biomaterials 2026 May;328:123871
RIPK1-driven calcium overload and lysosomal-mitochondrial dysfunction induce testicular necroptosis following DEHP exposure.
Ran M, Yi R, Zhang H, Sun X, Qiu T, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Ecotoxicology and environmental safety 2026 May;316:120163
Ecotoxicology and environmental safety 2026 May;316:120163
Subchronic arsenic exposure induced intestinal microbiota dysbiosis and intestinal inflammation via activating the NF-κB signaling pathway.
Cao S, Cai R, Xi S, Wang Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:115991
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:115991
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
Li J, Zhou J, Zhang G, Ding N, Kuang Z, Wang J, Liu N, Jia G, Jiang M, Wu S, Yang J, Ding X, Lei Z, Nie Y, Zhang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
tFNA/GA@siRNOX4: A Multi-Mechanistic Nanodrug for the Amelioration of Cisplatin-Induced Acute Kidney Injury.
Xu J, Jiang F, Lu J, Huai L, Zhang Y, Zhu X, Wang J
Advanced healthcare materials 2026 May;15(18):e04036
Advanced healthcare materials 2026 May;15(18):e04036
From multi-omics discovery to experimental validation: GPC4 mediates the anti-neuroinflammatory effects of Buyang Huanwu decoction via TLR4/NF-κB signaling in ischemic stroke with Qi deficiency and blood stasis syndrome.
Zhang C, Wu X, Yu Z, Xu G, Yang J, Shao C, Wan H
Journal of ethnopharmacology 2026 May 23;363:121375
Journal of ethnopharmacology 2026 May 23;363:121375
FXR-mediated transcriptional regulation of KLF11 mitigates contrast-induced acute kidney injury via suppressing JAK2/STAT3 pathway.
Su BW, Yang HX, Wang WH, Wen L, Cui XH, Bao YN, Ren HW, Wang GY, Hu WJ, Yuan RQ, Wen RK, Luan ZL
International immunopharmacology 2026 May 15;177:116494
International immunopharmacology 2026 May 15;177:116494
Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects.
Luo Z, Ma J, Yang Y, Zhang H, Du Y, Dai J, Wang Y, Zhang W, Ma X, Lai Y
Journal of orthopaedic translation 2026 Mar;57:101054
Journal of orthopaedic translation 2026 Mar;57:101054
Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
Xu H, Weng J, Bao Q, Jiang Y, Xiao C, Chen L
Biomedical reports 2026 Mar;24(3):36
Biomedical reports 2026 Mar;24(3):36
Intervention effect of small extracellular vesicles derived from dental pulp stem cells on a high-altitude pulmonary edema model in male rats.
Li X, Mao Z, Wang C, Liu Y, Jiang Y, Liu J, Yan X, Wang H
Physiological reports 2026 Mar;14(5):e70810
Physiological reports 2026 Mar;14(5):e70810
Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis.
Li H, Qiao Y, Ding M, Liu Y
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026 Mar-Apr;74(2):235-248
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026 Mar-Apr;74(2):235-248
Physcion-8-O-β-D-monoglucoside protects hepatocytes from TNF-α-mediated apoptosis by suppressing the PI3K/AKT/NF-κB signaling pathway.
Hu R, Chen Z, Chen T, Chen Z, Luo W, Xu W, Huang M, Nan L, Jia R, Zhang Y, Chen Y
Scientific reports 2026 Mar 9;16(1)
Scientific reports 2026 Mar 9;16(1)
Paeoniflorin alleviates nephrolithiasis by targeting serpine1 and inhibiting the NF-κB signaling pathway.
Sun Y, Zhang X, Chen X, Zhao J, Liu Y, He W
Urolithiasis 2026 Mar 5;54(1)
Urolithiasis 2026 Mar 5;54(1)
Disruption of sphingolipid metabolism triggers lung vascular inflammation and aging-like changes under hypoxia through VDAC1-mediated mitochondrial DNA release.
Xu J, Ge Y, Zhang B, He S, Cao Q, Li P, Bu Y, Bai Y, Zhang L, Tan G, Ma J, Xie M
Apoptosis : an international journal on programmed cell death 2026 Mar 3;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 3;31(3)
Rosa roxburghii Tratt Juice Inhibits Fluoride Exposure-Induced Bone Damage in Male Rats by Regulating the Homeostasis of the ROS/TNF-α/NF-κB Pathway.
Yang W, Ma L, Hu T, Zhang L, Wu K, Chen H, Zhang D, Luo P
Biological trace element research 2026 Mar 3;
Biological trace element research 2026 Mar 3;
Lactobacillus paragasseri LPG-9 reduces placental inflammation in intrahepatic cholestasis of pregnancy by regulating TGR5 in mice.
Huang W, Zhang J, Shan J, Shen W, Du P, Liu J, Guo X, Chen Z, Zeng W, Lin Q, Fan H
Communications biology 2026 Mar 26;9(1)
Communications biology 2026 Mar 26;9(1)
Nanocolloidal Hydrogel Coatings With Multiple Functions for Antithrombogenic Biointerfaces.
Ding T, Ren C, Meng L, Zhang X, Shi H, Yang B, Li Y
Advanced healthcare materials 2026 Mar 26;:e04424
Advanced healthcare materials 2026 Mar 26;:e04424
Long-term social isolation during adolescence exacerbated cardiac dysfunction after myocardial infarction.
Yao Y, Wang A, Di C, Guo D, Zhang S, Zong R, Qi R, Han Y
Translational psychiatry 2026 Mar 20;16(1)
Translational psychiatry 2026 Mar 20;16(1)
CX3CL1/CX3CR1 axis dysregulation contributes to epileptogenic mechanisms in focal cortical dysplasia.
Lei L, Yang S, Li Y, Tian J, Fang Y, Huang T, Chen S, Zhou L
Acta neuropathologica communications 2026 Mar 20;14(1)
Acta neuropathologica communications 2026 Mar 20;14(1)
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling.
Yu Z, Kuang J, Wan X, Liang C, Wu F, Shu Z, Liang W, Wan X, Gong J
In vitro cellular & developmental biology. Animal 2026 Mar 20;
In vitro cellular & developmental biology. Animal 2026 Mar 20;
LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling.
Lin L, Li X, Guo W, Xie J, Li X, Guan X, Zhao C, Yin H, Xu H
Cell reports. Medicine 2026 Mar 17;7(3):102658
Cell reports. Medicine 2026 Mar 17;7(3):102658
Integrative Transcriptomics and Machine Learning Reveal the Association of CBX4 with Inflammation in Ulcerative Colitis as a Potential Epigenetic Regulator.
Ma X, Liu G, Gong T, Liu X
Biomedicines 2026 Mar 17;14(3)
Biomedicines 2026 Mar 17;14(3)
Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
Zhang H, Liu Y, Zhang S, Wang Z, Zhang X, Zhang Y, Zhang J, Liang S, Li C, Su M, Tian Z, Luo L
Journal of nanobiotechnology 2026 Mar 16;24(1)
Journal of nanobiotechnology 2026 Mar 16;24(1)
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Hao R, Sun Y, Wang C, Wang Y, Li L, Sun H, Chen L
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
Xu D, Zhang W, Tao XR, Gao K, Zhao MN, Wang JW
Journal of ethnopharmacology 2026 Mar 1;358:121035
Journal of ethnopharmacology 2026 Mar 1;358:121035
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Duan Z, Yu C, Yu Q, Yang W, Zhang R, Ruan Q, Zhao Y, Yan S
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Epimedium polysaccharide alleviates adenine-induced oligoasthenozoospermia in mice by inhibiting ferroptosis and inflammation through TLR4/NF-κB and SLC7A11/GPX4 axis.
Tang KY, Ai W, Jiang XC, Xiao M, Zhou YY, Yu XM, Chen SH, Zhao JL
Reproductive biology 2026 Jun;26(2):101203
Reproductive biology 2026 Jun;26(2):101203
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Takahashi K, Kurokawa K, Kawaguchi R, Takeda H, Tsuji M
Neurochemistry international 2026 Jun;196:106152
Neurochemistry international 2026 Jun;196:106152
Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway.
Li J, Zhao Y, Yang Y, Dai Q, Tian R, Wang J, Ye J, Zhang L, Li L
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168230
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168230
MST1 modulates inflammation by inhibiting BNIP3 -dependent mitophagy via the JNK/p53 pathway in acute lung injury.
Song L, Peng Z, Wang X
Tissue & cell 2026 Jun;100:103392
Tissue & cell 2026 Jun;100:103392
Bie-Jia-Jian Pill: Inhibiting tumor glycolysis and promoting CD8(+) cell-mediated anti-tumor immunity by targeting HIF-1α-PI3K/AKT/mTOR and CCL20 in hepatocellular carcinoma.
Liu Y, Yang X, Qin M, Chen W, Liu C, Jiang W, Wang Y, Tan S, Sun H, Chen J, Sun H, He S
Journal of ethnopharmacology 2026 Jun 28;365:121554
Journal of ethnopharmacology 2026 Jun 28;365:121554
BBB modulation-driven potentiation of antifungal therapy by melittin in fungal encephalitis.
Li M, Ai J, Zhang C, Zhang Q, Li S, Jin H, Yu X
International immunopharmacology 2026 Jun 15;179:116633
International immunopharmacology 2026 Jun 15;179:116633
Inhibition of endothelial ALOX12 mitigates cerebral ischemia-reperfusion injury by suppressing 12-HETE.
Wang T, Zhang J, Lu G, Han D, Mi T, Ma X, Wang L, He Z, Niu J
Free radical biology & medicine 2026 Jul;250:134-152
Free radical biology & medicine 2026 Jul;250:134-152
Chen's Jinshui Pills ameliorate diabetic retinopathy in mice and are associated with intestinal barrier protection and anti-inflammatory effects.
Jiang Y, Ding J, Zhou M, Yang X, Liang Y, Zhao X, Wang J, Liao Y
Journal of ethnopharmacology 2026 Jul 15;366:121661
Journal of ethnopharmacology 2026 Jul 15;366:121661
Design, synthesis, and biological evaluation of pyranone-carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease.
Liu X, Xu J, Lin C, Gao X, Xie Y, Chen X, Huang Q, Ye R, Shi H, Zhang L, Ye ZC, Wu C, Zha D
Bioorganic chemistry 2026 Jul 15;176:109887
Bioorganic chemistry 2026 Jul 15;176:109887
Eleutheroside B alleviates LPS-induced depressive-like behaviors by suppressing the TLR4/MyD88/NF-κB signaling pathway in the dentate gyrus.
Wu S, Jiang Y, Zhai C, Li P, Yang H, Xu C, Wang Y, Liu JG, Zhang L
International immunopharmacology 2026 Jul 1;180:116727
International immunopharmacology 2026 Jul 1;180:116727
Paeoniflorin Attenuates the Progression of Diabetic Kidney Disease by Regulating Macrophage Differentiation.
Shi C, Li R, Deng L, Pan D, Fu Z, He G, Qu Y, Liu R, Wang X, Chen X, Hong Q
Phytotherapy research : PTR 2026 Jan;40(1):213-226
Phytotherapy research : PTR 2026 Jan;40(1):213-226
Xin-Ji-Er-Kang alleviates chronic heart failure by suppressing mtDNA/cGAS-STING signaling through NR3C1-mediated MFN2 upregulation.
Zhang R, Wu J, Wang D, Li K, Hou Y, Yu Y, Jin C, Wang C, Gao S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157714
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157714
Red nucleus IL-15 facilitates the development of neuropathic pain in male rats by inducing inflammatory factors: implying the involvement of NF-κB and p38 MAPK.
Zhang MM, Wang WT, Li YJ, Tao XX, Li K, Chen JM, Yang QQ, Tian X, Yang J, Yu YL, Xu YL, Wu JB, Wang JY, Zeng XY
Brain, behavior, and immunity 2026 Jan;131:106137
Brain, behavior, and immunity 2026 Jan;131:106137
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Zhang S, Xie Y, Zhang L, Qi Y, Liao Q, Xu C, Yang S, Zhou H, Tan Q, Qi S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
SanHuang decoction may suppress breast cancer by regulating M1 macrophage polarization via NF-κB signaling pathway: in vitro and in vivo studies.
Ying Y, Guo M, Ning Q, Wei Y, Qian J, Cai R
Translational cancer research 2026 Jan 31;15(1):33
Translational cancer research 2026 Jan 31;15(1):33
Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.
Tong X, Shi G, Fang Z, Tang S, Zhou B, Meng Q, Zhang P, Li H, Cai X, Wang Z, Zheng X, Chen W, Jiang G, Wang H, Jiang D, Li Q
Nature communications 2026 Jan 30;17(1)
Nature communications 2026 Jan 30;17(1)
Zhigancao decoction alleviates Parkinson's disease via inhibiting TNF/NF-κB and Ras/ERK-mediated neuroinflammation and apoptosis.
Zhang J, Yu X, Fang Y, Li W, Cui Q, Liu X, Jiang Y, Zhang Y, Xu C, Sun X, Lu Y
iScience 2026 Jan 16;29(1):114489
iScience 2026 Jan 16;29(1):114489
GCN2 activates macrophage autophagy to inhibit NLRP3 inflammasome-mediated acute lung injury.
Xie Y, Chen X, Gong X, Chen H, Xu S
International immunopharmacology 2026 Jan 1;168(Pt 1):115785
International immunopharmacology 2026 Jan 1;168(Pt 1):115785
Empagliflozin alleviates lipid deposition and inflammation in diabetic kidney disease by downregulating C1QC.
Shi S, Li W, Yang L, Zhang J, Wu X
Molecular and cellular biochemistry 2026 Feb;481(2):885-898
Molecular and cellular biochemistry 2026 Feb;481(2):885-898
Integrating UPLC-HR-MS, network pharmacology and experimental validation to reveal the potential mechanism of Fuzheng Bixie granules in treating acute lung injury.
Yang L, Wu Z, Li Y, Ren G, Spáčil R, Ren W, Xu H
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):4589-4605
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):4589-4605
Microfluidic 3D-printed MSC-laden bioactive hydrogel for intrauterine adhesion prevention and endometrial regeneration.
Song Y, Ma R, Yi B, Zhou Q, Li X, Zhou Y, Hua Y, Shang L, Zhu X
Materials today. Bio 2026 Feb;36:102742
Materials today. Bio 2026 Feb;36:102742
The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP-1 Signaling in Colorectal Cancer.
Hu Z, Xun J, Liu B, Jiang X, Han Y, Yang H, Gao Q, Gao R, Zhang A, Wu X, Zhang D, Li D, Li T, Yang S, Wang X, Yu X, Zhang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e14086
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e14086
Icaritin Ameliorates Cisplatin-Induced Mitochondrial Metabolic Dysfunction-Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy.
Luo P, Chen J, An Y, Meng K, Zhou W, Li W, Liu J, Zhao W, He W, Cao T, Huang J, Feng S, Yang S, Hu H, Liao J, He H, Hao M, Zhang Q, Wang J, Gao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e06712
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e06712
Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
Ma CS, Han B, Guo JR, Guo JF, Shi CK, Liu YX, Yi WJ, Zhang LY, Deng AJ, Wang YS, He MT
Journal of translational medicine 2026 Feb 7;24(1)
Journal of translational medicine 2026 Feb 7;24(1)
Simvastatin Ameliorates Lipid Metabolism-Mediated Endothelial Inflammation and Tight Junction Impairment in Chronic Cerebral Hypoperfusion.
Sun R, Li W, Ji X, Hu W, Zhao Y, Lu Y, Shang J, Hao X, Zhang J
Neuromolecular medicine 2026 Feb 6;28(1):9
Neuromolecular medicine 2026 Feb 6;28(1):9
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Shen T, Lin R, Zheng T, Yu J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects.
Li Y, Tong A, Xu P, Chang L, Fan J, Shan Z, Tong C, Liu B
RSC advances 2026 Feb 26;16(13):11633-11646
RSC advances 2026 Feb 26;16(13):11633-11646
Human FGF1(ΔHBS) Gene Therapy as Treatment for Metabolic Dysfunction-Associated Steatohepatitis in ApoE-KO Mice.
Li Y, Hui X, Gu C, Lin Q, Abdelbaset-Ismail A, Xu Z, Yadav S, Huang H, Xu J, Watson SE, Wintergerst KA, Cai L, Deng Z, Tan Y
Cells 2026 Feb 24;15(5)
Cells 2026 Feb 24;15(5)
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
Luo Z, Xu G, Li C, Sun Z, Chen H, Yang M, Ye Y, Chen Q, Xu B, Luo H, Sun B
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
DDX41 facilitates PD-L1-mediated immune escape in OSCC via the phase separation and activation STING pathway.
Tian Z, Cui H, Sun S, Lan Z, Zhong P, Liu W, Li B, Chen H, Zhu Z, Yang Y, Yu J, Lian J, Zhao Y, Yu G
NPJ precision oncology 2026 Feb 11;10(1)
NPJ precision oncology 2026 Feb 11;10(1)
Short-chain fatty acids alleviated fluoride-induced neuroinflammation via the gut-brain axis in rats.
Zhao WP, Zhu SQ, Yin ZH, Ommati MM, Zhang YW, Zhao J, Zhou BH, Wang HW
Environmental pollution (Barking, Essex : 1987) 2026 Feb 1;390:127503
Environmental pollution (Barking, Essex : 1987) 2026 Feb 1;390:127503
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
Sirtuin 5-mediated desuccinylation of PRDX6 inhibits ferroptosis and alleviates sepsis-associated acute kidney injury.
Lin W, Dong C, Jiang Q, Lou Y, Wang L, He Z
Redox report : communications in free radical research 2026 Dec 31;31(1):2657075
Redox report : communications in free radical research 2026 Dec 31;31(1):2657075
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Zhang J, Duan K, Liu Q, Chen S, Zheng H, Liu Y, Qian J, Yin M, Liu J, Li J, Li Z, Chen M, Huang X, Lin F, Gao M, Liao L
Bioactive materials 2026 Aug;62:1-16
Bioactive materials 2026 Aug;62:1-16
Three-dimensional cell culture in vitro could better recapitulate the biological behavior of cells in vivo.
Qi Z, Yang S, Fu C, Xu J, Li Q, Yan J, Shen A, Hu B
Tissue & cell 2026 Apr;99:103246
Tissue & cell 2026 Apr;99:103246
Resveratrol Attenuates Neuroinflammation and Myelination Deficits in Repeated Sevoflurane-Exposed Neonatal Mice.
Che J, Wu Y, Dong J, Shi C, Chen Y, He Z, Zhang X, Zhang J
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2026 Apr;86(2):e70123
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2026 Apr;86(2):e70123
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Pei X, Wang F, Liu X, Lei Y, Chen Y, Liu B, Sun R, Li P, Bi J, Liu S
Oncogene 2026 Apr;45(12):1128-1144
Oncogene 2026 Apr;45(12):1128-1144
Macrophage CBX4 Potentiates Atherosclerosis by its SUMO E3 Ligase Activity.
Zhao Z, Xu S, Ma J, Zhang Z, Liang S, Guo J
Cardiovascular drugs and therapy 2026 Apr;40(2):447-460
Cardiovascular drugs and therapy 2026 Apr;40(2):447-460
Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy.
Li Z, Wu B, Li W, Marsili E, Tang K, Sun K, Cao Z, Zhang Y, Huang H, Li X, Wang G
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(19):e72747
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(19):e72747
Mesoporous bioactive glass hybrid nanoparticles accelerate tendon-bone healing via synergistic angiogenesis and immunomodulation.
Chen Y, Yao H, Li C, Zhou Y, Ren J, Liu R, Wei J, Hao L
Materials today. Bio 2026 Apr;37:103004
Materials today. Bio 2026 Apr;37:103004
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Lyu J, Jiang S, Ma T, Zhang Y, Yu J, Zhang Z, Teng Z, Helili M, Cao S, Geng X, Wang X, Jiang J, Qiu J, Sun X, Liu X, Ma X
Materials today. Bio 2026 Apr;37:102871
Materials today. Bio 2026 Apr;37:102871
A dual-functional Janus nanofibrous membrane as an immunomodulatory barrier for periodontitis regeneration under diabetic conditions.
Wang F, Wang Y, Sheng J, Zhang K, Cao Y, Han X, Yan K, Wang X
Materials today. Bio 2026 Apr;37:102869
Materials today. Bio 2026 Apr;37:102869
Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis.
Ni W, He J, Zeng Z, Ke J, Lin R, Peng J, Deng K, Wen L, Chen Y, Zhang C, Li Y, Gu G
Molecular medicine reports 2026 Apr;33(4)
Molecular medicine reports 2026 Apr;33(4)
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
Tai C, Ling C, Yang Y, Mo N, Yao C, Lv S, Zhang B, Wang H, Chen C
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.
You T, Dai B, Ding X, He Z, Peng J, Tao S, Ye L, Song T, Fan Z, Chen N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985
Zinc-Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing.
Sun R, Wei X, Song Z, Luo J, Ye J, Zhang Y, Zhu L, Gao J, Zhang H, Zhu H, Wang X, Xu K
Advanced healthcare materials 2026 Apr;15(15):e05663
Advanced healthcare materials 2026 Apr;15(15):e05663
H(2)S-Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety.
Zhou M, Dou R, Wu R, Xu Y, Wang Y, Wang P, Li J, Lu P, Mao Y, Qian J, Zhang Y, Zhang J, Zhu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e20787
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e20787
Caffeine inhibited the hyperoxia-induced A2AR-ERK/p38 MAPK-IL-8 pathway in type II alveolar epithelial cells to suppress NETs formation in bronchopulmonary dysplasia.
Wang X, Song Y, Yu L, Song K
Pediatric research 2026 Apr 29;
Pediatric research 2026 Apr 29;
Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM10-TREM2 pathway.
Deng L, Wang Y, Shi C, Wu J, Yao J, Shen W, Zhang Z, Liu R, Wang X, Zhu H, Zhang L, Cai G, Zhou J, Hong Q, Chen X
Journal of advanced research 2026 Apr 24;
Journal of advanced research 2026 Apr 24;
Neu5Ac promotes high-fat diet-induced progression of atherosclerosis in ApoE-deficient mice.
Huang D, Yin C, Wang D
Experimental animals 2026 Apr 22;75(2):194-201
Experimental animals 2026 Apr 22;75(2):194-201
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Tian P, Du Q, Zeng F, Chen J, Wang P, Zhang L, Li Y
Molecular biology reports 2026 Apr 22;53(1)
Molecular biology reports 2026 Apr 22;53(1)
Dual Single-Atom Engineered NADH Oxidase-Mimic Boosts In Situ NAD(+) Biotransformation for Targeted Myocardial Ischemia/Reperfusion Protection.
Liu J, Guo X, Wang N, Zhang X, Wang X, Li G, Hou X, Yu L, Chen Y, Li R
Advanced materials (Deerfield Beach, Fla.) 2026 Apr 21;:e19122
Advanced materials (Deerfield Beach, Fla.) 2026 Apr 21;:e19122
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Wang Y, Wang J, Chang Z
Applied biochemistry and biotechnology 2026 Apr 17;
Applied biochemistry and biotechnology 2026 Apr 17;
Dangshen formula Shengmai-Yin suppresses atherosclerosis through restoring the gut microbiota and homeostatic efferocytosis.
Li Y, Wang F, Hu M, Li Y, Xia S, Zhou Y, Li W, Chen L, Yan L, Sun P, Wang L, Liu G, Wu D, Lu T, Zhang F, Zheng S, Li A, Lu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 16;156:158210
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 16;156:158210
Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.
Qu Y, Wang P, Wang D, Li B, Yang F
International immunopharmacology 2026 Apr 15;175:116447
International immunopharmacology 2026 Apr 15;175:116447
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
Li G, Fu B, Wang X, Lin H, Chen X, Zhang J
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
Biocompatible Pickering Emulsions from Andrias davidianus Byproducts for Promoting Burn Wound Healing.
Luo J, Wang M, Qiu L, Huang Q, Liu X, Hao L, Ye T, Shang W, Wang K, Wang H, Meng Y, Xu K, Li C
Biomaterials research 2025;29:0233
Biomaterials research 2025;29:0233
RNF2 Modulates Lipid Metabolism and Inflammation in Alcohol-associated Liver Disease by Interacting with USP7.
Yan Q, Fang Q, Chen Z, Chen L, Du J
International journal of biological sciences 2025;21(7):3306-3323
International journal of biological sciences 2025;21(7):3306-3323
Unveiling the Therapeutic Potential of Suyin Detoxification Prescription in Diabetic Nephropathy: A Comprehensive Study Integrating Clinical Efficacy, Network Pharmacology, and Molecular Mechanisms.
Wei T, Huang J, Wan B, Huang B, Cheng J, Shi C, Yong C, Li Y, Zhou E
Journal of diabetes research 2025;2025:e4566357
Journal of diabetes research 2025;2025:e4566357
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
Lin SH, Soetanto CG, Chiu WC, Cross TL, Kao NJ, Wu YR, Lin CI, Jha P
International journal of food science 2025;2025:4154633
International journal of food science 2025;2025:4154633
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Ma W, Ma Y, Bai Y, Guo C, Zhang Q, Su X
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Self-Assembled Carrier Free Oligomeric Proanthocyanidin/Tetrandrine Nanoparticles Ameliorate Osteoarthritis via Anti-Inflammatory and Anti-Ferroptotic Pathways.
Xing C, Wu Y, Huang Y, Li W, Wang X, Chen H
International journal of nanomedicine 2025;20:13165-13181
International journal of nanomedicine 2025;20:13165-13181
Construction of Baicalein-Loaded Chitosan Nanoparticles for Staphylococcus aureus-Induced Lung Infection Remission.
Wang J, Zhu R, Yang K, Lei Z, Zhang X, Sun Y, Zhang X
International journal of nanomedicine 2025;20:12009-12018
International journal of nanomedicine 2025;20:12009-12018
Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice.
Su Z, Chen Y, Liu Y, Cao J, Cui J, Chen H, Li Q
Frontiers in neuroscience 2025;19:1563428
Frontiers in neuroscience 2025;19:1563428
Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis.
Mei Y, Zheng Y, Zhang X, Hu T, Zheng X, Zhang C, Deng Q
Journal of inflammation research 2025;18:8243-8262
Journal of inflammation research 2025;18:8243-8262
Identification and Evaluation of Lipocalin-2 in Sepsis-Associated Encephalopathy via Machine Learning Approaches.
Hu J, Chen Z, Wang J, Xu A, Sun J, Xiao W, Yang M
Journal of inflammation research 2025;18:3843-3858
Journal of inflammation research 2025;18:3843-3858
Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study.
Jiang L, Lu Y, Yin P, Liu D, Duan C, Wang Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3477-3490
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3477-3490
Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-κB/IL-17A Pathway in Mice.
Wang J, Li Y, Tan C, Shao J, Tang W, Kong Q, Sheng W, Ding Z, Li F, Piao J, Lv D, Hu L, Wang Q, Jiang X
Journal of inflammation research 2025;18:1167-1189
Journal of inflammation research 2025;18:1167-1189
Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy.
He YX, Zhang R, Xie C, Ji SF, Deng WJ, Teng JF
Frontiers in aging neuroscience 2025;17:1608631
Frontiers in aging neuroscience 2025;17:1608631
Synergistic effects of platelet-rich fibrin and CTLA4Ig gene-transfected porcine skin on accelerating wound healing in a rat model of deep second-degree burns: a mechanistic study.
Li J, Xu C, Chen L, Lou J, Kong H, Fan Y
Frontiers in immunology 2025;16:1756818
Frontiers in immunology 2025;16:1756818
Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study.
Liu X, Tang M, Lu J, Kong Y, Shen W, Zhang C, Yang X
Frontiers in immunology 2025;16:1756582
Frontiers in immunology 2025;16:1756582
cAMP-MFN2 signaling suppresses cochlear cell senescence and age-related hearing loss.
Liu Y, Cao J, Cui J, Chen H, Qin S, Li Q, Su Z
Frontiers in immunology 2025;16:1715738
Frontiers in immunology 2025;16:1715738
Neuroprotective mechanisms of valproic acid and alpha-lipoic acid in ALS: a network pharmacology-based investigation.
Zhang D, Han L, Zhang W, Wang D, Huo D, Tan X, Su X, Wang M, Xu J, Cheng J, Wang J, Feng H
Frontiers in pharmacology 2025;16:1681929
Frontiers in pharmacology 2025;16:1681929
Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.
Tian C, Ma A, Song T, Zhao F, Huang J, Gao J, Yan H, Chen X
Frontiers in pharmacology 2025;16:1671678
Frontiers in pharmacology 2025;16:1671678
Distinct neuroprotective and anti-inflammatory effects of Kampo formulas ninjinyoeito and juzentaihoto in depression-like SAMP8 mice.
Maruko A, Ito N, Oshima K, Nishi A, Kobayashi Y, Okada N
Frontiers in pharmacology 2025;16:1600176
Frontiers in pharmacology 2025;16:1600176
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Wu J, Xie W, Xie Y, Mazhar M, Duan J
Frontiers in pharmacology 2025;16:1573693
Frontiers in pharmacology 2025;16:1573693
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia.
Zhao J, Fu Y, Qiu H
Frontiers in microbiology 2025;16:1555734
Frontiers in microbiology 2025;16:1555734
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Zhang P, Jin M, Zhang L, Cui Y, Dong X, Yang J, Zhang J, Wu H
Frontiers in pharmacology 2025;16:1540835
Frontiers in pharmacology 2025;16:1540835
An integrative pharmacology-based study on the pharmacological activity and mechanism of xiaoji-chenpi formula (XCF) against MAFLD.
Liang S, Dong Y, Chang Z, Guo P, Jia J, Yang G, Chen Y, Dong L, Xu X, Cai T, Li T, Fang Y, Sun W, Li L, Wang C, Song X
Frontiers in pharmacology 2025;16:1521111
Frontiers in pharmacology 2025;16:1521111
Emodin mitigates rheumatoid arthritis through direct binding to TNF-α.
Lu D, Tian X, Cao T, Chen S, Liu C, Zheng L, Zhou M, Peng X, Li Y, Liu T
Frontiers in pharmacology 2025;16:1520281
Frontiers in pharmacology 2025;16:1520281
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Zhu Q, Chen R, Wu X, Zhou Y, Wang Z, Zhang H, Zhu H, Sun L, Shuai Z
Theranostics 2025;15(13):6553-6571
Theranostics 2025;15(13):6553-6571
Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation.
He Y, Lu J, Luo Y, Pang R, Hu X, Ding L, Xiao H, Wang Y, Wang W
Frontiers in chemistry 2025;13:1568551
Frontiers in chemistry 2025;13:1568551
Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice.
Cheng W, Wang C, Ma M, Zhou Y
Frontiers in cell and developmental biology 2025;13:1529901
Frontiers in cell and developmental biology 2025;13:1529901
Two-in-one: multifunctional poloxamer hydrogel accelerates endometrial regeneration and fertility restoration through synergistic regulation of KGF-2 and NO.
Zhang Y, Wang X, Gu Q, Lu C, Zhao Y, Li X
Regenerative biomaterials 2025;12:rbaf062
Regenerative biomaterials 2025;12:rbaf062
Echinocystic acid in Momordica charantia L. exosome-like nanovesicles attenuates dengue virus-induced vascular leakage associated inflammatory mediators through macrophage metabolic reprogramming and HIF-1α/p300-CBP interaction.
