ENTPD4

This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]

Description

Ectonucleoside triphosphate diphosphohydrolase 4

Tissue specificity

Low tissue specificity

Subcell location

Vesicles

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

8 (23385783 - 23457695)

Ensembl ID

ENSG00000197217  (ver. 103.38)

Orthologs

-

UniProt

Q9Y227

neXtProt

NX_Q9Y227

Human splice variants

Protein structure