BS8261

antibody from Bioworld Technology, Inc

Targeting: PRUNE2 A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8261

Provider

Bioworld Technology, Inc

Product name

PRUNE2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human PRUNE2.

Description

PRUNE2 (prune homolog 2 (Drosophila)), also known as BMCC1 (BNIP2 motif-containing molecule at the C-terminal region 1) or BNIPXL, is a 3,088 amino acid cytoplasmic protein that belongs to the PPase class C family and PRUNE subfamily. PRUNE2 is involved in the survival and aggressiveness of tumor cells and may also play a role in differentiation. Highly expressed in the nervous system and adrenal gland, PRUNE2 exists as five alternatively spliced isoforms and is induced during the G1 phase of the cell cycle. PRUNE2 contains one CRAL-TRIO domain and is encoded by a gene that maps to human chromosome 9q21.13. Chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.