Liu H, He J, Xu L, Chen Y, Wang X, Pang X, Yang H, Liang L, Chen S, Li S
Frontiers in medicine 2025;12:1653689
Frontiers in medicine 2025;12:1653689
Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation.
Song Z, Wu Y, Luo L, Hu Q, Wu S, Wu M, Zhang G
Frontiers in nutrition 2025;12:1612746
Frontiers in nutrition 2025;12:1612746
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
Wei YH, Zhou SM, Zhao W, Chen Q, Wang QH, Yu ML, Wei YY, Hu TJ
Frontiers in veterinary science 2025;12:1539448
Frontiers in veterinary science 2025;12:1539448
STAT1-IFITM3 promotes autophagy in epithelial cells to control Cryptosporidium parvum infection.
Cui L, Li T, Zhang J, Shen Y, Cao J
Life science alliance 2025 Sep;8(9)
Life science alliance 2025 Sep;8(9)
Identify of blood glucose metabolism regulation pathways and related proteins in the db/db mouse model through iTRAQ quantitative mass spectrometry.
Yue Y, Dong S, Wu Z, Dong Y, Chen Q, Wang H, Liu C, Yang D
Acta diabetologica 2025 Sep;62(9):1417-1428
Acta diabetologica 2025 Sep;62(9):1417-1428
Extraction, separation, structure identification and anti-inflammatory activity of polysaccharides from Lamiophlomis Rotata.
Jiang Q, Hu M, Li X, Zhang Q, Zhang X, Jiang M
International journal of biological macromolecules 2025 Sep;322(Pt 4):146943
International journal of biological macromolecules 2025 Sep;322(Pt 4):146943
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Sun X, Zhang T, Zhao Y, Yang H, Li Y, Sun X, Bian X
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Liu X, Ma B, Hu S, Li D, Pan C, Xu Z, Chen H, Wang Y, Wang H
Biomaterials 2025 Sep;320:123253
Biomaterials 2025 Sep;320:123253
Furongtongmai capsule alleviates neuroinflammation by downregulating the TLR4/MyD88/JNK pathway to promote the recovery of peripheral nerve compression.
Liu H, Zhang X, Gu Q, Zhao Y, Wang H, Li H, Zhou T, Zhang Y, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157082
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157082
Celastrol protected the MPTP-injected mice Parkinson's disease model via redox regulation of CDC37.
Liao W, Dong A, Hafeez F, Ye Q, Huang E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157067
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157067
Blackcurrant polyphenol extract improves alcoholic liver disease through the FGF21-NET/c-FOS pathway.
Zhao M, Li B, Huo J, Yang B, Zhou Y, Zhang Y, Meng X, Wang Y
Food & function 2025 Sep 29;16(19):7779-7795
Food & function 2025 Sep 29;16(19):7779-7795
Yolk extract-derived vitellogenin 2 ameliorates muscle atrophy in mice via the PI3K/AKT/mTOR pathway.
Li Y, Song P, Wang J, Tong Y, Hao X, Shi H, Ma P, Ji S, Yu X, Yan Y, Lu J, Luo X, Dong Y, Wang H
Food & function 2025 Sep 29;16(19):7663-7677
Food & function 2025 Sep 29;16(19):7663-7677
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Zhou C, Zhang J, Chen L, Yu Y, Sun Y, Pan Y, Cai S, Zhong P
BMC oral health 2025 Sep 26;25(1):1472
BMC oral health 2025 Sep 26;25(1):1472
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Wu Y, Yuan X, Ma J, Xu L, Li M, Zhao G, Wang Y
Veterinary research 2025 Sep 25;56(1):185
Veterinary research 2025 Sep 25;56(1):185
Tongqiao huoxue decoction in improving vascular cognitive impairment in rats through PI3K-AKT pathway.
Wu J, Wang J, Sun M, Zhang Y, Li X, Xu Y, Zhu B, Gu X
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120262
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120262
Self-assembled cyanidin-3-O-glucoside nanoparticles alleviate inflammation and ferroptosis induced by PRRSV infection.
Chen X, Pang Y, Amona FM, Liu Z, Wang F, Liang Y, Yang J, Zhang W, Fang X, Chen X
Journal of virology 2025 Sep 23;99(9):e0095425
Journal of virology 2025 Sep 23;99(9):e0095425
Vitamin D against diabetic adipose tissue inflammation through SHP-1/STAT3 pathway.
Wei X, Wang Y, Liu W, Zhang D, Zhou C, Jiang Z, Li W, Li X, Miao Y
International immunopharmacology 2025 Sep 23;162:115131
International immunopharmacology 2025 Sep 23;162:115131
RNF213 Knockdown and Inflammation Promote Angiogenesis and Phenotype Switching by JAK2/STAT3 Pathway in Moyamoya Disease.
Shen J, Wang Y, Qin Y, Chen G, Xu J, Li Y, Hou Y, Liu Y, Liu W
Molecular neurobiology 2025 Oct;62(10):12938-12950
Molecular neurobiology 2025 Oct;62(10):12938-12950
Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity.
Zhang L, Gong H, Gong X, Zhou B, Wang X, Fei S, Xia D, Xu C, Huang X
Bioactive materials 2025 Oct;52:213-227
Bioactive materials 2025 Oct;52:213-227
4-octyl Itaconate Attenuates Acute Pancreatitis and Associated Lung Injury by Suppressing Ferroptosis in Mice.
Lu S, Gong Y, He P, Qi M, Dong W
Inflammation 2025 Oct;48(5):3156-3168
Inflammation 2025 Oct;48(5):3156-3168
Intelligent hyaluronidase-responsive supramolecular nanoassemblies for programmable dual-drug delivery and NIR-II photothermal therapy of atherosclerosis.
Liang H, Ma Y, Wang M, Zhao C, Pang H, Liu H, Yu F, Cheng Z, Zhao L
Materials today. Bio 2025 Oct;34:102242
Materials today. Bio 2025 Oct;34:102242
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Gao X, Wu S, Yao Z, Shao Y, Feng J, Yuan Z, Mao H
Materials today. Bio 2025 Oct;34:102104
Materials today. Bio 2025 Oct;34:102104
Magnesium hexacyanoferrate mitigates sepsis-associated encephalopathy through inhibiting microglial activation and neuronal cuproptosis.
Zhang Y, Xin J, Zhao D, Chen G, Ji P, Liu P, Wei H, Wang H, Xia Y, Wang Y, Wang Z, Ren X, Huo M, Yu H, Yang J
Biomaterials 2025 Oct;321:123279
Biomaterials 2025 Oct;321:123279
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Zhang N, Zhang S, Liu X, Zuo YY, Cui YG, Wang F, Zhang JH, Chang YZ, Yu P
Free radical biology & medicine 2025 Oct;238:370-386
Free radical biology & medicine 2025 Oct;238:370-386
Chicoric acid exerts therapeutic effects in DSS-induced ulcerative colitis by targeting the USP9X/IGF2BP2 axis.
Chen W, Shan Y, Wang M, Liang R, Sa R
British journal of pharmacology 2025 Oct;182(20):4968-4983
British journal of pharmacology 2025 Oct;182(20):4968-4983
Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota-bile acid axis in mice by FXR signaling pathway.
Yuan T, Gao X, Wang X, Tang X, Liang Z, Yin Y, Liu S, Ou J, Su W, Zhang Z, Li X, Huang Q, Zhao D, Zhang H
Chinese medicine 2025 Oct 30;20(1):183
Chinese medicine 2025 Oct 30;20(1):183
Polychlorinated Biphenyl 138 Induces Toxicant-Associated Steatohepatitis via Hepatic Iron Overload and Adipose Inflammation.
Hwang HJ, Lee MH, Lee SH, Sung BJ, Kim JG, Seo DY, Hur DY, Yoo YH, Cheong J, Kim HY
Toxics 2025 Oct 30;13(11)
Toxics 2025 Oct 30;13(11)
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
Su Y, Lu J, Liang F, Cheng J
Biomolecules 2025 Oct 24;15(11)
Biomolecules 2025 Oct 24;15(11)
Fecal microbiota transplantation promotes hair growth through gut microbiome and metabolic regulation.
Tian Y, Jin W, Jin X, Wang Y, Wu R, Yu R, Jiang J, Zhu M
Life sciences 2025 Oct 15;379:123887
Life sciences 2025 Oct 15;379:123887
Acetylcholine mediates nitro-PAHs induced inflammation and ameliorates the abnormalities in blood-brain barrier related proteins.
Shang Y, Wang H, Huang J, An J, Ren G, Wang Y, Tang Q, Qiu X, Xu B
Ecotoxicology and environmental safety 2025 Oct 15;305:119173
Ecotoxicology and environmental safety 2025 Oct 15;305:119173
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
Song SY, Shan CC, Zhou PP, Xu WL, Tan Y, Zhou XQ, Huang LJ, Yan QH, Yu JY
World journal of diabetes 2025 Oct 15;16(10):109568
World journal of diabetes 2025 Oct 15;16(10):109568
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair.
Liu Y, Wang D, Zheng W, Wang Y, Wang P, Zhao Y, Liu X, Shi Y, Wang Y, Zhou N, González FE, Sun H, Zhou D, Xu X
Journal of nanobiotechnology 2025 Oct 10;23(1):649
Journal of nanobiotechnology 2025 Oct 10;23(1):649
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Yu X, Li X, Wang Y, Yu X, Guo X, Wang C, Wang F
International immunopharmacology 2025 Oct 10;163:115255
International immunopharmacology 2025 Oct 10;163:115255
Thrombopoietin mitigates neuronal death by enhancing mitophagy and suppressing NLRP3 inflammasome activation under oxygen-glucose deprivation conditions.
Li L, Zhang Y, Zhong J, Kong H, Liu Y, Chen H, Fang X, Zhong Z, Xue H, Yang M, Chen C
American journal of physiology. Cell physiology 2025 Oct 1;329(4):C1173-C1187
American journal of physiology. Cell physiology 2025 Oct 1;329(4):C1173-C1187
Saccharomyces boulardii Alleviates Ovalbumin-Induced Pyroptosis Through Cyba and IL-17 Signaling Pathway.
Chen Z, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Molecular nutrition & food research 2025 Nov;69(21):e70194
Molecular nutrition & food research 2025 Nov;69(21):e70194
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Ju J, Wang C, Nie F, Tian H, Yin Q, Liu J, Wang S, Yang P, Du Y
International endodontic journal 2025 Nov;58(11):1725-1737
International endodontic journal 2025 Nov;58(11):1725-1737
Multifunctional hydrogel encapsulated with baicalin for full-layer regeneration of drug-resistant bacteria-infected wounds after radiotherapy.
Yuan R, Du S, Pan S, Lin Z, Zhang N, Zhang C, Zeng Q, Wei Y, Wu Y, Tao L
Bioactive materials 2025 Nov;53:20-31
Bioactive materials 2025 Nov;53:20-31
Structure and preliminary anti-inflammatory activity of a novel sulfated α-glucan from Volutharpa ampullacea perryi.
Chen Y, Qin Y, Yi H, Cui X, Wang X, Xu X, Chen Y, Li F, Wang W
International journal of biological macromolecules 2025 Nov;329(Pt 2):147806
International journal of biological macromolecules 2025 Nov;329(Pt 2):147806
Innovative DNA tetrahedron inspired by ancient mortise-and-tenon technique offers new immunotherapy strategy for metastatic breast cancer.
Zhang N, Qian L, Xu C, Duan F, Ma Y, Zhou L, Zhang Y, Ma Y, Lin Q, Lu K
Biomaterials 2025 Nov;322:123390
Biomaterials 2025 Nov;322:123390
A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells.
Zhang G, Wang Z, He M, Kong L, Yushanjiang S, Jin L, Zhao R, Ma Z, Pan Y, Hu Y, Nie L, Yuan D
Reproductive sciences (Thousand Oaks, Calif.) 2025 Nov;32(11):3587-3598
Reproductive sciences (Thousand Oaks, Calif.) 2025 Nov;32(11):3587-3598
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
Li Y, Wang K, Min Q, Lu H, Zhang G, Yan J
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
Pumilio2 deficiency promotes iron-dependent macrophage inflammation via TfR1 upregulation in lupus.
Wang X, Han X, Feng R, Qiu W, Jiang L, Duan X, Deng GM
Free radical biology & medicine 2025 Nov;239:513-527
Free radical biology & medicine 2025 Nov;239:513-527
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
Qin X, Liu J, Zhao X, Wang L, Liu X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Theaflavin-3,3'-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice.
Tang MG, Xiong LG, Huang JA, Hara Y, Zhang S, Liu ZH, Liu AL
The Journal of nutritional biochemistry 2025 Nov;145:110031
The Journal of nutritional biochemistry 2025 Nov;145:110031
PGC1α alleviates M1 macrophage polarization through dual regulation of succinate metabolism and TRAF5 expression to mitigate TLR4/NF-κB-driven inflammatory cascades and myocardial ischemia/reperfusion injury.
Leng J, Cao Z, Li L, Hu D, Luo Y, Tu B, Cao X, Tao R, Jiang Y, Tie H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Nov 6;74(1):156
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Nov 6;74(1):156
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Long T, Li X, Zhou Y, Zhu C, Zhang M, Li M, Wei Z
Gene 2025 Nov 5;971:149800
Gene 2025 Nov 5;971:149800
Exploring the effect and mechanism of baicalin on sepsis-induced acute lung injury based on network pharmacology and experimental verification.
Wang P, Zhang R, Liu M, Gao J, Zhang Y, Liu X, Li C, Zhao Y, Zhu T, Zhao X, Deng Z
Scientific reports 2025 Nov 25;15(1):41959
Scientific reports 2025 Nov 25;15(1):41959
Qihuang Yishen formula attenuates renal tubular injury by modulating inflammation via the cGAS/STING pathway in diabetic kidney disease.
Guo Y, Xue T, Meng X, Yan P, Zhang M, Zhang Q, Li T, Shi K, Zhang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157399
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157399
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Yang H, Shen T, Qi Z, Yang Z, Zhang M, Jiang J, Sun Z, Lu C
Neuropharmacology 2025 Nov 15;279:110638
Neuropharmacology 2025 Nov 15;279:110638
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
Li J, Cui H, Sun X, Zhu L, Li J, Liu R, Li Z
International immunopharmacology 2025 Nov 14;165:115509
International immunopharmacology 2025 Nov 14;165:115509
The immunoregulator β-glucan produces antidepressant effects through microglia-mobilized astrocytic P2Y1R-BDNF signaling in the dentate gyrus.
Song R, Yang R, Lu X, Gu Y, Li F, Hu W, Chen Z, Zhang L, Huang C, Liu L
International immunopharmacology 2025 Nov 14;165:115494
International immunopharmacology 2025 Nov 14;165:115494
Single-atom Ca nanozyme induces glioma death through Ca(2+)-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment.
Jin Z, Li X, Hou X, Hu J, Zhuo Y, Shi J, Xu T, Zhao Q, Jing Z
Journal of nanobiotechnology 2025 Nov 13;23(1):716
Journal of nanobiotechnology 2025 Nov 13;23(1):716
Underlying metabolic syndrome exacerbates Vibrio vulnificus-induced acute kidney injury via systemic Th17/Treg dysregulation.
More MP, Saha P, Roy S, Trivedi A, Chatterjee S
American journal of physiology. Renal physiology 2025 Nov 1;329(5):F627-F644
American journal of physiology. Renal physiology 2025 Nov 1;329(5):F627-F644
Absence of astrocytic ceruloplasmin reverses the senescence process with aging of learning and memory abilities.
Li ZD, Kang S, Li H, Yu P, Xie R, Li C, Jing Q, Gong Z, Li L, Li Z, Geng M, Zhang Z, Li Y, Chang YZ
Redox biology 2025 May;82:103611
Redox biology 2025 May;82:103611
Nuclear Factor Erythroid 2-Related Factor 2 Activator DDO-1039 Ameliorates Podocyte Injury in Diabetic Kidney Disease via Suppressing Oxidative Stress, Inflammation, and Ferroptosis.
Liu X, Zhai X, Wang X, Zhu X, Wang Z, Jiang Z, Bao H, Chen Z
Antioxidants & redox signaling 2025 May;42(13-15):787-806
Antioxidants & redox signaling 2025 May;42(13-15):787-806
A thermally stable bioactive chitosan scaffold with pH-responsive exosome adsorption and release function promotes wound healing.
Yuan J, Li M, He X, Hou Q, Fu X, Hao J
International journal of biological macromolecules 2025 May;306(Pt 3):141552
International journal of biological macromolecules 2025 May;306(Pt 3):141552
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Cao MM, Guo Z, Wang J, Ma HY, Qin XY, Hu Y, Lan R
Free radical biology & medicine 2025 May;232:340-352
Free radical biology & medicine 2025 May;232:340-352
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease.
Sun F, Ma Y, Li D, Yang Q, Yuan T, Liu T, Tian X, Zhu Z, Zheng W, Wang Y, Wang W
Basic & clinical pharmacology & toxicology 2025 May;136(5):e70036
Basic & clinical pharmacology & toxicology 2025 May;136(5):e70036
Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD-MASH Transition by Disrupting Carnitine Biosynthesis.
Lian S, Lu M, Jiajing L, Zhang B, Fang Y, Wang X, Zheng M, Ni Y, Xu G, Yang Y, Jiang R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2410602
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2410602
S100A9 as a potential novel target for experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Zhao J, Zhou M, Yang C, Liu YW, Yang T, Sun B, Li B, Zheng J, Dai S, Yang Z, Wang X
Biomarker research 2025 May 9;13(1):72
Biomarker research 2025 May 9;13(1):72
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
Liu J, Li Z, Liu W, Jiang Z, Zhang X, Yuan Y, Shen Y
International immunopharmacology 2025 May 8;154:114559
International immunopharmacology 2025 May 8;154:114559
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Wang H, Yang Y, Li T, Chang S, Zhu Y, Liu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway.
Li X, Ding L, Li Z, Cao Z, Li M, Yin K, Song S, Cao L, Xia Q, Wang Z, Zhao D, Tong X, Li X, Wang Z
Chinese medicine 2025 May 26;20(1):69
Chinese medicine 2025 May 26;20(1):69
Inflammation-responsive biomimetic nanoparticles with epigallocatechin-3-gallate for acute lung injury therapy via autophagy enhancement.
Han Y, Liu T, Wei R, Dai C, Huang X, Hu D
iScience 2025 May 16;28(5):112318
iScience 2025 May 16;28(5):112318
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
Liu Y, Zhao W, Lv X, Wu G, Zhou X, Tian H, Qv X, Sun H, He Y, Zhang Y, Wang C, Tian J
International immunopharmacology 2025 May 16;155:114588
International immunopharmacology 2025 May 16;155:114588
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Zhang M, Hong Y, Yu W, Zhang Y, Shen Y, Cai Z, Jia R, Pang Z, Huang X, Huang Y, Gao X, Liu Y, Qu Y, Yang Q, Zhang X, Zhu A, Ao H
International immunopharmacology 2025 May 16;155:114513
International immunopharmacology 2025 May 16;155:114513
Self-Assembly Oligomeric Anthocyanin-Based Core-Shell Structure of Nanoparticles Enhances the Delivery and Efficacy of Berberine in Osteoarthritis.
Huang Y, Wang X, Chen H, Wu Y, Lv L, Chen F, Lei H, Xing C
ACS biomaterials science & engineering 2025 May 12;11(5):2739-2752
ACS biomaterials science & engineering 2025 May 12;11(5):2739-2752
Geraniin attenuates isoproterenol-induced cardiac hypertrophy by inhibiting inflammation, oxidative stress and cellular apoptosis.
Ding J, Zhang S, Li Q, Xia B, Wu J, Lu X, Huang C, Yuan X, You Q
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 May 1;29(3):307-319
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 May 1;29(3):307-319
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Molecular neurobiology 2025 Mar;62(3):3833-3847
Molecular neurobiology 2025 Mar;62(3):3833-3847
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
Wen L, Lin X, Hu D, Li J, Xie K, Li S, Su S, Duan X, Zhong G, Lin Y, Chen Y, Xu T, Zeng Q
Atherosclerosis 2025 Mar;402:119109
Atherosclerosis 2025 Mar;402:119109
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
Cui X, Yue Y, Li Z, Shi X, Qian C, Liu Z, Lin J
International journal of biological macromolecules 2025 Mar;297:139864
International journal of biological macromolecules 2025 Mar;297:139864
ROS scavenging and corneal epithelial wound healing by a self-crosslinked tissue-adhesive hydrogel based-on dual-functionalized hyaluronic acid.
Pan XY, Wang ZH, Wu XQ, Guo CR, Yang LX, Liu HR, Wang YH, Chen WJ, Wang JJ, Nan KH, Li LL
International journal of biological macromolecules 2025 Mar;293:139200
International journal of biological macromolecules 2025 Mar;293:139200
p16INK4a Deletion Alleviated Obesity-Associated Kidney Fibrosis by Regulating Metabolic Reprogramming and the Inflammasome Pathway.
Liu Q, Wang F, Du Y, Liu Y, Zhang Z, Zhang X, Li J, Huang G, Liu F, Li B, Xiao W, Sui C, Bao N, Zhuang R, Gao C, Wang X, Gu X
Journal of cellular and molecular medicine 2025 Mar;29(5):e70444
Journal of cellular and molecular medicine 2025 Mar;29(5):e70444
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Feng X, Ma Y, Zhao Y, Zhao Z, Song Z, Lin L, Wang W
Molecular immunology 2025 Mar;179:94-105
Molecular immunology 2025 Mar;179:94-105
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
Wang C, Li X, Ye T, Gu J, Zheng Z, Chen G, Dong J, Zhou W, Shi J, Zhang L
Bioorganic chemistry 2025 Mar;156:108170
Bioorganic chemistry 2025 Mar;156:108170
Citrulline regulates macrophage metabolism and inflammation to counter aging in mice.
Xie Z, Lin M, Xing B, Wang H, Zhang H, Cai Z, Mei X, Zhu ZJ
Science advances 2025 Mar 7;11(10):eads4957
Science advances 2025 Mar 7;11(10):eads4957
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
Deng L, Yu Q, Kuang G, Wang L, Fan J, Ye L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
Role of Adiponectin in Regulating Cytokines and Its Contribution to the Occurrence and Progression of Clinical Mastitis in Holstein Cows.
Zhang J, Chen N, Yang Z, Gao Y, Zhang B, Li J, Zhou B, Tang Z, Dong W, Zhao X, Zhang Y, Zhang Q
International journal of molecular sciences 2025 Mar 22;26(7)
International journal of molecular sciences 2025 Mar 22;26(7)
Resolvin D1 accelerates resolution of neuroinflammation by inhibiting microglia activation through the BDNF/TrkB signaling pathway.
Bo C, Liu X, Liu Y, Xu L, Huang Q
European journal of medical research 2025 Mar 20;30(1):189
European journal of medical research 2025 Mar 20;30(1):189
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Niu X, Chang G, Xu N, Li R, Niu B, Mao R, Wang S, Li G, Jiang J, Wang L
ACS nano 2025 Mar 18;19(10):10433-10451
ACS nano 2025 Mar 18;19(10):10433-10451
Nrf2 ameliorates defective autophagic processes and thereby inhibits ferroptosis in acute pancreatitis by suppressing Beclin1-Slc7a11 complex formation.
Li J, Jia YC, Zhang H, Wang Z, Ding Y, Cao F, Wang G, Li F
Free radical biology & medicine 2025 Mar 16;230:294-308
Free radical biology & medicine 2025 Mar 16;230:294-308
Medium- and long-chain triacylglycerols as enteral nutrition enhancing the nutritional status of postoperative rats undergoing chemotherapy by increasing the bioavailability of functional fatty acids.
Wang Y, Wei W, Wang Y, Liu X, Jin Q, Wang X
Food chemistry 2025 Mar 15;468:142410
Food chemistry 2025 Mar 15;468:142410
Lycopene inhibits doxorubicin-induced heart failure by inhibiting ferroptosis through the Nrf2 signaling pathway.
Huang R, Zhou C, Wang T, Chen Y, Xie Z, Wei L, Duan Y, Liao C, Ma C, Yang X
Life sciences 2025 Mar 15;365:123452
Life sciences 2025 Mar 15;365:123452
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages.
Qin X, Hu D, Li Q, Zhang S, Qin Z, Wang L, Liao R, Wu Z, Liu Y
Molecular medicine (Cambridge, Mass.) 2025 Mar 14;31(1):99
Molecular medicine (Cambridge, Mass.) 2025 Mar 14;31(1):99
Evaluation of anti-hyperuricemic and nephroprotective activities and discovery of new XOD inhibitors of Morus alba L. root bark.
Wang YA, Guo X, Zhang MQ, Sun ST, Ren QD, Wang MX, Wang LN, Farag MA, Sun JY, Liu C, Chen YY
Journal of ethnopharmacology 2025 Mar 13;343:119476
Journal of ethnopharmacology 2025 Mar 13;343:119476
Integration of single-cell RNA sequencing and network pharmacology to elucidate the effect of Yantiao Formula on alleviating ALI by regulating the polarization of alveolar macrophages.
Liu D, Zhang Y, Bai B, Xiong X, Zhou Q, Shi R
Journal of ethnopharmacology 2025 Mar 13;343:119436
Journal of ethnopharmacology 2025 Mar 13;343:119436
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
Wang F, Li J, Zhang Z, Huang G, Zhang X, Liu Q, Xiao W, Liu F, Sun J, Liu Y, Ma Y, Zhuang R, Du Y, Wang X, Gao C, Gu X
Tissue & cell 2025 Jun;94:102795
Tissue & cell 2025 Jun;94:102795
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Zhang M, Qiu H, Han Z, Ma Y, Hou J, Yuan J, Jia H, Zhou M, Lu H, Wu Y
International journal of pharmaceutics: X 2025 Jun;9:100316
International journal of pharmaceutics: X 2025 Jun;9:100316
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Glia 2025 Jun;73(6):1221-1240
Glia 2025 Jun;73(6):1221-1240
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
Ozkanlar S, Ozkanlar Y, Kara A, Dalkilinc E
Environmental toxicology 2025 Jun;40(6):924-934
Environmental toxicology 2025 Jun;40(6):924-934
Irisin Alleviates Impaired Mitochondrial Fusion via Enhancing PKA/SIRT3/mTOR Pathway in Hepatic Steatosis.
Li J, Zhao Y, Wang Z, Ma A, Ni Y, Wu D, Zhou Y, Zhang N, Zhang L, Chang Y, Wang Q
Journal of gastroenterology and hepatology 2025 Jun;40(6):1616-1630
Journal of gastroenterology and hepatology 2025 Jun;40(6):1616-1630
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Zhang X, Mao J, Li H, Zhang C, Ge H, Zhong J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Yan Y, Hu J, Han N, Li HT, Yang X, Li LG, Xu Z, Xia F, Li J, Li TF, Chen R
Materials today. Bio 2025 Jun;32:101848
Materials today. Bio 2025 Jun;32:101848
Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring.
Huang B, Zeng R, Liu X, Pan L, Bai H, Liao J, Xu W, Fu H, Nan K, Lin S
Materials today. Bio 2025 Jun;32:101722
Materials today. Bio 2025 Jun;32:101722
Polyvinyl alcohol/graphene oxide/dextran hydrogel doped copper oxide modified biochar with nano-enzymatic activity and multiple synergistic effects for accelerated diabetic wound healing.
Yang J, Ding C, Ding Q, Zhang S, Chai G, Wei H, Li D, Sui Q, Liu W, Liang D, Zhao T
International journal of biological macromolecules 2025 Jun;315(Pt 1):144480
International journal of biological macromolecules 2025 Jun;315(Pt 1):144480
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
Li Y, Fu Z, Deng C, Qian J, Wang Z, Lu Y, Zhang S, Liu G, Wen J, Chen Y, Jiang J, Liu X, Zheng X, Shen X, Su W, Yang M, Tang J, Wang Y, Meng B, Yang X
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
Dopaminergic Neuron-Derived AIMP1 Promotes Neurodegeneration via CD23-Dependent Microglial Activation.
Wang Q, Yu H, Yuan X, Li R, Li X, Yin S, Ma X, Wang X
CNS neuroscience & therapeutics 2025 Jun;31(6):e70472
CNS neuroscience & therapeutics 2025 Jun;31(6):e70472
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Targeted lipidomic reveals dietary LA/n-3 PUFAs regulate inflammation and redox status via oxylipins in bivalves.
Zhu Y, Liao K, Liu Y, Huang H, Zhang Y, Ge H, Chen D, Ma B, Xu J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159631
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159631
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Zhao T, Liu W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
LACC1 Enhances Polyamine Immunometabolism in Inflammatory Macrophages to Inhibit Atherosclerosis Progression.
Zhang J, Xu Y, Han Z, Liu B, Wang M, Bao L, He Y
Journal of cardiovascular translational research 2025 Jun;18(3):459-470
Journal of cardiovascular translational research 2025 Jun;18(3):459-470
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Pelargonidin-3-O-galactoside Alleviates Acute Lung Injury Induced by Klebsiella pneumoniae by Targeting CD38-Mediated Pyroptosis.
Jiang F, Jiang J, Sun Y, Meng L, Chen J, Liang L, Wang X, Zhang H, Meng M, Yuan B, He S, Li R
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13415-13426
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13415-13426
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Lu Y, Zhang L, Yang B, Hu H, Sun H, Guo D
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168
Journal of neuroinflammation 2025 Jun 28;22(1):168
Exosomal miR-574-3p from adipose-derived mesenchymal stem modulates CRIM1/BMPs signaling to restrain chondrocytes hypertrophy and inflammatory response in knee osteoarthritis.
Kang J, Zhang L, Zhang L, Nan N, Liu Y, Hao H
International immunopharmacology 2025 Jun 26;159:114916
International immunopharmacology 2025 Jun 26;159:114916
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway.
Yang H, Liu M, Song S, Xu Q, Lee J, Sun J, Xue S, Sun X, Che C
Investigative ophthalmology & visual science 2025 Jun 2;66(6):32
Investigative ophthalmology & visual science 2025 Jun 2;66(6):32
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Fan Z, Ye L, Wang S, Zhu Z, Wu C, Wu C, Kong L, Ning R
Neuromolecular medicine 2025 Jun 19;27(1):47
Neuromolecular medicine 2025 Jun 19;27(1):47
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
Fu G, Li T, Zhao Y, Zhang S, Xue X, Yang Y, Li T, Luo S, Yue G, Lei T
Chinese medicine 2025 Jun 16;20(1):87
Chinese medicine 2025 Jun 16;20(1):87
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
Xu Q, Zhang Z, Zhai Y, Chen J, Xu J, Chen H, Lu J
Brain research bulletin 2025 Jun 15;226:111385
Brain research bulletin 2025 Jun 15;226:111385
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia.
Lei X, Ran X, Wang J, Li L, Wu N, Ru X, Wang P, Li X, Li W, Huang Y
Life sciences 2025 Jun 1;370:123571
Life sciences 2025 Jun 1;370:123571
Spinal astrocyte-derived M-CSF mediates microglial reaction and drives visceral hypersensitivity following DSS-induced colitis.
Wu K, Shao S, Dong YT, Liu YY, Chen XH, Cheng P, Qin X, Peng XH, Zhang YM
Neuropharmacology 2025 Jun 1;270:110373
Neuropharmacology 2025 Jun 1;270:110373
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
Xu X, Shen Y, Wu J, Hong F, Xia H, Chen X, Lin G, Liu L, Xu RA
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Xie H, Tian S, Cui C, Sun C, Hu Y, Tang C, Gao D, Lu L, Jin L, Xu F, Lin J, Fu H, Liang X, Zhao L, Kong F, Wei X, Sun W, Li M, Li H
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
Yang R, Deng MY, Yang LK, Wang GZ, Ma J, Wen Q, Gao N, Qiao HL
Free radical biology & medicine 2025 Jul;234:220-232
Free radical biology & medicine 2025 Jul;234:220-232
Calcium Fructoborate Improves Knee Osteoarthritis in Rats by Activating Hedgehog Signaling Through DDIT3.
Yan T, Wang P, Cao Z
Biological trace element research 2025 Jul;203(7):3803-3819
Biological trace element research 2025 Jul;203(7):3803-3819
Diosmetin attenuates the ubiquitination of epidermal hypoxia-inducible factor 1 alpha by diminishing the formation of RhoBTB3/PHD2 complex in ultraviolet radiation-induced sunburn in mice.
Gong X, Yang S, Yuan Z, Zhang Z, Ali F, Zhang F, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156793
p38γ modulates ferroptosis in brain injury caused by ethanol and cerebral ischemia/reperfusion by regulating the p53/SLC7A11 signaling pathway.
Zhu X, Zhao Z, Zhang Y, Li H, Zhou X, Zhu Y, Chen Q, Kan S, Zhou L, Zhao G
Cellular signalling 2025 Jul;131:111728
Cellular signalling 2025 Jul;131:111728
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Wang Y, Zhang A, Chen Y, Qi D, Peng C, Liang Z, Guo J, Gu Y, Li H
Scientific reports 2025 Jul 7;15(1):24311
Scientific reports 2025 Jul 7;15(1):24311
Steroid constituents of Solidago canadensis alleviate LPS-induced inflammation via AMPK regulated mitophagy/NLRP3 and NF-κB pathway.
Yin W, Xue H, Zhang Y, Li R, Liu M, Yue H, Ge D, Liu N
European journal of pharmacology 2025 Jul 5;998:177512
European journal of pharmacology 2025 Jul 5;998:177512
The Rapid Activation of MYDGF Is Critical for Cell Survival in the Acute Phase of Retinal Regeneration in Fish.
Sugitani K, Omori Y, Mokuya T, Hosoi S, Kobayashi H, Miyata K, Araiso Y, Koriyama Y
International journal of molecular sciences 2025 Jul 27;26(15)
International journal of molecular sciences 2025 Jul 27;26(15)
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
Zhang XL, Jiang LL, Duan HT, Hu HY
Scientific reports 2025 Jul 27;15(1):27351
Scientific reports 2025 Jul 27;15(1):27351
Qifu Decoction Alleviates Lipopolysaccharide-Induced Myocardial Dysfunction by Inhibiting TLR4/NF-κB/NLRP3 Inflammatory Pathway and Activating PPARα/CPT Pathway.
Zhuo L, Ma M, Zhang J, Zhou J, Zheng Y, Liang A, Sun Q, Liu J, Liao W
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
18β-Glycyrrhetinic acid from Glycyrrhiza Uralensis protects colonic epithelium in ulcerative colitis by activating Wnt/β-catenin pathway to restore tight junction.
Peng X, Zhong R, Dong S, Qiu Y, Shu G, Huang S, Liu T, Yang Y, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156830
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156830
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Takahashi K, Nakagawasai O, Kurokawa K, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Gut microbiota-derived indoleacetic acid attenuates neuroinflammation and neurodegeneration in glaucoma through ahr/rage pathway.
Wang N, Sun C, Yang Y, Zhang D, Huang L, Xu C, Wang M, Xu M, Yan T, Wu Y, Xu L, Ju Y, Sun H, Guo W
Journal of neuroinflammation 2025 Jul 10;22(1):179
Journal of neuroinflammation 2025 Jul 10;22(1):179
Comparison of the effects of Liraglutide, Tirzepatide, and Retatrutide on diabetic kidney disease in db/db mice.
Ma J, Hu X, Zhang W, Tao M, Wang M, Lu W
Endocrine 2025 Jan;87(1):159-169
Endocrine 2025 Jan;87(1):159-169
A Novel Effect of Id2 in Microglia TNFα Regulation.
Wang W, Asiru, Luo G, Chen Y, Cui Y, Ping S, Chen Y
Molecular neurobiology 2025 Jan;62(1):304-321
Molecular neurobiology 2025 Jan;62(1):304-321
BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia.
Zhao W, Ma L, Deng D, Han L, Xu F, Zhang T, Wang Y, Huang S, Ding Y, Shu S, Chen X
Molecular neurobiology 2025 Jan;62(1):169-183
Molecular neurobiology 2025 Jan;62(1):169-183
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
Sun Z, Luan X, Sun Z, Li D, Hu H, Xue Q, Liu B, Yu Q, Wei G, Zhang X, Xi Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
Sini decoction alleviates inflammation injury after myocardial infarction through regulating arachidonic acid metabolism.
Long C, Zhou Q, Xu M, Ding X, Zhang X, Zhang Y, Tang Y, Tan G
Chinese herbal medicines 2025 Jan;17(1):148-155
Chinese herbal medicines 2025 Jan;17(1):148-155
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Tang J, Li X, Yu X, Wang D, Huang K, Pu H, Yu J, Li S, Wang W, Liu B, Guo S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
Shuhan W, Jinxiao L, Luorui S, Liuying C, Fangyuan Z, Mengqi Z, Qifeng L, Yuju C, Junli Z, Yao W, Shenglan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
Znhit1 alleviates nitroglycerin-induced hyperalgesia in migraine mice via the inhibition of NOD-like receptor signaling pathway.
Wang X, Tang J, Hou Y, Sui C
Molecular pain 2025 Jan-Dec;21:17448069251389420
Molecular pain 2025 Jan-Dec;21:17448069251389420
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Yang S, Duan H, Yan Z, Xue C, Niu T, Cheng W, Zhang Y, Zhao X, Hu J, Zhang L
Nutrients 2025 Jan 7;17(2)
Nutrients 2025 Jan 7;17(2)
Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.
Liu Y, Li T, Niu C, Yuan Z, Sun S, Liu D
Molecular medicine (Cambridge, Mass.) 2025 Jan 3;31(1):1
Molecular medicine (Cambridge, Mass.) 2025 Jan 3;31(1):1
The injury effect of osteopontin in sepsis-associated lung injury.
Wang Q, Yu Z, Song Z, Lu X, Li Z, Pi D, Li J, Xu F
Journal of inflammation (London, England) 2025 Jan 24;22(1):4
Journal of inflammation (London, England) 2025 Jan 24;22(1):4
Engineered Therapeutic Bacteria with High-Yield Membrane Vesicle Production Inspired by Eukaryotic Membrane Curvature for Treating Inflammatory Bowel Disease.
Chen J, Liu M, Chen S, Chou CP, Liu H, Wu D, Liu Y
ACS nano 2025 Jan 21;19(2):2405-2418
ACS nano 2025 Jan 21;19(2):2405-2418
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Zhang H, Zhang Y, Zhang Y, Wei H, Jin S, Huo T, Qin L
Food & function 2025 Jan 20;16(2):673-690
Food & function 2025 Jan 20;16(2):673-690
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Zhu J, Zhang Y, Sun Y, Yu F, Lu Y, Hu Q, Guo J, Zhang H, Chen T, Lian F, Wang J, Li X, Xiao J
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis.
Xia B, Lu YL, Peng J, Liang JW, Li FQ, Ding JY, Wan CW, Le CY, Dai JL, Jie-Wang, Guo B, Huang J
Scientific reports 2025 Jan 2;15(1):603
Scientific reports 2025 Jan 2;15(1):603
The Ku protein family regulates hyperglycemia-induced vascular endothelial cell inflammation by modulating P300 levels.
Cai Q, Zhao Q, Yang Q, Zhu M, Meng F, Jiang J
Experimental cell research 2025 Jan 15;444(2):114399
Experimental cell research 2025 Jan 15;444(2):114399
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
Xiong Z, Kong Q, Hua J, Chen Q, Wang D
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy.
Jiang F, Tang J, Wei X, Pan H, Fan X, Zhang P, Guo S
Chinese medicine 2025 Jan 15;20(1):12
Chinese medicine 2025 Jan 15;20(1):12
Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson's disease model mice.
Song W, Zhou ZM, Zhang LL, Shu HF, Xia JR, Qin X, Hua R, Zhang YM
Cell death & disease 2025 Jan 14;16(1):18
Cell death & disease 2025 Jan 14;16(1):18
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Yang S, Duan H, Zeng J, Yan Z, Niu T, Ma X, Zhang Y, Hu J, Zhang L, Zhao X
Journal of ethnopharmacology 2025 Jan 13;339:119157
Journal of ethnopharmacology 2025 Jan 13;339:119157
Uncovering the mechanisms of Zhubi decoction against rheumatoid arthritis through an integrated study of network pharmacology, metabolomics, and intestinal flora.
Liu J, Li B, Zhou X, Liu G, Li C, Hu Z, Peng R
Journal of ethnopharmacology 2025 Jan 10;336:118736
Journal of ethnopharmacology 2025 Jan 10;336:118736
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis.
Wang S, Huang Z, Nie S, Chen Y, Lei Y, Tu W, Luo M, Zhang ZG, Tian DA, Gong J, Liu M
International immunopharmacology 2025 Jan 10;144:113712
International immunopharmacology 2025 Jan 10;144:113712
TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway.
Tang S, Xing W, Yan J, Wang L, Li Z, Wang Y, Gu N, Sun X
Brain research 2025 Jan 1;1846:149235
Brain research 2025 Jan 1;1846:149235
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway.
Kuang G, Zhao Y, Wang L, Wen T, Liu P, Ma B, Peng Q, Xu F, Ye L, Fan J
Phytotherapy research : PTR 2025 Feb;39(2):733-746
Phytotherapy research : PTR 2025 Feb;39(2):733-746
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
Wang C, Li S, Li Q, Xi H, Li J, Zhu Q, Wu P, Zhu YZ, Mao Y
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Xu J, Gu H, Zhou K, Wu L, Zhang Y, Bian C, Huang Z, Chen G, Cheng X, Yin X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse.
Cheng SY, Yang YF, Wang YL, Yue ZP, Chen YZ, Wang WK, Xu ZR, Li LF, Shen H, Qi ZM, Xu CL, Liu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115201
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115201
Neohesperidin protects against colitis-associated colorectal cancer in mice via suppression of the NF-κB/p65 and MAPK pathways.
Cao X, Li L, Hu J, Zhu S, Song S, Kong S, Zhou L, Huang Y
The Journal of nutritional biochemistry 2025 Feb;136:109804
The Journal of nutritional biochemistry 2025 Feb;136:109804
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
He X, Deng B, Zhang C, Zhang G, Yang F, Zhu D, Yang Y, Ma B, Hu X, Wang Y, Kang X
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway.
Wang C, Li YZ, Guo H, Zhou SR, Peng X, Wang JS, Xie HT, Zhang MC
Investigative ophthalmology & visual science 2025 Feb 3;66(2):51
Investigative ophthalmology & visual science 2025 Feb 3;66(2):51
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
Li G, Huang L, Gu D, Wang P, Yi L, Kuang W, Zhang Y, Zhang J, Liu D, Shi Q, Tang H, Sun J, Zeng G, Peng X, Wang J
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
Huangqi-Danshen decoction alleviates renal fibrosis through targeting SCD1 to modulate cGAS/STING signaling.
Peng Y, Wu S, Xu Y, Ye X, Huang X, Gao L, Lu J, Liu X
Journal of ethnopharmacology 2025 Feb 27;342:119364
Journal of ethnopharmacology 2025 Feb 27;342:119364
Multifunctional Injectable Bioadhesive with Toll-like Receptor 4 and Myeloid Differentiation Factor 2 Antagonistic Anti-inflammatory Potential for Periodontal Regeneration.
Gao S, Li H, Li Z, Wang H, Li X, Yang S, Huang L, Zhang B, Zhang K, Tsoi JKH, He J, Dissanayaka WL
ACS nano 2025 Feb 25;19(7):7098-7116
ACS nano 2025 Feb 25;19(7):7098-7116
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Wang Y, Ding H, Bai R, Li Q, Ren B, Lin P, Li C, Chen M, Xu X
Stem cell research & therapy 2025 Feb 21;16(1):80
Stem cell research & therapy 2025 Feb 21;16(1):80
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Meng X, Li Y, Meng L, Yang C, Xia C, Wang X, Wang F
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
Circular RNA APP contributes to Alzheimer's disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis.
Wu DP, Wei YS, Hou LX, Du YX, Yan QQ, Liu LL, Zhao YD, Yan RY, Yu C, Zhong ZG, Huang JL
Alzheimer's research & therapy 2025 Feb 14;17(1):44
Alzheimer's research & therapy 2025 Feb 14;17(1):44
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses.
Li P, Zhang R, Hu P, Wang T, Wang J
Journal of ethnopharmacology 2025 Feb 11;341:119358
Journal of ethnopharmacology 2025 Feb 11;341:119358
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
Wu X, Wang Y, Liu X, Ding Q, Zhang S, Wang Y, Chai G, Tang Y, Yang J, Yu T, Liu W, Ding C
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Deng D, Ma L, Shen J, Huang L, Zhang T, Yang X, Huang S, Zhao W, Zhou Y, Fan S, Wang K, Chen X
Molecular neurobiology 2025 Dec;62(12):15478-15493
Molecular neurobiology 2025 Dec;62(12):15478-15493
Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection.
Chao R, Wang Y, Liu Z, Wan T, Mao Y, Xie X, Sun L, Xu W, Chen X, Zhang S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
Gao H, Luo J, Chen X, Huang Y, Mo M, Luo Q, Liu Y, Zou B, Lei Y, Li Z, Huang L, Huang X, Liang P, Lin M, Huang J, Lu H, Huang H, Gao H, Zhang J, Lu J, Gao M
Bioactive materials 2025 Dec;54:759-776
Bioactive materials 2025 Dec;54:759-776
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
Ni F, Chang L, Peng Y, Li D, Wu D, Li K, Zhang X, Jiang X, Shao Z, Chen Y, Wang H
Bioactive materials 2025 Dec;54:248-272
Bioactive materials 2025 Dec;54:248-272
RUNX1 Induces Central Neuropathic Pain by Activating Microglia and Triggering the Inflammatory Response in Spinal Cord Injury.
Huang M, Yang Y, Tang Y, Li Y, Wang X, Zhou M
Inflammation 2025 Dec;48(6):4443-4460
Inflammation 2025 Dec;48(6):4443-4460
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351
Biochemistry and biophysics reports 2025 Dec;44:102351
Inhibition of 12/15-LOX hyperactivation mitigates cognitive decline in a chronic cerebral hypoperfusion mouse model and in H(2)O(2)-induced HT22 cells: therapeutic effects of brozopine.
Wang X, Lu Z, Shao Q, Wang Y, Zhang Z, Wang Z, Jia Q, Zhu J, Song Y, Yuan L, Wang Y, Xu S, He L, Chang J, Gao Y
Journal of enzyme inhibition and medicinal chemistry 2025 Dec;40(1):2547259
Journal of enzyme inhibition and medicinal chemistry 2025 Dec;40(1):2547259
Photothermal-triggered NO-releasing nanofiber membrane mitigates intervertebral disc degeneration via inflammation inhibition and matrix stabilization.
Huang G, Xie J, Chen J, Zhao J, Wang P, Zhang J, Xu P, Li Y, Chen X, Miao X, Xiong W, Cheng X
Materials today. Bio 2025 Dec;35:102287
Materials today. Bio 2025 Dec;35:102287
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Ni Y, Jiang X, Wang S, Pu T, Yan T, Yu A, Liu Q
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Hyperhomocysteinaemia aggravates periodontitis by suppressing the Nrf2/HO-1 signalling pathway.
Yang K, Yang Y, Long T, Wang X, Chen Y, He C, Li L, Yang X, Jiang M, Hu Y, Dai F, Song L
Redox report : communications in free radical research 2025 Dec;30(1):2475691
Redox report : communications in free radical research 2025 Dec;30(1):2475691
Intranasal LAG3 antibody infusion induces microglia-dependent antidepressant effect by mobilizing astrocytic P2Y1R-mediated BDNF synthesis in the hippocampus.
Hu W, Ye M, Dai Q, Sun M, Song R, Lu X, Huang C, Zhang L, Yang R
Pharmacology, biochemistry, and behavior 2025 Dec;257:174114
Pharmacology, biochemistry, and behavior 2025 Dec;257:174114
The multifaceted modulations by dapagliflozin in preventing hyperglycemia-induced diabetic nephropathy through glucose transporters and PPARα.
Chung HH, Tseng CJ, Cheng PW
Journal of diabetes and metabolic disorders 2025 Dec;24(2):154
Journal of diabetes and metabolic disorders 2025 Dec;24(2):154
Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation.
Deng Z, Mei S, Ouyang Z, Wang R, Wang L, Zou B, Dai J, Mao K, Li Q, Guo Q, Yi C, Meng F, Xie M, Zhang X, Wang R, Deng T, Wang Z, Li X, Wang Q, Liu B, Tian X
Gut microbes 2025 Dec;17(1):2476561
Gut microbes 2025 Dec;17(1):2476561
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Deng Y, Jiang X, Che Z, Shang Y, Hu M, Wang W, Yu W, Yang B, Liu X
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Comparative evaluation of the therapeutic efficacy between human amniotic epithelial cells and human umbilical cord mesenchymal stem cells in premature ovarian insufficiency.
Zhang Q, Wang J, Cheng Z, Cao W, Zhang Q, Lai D
Stem cell research & therapy 2025 Dec 31;17(1):65
Stem cell research & therapy 2025 Dec 31;17(1):65
Structural polysaccharide PCP1 from Polygonatum cyrtonema Hua attenuates atherosclerosis via dual-target suppression of CD36/MSR1 and TLR4/NF-κB pathways.
Zhou L, Zhao X, Yang Z, Jiang C, Song H, Liu W, Wang G, Che H, Han J
International immunopharmacology 2025 Dec 3;166:115644
International immunopharmacology 2025 Dec 3;166:115644
Brevilin A reverses colitis of inflammatory bowel disease via modulation of TNF-α signaling and microbiome dysregulation.
Chen L, Tang C, Hu D, Yu S, Liao P
Gut pathogens 2025 Dec 29;18(1):1
Gut pathogens 2025 Dec 29;18(1):1
Reactive oxygen species-associated molecular landscape uncovers diagnostic and immune features in osteoarthritis.
Zhou J, Qiu P, Liang T, Xue B
Journal of orthopaedic surgery and research 2025 Dec 25;21(1):51
Journal of orthopaedic surgery and research 2025 Dec 25;21(1):51
Mitochondrial-Targeting Drug-Loaded Nanoparticles Reprogram Macrophage Metabolism via ROS/NO Co-elimination for Diabetic Wound Healing.
Zhou X, Huang Z, Yang H, Jin L, Zhang Y
ACS applied materials & interfaces 2025 Dec 24;17(51):69180-69195
ACS applied materials & interfaces 2025 Dec 24;17(51):69180-69195
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Zhao C, Liu J, Zhao S, Liu P, Li Z, Li Y, Dong R, Wang XL
Physiological research 2025 Dec 2;74(5):871-884
Physiological research 2025 Dec 2;74(5):871-884
MXene-integrated microneedles reprogram diabetic-associated macrophages for deep-wound infection therapy and immunoprotection.
Li W, Wang L, Zhao H, Zhang R, Zhang Y, Lin S, Qin H, Zong X, Gan K, Wang J, Yin H, Chen Y, Li R
Journal of nanobiotechnology 2025 Dec 2;24(1):12
Journal of nanobiotechnology 2025 Dec 2;24(1):12
Synthesis, antibacterial activity, and mechanistic characterization of novel 9-substituted berberine derivatives.
Tong J, Yang H, He Y, Chen K, Chen C, Han H, Li C
RSC medicinal chemistry 2025 Dec 2;17(2):951-64
RSC medicinal chemistry 2025 Dec 2;17(2):951-64
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Zhang P, Wang X, Lu N, Nie Y, Zhang X, Liu L
iScience 2025 Dec 19;28(12):113982
iScience 2025 Dec 19;28(12):113982
Ectopic engraftment of nociceptive neurons derived from hPSCs for pain relief and joint homeostasis.
Wang Z, Zhang W, Wang J, Wu Z, Cao X, Peng J, Lee G, Dong X
bioRxiv : the preprint server for biology 2025 Dec 19;
bioRxiv : the preprint server for biology 2025 Dec 19;
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
Guo H, Guo T, Wang X, Bao Y, Zhang Z, Xue F, Cheng D
BMC geriatrics 2025 Dec 12;26(1):69
BMC geriatrics 2025 Dec 12;26(1):69
Nebulized M2 macrophage-derived nanovesicles for the treatment of explosion-induced acute lung injury.
Tian L, Jin J, Lai F, Yao S, Zhang Y, Liu J, Zhang H, Lu Q, Liu C, Tian S, Lu Y, Liang Y, Zhao Y, Fan H, Ren W
Journal of colloid and interface science 2025 Aug;691:137381
Journal of colloid and interface science 2025 Aug;691:137381
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
Wang M, Huang X, Shu J, Li H, Yang T, Li N, Yang P
Inflammation 2025 Aug;48(4):1716-1727
Inflammation 2025 Aug;48(4):1716-1727
Danggui Buxue Decoction Combined with Borneol Improves Cyclophosphamide-Induced Myelosuppression by Inhibiting CDK2.
Li K, Wu R, Zhou T, Xiong J
Cancer biotherapy & radiopharmaceuticals 2025 Aug;40(6):426-440
Cancer biotherapy & radiopharmaceuticals 2025 Aug;40(6):426-440
Exosomal tpi-miR-10a-5p from T. pisiformis cysticerci regulates the expression of inflammatory factors in rabbits by targeting MAP3K7.
Pu G, Wang L, Liu T, Wang D, Li H, Amuda TO, Yin H, Yan H, Zhang X, Luo X
Veterinary parasitology 2025 Aug;338:110537
Veterinary parasitology 2025 Aug;338:110537
Curcumin-alendronate carbon dots: A dual-logic strategy for precision treatment of periodontitis.
Zhang S, Zhang X, Huang J, Zhou N, Zhang F, Ren J, Zhang W, Wang T, Xu W, Luan X, Huang X, Huang Z, Wu J, Da J, Liu L, Zhang B, Li Y, Jin H
Materials today. Bio 2025 Aug;33:102073
Materials today. Bio 2025 Aug;33:102073
Deliver CEBPE via cartilage targeting Lipid nanoparticle to block CEBPE-LTF-STAT3 positive feedback loop for efficient treatment of cartilage endplate degeneration.
Zhao J, Xu P, Li T, Yuan J, Zhao W, Ding R, Yang G, Xie J, Huang G, Peng Z, Miao X, Cheng X
Materials today. Bio 2025 Aug;33:102027
Materials today. Bio 2025 Aug;33:102027
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
Zhu C, Huang K, Li T, Li Y, Jin Y, Li R, Zhu Z, Yang S, Xia L, Fang B
Biomaterials 2025 Aug;319:123179
Biomaterials 2025 Aug;319:123179
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2025 Aug;21(4):675-685
Purinergic signalling 2025 Aug;21(4):675-685
Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Combined with PEG Hydrogel Alleviate Maternal Simulated Birth Injury in a Rat Model.
Wang Q, Li Y, Zhang Y, Wu X, Wang S, Sun X, Wang J
Advanced healthcare materials 2025 Aug;14(20):e2405259
Advanced healthcare materials 2025 Aug;14(20):e2405259
Stimulation of microglia leads to a rapid antidepressant effect by triggering astrocytic P2Y1Rs and promoting BDNF-mediated neurogenesis in the hippocampus.
Wang H, Lu X, Ye Y, Huang C, Fang Y, Yang R, Sun M, Ren J, Song R, Xu F, Su J, Hong H, Huang C
Brain, behavior, and immunity 2025 Aug;128:134-151
Brain, behavior, and immunity 2025 Aug;128:134-151
Discovery of a CYP2E1 inhibitor and its therapeutic potential in severe acute pancreatitis.
Qiu J, Lu J, Wang X, Zhang Y, Guo M, Guo F, Xu H, Qiao H
European journal of medicinal chemistry 2025 Aug 5;292:117666
European journal of medicinal chemistry 2025 Aug 5;292:117666
Rehmannioside A alleviates renal inflammation and fibrosis in hypertensive nephropathy via AT1R/MAPK14/IL-17 signaling pathway.
Liu F, Wang J, Sun Z, Yu X
Biochemical and biophysical research communications 2025 Aug 30;776:152237
Biochemical and biophysical research communications 2025 Aug 30;776:152237
Dihydroartemisinin restrains angiogenesis through the TNF-α pathway to enhance the efficacy of anti-PD-1 immunotherapy in breast cancer.
Zou M, Gong Y, Zeng J, Zhang X, Guo X, Hua J, Chen Z, Lin L, Wu F
Biochemical and biophysical research communications 2025 Aug 30;776:152171
Biochemical and biophysical research communications 2025 Aug 30;776:152171
Methamphetamine Exposure Induces Neuronal Programmed Necrosis by Permeabilizing Mitochondria via the RIPK1-RIPK3-MLKL Axis.
Zhou P, Xuan J, Xu W, An D, Meng S, Zhang H, Hu M, Hui W, Wang Y, Cheng J, Xiong J, Wang J, Chen X
Toxics 2025 Aug 30;13(9)
Toxics 2025 Aug 30;13(9)
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Ma DY, Peng LF, Gao XY, Xing TJ, Hao ZH
Journal of ethnopharmacology 2025 Aug 29;352:120172
Journal of ethnopharmacology 2025 Aug 29;352:120172
Baicalin Alleviates ADAM17/EGFR Axis-Induced Peritonitis in Weaned Piglets Infected by Glaesserella parasuis.
Lu Q, Liu X, Tian J, Guo P, Ye C, Fu S, Liu Y, Qiu Y
Animals : an open access journal from MDPI 2025 Aug 21;15(16)
Animals : an open access journal from MDPI 2025 Aug 21;15(16)
Inhibition of ADAM17: A New Therapeutic Strategy to Alleviate Zearalenone Toxin-Induced Liver Injury by Endoplasmic Reticulum Stress and Inflammation.
Liu P, Gu Y, Xu Z, Zou H, Gu J, Yuan Y, Liu Z, Bian J
Journal of agricultural and food chemistry 2025 Aug 20;73(33):21120-21132
Journal of agricultural and food chemistry 2025 Aug 20;73(33):21120-21132
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
Li N, Liu X, Wang Q, Chen Y, Han C, Qu C, Guan X, Zou W, Wang X, Li A, Zhang Y, Zhu L, Du R, Liu J, Wang Y
Stem cell research & therapy 2025 Aug 2;16(1):419
Stem cell research & therapy 2025 Aug 2;16(1):419
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
Lan Q, Liufu S, Chen B, Wang K, Chen W, Xiao L, Liu X, Yi L, Liu J, Xu X, Liu C, Liu M, Yin Y, Ma H
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
NOD2 promotes sepsis-induced neuroinflammation by increasing brain endoplasmic reticulum stress mediated by LACC1.
Yi L, Chen Z, Zhou Q, Liu N, Li Q, Wu X, Zeng Y, Lin Y, Lin S, Luo L, Jiang S, Huang P, Wang H, Deng Y
Free radical biology & medicine 2025 Aug 1;235:280-293
Free radical biology & medicine 2025 Aug 1;235:280-293
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula.
Zhang R, Li W, Yang J, Fan X, Fan H, Li W
Advanced biology 2025 Apr;9(4):e2400437
Advanced biology 2025 Apr;9(4):e2400437
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Yang Q, Yang C, Lv H, Zheng X, Mao S, Liu N, Mo S, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Shang J
Inflammation 2025 Apr;48(2):541-556
Inflammation 2025 Apr;48(2):541-556
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
Xiao C, Li Q, Li M, Han Y, Xu H, Jiang H, Zhang S, Jin Z, Gao L
Toxicology letters 2025 Apr;406:9-19
Toxicology letters 2025 Apr;406:9-19
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Zhang Y, Lou Q, Lian H, Yang R, Cui R, Wang L, Ma B, Hou L, Jin L, Teng W
Materials today. Bio 2025 Apr;31:101589
Materials today. Bio 2025 Apr;31:101589
CEBPA as a potential hub gene for cutaneous inflammation in type 2 diabetes mellitus.
Han M, Wang J, Wu Y, Liao J, Guo J, Tang Z
International journal of biological macromolecules 2025 Apr;298:140080
International journal of biological macromolecules 2025 Apr;298:140080
Pinocembrin alleviates renal ischemia-reperfusion injury/unilateral ureteral obstruction (UUO)-generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis.
Zhang BH, Chen H, Yang R, Jiang Z, Huang S, Chen Z, Liu C, Wang L, Liu XH
The FEBS journal 2025 Apr;292(8):2119-2144
The FEBS journal 2025 Apr;292(8):2119-2144
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Mao Z, Lin X, Hu Y, Liu Y, Yu S, Zhou T, Zhang J, Yang X, Tian S, Miao M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.
Yang T, Fang B, Chen Y, Bao D, Zhang J, Liu P, Duan Z, He Y, Zhao X, Zhang QW, Dong WT, Zhang Y
Biomolecules 2025 Apr 7;15(4)
Biomolecules 2025 Apr 7;15(4)
Sensitivity of Various Indicators in a Mouse Sensitive Skin Model Treatment with 4-tert-Butylcyclohexanol and Pimecrolimus.
Tang X, Wang X, Zhang Y, Chen Q, Zhao S, Xu X, Yang X, Liu X, Zhang L, Zhang M
International journal of molecular sciences 2025 Apr 25;26(9)
International journal of molecular sciences 2025 Apr 25;26(9)
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Apr 17;17(1):30
International journal of oral science 2025 Apr 17;17(1):30
Oleanolic acid inhibits mesangial cell proliferation and inflammatory response in mesangial proliferative glomerulonephritis through IL-17/ERK/AKT pathway.
Pan D, Xia J, Qu Y, Shi C, Du H, Zhang J, Peng F, Wang X, Liu R, Wu L, Hong Q, Chen X
International immunopharmacology 2025 Apr 16;152:114459
International immunopharmacology 2025 Apr 16;152:114459
Jatrorrhizine retard obesity by modulating transcription factor c-Jun/c-Fos to downregulate Mmp12-mediated inflammation.
Ma Z, Li J, Zhu J, Yang Z, Li X, Wang H, Tang Q, Zhou Y, Manzoor R, Chen X, Ma H, Ye X
International immunopharmacology 2025 Apr 16;152:114405
International immunopharmacology 2025 Apr 16;152:114405
Anethole trithione mitigates LPS/D-Gal-induced acute liver injury by suppressing ROS production and NF-κB activity.
He Z, Tan X, Yuan M, Chen L, Meng Y, Wang Q, Hu J, Qiu Z, Yang Y
International immunopharmacology 2025 Apr 16;152:114371
International immunopharmacology 2025 Apr 16;152:114371
Inhibition of Zbp1-PANoptosome-mediated PANoptosis effectively attenuates acute pancreatitis.
Li J, Jia YC, Lu J, Zhang H, Wang Z, Xie X, Cao F, Li F
Cell death discovery 2025 Apr 16;11(1):180
Cell death discovery 2025 Apr 16;11(1):180
The Potential of Siraitia grosvenorii to Promote Bone Regeneration via Modulating Macrophage Polarization: A Network Pharmacology and Experimental Study.
Mai Y, Huang L, Qiao Y, Qin Y, Wang L, Liao H
International journal of molecular sciences 2025 Apr 11;26(8)
International journal of molecular sciences 2025 Apr 11;26(8)
Vitamin D(3) alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats.
Ke B, Li C, Li S, Yan J, Sun L
Turkish journal of medical sciences 2024;54(5):1165-1174
Turkish journal of medical sciences 2024;54(5):1165-1174
Exploring the Action Mechanism and Validation of the Key Pathways of Dendrobium officinale Throat-clearing Formula for the Treatment of Chronic Pharyngitis Based on Network Pharmacology.
Fang X, Jiang XF, Zhang YP, Zhou CL, Dong YJ, Bo-Li, Lv GY, Chen SH
Combinatorial chemistry & high throughput screening 2024;27(3):479-496
Combinatorial chemistry & high throughput screening 2024;27(3):479-496
Mechanistic study of celastrol-mediated inhibition of proinflammatory activation of macrophages in IgA nephropathy via down-regulating ECM1.
Zhao J, Liu H, Chen Q, Xia M, Wan L, Yu W, Liu C, Hao X, Tang C, Chen G, Liu Y, Yuan F, Liu H
International journal of biological sciences 2024;20(14):5731-5746
International journal of biological sciences 2024;20(14):5731-5746
Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target.
Lin L, Huang S, Lin X, Liu X, Xu X, Li C, Chen P
PloS one 2024;19(8):e0309338
PloS one 2024;19(8):e0309338
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Wang Y, Deng X, Wei J, Yang Z, Du Y, Song S, Shi Y, Wu H
PloS one 2024;19(6):e0299389
PloS one 2024;19(6):e0299389
Exploring the effects of hypoxia and reoxygenation time on hepatocyte apoptosis and inflammation.
Xu X, Zhou T, Tulahong A, Ruze R, Shao Y
PloS one 2024;19(11):e0310535
PloS one 2024;19(11):e0310535
Exercise Attenuate Diaphragm Atrophy in COPD Mice via Inhibiting the RhoA/ROCK Signaling.
Li P, Wang Y, Cao Y, Shi J, Jiang M, Han X, Jiang L, Bao Y, Wu W, Liu X
International journal of chronic obstructive pulmonary disease 2024;19:1591-1601
International journal of chronic obstructive pulmonary disease 2024;19:1591-1601
Angiotensin-(1-7) Modulates the Warburg Effect to Alleviate Inflammation in LPS-Induced Macrophages and Septic Mice.
Yu D, Huang W, Sheng M, Zhang S, Pan H, Ren F, Luo L, Zhou J, Huang D, Tang L
Journal of inflammation research 2024;17:469-485
Journal of inflammation research 2024;17:469-485
Exercise preconditioning and resveratrol reduce the susceptibility of rats with obstructive jaundice to endotoxin and alleviate lung injury.
Li X, Li W, Wang T, Li Y, Zhao L
Frontiers in immunology 2024;15:1466615
Frontiers in immunology 2024;15:1466615
Rosa roxburghii fermented juice mitigates LPS-induced acute lung injury by modulation of intestinal flora and metabolites.
Chen Z, Zhang S, Sun X, Meng D, Lai C, Zhang M, Wang P, Huang X, Gao X
Frontiers in microbiology 2024;15:1447735
Frontiers in microbiology 2024;15:1447735
Vagal innervation limits brain injury by inhibiting gut-selective integrin-mediated intestinal immunocyte migration in intracerebral hemorrhage.
Fu P, Zong Y, Dai Y, Zhu L, Chen S, Rastegar-Kashkooli Y, Wang J, Zhang J, Wang J, Jiang C
Theranostics 2024;14(19):7383-7404
Theranostics 2024;14(19):7383-7404
Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.
Chen L, Zhang M, Yang X, Wang Y, Huang T, Li X, Ban Y, Li Q, Yang Q, Zhang Y, Zheng Y, Wang D, Wang X, Shi X, Zhang M, Sun Y, Wu J
Theranostics 2024;14(11):4256-4277
Theranostics 2024;14(11):4256-4277
Antibacterial and antioxidant phlorizin-loaded nanofiber film effectively promotes the healing of burn wounds.
Yang Y, Ma S, Li A, Xia G, Li M, Ding C, Sun X, Yan L, Yang M, Zhao T
Frontiers in bioengineering and biotechnology 2024;12:1428988
Frontiers in bioengineering and biotechnology 2024;12:1428988
TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses.
Sawoo R, Bishayi B
Immunobiology 2024 Sep;229(5):152840
Immunobiology 2024 Sep;229(5):152840
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
Dong H, Song H, Liu Y, Zou H
Biological trace element research 2024 Sep;202(9):4203-4215
Biological trace element research 2024 Sep;202(9):4203-4215
Polystyrene microplastics facilitate renal fibrosis through accelerating tubular epithelial cell senescence.
Pan C, Wang X, Fan Z, Mao W, Shi Y, Wu Y, Liu T, Xu Z, Wang H, Chen H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Sep;191:114888
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Sep;191:114888
Schisandrol B inhibits calcification of aortic valve by targeting p53 related inflammatory and senescence.
Liu X, Wang K, Zheng Q, Liu X, Yang Y, Xie C, Yao D, Jiang C, Liu Z, Li H, Shi J, Dong N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117241
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117241
5-aminolevulinic acid photodynamic therapy for chronic wound infection in rats with diabetes.
Guo N, Chen J, Kong F, Gao Y, Bian J, Liu T, Hong G, Zhao Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117132
Red nucleus mGluR1 and mGluR5 facilitate the development of neuropathic pain through stimulating the expressions of TNF-α and IL-1β.
Tian X, Wang WT, Zhang MM, Yang QQ, Xu YL, Wu JB, Xie XX, Wang JY, Wang JY
Neurochemistry international 2024 Sep;178:105786
Neurochemistry international 2024 Sep;178:105786
Artemisia argyi polyphenols Attenuates DSS-induced colitis in mice by regulating the structural composition of gut microbiota.
Zhang H, Hao Z, Zhang R, Tong J, Wang X, Liu J, Gao Y, Wang X, Su Q, Wen H, Fan Y, Liu F, Li X, Tong C, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155897
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155897
Intermittent Fasting Targets Osteocyte Neuropeptide Y to Relieve Osteoarthritis.
Qian YX, Rao SS, Tan YJ, Wang Z, Yin H, Wan TF, He ZH, Wang X, Hong CG, Zeng HJ, Luo Y, Duan YX, Zhu H, Hu XY, Zou L, Zhang Y, Liu BB, Wang ZX, Du W, Chen CY, Xie H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(34):e2400196
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(34):e2400196
Wenshenqianlie capsule improves benign prostatic hyperplasia via its anti-inflammatory and antioxidant effects.
Liu R, Sun Z, Wang S, Liu X, Man Y, Chen M, Liu Q, Wang C
Aging 2024 Sep 4;16(18):12574-12592
Aging 2024 Sep 4;16(18):12574-12592
Palmatine ameliorates N-methyl-N'-nitrosoguanidine-induced chronic atrophic gastritis through the STAT1/CXCL10 axis.
Zhou Y, Wang Q, Tang W, Ma Z, Yang Z, Li X, Chen W, Ma H, Ye X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70037
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70037
Vagus nerve stimulation (VNS) inhibits cardiac mast cells activation and improves myocardial atrophy after ischemic stroke.
Tan Q, Ruan Y, Wu S, Jiang Y, Fu R, Gu X, Yu J, Wu Q, Li M, Jiang S
International immunopharmacology 2024 Sep 30;139:112714
International immunopharmacology 2024 Sep 30;139:112714
The senescent marker p16INK4a enhances macrophage foam cells formation.
Siew WS, Tang YQ, Goh BH, Yap WH
Molecular biology reports 2024 Sep 27;51(1):1021
Molecular biology reports 2024 Sep 27;51(1):1021
Exploring the efficacy and mechanism of Bailing capsule to improve polycystic ovary syndrome in mice based on intestinal-derived LPS-TLR4 pathway.
Guan HR, Li B, Zhang ZH, Wu HS, Wang N, Chen XF, Zhou CL, Bian XR, Li L, Xu WF, He XL, Dong YJ, Jiang NH, Su J, Lv GY, Chen SH
Journal of ethnopharmacology 2024 Sep 15;331:118274
Journal of ethnopharmacology 2024 Sep 15;331:118274
Construction of a mouse model for sensitive skin research.
Huang B, Wang X, Bu L, Zhang Y, Liu X, Liang F, Zhang X, Tang X, Wu S, Huang J, Zhang L, Zhang M
Contact dermatitis 2024 Oct;91(4):327-341
Contact dermatitis 2024 Oct;91(4):327-341
Dual-Drug Nanomedicine Assembly with Synergistic Anti-Aneurysmal Effects via Inflammation Suppression and Extracellular Matrix Stabilization.
Zu HL, Zhuang PP, Peng Y, Peng C, Peng C, Zhu ZJ, Yao Y, Yue J, Wang QS, Zhou WH, Wang HY
Small (Weinheim an der Bergstrasse, Germany) 2024 Oct;20(43):e2402141
Small (Weinheim an der Bergstrasse, Germany) 2024 Oct;20(43):e2402141
Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-α and IL-1β.
Wang WT, Feng F, Zhang MM, Tian X, Yang QQ, Li YJ, Tao XX, Xu YL, Dou E, Wang JY, Zeng XY
Neurochemistry international 2024 Oct;179:105840
Neurochemistry international 2024 Oct;179:105840
Prolonged exposure to a music-enriched environment mitigates acute noise-induced inflammation and apoptosis in the chicken spleen by modulating the Keap-1/Nrf2 and NF-κB pathways.
Wang H, Wang Y, Chai Y, Zhang H, Chang Q, Li J, Zhang R, Bao J
Poultry science 2024 Oct;103(10):104100
Poultry science 2024 Oct;103(10):104100
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Lv F, Xie L, Li L, Lin J
Scientific reports 2024 Oct 8;14(1):23450
Scientific reports 2024 Oct 8;14(1):23450
Imperatorin attenuates CCl(4)-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways.
Zhao Z, Fan Q, Zhang C, Zheng L, Lin J, Chen M, Wu G, Li H, Huo H, Zhao Q, Luo M
European journal of pharmacology 2024 Oct 5;980:176833
European journal of pharmacology 2024 Oct 5;980:176833
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Guo T, Hu X, Du Z, Wang X, Lang J, Liu J, Xu H, Sun Z
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Co-Mn Complex Oxide Nanoparticles as Potential Reactive Oxygen Species Scavenging Agents for Pulmonary Fibrosis Treatment.
Yang W, Yuan H, Sun H, Hu T, Xu Y, Qiu Y, Li Y
Molecules (Basel, Switzerland) 2024 Oct 29;29(21)
Molecules (Basel, Switzerland) 2024 Oct 29;29(21)
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
Dai F, Zhang X, Ma G, Li W
International immunopharmacology 2024 Oct 25;140:112924
International immunopharmacology 2024 Oct 25;140:112924
The ASB@HNTs-PVA nanofiber membrane, possessing both anti-inflammatory and hemostatic activities, promotes the healing of T2D skin wounds.
Tang Y, Wang N, Liu W, Ding Q, Yang J, Wu X, Cheng Z, Hong B, Ding C
International immunopharmacology 2024 Oct 25;140:112780
International immunopharmacology 2024 Oct 25;140:112780
Soluble Epoxide Hydrolase Inhibition Attenuates Proteinuria by Alleviating Renal Inflammation and Podocyte Injuries in Adriamycin-Induced Nephropathy.
Niu Q, Guo Z, Liang Y, Zuo L
International journal of molecular sciences 2024 Oct 2;25(19)
International journal of molecular sciences 2024 Oct 2;25(19)
Integrated single-cell and spatial transcriptomics reveal microenvironment disruptions by androgen in mouse ovary.
Luo M, Yang X, Zhou M, Zhang J, Yu B, Lian H, Ye J
iScience 2024 Oct 18;27(10):111028
iScience 2024 Oct 18;27(10):111028
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Zhang Y, Li X, Dai Y, Han Y, Wei X, Wei G, Chen W, Kong S, He Y, Liu H, Ma N, Bin J, Tan N, He P, Liu Y
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Multifunctional chitosan-based hydrogels loaded with iridium nanoenzymes for skin wound repair.
Wang R, Xu S, Zhang M, Feng W, Wang C, Qiu X, Li J, Zhao W
Carbohydrate polymers 2024 Oct 15;342:122325
Carbohydrate polymers 2024 Oct 15;342:122325
Neuroprotective effect of emodin on Aβ(25-35)-induced cytotoxicity in PC12 cells involves Nrf2/GPX4 and TLR4/p-NF-κB/NLRP3 pathways.
Xia N, Xu L, Xu D, Huang M, Li Y, Mei Z, Yu Z
Brain research 2024 Oct 15;1841:149019
Brain research 2024 Oct 15;1841:149019
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Wang X, Wang K, Mao W, Fan Z, Liu T, Hong R, Chen H, Pan C
Environmental research 2024 Oct 1;258:119483
Environmental research 2024 Oct 1;258:119483
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
Ye J, Yin X, Xie S, Hua Q, Zhu J, Chen J, Zheng W, Cai L
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Xin C, Wei H, Mao R, Zhang G, Zhao T, Liu W
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
ZnO nanoparticles induce melanoma-like lesions via recruiting dermal dendritic cells in barrier-damaged skin in mice.
You M, Huang Y, Chen Y, Li D, Tang Y, Du YK, Yang H, Liang A, Hu G, Chen Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:114948
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:114948
Astrocytic purinergic signalling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Liu S, Cheng H, Cui L, Jin L, Li Y, Zhu C, Ji Q, Tang J
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes.
Ghosh R, Bishayi B
Cellular immunology 2024 Nov-Dec;405-406:104878
Cellular immunology 2024 Nov-Dec;405-406:104878
All-trans retinoic acid inhibits glioblastoma progression and attenuates radiation-induced brain injury.
Fu M, Zhang Y, Peng B, Luo N, Zhang Y, Zhu W, Yang F, Chen Z, Zhang Q, Li Q, Chen X, Liu Y, Long G, Hu G, Peng X
JCI insight 2024 Nov 8;9(21)
JCI insight 2024 Nov 8;9(21)
Ginsenoside Rk3 Treats Corneal Injury Through the HMGB1/TLR4/NF-κB Pathway.
Qu L, Huang Y, Wu Y, He L, Liu Y, Chen Z, Ma X, Fan D
Journal of agricultural and food chemistry 2024 Nov 6;72(44):24387-24399
Journal of agricultural and food chemistry 2024 Nov 6;72(44):24387-24399
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Ma SZ, Dong S, Zhou ZY, Ji XY, Zhang YY, Wang XQ, Zhang B
Journal of ethnopharmacology 2024 Nov 15;334:118565
Journal of ethnopharmacology 2024 Nov 15;334:118565
Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.
Zhang M, Zhang Y, Peng J, Huang Y, Gong Z, Lu H, Han L, Wang D
International immunopharmacology 2024 Nov 15;141:113012
International immunopharmacology 2024 Nov 15;141:113012
Chitosan/rutin multifunctional hydrogel with tunable adhesion, anti-inflammatory and antibacterial properties for skin wound healing.
An R, Shi C, Tang Y, Cui Z, Li Y, Chen Z, Xiao M, Xu L
Carbohydrate polymers 2024 Nov 1;343:122492
Carbohydrate polymers 2024 Nov 1;343:122492
TBPH-induced lung injury is induced by mitochondrial-derived ds-DNA-mediated inflammatory response.
Xing B, Lan H, Li H
Ecotoxicology and environmental safety 2024 Nov 1;286:117200
Ecotoxicology and environmental safety 2024 Nov 1;286:117200
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Cao J, Yu X, Liu J, Fu J, Wang B, Wu C, Zhang S, Chen H, Wang Z, Xu Y, Sui T, Chang J, Cao X
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Zhao Y, Wang Y, Zheng H, Xu Q, Zhou K, Liu H, Xia Y, Wei DH, Jiang M, Tang ZH, Liu LS, Zheng H, Jiang Z
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Poly (vinyl alcohol)/sodium alginate/carboxymethyl chitosan multifunctional hydrogel loading HKUST-1 nanoenzymes for diabetic wound healing.
Chai G, Wang N, Xu M, Ma L, Liu X, Ding Q, Zhang S, Li A, Xia G, Zhao Y, Liu W, Liang D, Ding C
International journal of biological macromolecules 2024 May;268(Pt 2):131670
International journal of biological macromolecules 2024 May;268(Pt 2):131670
Artificial nonenzymatic antioxidant Prussian blue/KGM-BSA nanocomposite hydrogel dressing as ROS scavenging for diabetic wound healing.
Tang DX, Liu K, Yang JY, Wang ZJ, Fu LL, Yang XJ, Li YS, Huang B, Liu Y
International journal of biological macromolecules 2024 May;266(Pt 1):131106
International journal of biological macromolecules 2024 May;266(Pt 1):131106
Polarization to M1-type microglia in the hippocampus is involved in depression-like behavior in a mouse model of olfactory dysfunction.
Takahashi K, Tsuji M, Nakagawasai O, Katsuyama S, Miyagawa K, Kurokawa K, Mochida-Saito A, Takeda H, Tadano T
Neurochemistry international 2024 May;175:105723
Neurochemistry international 2024 May;175:105723
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Zhou Z, Li Y, Wu S, Liu T, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Platinum-Loaded Cerium Oxide Capable of Repairing Neuronal Homeostasis for Cerebral Ischemia-Reperfusion Injury Therapy.
Zhang Q, Liu Z, Li B, Mu L, Sheng K, Xiong Y, Cheng J, Zhou J, Xiong Z, Zhou L, Jiang L, Wu J, Cai X, Zheng Y, Du W, Li Y, Zhu Y
Advanced healthcare materials 2024 May;13(13):e2303027
Advanced healthcare materials 2024 May;13(13):e2303027
Rap1GAP exacerbates myocardial infarction by regulating the AMPK/SIRT1/NF-κB signaling pathway.
Shan T, Li X, Xie W, Wang S, Gao Y, Zheng Y, Su G, Li Y, Zhao Z
Cellular signalling 2024 May;117:111080
Cellular signalling 2024 May;117:111080
Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury.
Wang J, Zhang H, Yuan H, Chen S, Yu Y, Zhang X, Gao Z, Du H, Li W, Wang Y, Xia P, Wang J, Song M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307233
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307233
3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure.
Zhang J, Chen X, Chai Y, Zhuo C, Xu Y, Xue T, Shao D, Tao Y, Li M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309899
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309899
Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice.
Li D, Yu SF, Lin L, Guo JR, Huang SM, Wu XL, You HL, Cheng XJ, Zhang QY, Zeng YQ, Pan XD
Journal of neuroinflammation 2024 May 9;21(1):123
Journal of neuroinflammation 2024 May 9;21(1):123
Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3.
Kundu A, Ghosh P, Bishayi B
International immunopharmacology 2024 May 30;133:112153
International immunopharmacology 2024 May 30;133:112153
Uterine Immunoprivileged Cells Restore Cardiac Function of Male Recipients After Myocardial Infarction.
Peng Z, Ludke A, Wu J, Li S, Alibhai FJ, Zhang Y, Fan Y, Song H, He S, Xie J, Li RK
Stem cells (Dayton, Ohio) 2024 May 15;42(5):430-444
Stem cells (Dayton, Ohio) 2024 May 15;42(5):430-444
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
Yan Y, Bai S, Han H, Dai J, Niu L, Wang H, Dong Q, Yin H, Yuan G, Pan Y
Cell communication and signaling : CCS 2024 May 15;22(1):272
Cell communication and signaling : CCS 2024 May 15;22(1):272
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Liu M, Huo X, Li C, Hu Y, Lei H, Wang D, Zhu L, Gu Y, Guo D, Huang L, Deng Y
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Xuebijing injection and its bioactive components alleviate nephrotic syndrome by inhibiting podocyte inflammatory injury.
Yuan S, Cao Y, Jiang J, Chen J, Huang X, Li X, Zhou J, Zhou Y, Zhou J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 May 1;196:106759
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 May 1;196:106759
Tetramethylpyrazine inhibits the inflammatory response by downregulating the TNFR1/IκB-α/NF-κB p65 pathway after spinal cord injury.
Liu G, Huo L, Deng B, Jiang S, Zhao Y, Mo Y, Bai H, Xu L, Hu C, Mu X
Toxicology and applied pharmacology 2024 Mar;484:116872
Toxicology and applied pharmacology 2024 Mar;484:116872
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Che J, Wang H, Dong J, Wu Y, Zhang H, Fu L, Zhang J
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
Glycation promotes pulp calcification in Type 2 diabetes rat model.
Takashima A, Miura J, Sugiyama K, Shimizu M, Okada M, Otani T, Nagashima T, Tsuda T, Araki T
Oral diseases 2024 Mar;30(2):593-603
Oral diseases 2024 Mar;30(2):593-603
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Zhang J, Zhang X, Liu X, Chen H, Wang J, Ji M
Cardiovascular toxicology 2024 Mar;24(3):302-320
Cardiovascular toxicology 2024 Mar;24(3):302-320
Schaftoside reduces inflammation in Aspergillus fumigatus keratitis through the inhibition of the TLR4/MyD88 pathway.
Lu D, Liu W, Yang H, Zong Y, Sun J, Sun X, Song S, Liu M, Kan J, Che C
Cytokine 2024 Mar;175:156483
Cytokine 2024 Mar;175:156483
Rescuing Nucleus Pulposus Cells from ROS Toxic Microenvironment via Mitochondria-Targeted Carbon Dot-Supported Prussian Blue to Alleviate Intervertebral Disc Degeneration.
Shi Y, Bu W, Chu D, Lin W, Li K, Huang X, Wang X, Wu Y, Wu S, Li D, Xu Z, Cao Z, Chen H, Wang H
Advanced healthcare materials 2024 Mar;13(8):e2303206
Advanced healthcare materials 2024 Mar;13(8):e2303206
Characterization of Chitosan-Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application.
Feng M, Zeng X, Lin Q, Wang Y, Wei H, Yang S, Wang G, Chen X, Guo M, Yang X, Hu J, Zhang Y, Yang X, Du Y, Zhao Y
Advanced healthcare materials 2024 Mar;13(7):e2302877
Advanced healthcare materials 2024 Mar;13(7):e2302877
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Liu J, Gao Y, Zhang H, Hao Z, Zhou G, Wen H, Su Q, Tong C, Yang X, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.
Chang BT, Wang Y, Tu WL, Zhang ZQ, Pu YF, Xie L, Yuan F, Gao Y, Xu N, Yao Q
Food science & nutrition 2024 Mar;12(3):2068-2080
Food science & nutrition 2024 Mar;12(3):2068-2080
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs).
Wang W, Zhang ZQ, Zhang YC, Wu YQ, Yang Z, Zheng YZ, Lu JH, Tu PF, Zeng KW
Chinese medicine 2024 Mar 5;19(1):42
Chinese medicine 2024 Mar 5;19(1):42
Xianling Lianxia formula enhances the inhibitory effects of trastuzumab on HER2-positive breast cancer.
Li F, Wu Y, Shi Y, Liu X, Xie Y, Liu S
Acta biochimica et biophysica Sinica 2024 Mar 25;56(3):462-473
Acta biochimica et biophysica Sinica 2024 Mar 25;56(3):462-473
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Li XY, Yin X, Lu JJ, Li QR, Xing WQ, Han Q, Ji H, Li SZ, Yang HM, Guo JR, Wang ZQ, Xu B
Cells 2024 Mar 25;13(7)
Cells 2024 Mar 25;13(7)
Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation.
Wang YY, Zhu GQ, Xia K, Zeng HB, He YH, Xie H, Wang ZX, Xu R
Molecular medicine (Cambridge, Mass.) 2024 Mar 22;30(1):41
Molecular medicine (Cambridge, Mass.) 2024 Mar 22;30(1):41
Effects of chronic low-level lead (Pb) exposure on cognitive function and hippocampal neuronal ferroptosis: An integrative approach using bioinformatics analysis, machine learning, and experimental validation.
Cao Y, Zhao W, Zhong Y, Jiang X, Mei H, Chang Y, Wu D, Dou J, Vasquez E, Shi X, Yang J, Jia Z, Tan X, Li Q, Dong Y, Xie R, Gao J, Wu Y, Liu Y
The Science of the total environment 2024 Mar 20;917:170317
The Science of the total environment 2024 Mar 20;917:170317
Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice.
Luo S, Meng X, Ai J, Zhang Z, Dai Y, Yu X
International journal of molecular sciences 2024 Mar 18;25(6)
International journal of molecular sciences 2024 Mar 18;25(6)
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Chen B, Li YF, Fang Z, Cai WY, Tian ZQ, Li D, Wang ZM
Heliyon 2024 Mar 15;10(5):e27163
Heliyon 2024 Mar 15;10(5):e27163
Two-electron oxidized polyphenol chemistry-inspired superhydrophilic drug-carrying coatings for the construction of multifunctional nasolacrimal duct stents.
Xiao W, Wang B, Wang X, Zhang G, Zhao Y, Zhang Z, Li L, Qu C
Journal of materials chemistry. B 2024 Mar 13;12(11):2877-2893
Journal of materials chemistry. B 2024 Mar 13;12(11):2877-2893
Atractylenolide-III attenuates osteoarthritis by repolarizing macrophages through inactivating TLR4/NF-κB signaling.
Yi G, Zhang R, Li M, Song X, Li S
International immunopharmacology 2024 Mar 10;129:111629
International immunopharmacology 2024 Mar 10;129:111629
Quercetin and Kaempferol inhibit HMC-1 activation via SOCE/NFATc2 signaling and suppress hippocampal mast cell activation in lipopolysaccharide-induced depressive mice.
Su P, Li Z, Yan X, Wang B, Bai M, Li Y, Xu E
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):945-960
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):945-960
MANF Alleviates Sevoflurane-Induced Cognitive Impairment in Neonatal Mice by Modulating Microglial Activation and Polarization.
Gao J, Zhang H, Zhou L, Liu J, Zhuo E, Shen Y, Liu X, Shen Q
Molecular neurobiology 2024 Jun;61(6):3357-3368
Molecular neurobiology 2024 Jun;61(6):3357-3368
Dihydroquercetin alleviates dopamine neuron loss via regulating TREM2 activation.
Yang R, Li DD, Li XX, Yang XX, Gao HM, Zhang F
International journal of biological macromolecules 2024 Jun;269(Pt 2):132179
International journal of biological macromolecules 2024 Jun;269(Pt 2):132179
Collagen sponge scaffolds loaded with Trichostatin A pretreated BMSCs-derived exosomes regulate macrophage polarization to promote skin wound healing.
Wang T, Xue Y, Zhang W, Zheng Z, Peng X, Zhou Y
International journal of biological macromolecules 2024 Jun;269(Pt 2):131948
International journal of biological macromolecules 2024 Jun;269(Pt 2):131948
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Li B, Jiang XF, Dong YJ, Zhang YP, He XL, Zhou CL, Ding YY, Wang N, Wang YB, Cheng WQ, Jiang NH, Su J, Lv GY, Chen SH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Investigation of the underlying mechanism of Buyang Huanwu decoction in ischemic stroke by integrating systems pharmacology-proteomics and in vivo experiments.
Liao W, Wang P, He Y, Liu Z, Wang L
Fitoterapia 2024 Jun;175:105935
Fitoterapia 2024 Jun;175:105935
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Xie Y, Li J, Tao Q, Wu Y, Liu Z, Chen Y, Zeng C
Scientific reports 2024 Jun 7;14(1):13102
Scientific reports 2024 Jun 7;14(1):13102
Hypoxia-inducible factor prolyl hydroxylase inhibitor alleviates heatstroke-induced acute kidney injury by activating BNIP3-mediated mitophagy.
Wang L, Song Y, Zhang P, Chen W, Xiao F, Zhou P, Yang X, Dai H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23723
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23723
Cordycepin Enhances the Therapeutic Efficacy of Doxorubicin in Treating Triple-Negative Breast Cancer.
Huang H, Li X, Wu W, Liu C, Shao Y, Wu X, Fu J
International journal of molecular sciences 2024 Jun 27;25(13)
International journal of molecular sciences 2024 Jun 27;25(13)
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Wang G, Ma X, Huang W, Wang S, Lou A, Wang J, Tu Y, Cui W, Zhou W, Zhang W, Li Y, Geng S, Meng Y, Li X
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway.
Han B, Zhang Y, Liu C, Ji P, Xing Z, Geng X, Chi K, Gong M, Li Y, Zhang Y, Fu Z, Hong Q, Cai G, Chen X, Sun X
iScience 2024 Jun 21;27(6):110045
iScience 2024 Jun 21;27(6):110045
The Role of Grifola frondosa Polysaccharide in Preventing Skeletal Muscle Atrophy in Type 2 Diabetes Mellitus.
She Y, Ma Y, Zou P, Peng Y, An Y, Chen H, Luo P, Wei S
Life (Basel, Switzerland) 2024 Jun 21;14(7)
Life (Basel, Switzerland) 2024 Jun 21;14(7)
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
Zou S, Wu Y, Wen M, Liu J, Chen M, Yuan J, Zhou B
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway.
Du MW, Zhu XL, Zhang DX, Chen XZ, Yang LH, Xiao JZ, Fang WJ, Xue XC, Pan WH, Liao WQ, Yang T
World journal of diabetes 2024 Jun 15;15(6):1299-1316
World journal of diabetes 2024 Jun 15;15(6):1299-1316
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice.
Zhao W, Zhao S, Wei R, Wang Z, Zhang F, Zong F, Zhang HT
International immunopharmacology 2024 Jun 15;134:112185
International immunopharmacology 2024 Jun 15;134:112185
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Gao Y, Hao Z, Zhang H, Liu J, Zhou G, Wen H, Su Q, Tong C, Huang S, Wang X
Chemico-biological interactions 2024 Jun 1;396:111044
Chemico-biological interactions 2024 Jun 1;396:111044
Structural elucidation and anti-psoriasis activity of a novel polysaccharide from Saussurea Costus.
Gong X, Zhang Z, Shi X, Zhu Y, Ali F, Dong Y, Zhang F, Zhang B
Carbohydrate polymers 2024 Jun 1;333:121963
Carbohydrate polymers 2024 Jun 1;333:121963
Type 2 diabetes aggravates periodontitis-induced pathological changes in the dental pulp.
Yang T, Zhou B, Shan Z, Hu L
Oral diseases 2024 Jul;30(5):3250-3260
Oral diseases 2024 Jul;30(5):3250-3260
Chitosan-modified dihydromyricetin liposomes promote the repair of liver injury in mice suffering from diabetes mellitus.
Ding Q, Liu X, Zhang S, Chai G, Ma S, Sun S, Shen L, Gao Y, Ding C, Zhao T, Liu W
International journal of biological macromolecules 2024 Jul;273(Pt 2):133040
International journal of biological macromolecules 2024 Jul;273(Pt 2):133040
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
Xie L, Zhang G, Wu Y, Hua Y, Ding W, Han X, Liu B, Zhou C, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
Engineering Efferocytosis-Mimicking Nanovesicles to Regulate Joint Anti-Inflammation and Peripheral Immunosuppression for Rheumatoid Arthritis Therapy.
Yuan S, Chai Y, Xu J, Wang Y, Jiang L, Lu N, Jiang H, Wang J, Pan X, Deng J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2404198
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2404198
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Yang Y, Zhao C, Yang Z, Du C, Chang Z, Wen X, Zhang X, Liu Y, Hu L, Gao Z
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Liu Y, Luo H, Liu B, Zhou T, Zhang Z, Liu Z
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
Fu Q, Zhang JJ, Zhu QF, Yu LL, Wang F, Li J, He X, Ao JL, Xu GB, Wei MC, Liao XJ, Liao SG
Biochemical and biophysical research communications 2024 Jul 5;716:150038
Biochemical and biophysical research communications 2024 Jul 5;716:150038
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
Huang R, Liu L, Shen K, Duan C, Fan Z
Journal of integrative neuroscience 2024 Jul 5;23(7):124
Journal of integrative neuroscience 2024 Jul 5;23(7):124
Evaluation of transurethral GreenLight laser-selective vaporization for refractory overactive bladder in women.
Du K, Sun X, Yang F, Qiu Z, Li L, Zhao Y, Zhang H
Translational andrology and urology 2024 Jul 31;13(7):1164-1172
Translational andrology and urology 2024 Jul 31;13(7):1164-1172
A classic prescription alleviates inflammation in CUMS model mice via modulating MYDGF/MAP4K4/NF-κB signaling pathway, verified through UPLC-HRMS and proteomics analysis.
Huang R, Gong S, Xiong B, Yang X, Chen C, Song W, Wu R, Yang L, Yin J, Chen M
Heliyon 2024 Jul 30;10(14):e34596
Heliyon 2024 Jul 30;10(14):e34596
Pathological polarizations from microglia to astrocyte contributes to spatial memory deficit in methamphetamine abstinence mice.
Mai Y, Cheng Z, Wang Z, Hu T, Zhang Y, Yuan X, Xu X, Fan Y, Ge F, Shi P, Wang J, Yang X, Guan X
Cerebral cortex (New York, N.Y. : 1991) 2024 Jul 3;34(7)
Cerebral cortex (New York, N.Y. : 1991) 2024 Jul 3;34(7)
Pain Relief, Functional Recovery, and Chondroprotective Effects of Angelica gigas Nakai in Osteoarthritis Due to Its Anti-Inflammatory Property: An In Vitro and In Vivo Study.
Jo HG, Baek CY, Hwang Y, Baek E, Song HS, Lee D
Nutrients 2024 Jul 26;16(15)
Nutrients 2024 Jul 26;16(15)
The regulatory mechanism of cyclic GMP-AMP synthase on inflammatory senescence of nucleus pulposus cell.
Sun R, Wang F, Zhong C, Shi H, Peng X, Gao JW, Wu XT
Journal of orthopaedic surgery and research 2024 Jul 22;19(1):421
Journal of orthopaedic surgery and research 2024 Jul 22;19(1):421
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
Wu Z, Yang L, Wang R, Yang J, Liang P, Ren W, Yu H
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
The Contrasting Effects of Two Distinct Exercise Training Modalities on Exhaustive Exercise-Induced Muscle Damage in Mice May Be Associated with Alterations in the Gut Microbiota.
Zhang Y, Wang C, Lang H, Yu H, Zhou M, Rao X, Zhang Q, Yi L, Zhu J, Mi M
International journal of molecular sciences 2024 Jul 17;25(14)
International journal of molecular sciences 2024 Jul 17;25(14)
TAT-beclin1 treatment accelerates the development of atherosclerotic lesions in ApoE-deficient mice.
Liu L, Wang Q, Li Y, Cai J, Wang Y, Li Y, Wang R, Sun L, Zheng X, Yin A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23765
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23765
Effect of luteolin on oxidative stress and inflammation in the human osteoblast cell line hFOB1.19 in an inflammatory microenvironment.
Peng Z, Zhang W, Hong H, Liu L
BMC pharmacology & toxicology 2024 Jul 12;25(1):40
BMC pharmacology & toxicology 2024 Jul 12;25(1):40
Rescue of nucleus pulposus cells from an oxidative stress microenvironment via glutathione-derived carbon dots to alleviate intervertebral disc degeneration.
Bu W, Shi Y, Huang X, Wu S, Jiang L, Pan C, Li D, Xu Z, Wang H, Chen H, Du J
Journal of nanobiotechnology 2024 Jul 12;22(1):412
Journal of nanobiotechnology 2024 Jul 12;22(1):412
Ursolic acid molecules dock MAPK1 to modulate gut microbiota diversity to reduce neuropathic pain.
Rong ZJ, Chen M, Cai HH, Liu GH, Chen JB, Wang H, Zhang ZW, Huang YL, Ni SF
Neuropharmacology 2024 Jul 1;252:109939
Neuropharmacology 2024 Jul 1;252:109939
Porphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis.
Oriuchi M, Lee S, Uno K, Sudo K, Kusano K, Asano N, Hamada S, Hatta W, Koike T, Imatani A, Masamune A
Digestive diseases and sciences 2024 Jan;69(1):95-111
Digestive diseases and sciences 2024 Jan;69(1):95-111
Uric acid promotes interleukin-17 expression to cause kidney injury.
Yang L, He T, Yu Y
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
The P38MAPK/ATF2 signaling pathway is involved in PND in mice.
Zhu M, Long S, Tao Y, Zhang Z, Zhou Z, Wang X, Chen W
Experimental brain research 2024 Jan;242(1):109-121
Experimental brain research 2024 Jan;242(1):109-121
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
Wu H, Wang T, Liang Y, Chen L, Li Z
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
Acacetin inhibits activation of microglia to improve neuroinflammation after subarachnoid hemorrhage through the PERK signaling pathway mediated autophagy.
Liu Y, Tang J, Hou Y, Li L, Li W, Yu L, Wang X, Sui C
Human & experimental toxicology 2024 Jan-Dec;43:9603271241251447
Human & experimental toxicology 2024 Jan-Dec;43:9603271241251447
S-amlodipine induces liver inflammation and dysfunction through the alteration of intestinal microbiome in a rat model.
Liu X, Fang H, Pan L, Zhang P, Lin H, Gao H, Ye C, Mao D, Luo Y
Gut microbes 2024 Jan-Dec;16(1):2316923
Gut microbes 2024 Jan-Dec;16(1):2316923
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Core-Shell Structured Nanozyme with PDA-Mediated Enhanced Antioxidant Efficiency to Treat Early Intervertebral Disc Degeneration.
Wang J, Wu R, Liu Z, Qi L, Xu H, Yang H, Li Y, Liu L, Feng G, Zhang L
ACS applied materials & interfaces 2024 Jan 31;16(4):5103-5119
ACS applied materials & interfaces 2024 Jan 31;16(4):5103-5119
Yi-shen-hua-shi granules modulate immune and inflammatory damage via the ALG3/PPARγ/NF-κB pathway in the treatment of immunoglobulin a nephropathy.
Xu R, Zhang J, Hu X, Xu P, Huang S, Cui S, Guo Y, Yang H, Chen X, Jiang C
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117204
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117204
The protective effect of apolipoprotein H in paediatric sepsis.
Yu Z, Xiao C, Liu R, Pi D, Jin B, Zou Z, Xu F
Critical care (London, England) 2024 Jan 30;28(1):36
Critical care (London, England) 2024 Jan 30;28(1):36
The lncRNA GAS5 upregulates ANXA2 to mediate the macrophage inflammatory response during atherosclerosis development.
Xue Y, Hu Y, Yu S, Zhu W, Liu L, Luo M, Luo S, Shen J, Huang L, Liu J, Lv D, Zhang W, Wang J, Li X
Heliyon 2024 Jan 30;10(2):e24103
Heliyon 2024 Jan 30;10(2):e24103
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Khan S, Wang T, Cobo ER, Liang B, Khan MA, Xu M, Qu W, Gao J, Barkema HW, Kastelic JP, Liu G, Han B
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Network pharmacology and in vivo evidence of the pharmacological mechanism of geniposide in the treatment of atherosclerosis.
Ma G, Dong Q, Li F, Jin Z, Pi J, Wu W, Li J
BMC complementary medicine and therapies 2024 Jan 24;24(1):53
BMC complementary medicine and therapies 2024 Jan 24;24(1):53
Tafluprost promotes axon regeneration after optic nerve crush via Zn(2+)-mTOR pathway.
Wu S, Liu C, Tang J, Wu C, Zhang Q, Liu Z, Han J, Xue J, Lin J, Chen Y, Yang J, Zhuo Y, Li Y
Neuropharmacology 2024 Jan 1;242:109746
Neuropharmacology 2024 Jan 1;242:109746
Marine bromophenols suppressed choroidal neovascularization by targeting HUWE1 through NF-κb signaling pathway.
Ou K, Li Y, Wang Y, Liu J, Luo Y, Jiang J, Dan J, Tang D, Chen Z, Wu J
International journal of biological macromolecules 2024 Feb;257(Pt 1):128620
International journal of biological macromolecules 2024 Feb;257(Pt 1):128620
Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages.
Ghosh R, Bishayi B
Microbial pathogenesis 2024 Feb;187:106518
Microbial pathogenesis 2024 Feb;187:106518
Liver toxicity in rats after subchronic exposure to HTP aerosol and cigarette smoke.
Tian Y, Wang H, Han S, Fu Y, Lu F, Wang W, Li X, Ma S, Feng P, Shi Z, Chen H, Hou H
Toxicology research 2024 Feb;13(1):tfae002
Toxicology research 2024 Feb;13(1):tfae002
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
He Y, Liu F, He M, Long F, Hu D, Chen J, Fang M, Wang Z
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway.
Li W, Cao J, Liu J, Chen S, Dai M, Zhang M, Hou X, Wang J, Kang Z
Heliyon 2024 Feb 29;10(4):e24749
Heliyon 2024 Feb 29;10(4):e24749
An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering.
Inoue M, Tsuji Y, Kashiwada A, Yokoyama A, Iwata A, Abe Y, Kamada H, Tsunoda SI
Biochemical and biophysical research communications 2024 Feb 19;697:149498
Biochemical and biophysical research communications 2024 Feb 19;697:149498
Nanohybrid dual-network chitosan-based hydrogels: Synthesis, characterization, quicken infected wound healing by angiogenesis and immune-microenvironment regulation.
Liu Y, Zhao F, Song T, Tang M, Tian L, He T, Li D, Xiao Y, Zhang X
Carbohydrate polymers 2024 Feb 1;325:121589
Carbohydrate polymers 2024 Feb 1;325:121589
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Liu MY, Xu KH, Liu S, Xiao WJ
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Hong R, Shi Y, Fan Z, Gao Y, Chen H, Pan C
Toxicology 2024 Dec;509:153996
Toxicology 2024 Dec;509:153996
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
STING Activation in Macrophages and Microglia Drives Poststroke Inflammation: Implications for Neuroinflammatory Mechanisms and Therapeutic Interventions.
Liu Z, Qin Q, Wang S, Kang X, Liu Y, Wei L, Lu Z, Cai W, Hu M
CNS neuroscience & therapeutics 2024 Dec;30(12):e70106
CNS neuroscience & therapeutics 2024 Dec;30(12):e70106
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
Guo K, Li G, Yu Q, Yang Y, Liu H, Zhao Y, Huang Y, Zhang H, Li W
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
Zhang Y, Wang X, Huang J, Zhang X, Bu L, Zhang Y, Liang F, Wu S, Zhang M, Zhang L, Zhang L
Aging cell 2024 Dec;23(12):e14333
Aging cell 2024 Dec;23(12):e14333
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Zhao Y, Zheng G, Yang S, Liu S, Wu Y, Miao Y, Liang Z, Hua Y, Zhang J, Shi J, Li D, Cheng Y, Zhang Y, Chen Y, Fan G, Ma C
British journal of pharmacology 2024 Dec;181(23):4822-4844
British journal of pharmacology 2024 Dec;181(23):4822-4844
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Spatio-temporal expression of Sox2(+) progenitor cells regulates the regeneration of rat submandibular gland.
Li D, Qu Y, Wang B, Zhang H, Qin L
Archives of oral biology 2024 Dec;168:106080
Archives of oral biology 2024 Dec;168:106080
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway.
Gao Y, Wang S, Gao Y, Yang L
Basic & clinical pharmacology & toxicology 2024 Dec;135(6):705-719
Basic & clinical pharmacology & toxicology 2024 Dec;135(6):705-719
Jia Wei Qingxin Lotus Seed Drink ameliorates epithelial mesenchymal transition injury in diabetic kidney disease via inhibition of JMJD1C/SP1/ZEB1 signaling pathway.
Xie J, Lin H, Jin F, Luo Y, Yang P, Song J, Yao W, Lin W, Yuan D, Zuo A, Sun J, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156142
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156142
Sphingosine-1-phosphate receptor 3 promotes neuronal apoptosis via the TNF-α/caspase-3 signaling pathway after acute intracerebral hemorrhage.
Song D, Li M, Zhang L, Zhang K, An Y, Feng M, Wang F, Yeh CT, Wang J, Guo F
Molecular and cellular neurosciences 2024 Dec;131:103979
Molecular and cellular neurosciences 2024 Dec;131:103979
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Chen X, Wang L, Zhang J, Yan H, Wang S, Xiao J
Advanced healthcare materials 2024 Dec;13(32):e2401507
Advanced healthcare materials 2024 Dec;13(32):e2401507
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
Ma Z, Chen X, Xiong M, Wang H, Sun C, Tang W, Li J, Li X, Ma H, Ye X
Journal of ethnopharmacology 2024 Dec 5;335:118644
Journal of ethnopharmacology 2024 Dec 5;335:118644
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
Jiang HY, Gu WW, Gan J, Yang Q, Shi Y, Lian WB, Xu HR, Yang SH, Yang L, Zhang X, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):113053
International immunopharmacology 2024 Dec 5;142(Pt A):113053
Involvement of necroptosıs and apoptosıs ın protectıve effects of cyclosporın a on ischemıa-reperfusıon injury in rat kıdney.
Ozgen ZE, Erdinc M, Kaya MS, Aktar F, Ozekinci SO, Erdinc L, Uyar E
Journal of molecular histology 2024 Dec 4;56(1):30
Journal of molecular histology 2024 Dec 4;56(1):30
Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp.
Xu X, Wang Y, Wu X, Cai T, Dong L, Liang S, Zhu L, Song X, Dong Y, Zheng Y, Li L, Sun W
Biochemical and biophysical research communications 2024 Dec 31;741:151033
Biochemical and biophysical research communications 2024 Dec 31;741:151033
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
Wang Z, Jia S, Kang X, Chen S, Zhang L, Tian Z, Liang X, Meng C
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
Carbon monoxide as a negative feedback mechanism on HIF-1α in the progression of metabolic-associated fatty liver disease.
Cui Y, Yang K, Guo C, Xia Z, Jiang B, Xue Y, Song B, Hu W, Zhang M, Wei Y, Zhang C, Zhang S, Fang J
Nitric oxide : biology and chemistry 2024 Dec 1;153:1-12
Nitric oxide : biology and chemistry 2024 Dec 1;153:1-12
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling.
Pu Z, Ge F, Zhou Y, Liu A, Yang C
Cytotechnology 2024 Aug;76(4):441-452
Cytotechnology 2024 Aug;76(4):441-452
Membrane Fusion-Mediated Loading of Therapeutic siRNA into Exosome for Tissue-Specific Application.
Xie M, Wu Y, Zhang Y, Lu R, Zhai Z, Huang Y, Wang F, Xin C, Rong G, Zhao C, Jiang K, Zhou X, Zhou X, Zhu X, Hong J, Zhang C
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2403935
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2403935
Photocrosslinked carboxymethylcellulose-based hydrogels: Synthesis, characterization for curcumin delivery and wound healing.
Wang J, Ma Y, Meng Q, Yang Y, Zhang R, Zhong S, Gao Y, He W, Cui X
International journal of biological macromolecules 2024 Aug;275(Pt 1):133558
International journal of biological macromolecules 2024 Aug;275(Pt 1):133558
PL-Relief(TM)plus Alleviates Atopic Dermatitis and Regulates Inflammatory Responses via Inhibiting NF-κB Signaling Pathway.
Zhang X, Shen Z, Zhu W, Lin L, Fan Y, Cheng X, Yu M, Yu S, Zhao B
Chemistry & biodiversity 2024 Aug;21(8):e202400349
Chemistry & biodiversity 2024 Aug;21(8):e202400349
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
Zhu J, Liu Q, Chen Y, Zhang J, Xu Q, Wu Z
Heliyon 2024 Aug 30;10(16):e36079
Heliyon 2024 Aug 30;10(16):e36079
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
Xie X, Wang K, Shen X, Li X, Wang S, Yuan S, Li B, Wang Z
Journal of hazardous materials 2024 Aug 15;475:134854
Journal of hazardous materials 2024 Aug 15;475:134854
CCR5 antagonist maraviroc alleviates doxorubicin-induced neuroinflammation and neurobehavioral deficiency by regulating NF-κB/NLRP3 signaling in a breast cancer mouse model.
Wu Y, Che J, Dong J, Zhang X, Deng Y, Chen W, Zhang J
Neuropharmacology 2024 Aug 15;254:109981
Neuropharmacology 2024 Aug 15;254:109981
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
Fei F, Chen Z, Tao Y, Jiang X, Xu X, Ma Y, Feng P, Wang P
Heliyon 2024 Aug 15;10(15):e35363
Heliyon 2024 Aug 15;10(15):e35363
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Shang S, Zhuang K, Chen J, Zhang M, Jiang S, Li W
Bioactive materials 2024 Apr;34:298-310
Bioactive materials 2024 Apr;34:298-310
Danshensu methyl ester attenuated LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway.
Han X, Ding W, Qu G, Li Y, Wang P, Yu J, Liu M, Chen X, Xie S, Feng J, Xu S
Respiratory physiology & neurobiology 2024 Apr;322:104219
Respiratory physiology & neurobiology 2024 Apr;322:104219
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091
Aging cell 2024 Apr;23(4):e14091
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Ding M, Zhu Y, Xu X, He H, Jiang T, Mo X, Wang Z, Yu W, Ou H
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Investigating the Mechanistic of Danhong Injection in Brain Damage Caused by Cardiac I/R Injury via Bioinformatics, Computer Simulation, and Experimental Validation.
Wang J, Guo Y, Zhou H, Hua Y, Wan H, Yang J
ACS omega 2024 Apr 23;9(16):18341-18357
ACS omega 2024 Apr 23;9(16):18341-18357
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
Yang L, Zhou P, Li R, Yin Y, Xie G, Shi L, Zhang P, Tao K
Molecular biology reports 2024 Apr 20;51(1):533
Molecular biology reports 2024 Apr 20;51(1):533
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathway.
You X, Qiu J, Li Q, Zhang Q, Sheng W, Cao Y, Fu W
BMC cancer 2024 Apr 15;24(1):472
BMC cancer 2024 Apr 15;24(1):472
5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion.
Liao C, Guo J, Rui J, Gao K, Lao J, Zhou Y
Physiology & behavior 2024 Apr 1;277:114503
Physiology & behavior 2024 Apr 1;277:114503
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
Hu Y, Hu C, Yin J, Zhong J, Deng Y, Yang G
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
VCAM1 Drives Vascular Inflammation Leading to Continuous Cortical Neuronal Loss Following Chronic Cerebral Hypoperfusion.
Sun R, Shang J, Yan X, Zhao J, Wang W, Wang W, Li W, Gao C, Wang F, Zhang H, Wang Y, Cao H, Zhang J
Journal of Alzheimer's disease : JAD 2023;91(4):1541-1555
Journal of Alzheimer's disease : JAD 2023;91(4):1541-1555
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
Li Q, Li Z, Liu C, Xu M, Li T, Wang Y, Feng J, Yin X, Du X, Lu C
The American journal of Chinese medicine 2023;51(4):929-951
The American journal of Chinese medicine 2023;51(4):929-951
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Chen Y, Liu Y, Li H, Huna R, Tan X, Li N, Zhang Y, Jiao X, Liu M
Journal of applied oral science : revista FOB 2023;31:e20220404
Journal of applied oral science : revista FOB 2023;31:e20220404
Inhibition of Galectin-3 in a Rat Model of Epilepsy and Kainate-Activated BV2 Cells Limits Microglial Activation Through the NLRP3/Pyroptosis Pathway.
Sun W, Hao Y, Li C, Zhao Y, Yu H, Wang L
Neuroimmunomodulation 2023;30(1):325-337
Neuroimmunomodulation 2023;30(1):325-337
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Li LZ, Wang XM, Feng XJ, Liu K, Li B, Zhu LJ, Xu WF, Zheng X, Dong YJ, He XL, Guan HR, Ding YY, Wu HS, Zhou CJ, Ye SY, Zhang BB, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.
Wei W, Lin Z, Xu P, Lv X, Lin L, Li Y, Zhou Y, Lu T, Xue X
Neural plasticity 2023;2023:9206875
Neural plasticity 2023;2023:9206875
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Liu PL, Diao JY, Wang Q, Liu H, Zhang Y, Liang JQ, Zhang F, Liang XJ, Zhao HM
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis.
Sun R, Zhu J, Sun K, Gao L, Zheng B, Shi J
International journal of medical sciences 2023;20(13):1679-1697
International journal of medical sciences 2023;20(13):1679-1697
Palmitate lipotoxicity is closely associated with the fatty acid-albumin complexes in BV-2 microglia.
Yang Y, Yu Q, Li B, Yang Z, Zhang S, Yuan F
PloS one 2023;18(4):e0281189
PloS one 2023;18(4):e0281189
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Zhang H, Zang C, Zhao W, Zhang L, Liu R, Feng Z, Wu J, Cui R
International journal of nanomedicine 2023;18:7047-7063
International journal of nanomedicine 2023;18:7047-7063
Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.
Yan Y, Yu L, Chen B, Cao C, Zhao H, Wang Q, Xie D, Xi Y, Zhang C, Cheng J
Journal of inflammation research 2023;16:6179-6193
Journal of inflammation research 2023;16:6179-6193
Dapagliflozin promotes angiogenesis in hindlimb ischemia mice by inducing M2 macrophage polarization.
Yang H, Lan W, Liu W, Chen T, Tang Y
Frontiers in pharmacology 2023;14:1255904
Frontiers in pharmacology 2023;14:1255904
IL-37 counteracts inflammatory injury in the temporomandibular joint via the intracellular pathway.
Li J, Peng S, Yan Y, Yan S, Cao X, Li Y, Zhu L, Xu J
Frontiers in pharmacology 2023;14:1250216
Frontiers in pharmacology 2023;14:1250216
The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy.
Ma Y, Chen Y, Xu H, Du N
Frontiers in immunology 2023;14:1228399
Frontiers in immunology 2023;14:1228399
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Guo J, Zhou M, Zhao M, Li S, Fang Z, Li A, Zhang M
Frontiers in immunology 2023;14:1114620
Frontiers in immunology 2023;14:1114620
Exploring the molecular mechanism of notoginsenoside R1 in sepsis-induced cardiomyopathy based on network pharmacology and experiments validation.
Shao R, Li W, Chen R, Li K, Cao Y, Chen G, Jiang L
Frontiers in pharmacology 2023;14:1101240
Frontiers in pharmacology 2023;14:1101240
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Locally controlled release of immunosuppressive promotes survival of transplanted adult spinal cord tissue.
Wang Z, Li Y, Sun C, Cui P, Han Y, Wu T, Xu B, Zhang C, Shi L, Dai J
Regenerative biomaterials 2023;10:rbac097
Regenerative biomaterials 2023;10:rbac097
Normothermic ex vivo heart perfusion with NLRP3 inflammasome inhibitor Mcc950 treatment improves cardiac function of circulatory death hearts after transplantation.
Xu L, Zeng Z, Niu C, Liu D, Lin S, Liu X, Szabó G, Lu J, Zheng S, Zhou P
Frontiers in cardiovascular medicine 2023;10:1126391
Frontiers in cardiovascular medicine 2023;10:1126391
N-Acetylcysteine-Derived Carbon Dots for Free Radical Scavenging in Intervertebral Disc Degeneration.
Wu S, Shi Y, Jiang L, Bu W, Zhang K, Lin W, Pan C, Xu Z, Du J, Chen H, Wang H
Advanced healthcare materials 2023 Sep;12(24):e2300533
Advanced healthcare materials 2023 Sep;12(24):e2300533
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Zhang L, Yang J, Liu W, Ding Q, Sun S, Zhang S, Wang N, Wang Y, Xi S, Liu C, Ding C, Li C
International journal of biological macromolecules 2023 Sep 30;249:126014
International journal of biological macromolecules 2023 Sep 30;249:126014
Glymphatic Dysfunction in Migraine Mice Model.
Huang W, Zhang Y, Zhou Y, Zong J, Qiu T, Hu L, Pan S, Xiao Z
Neuroscience 2023 Sep 15;528:64-74
Neuroscience 2023 Sep 15;528:64-74
Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO-Induced Renal Fibrosis.
Zhang B, Chen ZY, Jiang Z, Huang S, Liu XH, Wang L
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13284-13303
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13284-13303
Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation.
Pan T, Xiao Q, Fan HJ, Xu L, Qin SC, Yang LX, Jin XM, Xiao BG, Zhang B, Ma CG, Chai Z
Metabolic brain disease 2023 Oct;38(7):2211-2222
Metabolic brain disease 2023 Oct;38(7):2211-2222
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Fitoterapia 2023 Oct;170:105652
Fitoterapia 2023 Oct;170:105652
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Epithelial-specific deletion of FAM20A leads to short root defects.
Liu L, Yao L, Lu Z, Jiang L, Zhang X, Liu X, Zhang W, Luan X, Zhang S, Xu W, Wang T, Zhang F, Wei X, Da J, Wang J, Zhang J, Li Y, Jin H, Zhang B
Gene 2023 Oct 30;884:147731
Gene 2023 Oct 30;884:147731
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
Liu W, Liu H, Wang Y, Zhao Z, Balasubramanian B, Jha R
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Agaricus blazei Murrill Polysaccharide Attenuates Periodontitis via H(2) S/NRF2 Axis-Boosted Appropriate Level of Autophagy in PDLCs.
Yuan W, Huang M, Wu Y, Liu J, Zhou X, Wang J, Liu J
Molecular nutrition & food research 2023 Nov;67(22):e2300112
Molecular nutrition & food research 2023 Nov;67(22):e2300112
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Li S, Xie J, Li K, Bai Y, Jiang Z, Xiong X
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838
Biochemical pharmacology 2023 Nov;217:115838
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Ma MH, Gao LL, Chen CB, Gu FL, Wu SQ, Li F, Han BX
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Role of corn silk for the treatment of Alzheimer's disease: A mechanism research based on network pharmacology combined with molecular docking and experimental validation.
Tao TZ, Wang L, Liu J
Chemical biology & drug design 2023 Nov;102(5):1231-1247
Chemical biology & drug design 2023 Nov;102(5):1231-1247
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Scientific reports 2023 Nov 14;13(1):19864
Scientific reports 2023 Nov 14;13(1):19864
Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.
Wang Z, Himanen SV, Haikala HM, Friedel CC, Vihervaara A, Barborič M
Nucleic acids research 2023 Nov 10;51(20):10970-10991
Nucleic acids research 2023 Nov 10;51(20):10970-10991
MAGL inhibition relieves synovial inflammation and pain via regulating NOX4-Nrf2 redox balance in osteoarthritis.
Li X, Tao H, Zhou J, Zhang L, Shi Y, Zhang C, Sun W, Chu M, Chen K, Gu C, Yang X, Geng D, Hao Y
Free radical biology & medicine 2023 Nov 1;208:13-25
Free radical biology & medicine 2023 Nov 1;208:13-25
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Wang P, Yang C, Lu J, Ren Y, Goltzman D, Miao D
Journal of orthopaedic translation 2023 May;40:13-26
Journal of orthopaedic translation 2023 May;40:13-26
Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.
Huang L, Liu B, Yu XW, Pan GQ, Xu JY, Yan D, Wang YL, Guo QN
Environmental science and pollution research international 2023 May;30(22):62201-62212
Environmental science and pollution research international 2023 May;30(22):62201-62212
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Zhu J, Sun R, Yan C, Sun K, Gao L, Zheng B, Shi J
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1196-1214
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1196-1214
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Yu Y, Xia LK, Di Y, Nie QZ, Chen XL
Neural regeneration research 2023 May;18(5):1132-1138
Neural regeneration research 2023 May;18(5):1132-1138
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949
Environment international 2023 May;175:107949
Interleukin-37 ameliorates atherosclerosis by regulating autophagy-mediated endothelial cell apoptosis and inflammation.
Xiao S, Song X, Zheng M, Cao X, Ai G, Li B, Zhao G, Yuan H
International immunopharmacology 2023 May;118:110098
International immunopharmacology 2023 May;118:110098
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
Li J, Wang H, Liu D, Li X, He L, Pan J, Shen Q, Peng Y
Brain, behavior, and immunity 2023 May;110:60-79
Brain, behavior, and immunity 2023 May;110:60-79
Sema3G activates YAP and promotes VSMCs proliferation and migration via Nrp2/PlexinA1.
Luo XY, Fu X, Liu F, Luo JY, Chen AF
Cellular signalling 2023 May;105:110613
Cellular signalling 2023 May;105:110613
SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis.
Jiao Z, Chai H, Wang S, Sun C, Huang Q, Xu W
Journal of molecular medicine (Berlin, Germany) 2023 May;101(5):607-620
Journal of molecular medicine (Berlin, Germany) 2023 May;101(5):607-620
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice.
Zhu Q, Zhou Q, Luo XL, Zhang XJ, Li SY
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023 May 1;27(3):221-230
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023 May 1;27(3):221-230
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.
Fan HX, Sheng S, Li DD, Li JJ, Wang GQ, Zhang F
Bioengineering & translational medicine 2023 Mar;8(2):e10455
Bioengineering & translational medicine 2023 Mar;8(2):e10455
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
Xie Z, Wu X, Cheng R, Huang J, Wang X, Shi Q, Xu B, Paulus YM, Yuan S, Liu Q
Experimental eye research 2023 Mar;228:109388
Experimental eye research 2023 Mar;228:109388
Protective effect of HDACIs in improves survival and organ injury after CLP-induced sepsis.
Niu K, Qu S, Yang L, Zhang H, Yuan J, Fan H, Li X, Tao K
Surgery open science 2023 Mar;12:35-42
Surgery open science 2023 Mar;12:35-42
Protective effecs of baicalin magnesium on non-alcoholic steatohepatitis rats are based on inhibiting NLRP3/Caspase-1/IL-1β signaling pathway.
Guan X, Shen S, Liu J, Song H, Chang J, Mao X, Song J, Zhang L, Liu C
BMC complementary medicine and therapies 2023 Mar 6;23(1):72
BMC complementary medicine and therapies 2023 Mar 6;23(1):72
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Luo D, Ye W, Chen L, Yuan X, Zhang Y, Chen C, Jin X, Zhou Y
Biomedicines 2023 Mar 21;11(3)
Biomedicines 2023 Mar 21;11(3)
Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages.
Wu H, Lin T, Chen Y, Chen F, Zhang S, Pang H, Huang L, Yu C, Wang G, Wu C
Molecules (Basel, Switzerland) 2023 Mar 20;28(6)
Molecules (Basel, Switzerland) 2023 Mar 20;28(6)
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
Peng S, Yu Y, Li J, Jiang D, Xu G, Wu L, Hu J
Aging 2023 Mar 17;15(6):1977-2004
Aging 2023 Mar 17;15(6):1977-2004
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Ouyang S, Wang X, Chen Y, Deng L, Yang X, Hu S, Wu S
Neuroscience letters 2023 Mar 16;799:137104
Neuroscience letters 2023 Mar 16;799:137104
Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases.
Chuang KC, Lai YW, Ko CH, Yen CC, Chen HL, Lan YW, Chen CF, Chen W, Chen CM
Life sciences 2023 Mar 15;317:121411
Life sciences 2023 Mar 15;317:121411
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Mao LR, Du JP, Wang XC, Xu LF, Zhang YP, Sun QS, Shi ZL, Xing YR, Su YX, Wang SJ, Wang J, Ma JL, Zhang JY
ACS infectious diseases 2023 Mar 10;9(3):593-608
ACS infectious diseases 2023 Mar 10;9(3):593-608
Ring finger protein 10 improves pirarubicin-induced cardiac inflammation by regulating the AP-1/Meox2 signaling pathway.
Duan L, Tang H, Lan Y, Shi H, Pu P, He Q
Toxicology and applied pharmacology 2023 Mar 1;462:116411
Toxicology and applied pharmacology 2023 Mar 1;462:116411
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
Xu W, Yang T, Lou X, Chen J, Wang X, Hu M, An D, Gao R, Wang J, Chen X
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
microRNA-149-5p mediates the PM(2.5)-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Li Q, Li S, Xu C, Zhao J, Hou L, Jiang F, Zhu Z, Wang Y, Tian L
Cell biology and toxicology 2023 Jun;39(3):703-717
Cell biology and toxicology 2023 Jun;39(3):703-717
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Zhang W, Chen H, Ding L, Huang J, Zhang M, Liu Y, Ma R, Zheng S, Gong J, Piña-Crespo JC, Zhang Y
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Polystyrene microplastics mediate inflammatory responses in the chicken thymus by Nrf2/NF-κB pathway and trigger autophagy and apoptosis.
Li J, Yin K, Hou L, Zhang Y, Lu H, Ma C, Xing M
Environmental toxicology and pharmacology 2023 Jun;100:104136
Environmental toxicology and pharmacology 2023 Jun;100:104136
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Ding Q, Ding C, Liu X, Zheng Y, Zhao Y, Zhang S, Sun S, Peng Z, Liu W
International journal of biological macromolecules 2023 Jun 30;241:124537
International journal of biological macromolecules 2023 Jun 30;241:124537
Peptidomics Analysis Reveals the Buccal Gland of Jawless Vertebrate Lamprey as a Source of Multiple Bioactive Peptides.
Wang Y, Sun F, Wang Z, Duan X, Li Q, Pang Y, Gou M
Marine drugs 2023 Jun 29;21(7)
Marine drugs 2023 Jun 29;21(7)
A Comparative Study of Skin Changes in Different Species of Mice in Chronic Photoaging Models.
Lin M, Liu X, Wang X, Chen Y, Zhang Y, Xu J, Bu L, Zhang Y, Liang F, Zhang X, Huang B, Zhang M, Zhang L
International journal of molecular sciences 2023 Jun 28;24(13)
International journal of molecular sciences 2023 Jun 28;24(13)
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Liu MH, Lin XL, Xiao LL
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway.
Fu A, Qiao F, Feng H, Luo Q
Behavioural brain research 2023 Jul 9;449:114464
Behavioural brain research 2023 Jul 9;449:114464
Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury.
Fang A, Wang Y, Guan N, Zuo Y, Lin L, Guo B, Mo A, Wu Y, Lin X, Cai W, Chen X, Ye J, Abdelrahman Z, Li X, Zheng H, Wu Z, Jin S, Xu K, Huang Y, Gu X, Yu B, Wang X
Nature communications 2023 Jul 7;14(1):4011
Nature communications 2023 Jul 7;14(1):4011
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice.
Du J, Zhang F, Chen M, Xiao Y, Zhang L, Dong L, Dong D, Wu B
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):886-897
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):886-897
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease.
Shen ZB, Meng HW, Meng XS, Lv ZK, Fang MY, Zhang LL, Lv ZL, Li MS, Liu AK, Han JH, Li QS, Duan YJ
European journal of medicinal chemistry 2023 Jul 5;255:115417
European journal of medicinal chemistry 2023 Jul 5;255:115417
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Song D, Zhang A, Hu X, Zeng M, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation.
Xu SY, Jia JQ, Sun M, Bao XY, Xia SN, Shu S, Liu PY, Ji SL, Ye L, Cao X, Xu Y
iScience 2023 Jul 21;26(7):107268
iScience 2023 Jul 21;26(7):107268
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Gegen-Qinlian decoction alleviates anxiety-like behaviors in methamphetamine-withdrawn mice by regulating Akkermansia and metabolism in the colon.
Lu X, Fan Y, Peng Y, Pan W, Du D, Xu X, Li N, He T, Nie J, Shi P, Ge F, Liu D, Chen Y, Guan X
Chinese medicine 2023 Jul 16;18(1):85
Chinese medicine 2023 Jul 16;18(1):85
ONO-2506 Can Delay Levodopa-induced Dyskinesia in the Early Stage.
Yuan Y, Zhang X, Wu Y, Lian P, Cao X, Xu Y
Neuroscience 2023 Jul 15;523:61-79
Neuroscience 2023 Jul 15;523:61-79
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
Xu W, Yuan Y, Tian Y, Cheng C, Chen Y, Zeng L, Yuan Y, Li D, Zheng L, Luo T
Journal of hazardous materials 2023 Jul 15;454:131470
Journal of hazardous materials 2023 Jul 15;454:131470
A COMPARATIVE ANALYSIS TO DETERMINE THE OPTIMUM HISTONE DEACETYLASE INHIBITORS AND ADMINISTRATION ROUTE FOR IMPROVING SURVIVAL AND ORGAN INJURY IN RATS AFTER HEMORRHAGIC SHOCK.
Niu K, Yang L, Song W, Liu Z, Yuan J, Zhang H, Zhang W, Wang J, Tao K
Shock (Augusta, Ga.) 2023 Jul 1;60(1):75-83
Shock (Augusta, Ga.) 2023 Jul 1;60(1):75-83
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats.
Wang C, Tang H, Wang Y, Chang Y, Wu YJ, Wang B, Sun W, Xiao F, Wei W
Acta pharmacologica Sinica 2023 Jan;44(1):81-91
Acta pharmacologica Sinica 2023 Jan;44(1):81-91
The effect and mechanism of excessive iodine on the endothelial function of human umbilical vein endothelial cells.
Wang D, Li P, Liu L, Liu P, Zhou Z, Jin M, Li B, Li F, Chen Y, Shen H
Environmental toxicology 2023 Jan;38(1):136-145
Environmental toxicology 2023 Jan;38(1):136-145
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Chen Z, Wang Z, Liu D, Zhao X, Ning S, Liu X, Wang G, Zhang F, Luo F, Yao J, Tian X
Free radical biology & medicine 2023 Jan;194:62-70
Free radical biology & medicine 2023 Jan;194:62-70
Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis.
Zhang J, Lv G
Immunity, inflammation and disease 2023 Jan;11(1):e744
Immunity, inflammation and disease 2023 Jan;11(1):e744
Exosomes From Adipose-Derived Stem Cells Suppress the Progression of Chronic Endometritis.
Wang B, Li L, Yu R
Cell transplantation 2023 Jan-Dec;32:9636897231173736
Cell transplantation 2023 Jan-Dec;32:9636897231173736
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Fan S, Weixuan W, Han H, Liansheng Z, Gang L, Jierui W, Yanshu Z
Chemico-biological interactions 2023 Jan 25;370:110310
Chemico-biological interactions 2023 Jan 25;370:110310
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
Chen H, Tu M, Liu S, Wen Y, Chen L
International journal of molecular sciences 2023 Jan 25;24(3)
International journal of molecular sciences 2023 Jan 25;24(3)
Determination of the Anti-Oxidative Stress Mechanism of Isodon suzhouensis Leaves by Employing Bioinformatic and Novel Research Technology.
Wang W, Li H, Lv J, Khan GJ, Duan H, Zhu J, Bao N, Zhai K, Xue Z
ACS omega 2023 Jan 24;8(3):3520-3529
ACS omega 2023 Jan 24;8(3):3520-3529
Ulinastatin ameliorates preeclampsia induced by N(gamma)-nitro-l-arginine methyl ester in a rat model via inhibition of the systemic and placental inflammatory response.
Yu Z, Liu Y, Zhang Y, Cui J, Dong Y, Zhang L, Liu P, Hao Y, Xu Y, Wang J
Journal of hypertension 2023 Jan 1;41(1):150-158
Journal of hypertension 2023 Jan 1;41(1):150-158
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Yang J, Han F, Wu G, Dong Y, Su H, Xu J, Li J
Digestive diseases and sciences 2023 Feb;68(2):478-486
Digestive diseases and sciences 2023 Feb;68(2):478-486
Crocetin confers neuroprotection and is anti-inflammatory in rats with induced glaucoma.
Li Q, Feng P, Lin S, Xu Z, Zhao J, Chen Z, Luo Z, Tao Y, Chen S, Wang P
Molecular biology reports 2023 Feb;50(2):1321-1331
Molecular biology reports 2023 Feb;50(2):1321-1331
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Li Y, Yang L, Li J, Gao W, Zhao Z, Dong K, Duan W, Dai B, Guo R
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Li Y, Jin T, Liu N, Wang J, Qin Z, Yin S, Zhang Y, Fu Z, Wu Y, Wang Y, Liu Y, Yang M, Pang A, Sun J, Wang Y, Yang X
Journal of neuroinflammation 2023 Feb 28;20(1):53
Journal of neuroinflammation 2023 Feb 28;20(1):53
Acupuncture exerts preventive effects in rats of chronic unpredictable mild stress: The involvement of inflammation in amygdala and brain-spleen axis.
Chen W, Chen Y, Cheng W, Li P, Shen J, Tong T, Lai L, Yan S, Huang Z, Li J, Huang S, Meng X
Biochemical and biophysical research communications 2023 Feb 26;646:86-95
Biochemical and biophysical research communications 2023 Feb 26;646:86-95
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway.
Liu C, Yao K, Tian Q, Guo Y, Wang G, He P, Wang J, Wang J, Zhang Z, Li M
Redox biology 2023 Dec;68:102960
Redox biology 2023 Dec;68:102960
PM(2.5) exposure increases dry eye disease risks through corneal epithelial inflammation and mitochondrial dysfunctions.
Yu D, Cai W, Shen T, Wu Y, Ren C, Li T, Hu C, Zhu M, Yu J
Cell biology and toxicology 2023 Dec;39(6):2615-2630
Cell biology and toxicology 2023 Dec;39(6):2615-2630
Collagen-EGCG Combination Synergistically Prevents UVB-Induced Skin Photoaging in Nude Mice.
Fan Z, Zhou Y, Gan B, Li Y, Chen H, Peng X, Zhou Y
Macromolecular bioscience 2023 Dec;23(12):e2300251
Macromolecular bioscience 2023 Dec;23(12):e2300251
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Wen W, Xu Y, Qian W, Huang L, Gong J, Li Y, Zhu W, Guo Z
Gut microbes 2023 Dec;15(2):2265578
Gut microbes 2023 Dec;15(2):2265578
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
Wei X, Shen Z, Zhu M, Fang M, Wang S, Zhang T, Zhang B, Yang X, Lv Z, Duan Y, Jiang M, Ma C, Li Q, Chen Y
International immunopharmacology 2023 Dec;125(Pt B):111198
International immunopharmacology 2023 Dec;125(Pt B):111198
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
Wang X, Gao F, Cheng C, Zhang Y
Functional & integrative genomics 2023 Dec 8;24(1):1
Functional & integrative genomics 2023 Dec 8;24(1):1
Ethanol extract of Paridis rhizoma attenuates carrageenan-induced paw swelling in rats by inhibiting the production of inflammatory factors.
Xiang L, Huang Q, Chen T, He Q, Yao H, Gao Y
BMC complementary medicine and therapies 2023 Dec 4;23(1):437
BMC complementary medicine and therapies 2023 Dec 4;23(1):437
Prolonged Antibiotic Use in a Preclinical Model of Gulf War Chronic Multisymptom-Illness Causes Renal Fibrosis-like Pathology via Increased micro-RNA 21-Induced PTEN Inhibition That Is Correlated with Low Host Lachnospiraceae Abundance.
Trivedi A, Bose D, Saha P, Roy S, More M, Skupsky J, Klimas NG, Chatterjee S
Cells 2023 Dec 27;13(1)
Cells 2023 Dec 27;13(1)
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
Shen T, Lin R, Hu C, Yu D, Ren C, Li T, Zhu M, Wan Z, Su T, Wu Y, Cai W, Yu J
Journal of neuroinflammation 2023 Dec 21;20(1):308
Journal of neuroinflammation 2023 Dec 21;20(1):308
Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model.
Alsadi N, Yasavoli-Sharahi H, Mueller R, Cuenin C, Chung F, Herceg Z, Matar C
Antioxidants (Basel, Switzerland) 2023 Dec 21;13(1)
Antioxidants (Basel, Switzerland) 2023 Dec 21;13(1)
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Sun QY, Wang XY, Huang ZP, Song J, Zheng ED, Gong FH, Huang XW
World journal of diabetes 2023 Dec 15;14(12):1824-1838
World journal of diabetes 2023 Dec 15;14(12):1824-1838
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Bai J, Qian B, Cai T, Chen Y, Li T, Cheng Y, Wu Z, Liu C, Ye M, Du Y, Fu W
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Fabrication of an Adhesive Small Intestinal Submucosa Acellular Matrix Hydrogel for Accelerating Diabetic Wound Healing.
Chen Y, Hu M, Hu H, Ji S, Huang L, Wei W, Zhao K, Teng C
ACS omega 2023 Dec 12;8(49):46653-46662
ACS omega 2023 Dec 12;8(49):46653-46662
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification.
Gao J, Su G, Chen W, Wu Q, Liu J, Liu J, Chai M, Dong Y, Wang H, Chen L, Zhang Z, Wang M
Clinical and experimental pharmacology & physiology 2023 Aug;50(8):647-663
Clinical and experimental pharmacology & physiology 2023 Aug;50(8):647-663
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
He JY, Li DD, Wen Q, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
Li J, Han J, Shi Y, Liu M
Experimental eye research 2023 Aug;233:109539
Experimental eye research 2023 Aug;233:109539
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
Wu K, Liu YY, Shao S, Song W, Chen XH, Dong YT, Zhang YM
Brain, behavior, and immunity 2023 Aug;112:96-117
Brain, behavior, and immunity 2023 Aug;112:96-117
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Research square 2023 Aug 9;
Research square 2023 Aug 9;
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
Wang H, Tang Q, Lu Y, Chen C, Zhao YL, Xu T, Yang CW, Chen XQ
International journal of pharmaceutics 2023 Aug 25;643:123283
International journal of pharmaceutics 2023 Aug 25;643:123283
circIFNGR2 regulating ankylosing spondylitis-associated inflammation through macrophage polarization.
Song M, Wang X, Gao J, Jiang W, Bi E, An T, Wang T, Chen Z, Liu W, Shi Z, Xiao J, Zhang C
iScience 2023 Aug 18;26(8):107325
iScience 2023 Aug 18;26(8):107325
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Yang X, Wang Q, Zhang X, Li L, Cao X, Zhou L, Huang Y, Sun G, Chen Y
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Up-regulation of PPAR-γ involved in the therapeutic effect of icariin on cigarette smoke-induced inflammation.
Li Q, Zhang H, Yan X, Zhao Z, Qiu J, Hu L, Jiang S, Kong Q, Sun J, Li L
Pulmonary pharmacology & therapeutics 2023 Apr;79:102197
Pulmonary pharmacology & therapeutics 2023 Apr;79:102197
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Xie Z, Wu XJ, Cheng RW, Cui JH, Yuan ST, Zhou JW, Liu QH
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
An D, Qi X, Li K, Xu W, Wang Y, Chen X, Sha S, Wu C, Du Y, Chen L
Cellular and molecular neurobiology 2023 Apr;43(3):1283-1300
Cellular and molecular neurobiology 2023 Apr;43(3):1283-1300
Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.
Wang P, Zhu G, Wu Q, Shen L, Liu D, Wang Z, Wang W, Ren Z, Jia Y, Liu M, Xue Y, Ji D, Hu Y, Yu Y, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22834
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22834
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
Zhao J, Lu Q, Yang Z, Sun B, Zhu J, Zhang H, Yang C, Yi S, Dong X
International urogynecology journal 2023 Apr;34(4):843-851
International urogynecology journal 2023 Apr;34(4):843-851
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Liu YL, Wang SR, Ma JX, Yu LH, Jia GW
Neural regeneration research 2023 Apr;18(4):825-831
Neural regeneration research 2023 Apr;18(4):825-831
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G
Genes 2023 Apr 30;14(5)
Genes 2023 Apr 30;14(5)
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Zeng S, Tao M, Yuan L, Zhang L, Luo X
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
[Berberine inhibits autophagy and promotes apoptosis of fibroblast-like synovial cells from rheumatoid arthritis patients through the ROS/mTOR signaling pathway].
Zong S, Zhou J, Cai W, Yu Y, Wang Y, Song Y, Cheng J, Li Y, Gao Y, Wu B, Xian H, Wei F
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):552-559
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):552-559
Diacylated anthocyanins from purple sweet potato (Ipomoeabatatas L.) attenuate hyperglycemia and hyperuricemia in mice induced by a high-fructose/high-fat diet.
Shen L, Yang Y, Zhang J, Feng L, Zhou Q
Journal of Zhejiang University. Science. B 2023 Apr 15;24(7):587-601
Journal of Zhejiang University. Science. B 2023 Apr 15;24(7):587-601
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
The Role of the Superior Cervical Sympathetic Ganglion in Ischemia Reperfusion-Induced Acute Kidney Injury in Rats.
Zhang W, Li Z, Li Z, Sun T, He Z, Manyande A, Xu W, Xiang H
Frontiers in medicine 2022;9:792000
Frontiers in medicine 2022;9:792000
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
Gong X, Liu L, Li X, Xiong J, Xu J, Mao D, Liu L
Frontiers in nutrition 2022;9:1028459
Frontiers in nutrition 2022;9:1028459
ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice.
Li H, Zhang P, Lin H, Gao H, Yin J
Disease markers 2022;2022:8583674
Disease markers 2022;2022:8583674
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
Huang YB, Jiang L, Liu XQ, Wang X, Gao L, Zeng HX, Zhu W, Hu XR, Wu YG
Oxidative medicine and cellular longevity 2022;2022:4776243
Oxidative medicine and cellular longevity 2022;2022:4776243
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Chen B, Liang S, Guo H, Xu L, Li J, Peng J
Genetics research 2022;2022:3154827
Genetics research 2022;2022:3154827
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Liu WZ, Ma ZJ, Kang JH, Lin AX, Wang ZH, Chen HW, Guo XD, He XG, Kang XW
Mediators of inflammation 2022;2022:2579003
Mediators of inflammation 2022;2022:2579003
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
Fan R, Dai F, Zhang C, Zhou L, Qiu X, Li Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Xing B, Lan H, Li H
Oxidative medicine and cellular longevity 2022;2022:1881519
Oxidative medicine and cellular longevity 2022;2022:1881519
Acyloxyacyl hydrolase regulates microglia-mediated pelvic pain.
Rahman-Enyart A, Yaggie RE, Bollinger JL, Arvanitis C, Winter DR, Schaeffer AJ, Klumpp DJ
PloS one 2022;17(8):e0269140
PloS one 2022;17(8):e0269140
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Rong ZJ, Cai HH, Wang H, Liu GH, Zhang ZW, Chen M, Huang YL
Frontiers in cellular neuroscience 2022;16:872935
Frontiers in cellular neuroscience 2022;16:872935
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Yang QQ, Li HN, Xia YT, Tian X, Feng F, Yang J, Xu YL, Guo J, Li XQ, Wang JY, Zeng XY
Frontiers in molecular neuroscience 2022;15:820664
Frontiers in molecular neuroscience 2022;15:820664
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Hao M, Ding C, Sun S, Peng X, Liu W
Journal of inflammation research 2022;15:4921-4938
Journal of inflammation research 2022;15:4921-4938
PTBP-1 and TNF-α/NF-κB are involved in repair mechanisms of human umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury.
Cao H, Ji X, Wang Q, Guan X, Wei W, Li Y, Zou W, Liu J
American journal of translational research 2022;14(7):4443-4456
American journal of translational research 2022;14(7):4443-4456
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Shi L, Zhao Y, Feng C, Miao F, Dong L, Wang T, Stalin A, Zhang J, Tu J, Liu K, Sun W, Wu J
Frontiers in pharmacology 2022;13:967164
Frontiers in pharmacology 2022;13:967164
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis.
Dong C, Chen W, Zou L, Liu B, Deng K, Guo D, Wang P, Chen H, Wang H, Wang J
Frontiers in microbiology 2022;13:963901
Frontiers in microbiology 2022;13:963901
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promoted Wound Healing by Regulating PI3K/AKT/mTOR and SIRT1/NF-κB Pathways.
Hao M, Peng X, Sun S, Ding C, Liu W
Frontiers in pharmacology 2022;13:913408
Frontiers in pharmacology 2022;13:913408
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Chen Y, Li T, Tan P, Shi H, Cheng Y, Cai T, Bai J, Du Y, Fu W
Frontiers in pharmacology 2022;13:857015
Frontiers in pharmacology 2022;13:857015
Indole-3-Carbinol Selectively Prevents Chronic Stress-Induced Depression-but not Anxiety-Like Behaviors via Suppressing Pro-Inflammatory Cytokine Production and Oxido-Nitrosative Stress in the Brain.
Pan S, Ma Y, Yang R, Lu X, You Q, Ye T, Huang C
Frontiers in pharmacology 2022;13:829966
Frontiers in pharmacology 2022;13:829966
Neutrophil Extracellular Traps Regulate HMGB1 Translocation and Kupffer Cell M1 Polarization During Acute Liver Transplantation Rejection.
Liu Y, Pu X, Qin X, Gong J, Huang Z, Luo Y, Mou T, Zhou B, Shen A, Wu Z
Frontiers in immunology 2022;13:823511
Frontiers in immunology 2022;13:823511
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
An Integrative Pharmacology Model for Decoding the Underlying Therapeutic Mechanisms of Ermiao Powder for Rheumatoid Arthritis.
Wu J, Wang K, Liu Q, Li Y, Huang Y, Liu Y, Cai J, Yin C, Li X, Yu H, Meng W, Wang H, Lu A, Li Y, Guan D
Frontiers in pharmacology 2022;13:801350
Frontiers in pharmacology 2022;13:801350
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Zhang KK, Chen LJ, Li JH, Liu JL, Wang LB, Xu LL, Yang JZ, Li XW, Xie XL, Wang Q
Frontiers in microbiology 2022;13:755189
Frontiers in microbiology 2022;13:755189
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Lu R, He Z, Zhang W, Wang Y, Cheng P, Lv Z, Yuan X, Guo F, You H, Chen AM, Hu W
Frontiers in endocrinology 2022;13:1060721
Frontiers in endocrinology 2022;13:1060721
Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p.
Song JJ, Li H, Wang N, Zhou XY, Liu Y, Zhang Z, Feng Q, Chen YL, Liu D, Liang J, Ma XY, Wen XR, Fu YY
Frontiers in pharmacology 2022;13:1044375
Frontiers in pharmacology 2022;13:1044375
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Liao YF, Luo FL, Tang SS, Huang JW, Yang Y, Wang S, Jiang TY, Man Q, Liu S, Wu YY
Frontiers in pharmacology 2022;13:1014160
Frontiers in pharmacology 2022;13:1014160
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Wang J, Yang X, Zeng W, Zhang X, Yang X, Xu Y, Liu K, Zhang Z, Xu Y, Cao X
Journal of Parkinson's disease 2022;12(7):2097-2116
Journal of Parkinson's disease 2022;12(7):2097-2116
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
Wang FF, Zhao PY, He XJ, Jiang K, Wang TS, Xiao JW, Sun DB, Guo DH
Frontiers in cellular and infection microbiology 2022;12:827750
Frontiers in cellular and infection microbiology 2022;12:827750
New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice.
Du Y, Zhong Y, Ding R, Wang X, Xia F, Zhang Q, Peng Q
Frontiers in cellular and infection microbiology 2022;12:1068324
Frontiers in cellular and infection microbiology 2022;12:1068324
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Zhou Y, Lu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Khodayari N, Oshins R, Mehrad B, Lascano JE, Qiang X, West JR, Holliday LS, Lee J, Wiesemann G, Eydgahi S, Brantly M
Respiratory research 2022 Sep 6;23(1):232
Respiratory research 2022 Sep 6;23(1):232
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Hu S, Shen P, Chen B, Tian SW, You Y
Neuroscience letters 2022 Sep 25;788:136850
Neuroscience letters 2022 Sep 25;788:136850
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Zhao X, Xia Z, Wang Z, Zhou M, Qiu X, Wang C, Xu T, Fang Q, Ming Z, Dong H
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
Jiang Z, Jiang C, Jin L, Chen Z, Feng Z, Jiang X, Cao Y
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2022 Oct;40(10):2350-2361
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2022 Oct;40(10):2350-2361
The protective mechanism of folic acid on hyperhomocysteinemia-related arterial injury in spontaneously hypertensive rats: Folic acid against arterial inflammation.
Zhang L, Li Z, Xing C, Ma X, Xu R
Vascular 2022 Oct;30(5):988-998
Vascular 2022 Oct;30(5):988-998
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Yang QY, Li XW, Yang R, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
Gao N, Wang C, Yu Y, Xie L, Xing Y, Zhang Y, Wang Y, Wu J, Cai Y
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Fu C, Qiu Z, Huang Y, Lin Q, Jin L, Tu H, Ye J, Zheng C, Zhong W, Ma D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939
Bioorganic chemistry 2022 Oct;127:105939
Glycosides from Buyang Huanwu Decoction inhibit atherosclerotic inflammation via JAK/STAT signaling pathway.
Fu X, Sun Z, Long Q, Tan W, Ding H, Liu X, Wu L, Wang Y, Zhang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154385
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154385
Ethanol extracts of Rhaponticum uniflorum (L.) DC inflorescence ameliorate LPS-mediated acute lung injury by alleviating inflammatory responses via the Nrf2/HO-1 signaling pathway.
Zhen D, Liu C, Huang T, Fu D, Bai X, Ma Q, Jiang M, Gong G
Journal of ethnopharmacology 2022 Oct 5;296:115497
Journal of ethnopharmacology 2022 Oct 5;296:115497
Treadmill Exercise Modulates Intestinal Microbes and Suppresses LPS Displacement to Alleviate Neuroinflammation in the Brains of APP/PS1 Mice.
Yuan S, Yang J, Jian Y, Lei Y, Yao S, Hu Z, Liu X, Tang C, Liu W
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
Hypoxic preconditioned aged BMSCs accelerates MI injury repair by modulating inflammation, oxidative stress and apoptosis.
Song H, Li B, Guo R, He S, Peng Z, Qu J, Zhao Y, Zhai X, Yin W, Yang K, Fan X, Zhang J, Tan J, Liu Y, Xie J, Xu J
Biochemical and biophysical research communications 2022 Oct 30;627:45-51
Biochemical and biophysical research communications 2022 Oct 30;627:45-51
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Yang J, Miao RR, Li YN, Pan T, Wu SH, Qu XJ, Cui SX
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Lin S, Li Q, Xu Z, Chen Z, Tao Y, Tong Y, Wang T, Chen S, Wang P
Psychopharmacology 2022 Nov;239(11):3657-3677
Psychopharmacology 2022 Nov;239(11):3657-3677
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Zhan L, Zheng J, Meng J, Fu D, Pang L, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Upregulation of TACAN in the trigeminal ganglion affects pain transduction in acute pulpitis.
Shang Y, Li Y, Yang Z, Zhou Z
Archives of oral biology 2022 Nov;143:105530
Archives of oral biology 2022 Nov;143:105530
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Yi Y, Yang N, Yang Z, Tao X, Li Y
Orthopaedic surgery 2022 Nov;14(11):3078-3091
Orthopaedic surgery 2022 Nov;14(11):3078-3091
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C
Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Zhan H, Pu Q, Long X, Lu W, Wang G, Meng F, Liao Z, Lan X, Chen M
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Qu D, Ye Z, Zhang W, Dai B, Chen G, Wang L, Shao X, Xiang A, Lu Z, Shi J
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
Zhou P, Lai J, Li Y, Deng J, Zhao C, Huang Q, Yang F, Yang S, Wu Y, Tang X, Huang F, Wang L, Huang X, Zou W, Wu J
International journal of molecular sciences 2022 Nov 14;23(22)
International journal of molecular sciences 2022 Nov 14;23(22)
Single Cell Proteomics Profiling Reveals That Embryo-Secreted TNF-α Plays a Critical Role During Embryo Implantation to the Endometrium.
Lv J, Shan X, Yang H, Wen Y, Zhang X, Chen H, Li H, Tian D, Wang CC, Zhang R, Li TC, Zhang X, Zhao X, Lu Y, Qin L, Zhu M, Xu W
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1608-1617
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1608-1617
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Zhu W, Peng F, Cui X, Li J, Sun C
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
P38α deficiency in macrophages ameliorates murine experimental colitis by regulating inflammation and immune process.
Chen W, Liang R, Yi Y, Zhu J, Zhang J
Pathology, research and practice 2022 May;233:153881
Pathology, research and practice 2022 May;233:153881
Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats.
Ji NN, Meng QX, Wang Y, Zhou ZM, Song Y, Hua R, Zhang YM
Neurobiology of stress 2022 May;18:100449
Neurobiology of stress 2022 May;18:100449
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Mao L, Xu L, Wang X, Xing Y, Wang J, Zhang Y, Yuan W, Du J, Shi Z, Ma J, Zhang J, Zhang X, Wang X
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Shi P, Zhao T, Wang W, Peng F, Wang T, Jia Y, Zou L, Wang P, Yang S, Fan Y, Zong J, Qu X, Wang S
Nutrition & metabolism 2022 May 18;19(1):36
Nutrition & metabolism 2022 May 18;19(1):36
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Xiong T, Zheng X, Zhang K, Wu H, Dong Y, Zhou F, Cheng B, Li L, Xu W, Su J, Huang J, Jiang Z, Li B, Zhang B, Lv G, Chen S
Journal of ethnopharmacology 2022 May 10;289:115001
Journal of ethnopharmacology 2022 May 10;289:115001
Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway.
Li G, Duan L, Yang F, Yang L, Deng Y, Yu Y, Xu Y, Zhang Y
Phytotherapy research : PTR 2022 Mar;36(3):1326-1337
Phytotherapy research : PTR 2022 Mar;36(3):1326-1337
The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.
Jiang ZY, Liu MZ, Fu ZH, Liao XC, Xu B, Shi LL, Li JQ, Guo GH
Bioengineered 2022 Mar;13(3):4978-4990
Bioengineered 2022 Mar;13(3):4978-4990
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Wang G, Li X, Li N, Wang X, He S, Li W, Fan W, Li R, Liu J, Hou S
Redox biology 2022 Jun;52:102297
Redox biology 2022 Jun;52:102297
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Yang T, Ma X, Wang R, Liu H, Wei S, Jing M, Li H, Zhao Y
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Zhao J, Chen S, Yang C, Zhou M, Yang T, Sun B, Zhu J, Zhang H, Lu Q, Li L, Yang Z, Song B, Shen W, Yi S, Dai S
Biochemical pharmacology 2022 Jun;200:115047
Biochemical pharmacology 2022 Jun;200:115047
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Cai J, Liang J, Zhang Y, Shen L, Lin H, Hu T, Zhan S, Xie M, Liang S, Xian M, Wang S
Pharmacological research 2022 Jun;180:106230
Pharmacological research 2022 Jun;180:106230
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH
The Journal of nutritional biochemistry 2022 Jun;104:108974
The Journal of nutritional biochemistry 2022 Jun;104:108974
Blockage of transient receptor potential vanilloid 4 prevents postoperative atrial fibrillation by inhibiting NLRP3-inflammasome in sterile pericarditis mice.
Yang S, Zhao Z, Zhao N, Liao J, Lu Y, Zhang S, Lu K, Wu Y, Wu Q, Dong Q, Chen L, Du Y
Cell calcium 2022 Jun;104:102590
Cell calcium 2022 Jun;104:102590
Alterations in the jejunal microbiota and fecal metabolite profiles of rabbits infected with Eimeria intestinalis.
Yuan X, Liu J, Hu X, Yang S, Zhong S, Yang T, Zhou Y, Zhao G, Jiang Y, Li Y
Parasites & vectors 2022 Jun 26;15(1):231
Parasites & vectors 2022 Jun 26;15(1):231
L-Se-methylselenocysteine loaded mucoadhesive thermogel for effective treatment of Vulvar candidiasis.
Yang X, Wang M, Kang X, Mo F, Si P, Ma J, Zhang P, Zheng S, Li J, Wang Y, Li Q, Zhang J
International journal of pharmaceutics 2022 Jun 25;622:121851
International journal of pharmaceutics 2022 Jun 25;622:121851
Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism.
Yan S, Chen J, Zhu L, Guo T, Qin D, Hu Z, Han S, Zhou Y, Akan OD, Wang J, Luo F, Lin Q
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6429-6443
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6429-6443
Acrylonitrile exposure triggers ovarian inflammation and decreases oocyte quality probably via mitochondrial dysfunction induced apoptosis in mice.
Luo YS, He QK, Sun MX, Qiao FX, Liu YC, Xu CL, Xu ZR, Zhao SC, Wang HL, Qi ZQ, Liu Y
Chemico-biological interactions 2022 Jun 1;360:109934
Chemico-biological interactions 2022 Jun 1;360:109934
2-undecanone protects against fine particles-induced heart inflammation via modulating Nrf2/HO-1 and NF-κB pathways.
Jiao Y, Wang S, Jiang L, Sun X, Li J, Liu X, Yao X, Zhang C, Wang N, Deng H, Yang G
Environmental toxicology 2022 Jul;37(7):1642-1652
Environmental toxicology 2022 Jul;37(7):1642-1652
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Yang RC, Huang K, Zhang HP, Li L, Tan C, Chen HC, Jin ML, Wang XR
BMC neuroscience 2022 Jul 6;23(1):43
BMC neuroscience 2022 Jul 6;23(1):43
Gout-associated uric acid crystals induce tophi ulcerations and impair wound healing in a novel gouty ulcer model.
Bao W, Xue Y, Cheng X, Wang P, Yin B, Su Y, Jia C
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Jan;30(1):132-139
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Jan;30(1):132-139
Pharmacological inhibition of epidermal growth factor receptor attenuates intracranial aneurysm formation by modulating the phenotype of vascular smooth muscle cells.
Luo Y, Tang H, Zhang Z, Zhao R, Wang C, Hou W, Huang Q, Liu J
CNS neuroscience & therapeutics 2022 Jan;28(1):64-76
CNS neuroscience & therapeutics 2022 Jan;28(1):64-76
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Wang X, Du H, Li X
International immunopharmacology 2022 Jan;102:108413
International immunopharmacology 2022 Jan;102:108413
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Mu N, Wang H, Chen D, Wang F, Ji L, Zhang C, Li M, Lu P
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Li K, Yan G, Huang H, Zheng M, Ma K, Cui X, Lu D, Zheng L, Zhu B, Cheng J, Zhao J
Journal of nanobiotechnology 2022 Jan 20;20(1):38
Journal of nanobiotechnology 2022 Jan 20;20(1):38
tRNA-derived fragment TRF365 regulates the metabolism of anterior cruciate ligament cells by targeting IKBKB.
Long D, Xu Y, Mao G, Xin R, Deng Z, Liao H, Li Z, Yang Z, Yu B, Yang Z, He A, Zhang Z, Kang Y
Cell death discovery 2022 Jan 10;8(1):19
Cell death discovery 2022 Jan 10;8(1):19
Inhibition of Noncanonical Ca(2+) Oscillation/Calcineurin/GSK-3β Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.
Gao T, Gao C, Liu Z, Wang Y, Jia X, Tian H, Lu Q, Guo L
Neurochemical research 2022 Feb;47(2):264-278
Neurochemical research 2022 Feb;47(2):264-278
C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis.
Kuwahara M, Akasaki Y, Kurakazu I, Sueishi T, Toya M, Uchida T, Tsutsui T, Hirose R, Tsushima H, Teramura T, Nakashima Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22145
Injectable gelatin/oxidized dextran hydrogel loaded with apocynin for skin tissue regeneration.
Guan S, Zhang K, Cui L, Liang J, Li J, Guan F
Biomaterials advances 2022 Feb;133:112604
Biomaterials advances 2022 Feb;133:112604
Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice.
Song H, Zhang X, Zhai R, Liang H, Song G, Yuan Y, Xu Y, Yan Y, Qiu L, Sun T
Bioengineered 2022 Feb;13(2):4598-4609
Bioengineered 2022 Feb;13(2):4598-4609
Placental trophoblast-specific overexpression of chemerin induces preeclampsia-like symptoms.
Tan L, Chen Z, Sun F, Zhou Z, Zhang B, Wang B, Chen J, Li M, Xiao T, Neuman RI, Niu J, Verdonk K, Lu X, Zhang JV, Danser AHJ, Yang Q, Fan X
Clinical science (London, England : 1979) 2022 Feb 25;136(4):257-272
Clinical science (London, England : 1979) 2022 Feb 25;136(4):257-272
Combined royal jelly 10-hydroxydecanoic acid and aspirin has a synergistic effect against memory deficit and neuroinflammation.
You M, Wang K, Pan Y, Tao L, Ma Q, Zhang G, Hu F
Food & function 2022 Feb 21;13(4):2336-2353
Food & function 2022 Feb 21;13(4):2336-2353
Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways.
Zheng P, Huang Z, Tong DC, Zhou Q, Tian S, Chen BW, Ning DM, Guo YM, Zhu WH, Long Y, Xiao W, Deng Z, Lei YC, Tian XF
World journal of gastrointestinal oncology 2022 Feb 15;14(2):450-477
World journal of gastrointestinal oncology 2022 Feb 15;14(2):450-477
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Xia Y, Lu YW, Hao RJ, Yu GR
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
Luo P, Chen J, Zhang Q, Xia F, Wang C, Bai Y, Tang H, Liu D, Gu L, Du Q, Xiao W, Yang C, Wang J
Precision clinical medicine 2022 Dec;5(4):pbac023
Precision clinical medicine 2022 Dec;5(4):pbac023
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Lu S, Yuan Y, Chen F, Zheng Y, Li C, Cao J, Xia G, Liu Z, Shen X, He Y, Zhou D, Zhu K
Journal of food biochemistry 2022 Dec;46(12):e14392
Journal of food biochemistry 2022 Dec;46(12):e14392
The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1.
Zhao Y, Xie Y, Li X, Song J, Guo M, Xian D, Zhong J
Redox report : communications in free radical research 2022 Dec;27(1):200-211
Redox report : communications in free radical research 2022 Dec;27(1):200-211
A novel Atlantic salmon (Salmo salar) bone collagen peptide delays osteoarthritis development by inhibiting cartilage matrix degradation and anti-inflammatory.
Luo X, Liu W, Zhao M, Liu T, Xiong F, Lei L, Jia F, Feng F
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112148
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112148
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment.
Li N, Xie L, Wu Y, Wu Y, Liu Y, Gao Y, Yang J, Zhang X, Jiang L
Materials today. Bio 2022 Dec;16:100360
Materials today. Bio 2022 Dec;16:100360
Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway.
Liu Z, Zhang Z, Zou T, Fang M, Wang T, Meng H, Chen Y, Duan Y, Wei L, Han J, Li Q, Yang X
Bioorganic chemistry 2022 Dec;129:106206
Bioorganic chemistry 2022 Dec;129:106206
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Lian N, Jin H, Zhu W, Zhang C, Qi Y, Jiang M, Mao J, Lu X, Zhao F, Xi B, Qi X, Li Y
Acta histochemica 2022 Dec;124(8):151961
Acta histochemica 2022 Dec;124(8):151961
Depletion of regulatory T cells exacerbates inflammatory responses after chronic cerebral hypoperfusion in mice.
Wang Y, Wu Q, Fang Y, Song G, Xu L, Wang W, Pan D, Xie M
Molecular and cellular neurosciences 2022 Dec;123:103788
Molecular and cellular neurosciences 2022 Dec;123:103788
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sun Y, Li H, Liu L, Bai X, Wu L, Shan J, Sun X, Wang Q, Guo Y
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Freshwater Clam Extract Attenuates Indomethacin-Induced Gastric Damage In Vitro and In Vivo.
Isnain FS, Liao NC, Tsai HY, Zhao YJ, Huang CH, Hsu JL, Wardani AK, Chen YK
Foods (Basel, Switzerland) 2022 Dec 28;12(1)
Foods (Basel, Switzerland) 2022 Dec 28;12(1)
Calcium phosphate cement with icariin-loaded gelatin microspheres as a local drug delivery system for bone regeneration.
Liu N, Huang S, Guo F, Zhai S, Wang D, Li F, Liu C
Biomedical engineering online 2022 Dec 22;21(1):89
Biomedical engineering online 2022 Dec 22;21(1):89
Protective effect and mechanism of baicalin on lung inflammatory injury in BALB/cJ mice induced by PM2.5.
Deng L, Ma M, Li S, Zhou L, Ye S, Wang J, Yang Q, Xiao C
Ecotoxicology and environmental safety 2022 Dec 15;248:114329
Ecotoxicology and environmental safety 2022 Dec 15;248:114329
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
Wang Y, Xiong B, Lin H, Li Q, Yang H, Qiao Y, Li Q, Xu Z, Lyu W, Qu W, Liu W, Chen Y, Feng F, Sun H
European journal of medicinal chemistry 2022 Dec 15;244:114806
European journal of medicinal chemistry 2022 Dec 15;244:114806
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI).
Taheri S, Karaca Z, Mehmetbeyoglu E, Hamurcu Z, Yilmaz Z, Dal F, Çınar V, Ulutabanca H, Tanriverdi F, Unluhizarci K, Rassoulzadegan M, Kelestimur F
International journal of molecular sciences 2022 Dec 10;23(24)
International journal of molecular sciences 2022 Dec 10;23(24)
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Feng XW, Cheng QL, Fang L, Liu WY, Liu LW, Sun CQ, Lu ZH, Li GM, Gu RZ
Journal of food biochemistry 2022 Aug;46(8):e14162
Journal of food biochemistry 2022 Aug;46(8):e14162
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Chai H, Zhang ZH, Fang JY, She C, Geng C, Xu W
Journal of cellular and molecular medicine 2022 Aug;26(15):4371-4385
Journal of cellular and molecular medicine 2022 Aug;26(15):4371-4385
Taurine inhibits necroptosis helps to alleviate inflammatory and injury induced by Klebsiella infection.
Yin H, Wang Z, Yang S, Zheng X, Bao Y, Lin W, Huang C, Qiu L
Veterinary immunology and immunopathology 2022 Aug;250:110444
Veterinary immunology and immunopathology 2022 Aug;250:110444
Anti-Inflammatory Activity of 4-(4-(Heptyloxy)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one via Repression of MAPK/NF-κB Signaling Pathways in β-Amyloid-Induced Alzheimer's Disease Models.
An F, Xuan X, Liu Z, Bian M, Shen Q, Quan Z, Zhang G, Wei C
Molecules (Basel, Switzerland) 2022 Aug 8;27(15)
Molecules (Basel, Switzerland) 2022 Aug 8;27(15)
The effect of a chrysanthemum water extract in protecting the retina of mice from light damage.
Gong Y, Wang X, Wang Y, Hao P, Wang H, Guo Y, Zhang W
BMC complementary medicine and therapies 2022 Aug 26;22(1):224
BMC complementary medicine and therapies 2022 Aug 26;22(1):224
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.
Chen J, Luo P, Wang C, Yang C, Bai Y, He X, Zhang Q, Zhang J, Yang J, Wang S, Wang J
JCI insight 2022 Aug 22;7(16)
JCI insight 2022 Aug 22;7(16)
Chemical characteristics of Rhodiola Crenulata and its mechanism in acute mountain sickness using UHPLC-Q-TOF-MS/MS combined with network pharmacology analysis.
Ma D, Wang L, Jin Y, Gu L, Yin G, Wang J, Yu XA, Huang H, Zhang Z, Wang B, Lu Y, Bi K, Wang P, Wang T
Journal of ethnopharmacology 2022 Aug 10;294:115345
Journal of ethnopharmacology 2022 Aug 10;294:115345
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.
Chai W, Zhang J, Xiang Z, Zhang H, Mei Z, Nie H, Xu R, Zhang P
Metabolic brain disease 2022 Apr;37(4):1145-1154
Metabolic brain disease 2022 Apr;37(4):1145-1154
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain.
Peng Z, Yang F, Huang S, Tang Y, Wan L
Molecular pain 2022 Apr;18:17448069221094528
Molecular pain 2022 Apr;18:17448069221094528
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor.
Ji M, Cheng J, Zhang D
Bioengineered 2022 Apr;13(4):9628-9644
Bioengineered 2022 Apr;13(4):9628-9644
Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis.
Tai BY, Lu MK, Yang HY, Tsai CS, Lin CY
Biomedicines 2022 Apr 23;10(5)
Biomedicines 2022 Apr 23;10(5)
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
Zhang Y, Ying F, Tian X, Lei Z, Li X, Lo CY, Li J, Jiang L, Yao X
Cells 2022 Apr 22;11(9)
Cells 2022 Apr 22;11(9)
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Wu M, Cong Y, Wang K, Yu H, Zhang X, Ma M, Duan Z, Pei X
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Li Y, Chandra TP, Song X, Nie L, Liu M, Yi J, Zheng X, Chu C, Yang J
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.
Tan J, Dai A, Pan L, Zhang L, Wang Z, Ke T, Sun W, Wu Y, Ding PH, Chen L
Journal of immunology research 2021;2021:9919024
Journal of immunology research 2021;2021:9919024
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
Zhang F, Fan L, Zhang H, Huang WJ, Sun D, Pan BB, Wan X, Cao CC
Journal of immunology research 2021;2021:5521051
Journal of immunology research 2021;2021:5521051
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496
Journal of oncology 2021;2021:5170496
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Zhang H, Zhao J, Lu Q, Sun B, Liu X, Yang C, Li S, Li L, Yi S, Yang Z, Xu J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
Ke J, Zhao F, Luo Y, Deng F, Wu X
International journal of biological sciences 2021;17(8):2099-2111
International journal of biological sciences 2021;17(8):2099-2111
Macrophage contributes to radiation-induced anti-tumor abscopal effect on transplanted breast cancer by HMGB1/TNF-α signaling factors.
Zhu L, Hu S, Chen Q, Zhang H, Fu J, Zhou Y, Bai Y, Pan Y, Shao C
International journal of biological sciences 2021;17(4):926-941
International journal of biological sciences 2021;17(4):926-941
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Yu H, He B, Han X, Yan T
Open life sciences 2021;16(1):845-855
Open life sciences 2021;16(1):845-855
Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
Xie D, Zhao T, Zhang X, Kui L, Wang Q, Wu Y, Zheng T, Ma P, Zhang Y, Molteni H, Geng R, Yang Y, Li B, Zheng QY
Frontiers in cellular neuroscience 2021;15:753369
Frontiers in cellular neuroscience 2021;15:753369
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
Microarray analysis reveals a potential role of lncRNA expression in remote ischemic preconditioning in myocardial ischemia-reperfusion injury.
Lou Z, Wu W, Chen R, Xia J, Shi H, Ge H, Xue J, Wang H, Lin Z, Chu M, Zhao Q
American journal of translational research 2021;13(1):234-252
American journal of translational research 2021;13(1):234-252
Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.
Wang D, Song M, Shen LF, Han L, Zhu P, Jia X, Shang GK, Cao Y, Zhang W, Zhong M, Wang ZH
Frontiers in physiology 2021;12:786895
Frontiers in physiology 2021;12:786895
MNSFβ Regulates TNFα Production by Interacting with RC3H1 in Human Macrophages, and Dysfunction of MNSFβ in Decidual Macrophages Is Associated With Recurrent Pregnancy Loss.
Zhen XX, Yang L, Gu Y, Yang Q, Gu WW, He YP, Wang YL, Wang J
Frontiers in immunology 2021;12:691908
Frontiers in immunology 2021;12:691908
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
Zheng CQ, Fan HX, Li XX, Li JJ, Sheng S, Zhang F
Frontiers in immunology 2021;12:683577
Frontiers in immunology 2021;12:683577
A-Lipoic Acid Alleviates Folic Acid-Induced Renal Damage Through Inhibition of Ferroptosis.
Li X, Zou Y, Fu YY, Xing J, Wang KY, Wan PZ, Zhai XY
Frontiers in physiology 2021;12:680544
Frontiers in physiology 2021;12:680544
CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.
Li X, Tang X, Wang Y, Chai C, Zhao Z, Zhang H, Peng Y, Wu L
Frontiers in pharmacology 2021;12:655101
Frontiers in pharmacology 2021;12:655101
Ibudilast Attenuates Folic Acid-Induced Acute Kidney Injury by Blocking Pyroptosis Through TLR4-Mediated NF-κB and MAPK Signaling Pathways.
Li X, Zou Y, Fu YY, Xing J, Wang KY, Wan PZ, Wang M, Zhai XY
Frontiers in pharmacology 2021;12:650283
Frontiers in pharmacology 2021;12:650283
Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease.
Zhou Y, Wu M, Xu L, Cheng J, Shen J, Yang T, Zhang L
Frontiers in pharmacology 2021;12:640521
Frontiers in pharmacology 2021;12:640521
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Chen H, Yu B, Guo X, Hua H, Cui F, Guan Y, Tian Y, Zhang X, Zhang Y, Ma H
Frontiers in physiology 2021;12:639454
Frontiers in physiology 2021;12:639454
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Xu J, Tang Z, He Y, Cai S, Wang B, Zhang S, Wu M, Qian K, Zhang K, Chai B, Chen G, Xu K, Ji H, Xiao J, Wu Y
Frontiers in pharmacology 2021;12:628950
Frontiers in pharmacology 2021;12:628950
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
Chen R, Huang M, Yang X, Chen XH, Shi MY, Li ZF, Chen ZN, Wang K
Frontiers in oncology 2021;11:743050
Frontiers in oncology 2021;11:743050
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Zong RR, Zhu FF, Han W, Wang YX, Wang GL, Wang YZ, Mao YB, Guan TJ, Liu ZG, Xue YH, Li C
Journal of proteomics 2021 Sep 30;248:104351
Journal of proteomics 2021 Sep 30;248:104351
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging.
Jin Y, Kim EN, Lim JH, Kim HD, Ban TH, Yang CW, Park CW, Choi BS
Cells 2021 Sep 28;10(10)
Cells 2021 Sep 28;10(10)
Orexin-A Regulates Follicular Growth, Proliferation, Cell Cycle and Apoptosis in Mouse Primary Granulosa Cells via the AKT/ERK Signaling Pathway.
Safdar M, Liang A, Rajput SA, Abbas N, Zubair M, Shaukat A, Rehman AU, Jamil H, Guo Y, Ullah F, Yang L
Molecules (Basel, Switzerland) 2021 Sep 16;26(18)
Molecules (Basel, Switzerland) 2021 Sep 16;26(18)
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Ma X, Qin C, Chen M, Yu HH, Chu YH, Chen TJ, Bosco DB, Wu LJ, Bu BT, Wang W, Tian DS
Journal of neuroinflammation 2021 Sep 15;18(1):201
Journal of neuroinflammation 2021 Sep 15;18(1):201
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
Baicalin ameliorates cigarette smoke-induced airway inflammation in rats by modulating HDAC2/NF-κB/PAI-1 signalling.
Zhang H, Liu B, Jiang S, Wu JF, Qi CH, Mohammadtursun N, Li Q, Li L, Zhang H, Sun J, Dong JC
Pulmonary pharmacology & therapeutics 2021 Oct;70:102061
Pulmonary pharmacology & therapeutics 2021 Oct;70:102061
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
Li Y, Zeng N, Qin Z, Chen Y, Lu Q, Cheng Y, Xia Q, Lu Z, Gu N, Luo D
Nanoscale 2021 Oct 8;13(38):16104-16112
Nanoscale 2021 Oct 8;13(38):16104-16112
Neuroprotective effects of macamide from maca (Lepidium meyenii Walp.) on corticosterone-induced hippocampal impairments through its anti-inflammatory, neurotrophic, and synaptic protection properties.
Yu Z, Li D, Zhai S, Xu H, Liu H, Ao M, Zhao C, Jin W, Yu L
Food & function 2021 Oct 4;12(19):9211-9228
Food & function 2021 Oct 4;12(19):9211-9228
Cathepsin B Regulates Mice Granulosa Cells' Apoptosis and Proliferation In Vitro.
Chen C, Ahmad MJ, Ye T, Du C, Zhang X, Liang A, Yang L
International journal of molecular sciences 2021 Oct 31;22(21)
International journal of molecular sciences 2021 Oct 31;22(21)
Inflammation protein quantification by multiple reaction monitoring mass spectrometry in lipopolysaccharide-stimulated THP-1 cells.
Illiano A, Pinto G, Gaglione R, Arciello A, Amoresano A
Rapid communications in mass spectrometry : RCM 2021 Oct 30;35(20):e9166
Rapid communications in mass spectrometry : RCM 2021 Oct 30;35(20):e9166
Screen of anti-migraine active compounds from Duijinsan by spectrum-effect relationship analysis and molecular docking.
Zheng G, Gan L, Jia LY, Zhou DC, Bi S, Meng ZQ, Guan GJ, Huang MM, He X, Zhang CF, Wang CZ, Yuan CS
Journal of ethnopharmacology 2021 Oct 28;279:114352
Journal of ethnopharmacology 2021 Oct 28;279:114352
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Zhao K, Zhang J, Xu T, Yang C, Weng L, Wu T, Wu X, Miao J, Guo X, Tu J, Zhang D, Zhou B, Sun W, Kong X
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determined by a network pharmacology approach.
Li C, Wang M, Sui J, Zhou Y, Chen W
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1342-1353
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1342-1353
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Hong Y, Ren X, Liu W, Sun K, Chen B, Liu B, Yu X, Chen Q, Qian Q, Xie X, Jiang C
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles.
Yu Q, Tang X, Zhao W, Qiu Y, He J, Wan D, Li J, Wang X, He X, Liu Y, Li M, Zhang Z, He Q
Acta biomaterialia 2021 Oct 1;133:244-256
Acta biomaterialia 2021 Oct 1;133:244-256
miR‑4792 regulates inflammatory responses in Cryptococcus neoformans‑infected microglia.
Yao G, Wang X, Wang Y, Hou Q, Gao R, Wang Y, Teng L, Lin W, Wang Z, Jin Y, Chen J
International journal of molecular medicine 2021 Nov;48(5)
International journal of molecular medicine 2021 Nov;48(5)
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Gong Z, Liu G, Liu W, Zou H, Song R, Zhao H, Yuan Y, Gu J, Bian J, Zhu J, Liu Z
Ecotoxicology and environmental safety 2021 Nov;224:112620
Ecotoxicology and environmental safety 2021 Nov;224:112620
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Wang R, Wei L, Dong Z, Meng F, Wang G, Zhou S, Lan X, Liao Z, Chen M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 May;85:153548
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 May;85:153548
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Li W, Chen M, Feng X, Song M, Shao M, Yang Y, Zhang L, Liu Q, Lv L, Su X
Brain and behavior 2021 May;11(5):e02133
Brain and behavior 2021 May;11(5):e02133
Effects of carotid baroreceptor stimulation on aortic remodeling in obese rats.
Yu Q, Shu L, Wang L, Gao K, Wang J, Dai M, Cao Q, Zhang Y, Luo Q, Hu B, Dai D, Chen J, Bao M
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 May 6;31(5):1635-1644
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 May 6;31(5):1635-1644
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Qin H, Zhang H, Zhang X, Zhang S, Zhu S, Wang H
Biochemical and biophysical research communications 2021 May 21;554:199-205
Biochemical and biophysical research communications 2021 May 21;554:199-205
Alleviation of acute pancreatitis-associated lung injury by inhibiting the p38 mitogen-activated protein kinase pathway in pulmonary microvascular endothelial cells.
Zhang XX, Wang HY, Yang XF, Lin ZQ, Shi N, Chen CJ, Yao LB, Yang XM, Guo J, Xia Q, Xue P
World journal of gastroenterology 2021 May 14;27(18):2141-2159
World journal of gastroenterology 2021 May 14;27(18):2141-2159
The furin-S2' site in avian coronavirus plays a key role in central nervous system damage progression.
Cheng J, Zhao Y, Hu Y, Zhao J, Xue J, Zhang G
Journal of virology 2021 May 10;95(11)
Journal of virology 2021 May 10;95(11)
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Zhu S, Liu X, Xue M, Li Y, Cai D, Wang S, Zhang L
Journal of ginseng research 2021 Mar;45(2):295-304
Journal of ginseng research 2021 Mar;45(2):295-304
Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats.
Liu X, Man S, Luo C, Liu Y, Liu Y, Liu C, Gao W
Environmental toxicology 2021 Mar;36(3):386-395
Environmental toxicology 2021 Mar;36(3):386-395
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Zhang Y, Sun J, Dong Y, Shen X, Zhang Z
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation.
Zhang Q, Xiang E, Rao W, Zhang YQ, Xiao CH, Li CY, Han B, Wu D
Bone & joint research 2021 Mar;10(3):226-236
Bone & joint research 2021 Mar;10(3):226-236
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
Sanweidoukou decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: Studies in vivo and in vitro.
An FM, Liu Z, Xuan XR, Liu QS, Wei CX
Journal of ethnopharmacology 2021 Jun 12;273:114002
Journal of ethnopharmacology 2021 Jun 12;273:114002
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616
Food science & nutrition 2021 Jul;9(7):3602-3616
Luteolin ameliorates LPS-induced acute liver injury by inhibiting TXNIP-NLRP3 inflammasome in mice.
Wang X, Wang L, Dong R, Huang K, Wang C, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153586
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153586
Damage to the blood‑brain barrier and activation of neuroinflammation by focal cerebral ischemia under hyperglycemic condition.
Guo Y, Dong L, Gong A, Zhang J, Jing L, Ding T, Li PA, Zhang JZ
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
Pei L, Le Y, Chen H, Feng J, Liu Z, Zhu J, Wang C, Chen L, Dou X, Lu D
Fitoterapia 2021 Jul;152:104922
Fitoterapia 2021 Jul;152:104922
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Zhang H, Li S, Lu J, Jin J, Zhu G, Wang L, Yan Y, He L, Wang B, Wang X, Yu H
Aging 2021 Jul 8;13(13):17690-17706
Aging 2021 Jul 8;13(13):17690-17706
Critical Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers.
Flores-Toro J, Chun SK, Shin JK, Campbell J, Lichtenberger M, Chapman W, Zendejas I, Behrns K, Leeuwenburgh C, Kim JS
Cells 2021 Jul 23;10(8)
Cells 2021 Jul 23;10(8)
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Tang H, Zhang P, Zeng L, Zhao Y, Xie L, Chen B
Stem cell research & therapy 2021 Jul 16;12(1):409
Stem cell research & therapy 2021 Jul 16;12(1):409
Syringin exerts neuroprotective effects in a rat model of cerebral ischemia through the FOXO3a/NF-κB pathway.
Tan J, Luo J, Meng C, Jiang N, Cao J, Zhao J
International immunopharmacology 2021 Jan;90:107268
International immunopharmacology 2021 Jan;90:107268
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction.
Cai G, Cai G, Zhou H, Zhuang Z, Liu K, Pei S, Wang Y, Wang H, Wang X, Xu S, Cui C, Sun M, Guo S, Jia K, Wang X, Zhang D
Stem cell research & therapy 2021 Jan 6;12(1):2
Stem cell research & therapy 2021 Jan 6;12(1):2
Resolvin E1 accelerates pulp repair by regulating inflammation and stimulating dentin regeneration in dental pulp stem cells.
Chen J, Xu H, Xia K, Cheng S, Zhang Q
Stem cell research & therapy 2021 Jan 22;12(1):75
Stem cell research & therapy 2021 Jan 22;12(1):75
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
Fukuda M, Fukuda S, Ando J, Yamamoto K, Yonemoto N, Suzuki T, Niwa Y, Inoue T, Satoh-Asahara N, Hasegawa K, Shimatsu A, Tsukahara T
Journal of neurosurgery 2021 Jan 1;134(1):102-114
Journal of neurosurgery 2021 Jan 1;134(1):102-114
Hawthorn polyphenols reduce high glucose-induced inflammation and apoptosis in ARPE-19 cells by regulating miR-34a/SIRT1 to reduce acetylation.
Liu S, Fang Y, Yu J, Chang X
Journal of food biochemistry 2021 Feb;45(2):e13623
Journal of food biochemistry 2021 Feb;45(2):e13623
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Qiu C, Yang LD, Yu W, Tian DD, Gao MR, Wang WJ, Li XB, Wu YM, Wang M
Metabolic brain disease 2021 Feb;36(2):273-283
Metabolic brain disease 2021 Feb;36(2):273-283
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Yao Y, Liu T, Yin L, Man S, Ye S, Ma L
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Raw and wine processed Schisandra chinensis attenuate anxiety like behavior via modulating gut microbiota and lipid metabolism pathway.
Song Y, Shan B, Zeng S, Zhang J, Jin C, Liao Z, Wang T, Zeng Q, He H, Wei F, Ai Z, Su D
Journal of ethnopharmacology 2021 Feb 10;266:113426
Journal of ethnopharmacology 2021 Feb 10;266:113426
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Cheng L, Wang X, Ma X, Xu H, Yang Y, Zhang D
Pharmaceutical biology 2021 Dec;59(1):557-564
Pharmaceutical biology 2021 Dec;59(1):557-564
Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy.
Zhao L, Luo R, Yu H, Li S, Yu Q, Wang W, Cai K, Xu T, Chen R, Tian W
Iranian journal of basic medical sciences 2021 Dec;24(12):1734-1742
Iranian journal of basic medical sciences 2021 Dec;24(12):1734-1742
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Gu JY, Xu YW, Feng LP, Dong J, Zhao LQ, Liu C, Wang HY, Zhang XY, Song C, Wang CH
Brain research bulletin 2021 Dec;177:252-262
Brain research bulletin 2021 Dec;177:252-262
Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction.
Xiao Z, Kong B, Fang J, Qin T, Dai C, Shuai W, Huang H
Bioengineered 2021 Dec;12(2):9367-9376
Bioengineered 2021 Dec;12(2):9367-9376
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222
International immunopharmacology 2021 Dec;101(Pt B):108222
Long-term efavirenz exposure induced neuroinflammation and cognitive deficits in C57BL/6 mice.
Zhang R, Bao J, Qiao J, Li W, Qian F, Hu K, Sun B
Biochemical and biophysical research communications 2021 Dec 20;584:46-52
Biochemical and biophysical research communications 2021 Dec 20;584:46-52
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Immunoresponsive Tissue-Engineered Oral Mucosal Equivalents Containing Macrophages.
Ollington B, Colley HE, Murdoch C
Tissue engineering. Part C, Methods 2021 Aug;27(8):462-471
Tissue engineering. Part C, Methods 2021 Aug;27(8):462-471
METTL3/N6-methyladenosine/ miR-21-5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF-κB pathway activation.
Liu E, Lv L, Zhan Y, Ma Y, Feng J, He Y, Wen Y, Zhang Y, Pu Q, Ji F, Yang X, Wen JG
Journal of cellular and molecular medicine 2021 Aug;25(16):7660-7674
Journal of cellular and molecular medicine 2021 Aug;25(16):7660-7674
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
Qian K, Yuan L, Wang S, Kuang Y, Jin Q, Long D, Jiang Y, Zhao H, Liu K, Yao H
Clinical and experimental immunology 2021 Aug;205(2):246-256
Clinical and experimental immunology 2021 Aug;205(2):246-256
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Tian L, Wang S, Zhao L, Lu X, Zhu C, Gong H, Yang W
FEBS open bio 2021 Aug;11(8):2236-2244
FEBS open bio 2021 Aug;11(8):2236-2244
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Yu B, Chen H, Guo XQ, Hua H, Guan Y, Cui F, Tian YM, Zhang HX, Zhang XJ, Zhang Y, Ma HJ
Life sciences 2021 Aug 1;278:119540
Life sciences 2021 Aug 1;278:119540
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Tian S, Liao L, Zhou Q, Huang X, Zheng P, Guo Y, Deng T, Tian X
Oncology letters 2021 Apr;21(4):286
Oncology letters 2021 Apr;21(4):286
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Regulatory effects of hawthorn polyphenols on hyperglycemic, inflammatory, insulin resistance responses, and alleviation of aortic injury in type 2 diabetic rats.
Liu S, Yu J, Fu M, Wang X, Chang X
Food research international (Ottawa, Ont.) 2021 Apr;142:110239
Food research international (Ottawa, Ont.) 2021 Apr;142:110239
High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke.
Hu M, Lin Y, Men X, Wang S, Sun X, Zhu Q, Lu D, Liu S, Zhang B, Cai W, Lu Z
Journal of neuroinflammation 2021 Apr 12;18(1):90
Journal of neuroinflammation 2021 Apr 12;18(1):90
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Silencing lncRNA TUG1 Alleviates LPS-Induced Mouse Hepatocyte Inflammation by Targeting miR-140/TNF.
Liu QM, Liu LL, Li XD, Tian P, Xu H, Li ZL, Wang LK
Frontiers in cell and developmental biology 2020;8:616416
Frontiers in cell and developmental biology 2020;8:616416
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Shao Z, Tu Z, Shi Y, Li S, Wu A, Wu Y, Tian N, Sun L, Pan Z, Chen L, Gao W, Zhou Y, Wang X, Zhang X
Frontiers in cell and developmental biology 2020;8:611234
Frontiers in cell and developmental biology 2020;8:611234
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Gastroprotective Activity of the Total Flavones from Abelmoschus manihot (L.) Medic Flowers.
Zhang J, Fu ZL, Chu ZX, Song BW
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6584945
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6584945
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Deng Y, Yang L, Xie Q, Yang F, Li G, Zhang G, Li S, Wu Z, Wang J, Kang X
Mediators of inflammation 2020;2020:6420425
Mediators of inflammation 2020;2020:6420425
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Li X, Zou Y, Xing J, Fu YY, Wang KY, Wan PZ, Zhai XY
Oxidative medicine and cellular longevity 2020;2020:6286984
Oxidative medicine and cellular longevity 2020;2020:6286984
The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells.
Sun H, Ding JM, Zheng HH, Lv KJ, Hu YF, Luo YH, Wu X, Pei WJ, Wang LZ, Wu MC, Zhang Y, Gao JL
Mediators of inflammation 2020;2020:3560793
Mediators of inflammation 2020;2020:3560793
Effect of Moxibustion on the Intestinal Flora of Rats with Knee Osteoarthritis Induced by Monosodium Iodoacetate.
Chen Y, Lv J, Jia Y, Wang R, Zhang Z, Liu J, Jia C
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3196427
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3196427
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
He XM, Zhou YZ, Sheng S, Li JJ, Wang GQ, Zhang F
Oxidative medicine and cellular longevity 2020;2020:2963540
Oxidative medicine and cellular longevity 2020;2020:2963540
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, An T, Chen Y, Zhang X
International journal of nanomedicine 2020;15:3415-3431
International journal of nanomedicine 2020;15:3415-3431
Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats.
Lin J, Huang Z, Liu J, Huang Z, Liu Y, Liu Q, Yang Z, Li R, Wu X, Shi Z, Zhu Q, Wu X
Frontiers in neuroscience 2020;14:583611
Frontiers in neuroscience 2020;14:583611
Effect of AAV9-hIGF-1 on inflammatory reaction in mdx mice and its mechanism.
Ji G, Sun S, Wu H, Chen X, Cui H, Tang J, Lu S, Lu Y, Li D, Song X
American journal of translational research 2020;12(8):4488-4497
American journal of translational research 2020;12(8):4488-4497
Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation.
Lin G, Li X, Cheng X, Zhao N, Zheng W
Frontiers in aging neuroscience 2020;12:556008
Frontiers in aging neuroscience 2020;12:556008
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Zhou XL, Yang J, Qu XJ, Meng J, Miao RR, Cui SX
Frontiers in pharmacology 2020;11:557312
Frontiers in pharmacology 2020;11:557312
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Wan YM, Wu HM, Li YH, Xu ZY, Yang JH, Liu C, He YF, Wang MJ, Wu XN, Zhang Y
Frontiers in pharmacology 2020;11:10
Frontiers in pharmacology 2020;11:10
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Liu C, Ding R, Huang W, Miao L, Li J, Li Y
Pharmacology 2020;105(3-4):231-242
Pharmacology 2020;105(3-4):231-242
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Zhang S, Zhang H, Jin Z, Wang S, Wang Y, Zhu L, Sun W, Yan B
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Chen Y, Lu Y, Pei C, Liang J, Ding P, Chen S, Hou SZ
European journal of pharmacology 2020 Sep 15;883:173358
European journal of pharmacology 2020 Sep 15;883:173358
BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway.
Xu B, Gan CX, Chen SS, Li JQ, Liu MZ, Guo GH
Life sciences 2020 Sep 15;257:118042
Life sciences 2020 Sep 15;257:118042
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Li S, Shi M, Wan Y, Wang Y, Zhu M, Wang B, Zhan Y, Ran B, Wu C
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Liu X, Hao J, Yao E, Cao J, Zheng X, Yao D, Zhang C, Li J, Pan D, Luo X, Wang M, Wang W
Brain, behavior, and immunity 2020 Oct;89:357-370
Brain, behavior, and immunity 2020 Oct;89:357-370
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
You M, Miao Z, Tian J, Hu F
European journal of nutrition 2020 Oct;59(7):2875-2892
European journal of nutrition 2020 Oct;59(7):2875-2892
C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation.
Yan C, Zhang L, Yang L, Zhang Q, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13696-13710
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13696-13710
Protective effect of astaxanthin against La(2)O(3) nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Yuan L, Qu Y, Li Q, An T, Chen Z, Chen Y, Deng X, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
Fu XP, Xu L, Fu BB, Wei KN, Liu Y, Liao BQ, He SW, Wang YL, Chen MH, Lin YH, Li FP, Hong ZW, Huang XH, Xu CL, Wang HL
Biology of reproduction 2020 Oct 29;103(5):1085-1098
Biology of reproduction 2020 Oct 29;103(5):1085-1098
Dihydroartemisinin prevents dextran sodium sulphate-induced colitisthrough inhibition of the activation of NLRP3 inflammasome and p38 MAPK signaling.
Liang R, Chen W, Fan H, Chen X, Zhang J, Zhu JS
International immunopharmacology 2020 Nov;88:106949
International immunopharmacology 2020 Nov;88:106949
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Yuan L, Liang P, Qu Y, An T, Wang J, Deng X, Bai L, Shen P, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Man S, Yang L, Xiang H, Lu G, Wang Y, Liu C, Gao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats.
Fang D, Lin Q, Wang C, Zheng C, Li Y, Huang T, Ni F, Wu Z, Chen B, Sun L
International immunopharmacology 2020 Mar;80:106151
International immunopharmacology 2020 Mar;80:106151
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y
International immunopharmacology 2020 Mar;80:106123
International immunopharmacology 2020 Mar;80:106123
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Zhang P, Yi L, Qu S, Dai J, Li X, Liu B, Li H, Ai K, Zheng P, Qiu S, Li Y, Wang Y, Xiang X, Chai X, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Wu N, Ye C, Zheng F, Wan GW, Wu LL, Chen Q, Li YH, Kang YM, Zhu GQ
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D
Journal of food science 2020 Jun;85(6):1872-1890
Journal of food science 2020 Jun;85(6):1872-1890
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, Mu M, Xing M
Biological trace element research 2020 Jun;195(2):613-623
Biological trace element research 2020 Jun;195(2):613-623
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Zeng Z, Gong X, Hu Z
Aging 2020 Jun 21;12(12):11768-11780
Aging 2020 Jun 21;12(12):11768-11780
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Yang B, Qin Q, Xu L, Lv X, Liu Z, Song E, Song Y
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, Chu L
International immunopharmacology 2020 Jul;84:106548
International immunopharmacology 2020 Jul;84:106548
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F
International immunopharmacology 2020 Jul;84:106501
International immunopharmacology 2020 Jul;84:106501
Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa B signaling in hepatic stellate cells.
Jia Y, Gao L, Yang X, Zhang F, Chen A, Wang S, Shao J, Tan S, Zheng S
Toxicology 2020 Jul;440:152475
Toxicology 2020 Jul;440:152475
Gut microbiome-derived lactate promotes to anxiety-like behaviors through GPR81 receptor-mediated lipid metabolism pathway.
Shan B, Ai Z, Zeng S, Song Y, Song J, Zeng Q, Liao Z, Wang T, Huang C, Su D
Psychoneuroendocrinology 2020 Jul;117:104699
Psychoneuroendocrinology 2020 Jul;117:104699
Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine.
Song I, Ise H
Polymers 2020 Jul 7;12(7)
Polymers 2020 Jul 7;12(7)
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Man S, Yao J, Lv P, Liu Y, Yang L, Ma L
Food & function 2020 Jul 22;11(7):6422-6432
Food & function 2020 Jul 22;11(7):6422-6432
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Wang D, Zong C, Cheng K
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats.
Zhang Z, Ji J, Zhang D, Ma M, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153110
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153110
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701
Cell proliferation 2020 Jan;53(1):e12701
MST4 modulates the neuro-inflammatory response by regulating IκBα signaling pathway and affects the early outcome of experimental ischemic stroke in mice.
Luan D, Zhang Y, Yuan L, Chu Z, Ma L, Xu Y, Zhao S
Brain research bulletin 2020 Jan;154:43-50
Brain research bulletin 2020 Jan;154:43-50
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, Xia K, Feng X, Li Y, Liang X, Sun X, Deng C, Liu G
Aging 2020 Jan 20;12(2):1272-1284
Aging 2020 Jan 20;12(2):1272-1284
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Zhang H, Chen Y, Chen Y, Li Y, Jia P, Ji S, Zhou Y, Wang T
Journal of animal science 2020 Jan 1;98(1)
Journal of animal science 2020 Jan 1;98(1)
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Dexmedetomidine Inhibits Neuroinflammation by Altering Microglial M1/M2 Polarization Through MAPK/ERK Pathway.
Qiu Z, Lu P, Wang K, Zhao X, Li Q, Wen J, Zhang H, Li R, Wei H, Lv Y, Zhang S, Zhang P
Neurochemical research 2020 Feb;45(2):345-353
Neurochemical research 2020 Feb;45(2):345-353
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Li M, Fang XZ, Liu XT, Zheng YF, Xie YB, Ma XD, Xia Y, Shao DH
Molecular medicine reports 2020 Feb;21(2):607-614
Molecular medicine reports 2020 Feb;21(2):607-614
The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection.
Li C, Li C, Lin J, Zhao G, Xu Q, Jiang N, Wang Q, Peng X, Zhu G, Jiang J
Investigative ophthalmology & visual science 2020 Feb 7;61(2):25
Investigative ophthalmology & visual science 2020 Feb 7;61(2):25
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Yang L, Sun YY, Liu YR, Yin NN, Bu FT, Yu HX, Du XS, Li J, Huang C
Toxicology letters 2020 Feb 1;319:11-21
Toxicology letters 2020 Feb 1;319:11-21
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, Yang W, Zhang R, Tang Y, Shi L, Li R, Tao K
Free radical biology & medicine 2020 Feb 1;147:23-36
Free radical biology & medicine 2020 Feb 1;147:23-36
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Liu M, Li W, Song F, Zhang L, Sun X
Aging 2020 Dec 9;13(2):2506-2518
Aging 2020 Dec 9;13(2):2506-2518
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Liu JH, Yue T, Luo ZW, Cao J, Yan ZQ, Jin L, Wan TF, Shuai CJ, Wang ZG, Zhou Y, Xu R, Xie H
Disease models & mechanisms 2020 Dec 1;13(11)
Disease models & mechanisms 2020 Dec 1;13(11)
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Han J, Kan J, Wang X, Yuan Q, Song X, Huang M, Wu H
Translational cancer research 2020 Aug;9(8):4715-4725
Translational cancer research 2020 Aug;9(8):4715-4725
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8(+) T cells.
Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G, Rana B, Rana A
Journal for immunotherapy of cancer 2020 Aug;8(2)
Journal for immunotherapy of cancer 2020 Aug;8(2)
The effect of astaxanthin on inflammation in hyperosmolarity of experimental dry eye model in vitro and in vivo.
Li H, Li J, Hou C, Li J, Peng H, Wang Q
Experimental eye research 2020 Aug;197:108113
Experimental eye research 2020 Aug;197:108113
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Song L, Piao Z, Yao L, Zhang L, Lu Y
Experimental animals 2020 Aug 5;69(3):363-373
Experimental animals 2020 Aug 5;69(3):363-373
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Luo J, Yang C, Luo X, Yang Y, Li J, Song B, Zhao J, Li L
Life sciences 2020 Aug 1;254:117590
Life sciences 2020 Aug 1;254:117590
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205
International immunopharmacology 2020 Apr;81:106205
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Ye S, Chen Q, Jiang N, Liang X, Li J, Zong R, Huang C, Qiu Y, Ma JX, Liu Z
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment.
Liu Y, Zhang X, Yan D, Wang Y, Wang N, Liu Y, Tan A, Chen X, Yan H
Toxicology and applied pharmacology 2020 Apr 15;393:114949
Toxicology and applied pharmacology 2020 Apr 15;393:114949
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Vagus Nerve Stimulation Attenuates Acute Skeletal Muscle Injury Induced by Ischemia-Reperfusion in Rats.
Zhang Y, Li H, Wang M, Meng G, Wang Z, Deng J, Wang M, Zhang Q, Yang S, Jiang H
Oxidative medicine and cellular longevity 2019;2019:9208949
Oxidative medicine and cellular longevity 2019;2019:9208949
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Yang Y, Pang B, Liu Z, Li J, Zhang Z, Zhang R, Hou X, Guo H, Chi L, Pang Q, Xin T
Oxidative medicine and cellular longevity 2019;2019:1292891
Oxidative medicine and cellular longevity 2019;2019:1292891
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Chen J, Li D, Luo E
International immunopharmacology 2019 Sep;74:105683
International immunopharmacology 2019 Sep;74:105683
Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis.
Sun Y, Pan W, Zhang J, Cui Y, Wang H, Ru G, Chen L
International journal of molecular medicine 2019 Sep;44(3):1106-1116
International journal of molecular medicine 2019 Sep;44(3):1106-1116
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Ding XF, Liang HY, Sun JY, Liu SH, Kan QC, Wang LX, Sun TW
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection.
Geng ZK, Li YQ, Cui QH, DU RK, Tian JZ
Chinese journal of natural medicines 2019 Sep;17(9):650-662
Chinese journal of natural medicines 2019 Sep;17(9):650-662
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Wang G, Zhou Y, Wang Y, Li D, Liu J, Zhang F
Neuroscience 2019 Sep 1;415:89-96
Neuroscience 2019 Sep 1;415:89-96
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K
International immunopharmacology 2019 Oct;75:105715
International immunopharmacology 2019 Oct;75:105715
Effects of ubiquitin-proteasome inhibitor on the expression levels of TNF-α and TGF-β1 in mice with viral myocarditis.
Zhang H, Yu J, Sun H, Zhao Y, Wang J, Zhang J, Meng B
Experimental and therapeutic medicine 2019 Oct;18(4):2799-2804
Experimental and therapeutic medicine 2019 Oct;18(4):2799-2804
Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1.
Liang H, Ding X, Yu Y, Zhang H, Wang L, Kan Q, Ma S, Guan F, Sun T
Experimental cell research 2019 Oct 1;383(1):111465
Experimental cell research 2019 Oct 1;383(1):111465
Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation.
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin XY, Kojima S, Fujimoto J
Scientific reports 2019 Nov 26;9(1):17558
Scientific reports 2019 Nov 26;9(1):17558
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, Fan X, Guo C, Wu J
International immunopharmacology 2019 May;70:435-445
International immunopharmacology 2019 May;70:435-445
Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy.
Shang J, Wang L, Zhang Y, Zhang S, Ning L, Zhao J, Cheng G, Liu D, Xiao J, Zhao Z
Journal of cellular and molecular medicine 2019 May;23(5):3417-3428
Journal of cellular and molecular medicine 2019 May;23(5):3417-3428
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice.
Wang Z, Zhou L, An D, Xu W, Wu C, Sha S, Li Y, Zhu Y, Chen A, Du Y, Chen L, Chen L
Cell death & disease 2019 May 16;10(6):386
Cell death & disease 2019 May 16;10(6):386
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Zhang L, Li HX, Pan WS, Ullah Khan F, Qian C, Qi-Li FR, Xu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Wang R, Dong Z, Lan X, Liao Z, Chen M
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway.
Lan H, Su Y, Liu Y, Deng C, Wang J, Chen T, Jules KED, Masau JF, Li H, Wei X
Life sciences 2019 Jul 1;228:35-46
Life sciences 2019 Jul 1;228:35-46
Macrophage polarization in human gingival tissue in response to periodontal disease.
Zhou LN, Bi CS, Gao LN, An Y, Chen F, Chen FM
Oral diseases 2019 Jan;25(1):265-273
Oral diseases 2019 Jan;25(1):265-273
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity and inhibiting inflammation.
Han XX, Jiang YP, Liu N, Wu J, Yang JM, Li YX, Sun M, Sun T, Zheng P, Jian-Qiang Yu
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:561-570
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:561-570
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Chai S, Liu K, Feng W, Liu T, Wang Q, Zhou R, Chen S, Wang L, Chen G, Ming T, Zhao J, Liu C, Xue B
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy.
Huang X, Wu B, Li J, Shang Y, Chen W, Nie X, Gui R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):968-979
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):968-979
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
Zhao H, Wang Y, Guo M, Fei D, Mu M, Yu H, Xing M
Chemosphere 2019 Dec;236:124869
Chemosphere 2019 Dec;236:124869
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis by regulating fatty acid degradation and microbial dysbiosis.
Chen W, Fan H, Liang R, Zhang R, Zhang J, Zhu J
Journal of cellular and molecular medicine 2019 Dec;23(12):8161-8172
Journal of cellular and molecular medicine 2019 Dec;23(12):8161-8172
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, Guo Y, Han H
Virulence 2019 Dec;10(1):248-259
Virulence 2019 Dec;10(1):248-259
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.
Li Q, Sun J, Mohammadtursun N, Wu J, Dong J, Li L
Food & function 2019 Dec 11;10(12):7983-7994
Food & function 2019 Dec 11;10(12):7983-7994
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Mousavi M, Hedayatpour A, Mortezaee K, Mohamadi Y, Abolhassani F, Hassanzadeh G
Metabolic brain disease 2019 Aug;34(4):1117-1130
Metabolic brain disease 2019 Aug;34(4):1117-1130
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Zhu QJ, Zhu M, Xu XX, Meng XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
Effects of intrahepatic cholestasis of pregnancy on hepatic function, changes of inflammatory cytokines and fetal outcomes.
Wang L, Lu Z, Zhou X, Ding Y, Guan L
Experimental and therapeutic medicine 2019 Apr;17(4):2979-2984
Experimental and therapeutic medicine 2019 Apr;17(4):2979-2984
Changes in expression of p53 and inflammatory factors in patients with ulcerative colitis.
Su H, Kang Q, Wang H, Yin H, Duan L, Liu Y, Fan R
Experimental and therapeutic medicine 2019 Apr;17(4):2451-2456
Experimental and therapeutic medicine 2019 Apr;17(4):2451-2456
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Zhang X, Li X, Liu N, Zheng P, Ma L, Guo F, Sun T, Zhou R, Yu J
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis.
Fukuda D, Nishimoto S, Aini K, Tanaka A, Nishiguchi T, Kim-Kaneyama JR, Lei XF, Masuda K, Naruto T, Tanaka K, Higashikuni Y, Hirata Y, Yagi S, Kusunose K, Yamada H, Soeki T, Imoto I, Akasaka T, Shimabukuro M, Sata M
Journal of the American Heart Association 2019 Apr 2;8(7):e010860
Journal of the American Heart Association 2019 Apr 2;8(7):e010860
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Rao SS, Hu Y, Xie PL, Cao J, Wang ZX, Liu JH, Yin H, Huang J, Tan YJ, Luo J, Luo MJ, Tang SY, Chen TH, Yuan LQ, Liao EY, Xu R, Liu ZZ, Chen CY, Xie H
Bone research 2018;6:9
Bone research 2018;6:9
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
Antichronic Gastric Ulcer Effect of Zinc-Baicalin Complex on the Acetic Acid-Induced Chronic Gastric Ulcer Rat Model.
Yang H, Lu Y, Zeng XF, Li L, Zhang RP, Ren ZK, Liu X
Gastroenterology research and practice 2018;2018:1275486
Gastroenterology research and practice 2018;2018:1275486
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Zhang B, Wei YZ, Wang GQ, Li DD, Shi JS, Zhang F
Frontiers in cellular neuroscience 2018;12:531
Frontiers in cellular neuroscience 2018;12:531
Boxb mediate BALB/c mice corneal inflammation through a TLR4/MyD88-dependent signaling pathway in Aspergillus fumigatus keratitis.
Liu M, Li C, Zhao GQ, Lin J, Che CY, Xu Q, Wang Q, Xu R, Niu YW
International journal of ophthalmology 2018;11(4):548-552
International journal of ophthalmology 2018;11(4):548-552
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lu DS, Chen C, Zheng YX, Li DD, Wang GQ, Liu J, Shi J, Zhang F
Frontiers in molecular neuroscience 2018;11:155
Frontiers in molecular neuroscience 2018;11:155
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Liver injury induced in Balb/c mice by PM(2.5) exposure and its alleviation by compound essential oils.
Ya P, Xu H, Ma Y, Fang M, Yan X, Zhou J, Li F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:590-598
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:590-598
Three-Dimensionally Printed Silk-Sericin-Based Hydrogel Scaffold: A Promising Visualized Dressing Material for Real-Time Monitoring of Wounds.
Chen CS, Zeng F, Xiao X, Wang Z, Li XL, Tan RW, Liu WQ, Zhang YS, She ZD, Li SJ
ACS applied materials & interfaces 2018 Oct 10;10(40):33879-33890
ACS applied materials & interfaces 2018 Oct 10;10(40):33879-33890
scAAV9-VEGF-165 inhibits neuroinflammatory responses and invasion of macrophages into the peripheral nervous system of ALS transgenic mice.
Wang Y, Liu Y, Zhai J, Duan W, Sun S, Cui H, Chen X, Ji J, Liu Y
Brain research bulletin 2018 Jun;140:233-242
Brain research bulletin 2018 Jun;140:233-242
Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines.
Wang Y, Zhao H, Liu J, Shao Y, Li J, Luo L, Xing M
International immunopharmacology 2018 Jul;60:64-75
International immunopharmacology 2018 Jul;60:64-75
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, Jin T, Lin Z, Ma Y, Yang X, Xia Q, Xue P
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Cai W, Zhang Z, Huang Y, Sun H, Qiu L
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Guan Y, Tan Y, Liu W, Yang J, Wang D, Pan D, Sun Y, Zheng C
Digestive diseases and sciences 2018 Feb;63(2):366-380
Digestive diseases and sciences 2018 Feb;63(2):366-380
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
HMGB1 mediates depressive behavior induced by chronic stress through activating the kynurenine pathway.
Wang B, Lian YJ, Su WJ, Peng W, Dong X, Liu LL, Gong H, Zhang T, Jiang CL, Wang YX
Brain, behavior, and immunity 2018 Aug;72:51-60
Brain, behavior, and immunity 2018 Aug;72:51-60
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Dong Y, Xu M, Kalueff AV, Song C
European journal of nutrition 2018 Aug;57(5):1781-1791
European journal of nutrition 2018 Aug;57(5):1781-1791
Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation.
Sun D, Ma H, Ma J, Wang J, Deng X, Hu C, Deng X
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Zhou SH, Wang X, Fan MY, Li HL, Bian F, Huang T, Fang HY
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, Wu S, Jin G, Bai Y
Biochemical pharmacology 2018 Aug;154:203-212
Biochemical pharmacology 2018 Aug;154:203-212
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine.
Gong Q, Zou R, Xing J, Xiang L, Zhang R, Wu A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Apr;5(4):1700664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2018 Apr;5(4):1700664
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
Huang C, Zhu L, Li H, Shi FG, Wang GQ, Wei YZ, Liu J, Zhang F
Frontiers in molecular neuroscience 2017;10:131
Frontiers in molecular neuroscience 2017;10:131
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Zhang L, Li Z, Ding G, La X, Yang P, Li Z
Cellular signalling 2017 Sep;37:136-148
Cellular signalling 2017 Sep;37:136-148
Prediction and identification of B‑cell epitopes for tumor necrosis factor‑α.
Zhang J, Cui Y, Wu Y, Wang H, Ke J
Molecular medicine reports 2017 Sep;16(3):3439-3444
Molecular medicine reports 2017 Sep;16(3):3439-3444
Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice.
Xu S, Wu L, Zhang Q, Feng J, Li S, Li J, Liu T, Mo W, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Life sciences 2017 Sep 15;185:103-113
Life sciences 2017 Sep 15;185:103-113
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Ren X, Fu X, Zhang X, Chen S, Huang S, Yao L, Liu G
Biochemical pharmacology 2017 Sep 15;140:73-88
Biochemical pharmacology 2017 Sep 15;140:73-88
NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus.
Li S, Wang Y, Zhao H, He Y, Li J, Jiang G, Xing M
Chemosphere 2017 Oct;185:618-627
Chemosphere 2017 Oct;185:618-627
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Qiu Y, Sui X, Cao S, Li X, Ning Y, Wang S, Yin L, Zhi X
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, Mao Y, Chen L, Zhang R, Li W
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Zhao X, Chen Z, Yin Y, Li X
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
Ren H, Hu K
Molecular medicine reports 2017 Dec;16(6):8092-8102
Molecular medicine reports 2017 Dec;16(6):8092-8102
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Chen L, Liu T, Wang Q, Liu J
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31
International immunopharmacology 2016 Sep;38:120-31
Perfluorooctane Sulfonate Induces Autophagy-Dependent Apoptosis through Spinster 1-Mediated lysosomal-Mitochondrial Axis and Impaired Mitophagy.
Yao X, Sha S, Wang Y, Sun X, Cao J, Kang J, Jiang L, Chen M, Ma Y
Toxicological sciences : an official journal of the Society of Toxicology 2016 Sep;153(1):198-211
Toxicological sciences : an official journal of the Society of Toxicology 2016 Sep;153(1):198-211
p38 mitogen-activated protein kinase inhibition modulates nucleus pulposus cell apoptosis in spontaneous resorption of herniated intervertebral discs: An experimental study in rats.
Zhu Y, Liu JT, Yang LY, Du WP, Li XC, Qian X, Yu PF, Liu JW, Jiang H
Molecular medicine reports 2016 May;13(5):4001-6
Molecular medicine reports 2016 May;13(5):4001-6
Elevated Level of Circulating Platelet-derived Microparticles in Oral Cancer.
Ren JG, Man QW, Zhang W, Li C, Xiong XP, Zhu JY, Wang WM, Sun ZJ, Jia J, Zhang WF, Zhao YF, Chen G, Liu B
Journal of dental research 2016 Jan;95(1):87-93
Journal of dental research 2016 Jan;95(1):87-93
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
Gong Y, Li H, Li Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats.
Fang T, Zhou D, Lu L, Tong X, Wu J, Yi L
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2016 Aug 1;49(9):e5287
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2016 Aug 1;49(9):e5287
MicroRNA-499 Rs3746444 polymorphism and biliary atresia.
Shan Y, Shen N, Han L, Chen Q, Zhang J, Long X, Xia Q
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2016 Apr;48(4):423-8
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2016 Apr;48(4):423-8
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Li X, Yang J, Liu D, Li J, Niu K, Feng S, Yokota H, Zhang P
Scientific reports 2016 Apr 18;6:24668
Scientific reports 2016 Apr 18;6:24668
Relationship between irradiation-induced neuro-inflammatory environments and impaired cognitive function in the developing brain of mice.
Dong X, Luo M, Huang G, Zhang J, Tong F, Cheng Y, Cai Q, Dong J, Wu G, Cheng J
International journal of radiation biology 2015 Mar;91(3):224-39
International journal of radiation biology 2015 Mar;91(3):224-39
Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice.
Gu Y, He Y, Zhang X, Shi Y, Yang Q, Yu L, Sun Z, Zhang H, Wang J, Gao X, Wang J
Molecular reproduction and development 2015 Jun;82(6):475-88
Molecular reproduction and development 2015 Jun;82(6):475-88
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo.
Yang T, Shi R, Chang L, Tang K, Chen K, Yu G, Tian Y, Guo Y, He W, Song X, Xu H, Ye Z
Journal of experimental & clinical cancer research : CR 2015 Feb 25;34(1):21
Journal of experimental & clinical cancer research : CR 2015 Feb 25;34(1):21
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Wen J, Zeng M, Shu Y, Guo D, Sun Y, Guo Z, Wang Y, Liu Z, Zhou H, Zhang W
Age (Dordrecht, Netherlands) 2015 Dec;37(6):112
Age (Dordrecht, Netherlands) 2015 Dec;37(6):112
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 17590-1-AP(TNFA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TNF-alpha antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TNF-alpha. This antibody recognizes human antigen. The TNF-alpha antibody has been validated for the following applications: ELISA, IHC analysis.
